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	题名	作者	年代	出处	被引量
1	Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed.	Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost	2019	Stroke & Vascular Neurology2019，4，4：	2
2	Aldolase genes of Plasmodium species显示文摘	CLOONAN N FISCHER K CHENG Q	2001	Mol Biochem Parasitol2001，113，2：	1
3	Stevor and rif are Plasmodium falciparum muhicopy gone families which potentially encode variant antigens显示文摘	Cheng Q Cloonan N Fischer K	1998	Mol Biochem Parasitol1998，97，12：	1
4	Stem cell transcriptome profiling via mas- sive-scale mRNA sequencing显示文摘	Cloonan N	2008	Nature Methods2008，5，：	1
5	Stem cell transcriptome profiling via massive-scale mRNA sequencing显示文摘	Cloonan N		0，，7：	1
6	Stem cell transcriptome profiling via massive-scale m RNA sequencing显示文摘	Cloonan N Forrest Alistair R R Kolle G	2008	Nat Methods2008，5，61：	1
7	Hemifa- cial microsomia : from gestation to childhood 显示文摘	WERLER M M STARR J R CLOONAN Y R	2009	J Craniofac Surg2009，20，1：	1
8	Mitochondria:commanders of innate immunity and disease显示文摘	Cloonan S Choi A		0，，01：	1
9	Autophagy: a critical regulator of cellular met'abolism and homeostasis 显示文摘	Ryter SW Cloonan SM Choi AM	2013	Mol Cells2013，36，1：	1
10	Stem cell tran- scriptome profiling via massive-scale mRNA sequencing 显示文摘	CLOONAN N FORREST AR KOLLE G	2011	Nat Methods2011，8，7：	1
11	The emerging importance of autophagy in pulmonary diseases显示文摘	Mizumura K Cloonan S M Haspel J A Choi A M	2012	Chest2012，142，：	1
12	The emerging im- portance of autophagy in pulmonary diseases 显示文摘	Mizumura K Cloonan SM Haspel JA	2012	Chest2012，142，5：	1
13	Tiny RNAs associated with transcription start sites in animals显示文摘	Taft R J Glazov E A Cloonan N	2009	Nature Genetics2009，41，5：	1
14	An organizational climate intervention associated with increased hand washing and decreased nosocomial infections显示文摘	Larson EL Early E Cloonan P	2000	Behav Med2000，26，1：	1
15	Mitophagy- dependent necroptosis contributes to the pathogenesis of COPD显示文摘	Mizumura K Cloonan SM Nakahira K	2014	J Clin Invest2014，124，9：	1
16	Brain natriuretic pep tide predicts functional outcome in ischemic stroke显示文摘	Rost NS Biffi A Cloonan L	2012	Stroke2012，43，2：	1
17	Identification of rup- ture locations in patient-specific abdominal aortic aneurysms using experimental and computational techniques 显示文摘	Doyle B J Cloonan A J Walsh MT	2010	J Biomech2010，43，7：	1
18	a recursive mapping strategy for high-throughput RNA-sequencing data显示文摘	CLOONAN N XU Qinying FAULKNER G J		0，，19：	1
19	Brain natriuretic peptide predicts functional outcome in ischemic stroke显示文摘	Rost NS Biffi A Cloonan L		0，，02：	1
20	Therapeutic potential of heme oxygenase-1/carbon monoxide in lung disease 显示文摘	Constantin M Choi A J Cloonan SM	2012	Int J Hypertens2012，2012，85：	1

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