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10篇 您的检索式:作者名="Claudia Fuchs"
    题名 作者 年代 出处 被引量
1立方体宾馆 瑞士 萨沃宁显示文摘在瑞士格劳宾登州的萨沃宁市城郊,你能够看到一座引人注目的特殊建筑:一座四层的玻璃立方体建筑,也就是“立方体”宾馆。Claudia Fuchs 2008城市建筑2008,,9:1
2Software improvement for evaluation of laryngopharyngeal pH testing(Restech)——a comparison between Data View 3 and 4显示文摘BACKGROUND When gastroesophageal reflux contents reach above the upper esophageal sphincter,patients may,in addition to typical reflux symptoms,present with atypical,extraesophageal symptoms related to laryngopharyngeal reflux(LPR).Surgical treatment of LPR has shown to lead to 70%symptom improvement,however no gold standard for the diagnosis of LPR exists.In 2007,the Restech Dx-pH was released as a valid method to measure acid exposure above the upper esophageal sphincter.Recently,a new software update was introduced for analysis of measured pH data and calculation of composite scores.The effect of the changes applied to the new software version have not yet been analyzed.AIM To compare results generated by Data View 3 to the most recently released Data View 4.METHODS All patients with gastroesophageal reflux disease symptoms were seen in a specialized surgical outpatient clinic for gastrointestinal function testing.Retrospective chart review was performed of all patients presenting with suspected gastroesophageal reflux disease and extraesophageal reflux symptoms,who underwent laryngopharyngeal pH monitoring using the Restech Dx-pH system(Respiratory Technology Corp.,Houston,TX,United States)and simultaneous esophageal pH monitoring.Data View 3 and Data View 4 were used to evaluate Restech studies obtained.Diary entries such as mealtimes,supine and upright periods,and symptoms were entered manually to ensure accuracy and precise conversion of data between both software versions.Paired t test was performed for statistical analysis of results.RESULTS A total of 174 patients(63.8%female)met inclusion criteria,all suffering from extraesophageal reflux symptoms as well as typical gastroesophageal reflux disease symptoms.Mean RYAN score upright was 48.77 in Data View 3 compared to 22.17 in Data View 4,showing a significant difference(~aP=0.0001).Similar results were shown for supine period(mean RYAN Score Data View 35.29 vs 1.42 in Data View 4,~cP=0.0001).For upright periods 80 patients showed a decrease of value of the RYAN score with a mean of-58.9(mean 51.1%decrease).For supine position 25 patients showed a decrease of value of the RYAN score with a mean of-15.13[range(-153.44)–(-0.01)],which equals a mean decrease of value of 44.5%.Ten patients showed no oropharyngeal acid exposure in Data View 3,but mild/moderate(n=7)or severe(n=3)acid exposure in Data View 4.Correlation with positive esophageal pH measurement was improved in all 10 patients.CONCLUSION Results of both software versions cannot be compared to each other.However,our data suggests that Data View 4 may be an improvement of the Restech pH measurement in the evaluation of LPR.Dolores Thea Müller Elena Schulte Benjamin Babic Laura Knepper Claudia Fuchs Wolfgang Schroder Christiane J Bruns Jessica M Leers Hans Friedrich Fuchs 2020World Journal of Gastrointestinal Surgery2020,12,5:1
3Anisotropy of transcallosal motor fibres indicates functional impairment in children with periventricular leukomalacia显示文摘Koerte Inga Pelavin Paula Kirmess Berit Fuchs Teresa Berweck Steffen Laubender Ruediger P Borggraefe Ingo Schroeder Sebastian Danek Adrian Rummeny Claudia Reiser Maximilian Kubicki Marek Shenton Martha E Ertl-Wagner Birgit Heinen Florian 2011Developmental Medicine and Child Neurology2011,,2:1
4Hemispheric differences in basilar den- drites and spines of pyramidal neurons in the rat prelim- bic cortex:activity- and stress-induced changes 显示文摘Claudia Perez-Cruz Maria Simon Boldizsar Czeh Eber- hard Fuchs 2009Eu- ropean Journal of the Neurosciences2009,29,:1
5The Amyloid Precursor Protein (APP) Triplicated Gene Impairs Neuronal Precursor Differentiation and Neurite Development through Two Different Domains in the Ts65Dn Mouse Model for Down Syndrome显示文摘Stefania Trazzi Claudia Fuchs Emanuele Valli Giovanni Perini Renata Bartesaghi Elisabetta Ciani 2013Journal of Biological Chemistry2013,,29:1
6Tumor microenvironment-dependent epigenetic imprinting in the vasculature predicts colon cancer outcome显示文摘Dear Editor,Tumor microenvironment(TME)-dependent stromal cell plasticity governs tumor development and therapy response.Tumor endothelial cells(TECs)are a major cellular component in this context[1].In colorectal carcinoma(CRC),the stromal cell-dependent impact of the TME is illustrated by an improved survival depending on an interferon(IFN)-γ-dominated Th1-like TME associated with high T-cell density[2]and suppressed angiogenesis[3,4].Cellular transcriptional memory is reported in cell lines after repeated exposure to IFN-γin vitro[5],suggesting that a Th1-like TME may also exert stable imprinting effects in vivo.Here,we investigated whether TME-dependent transcriptional imprinting in TECs from CRC patients can be exploited to retrieve clinically relevant signatures predicting outcomes.Elisabeth Naschberger Maximilian Fuchs Nicholas Dickel Meik Kunz Bernt Popp Charles Gwellem Anchang Richard Demmler Yanmin Lyu Steffen Uebe Arif Bülent Ekici Carol Immanuel Geppert Arndt Hartmann Christian Flierl Katja Petter Tobias Gass Simon Völkl Michael Scharl Andreas Ramming Claudia Günther Susanne Merkel Vera Simone Schellerer Michael Stürzl 2023Cancer Communications2023,43,11:0
7趋势与传统:南蒂罗尔某新酒店建筑显示文摘数十年来,拥有迷人多样景观和丰富多彩文化的南蒂罗尔一直都是人们徒步旅行度假的首选目的地,这种度假方式在当地非常典型就像大多数德国客人都会穿灯笼裤和格子衬衫一样,这里的酒店设计也很老套——套房里装饰着简单的家具,早餐餐厅里以深色的木镶板贴面、笨重的转角座椅、铸铁灯和阿尔卑斯地区特有的小饰品为主。Claudia Fuchs 周小红(译) 2019建筑细部2019,17,6:0
8感官全体验:餐厅设计的新趋势显示文摘综合风味和地方美食、厨艺展示场所和“游击”餐厅、快餐店和美食餐厅:当代的就餐选择范围极其广泛.在与用餐场所相匹配的环境中为食客们提供了多样的美食体验。人们广泛认同一点:食物的卖相应该吸引眼球,菜品的精美度同空间环境同样重要。一间餐厅的气氛有时能够使就餐的人食欲大增,而在某些情况下则会使人倒胃口。Claudia Fuchs 王艺璇(译) 周荃(审) 2012建筑细部2012,10,3:0
9设计施工中的虚拟现实和增强现实显示文摘SHoP建筑师事务所在布鲁克林的迪卡布尔第九大道住宅楼项目中,正在使用内部开发的应用程序,它具有VR(虚拟现实)和AR(增强现实)功能。这些应用程序在设计和施工过程中的支持作用不仅限于可视化功能。Claudia Fuchs 陈平(译) 王文阳(译) 2020建筑细部2020,18,3:0
10斯特拉斯堡某建筑学院显示文摘自去年九月份以来,建筑学院学生就可以在位于欧洲一个大都市中心的新建筑中学习建筑设计技巧了,该中心位于有几百年发展历史的街区中,从这里到达城市其他地区都很方便。新建筑是一栋高大宽敞的建筑。设有屋顶露台,人们在这里可以欣赏城市的屋顶景观。斯特拉斯堡国立高等建筑学院(ENSAS)自1987年就开始在该地点一处曾为汽车销售中心的20世纪50年代的建筑中办学招生,这里地处历史悠久的中心区域的东部边缘。靠近中心车站。Claudia Fuchs 蒋丽(译) 周荃(审) 2014建筑细部2014,,2:0
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