|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 加氢催化裂解技术用于高演化源岩有机质表征研究显示文摘加氢催化裂解技术作为近年来新发展起来的有机质大分子裂解技术,专门应用于大分子中共价键结合小分子的释放。本研究探索该技术应用于含油气沉积盆地高演化油气源岩原生有机质提取的可能性。以塔里木盆地下古生界油气源岩为例,选取了障壁泻湖相、欠补偿盆地相、闭塞欠补偿陆源海湾相、灰泥丘相等四类典型潜在源岩进行了加氢催化裂解实验,结果表明,加氢催化裂解产物中正构烷烃与甾烷的分布特征与上述源岩相完全吻合,证明加氢催化裂解实验可以有效地提取高演化油气源岩的原生有机质,为下一步实现该技术应用于油气源的对比奠定了基础。 | 孙永革 Will Meredith Colin E Snape 柴平霞 | 2008 | 石油与天然气地质2008，29，2： | 13 |
| 2 | Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?显示文摘AIM To evaluate the association between virulence factor status and antibiotic resistance in Helicobacter pylori(H. pylori)-infected patients in Ireland. METHODS DNA was extracted from antral and corpus biopsies obtained from 165 H. pylori-infected patients. Genotyping for clarithromycin and fluoroquinolone-mediating mutations was performed using the Genotype Helico DR assay. cag A and vac A genotypes were investigated using PCR. RESULTS Primary, secondary and overall resistance rates for clarithromycin were 50.5%(n = 53/105), 78.3%(n = 47/60) and 60.6%(n = 100/165), respectively. Primary, secondary and overall resistance rates for fluoroquinolones were 15.2%(n = 16/105) and 28.3%(n = 17/60) and 20%(n = 33/165), respectively. Resistance to both antibiotics was 12.4%(n = 13/105) in treatment-na?ve patients, 25%(n = 15/60) in those previously treated and 17%(n = 28/165) overall. A cag A-positive genotype was detected in 22.4%(n = 37/165) of patient samples. The dominant vac A genotype was S1/M2 at 44.8%(n = 74/165), followed by S2/M2 at 26.7%(n = 44/165), S1/M1 at 23.6%(n = 39/165) and S2/M1 at 4.8%(n = 8/165). Primary clarithromycin resistance was significantly lower in cag A-positive strains than in cag A-negative strains [32%(n = 8/25) vs 56.3%(n = 45/80); P = 0.03]. Similarly, in patients infected with more virulent H. pylori strains bearing the vac A s1 genotype, primary clarithromycin resistance was significantly lower than in those infected with less virulent strains bearing the vac A s2 genotype, [41%(n = 32/78) vs 77.8%(n = 21/27); P = 0.0001]. No statistically significant association was found between primary fluoroquinolone resistance and virulence factor status.CONCLUSION Genotypic H. pylori clarithromycin resistance is high and cag A-negative strains are dominant in our population. Less virulent(cag A-negative and vac A S2-containing) strains of H. pylori are associated with primary clarithromycin resistance. | Denise E Brennan Colin Dowd Colm O'Morain Deirdre McNamara Sinéad M Smith | 2018 | World Journal of Gastroenterology2018，24，9： | 4 |
| 3 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet2010，，9730： | 3 |
| 4 | CD 64 distinguishes macrophages from dendritic cells in the gut and reveals the T h1‐inducing role of mesenteric lymph node macrophages during colitis显示文摘 | Samira Tamoutounour Sandrine Henri Hugues Lelouard Béatrice de Bovis Colin de Haar C. Janneke van der Woude Andrea M. Woltman Yasmin Reyal Dominique Bonnet Dorine Sichien Calum C. Bain Allan McI. Mowat Caetano Reis e Sousa Lionel F. Poulin Bernard Malisse | 2012 | Eur J Immunol2012，，12： | 2 |
| 5 | Global, regional, and national causes of child mortality in 2008: a systematic analysis显示文摘 | Robert E Black Simon Cousens Hope L Johnson Joy E Lawn Igor Rudan Diego G Bassani Prabhat Jha Harry Campbell Christa Fischer Walker Richard Cibulskis Thomas Eisele Li Liu Colin Mathers | 2010 | The Lancet . 2010 (9730)2010，，： | 2 |
| 6 | Ureteral and muhifocal tumours have worse prognosis than renal pelvic tumours in urothelial carcinoma of the upper urinary tract treated by nephroureterectomy 显示文摘 | OUZZANE A COLIN P XYLINAS E | 2011 | Eur Urol2011，60，6： | 1 |
| 7 | Longitudinal study of children with perinatal braindamage in whom early neurohabilitation was applied: Pre- liminary report显示文摘 | Harmony T Barrera Resendiz J Juarez Colin M E | 2015 | Neurosci Lett2015，611，： | 1 |
| 8 | Vertical distributions of lightning NO, for use in regional and global chemical transport models 显示文摘 | Pickering K E Wang Yansen Too Wei-kuo Price Colin Muller J-F | 1998 | J Geophys Res1998，103，31： | 1 |
| 9 | Murine Denys - Drash syndrome: evi dence of podocyte de - differentiation and systemic mediation of glomerul - oselerosis 显示文摘 | Charles E P Stewart F Colin G M | 2003 | Human Molecular Genetics2003，12，18： | 1 |
| 10 | Seismic travehime analysis for azimuthally anisotropic media:Theory and experiment显示文摘 | Colin M S Daniel A E | 1997 | Geophysics1997，62，5： | 1 |
| 11 | Distribution system planning in focus显示文摘 | Ault Graham W Foote Colin E T Mcdonald James R | 2002 | IEEE Power Engineering Review2002，22，1： | 1 |
| 12 | Recombinant forms of Gerbich blood group antigens:expression and purification显示文摘 | Jaskiewicz E Czerwinski M Colin Y | 2002 | Transfus Clin Biol2002，9，2： | 1 |
| 13 | Ankle arthrodesis using ring exter- nal fixation显示文摘 | Mark E Colin L Samuel W | 2006 | Tech Foot Ankle Surg2006，3，： | 1 |
| 14 | Ureteral and multifocal tumors have worse prognosis than renal pelvic tumors in urothelial carcinoma of the upper urinary tract treated by nephroureterectomy显示文摘 | Ouzzane A Colin P Xylinas E | 2011 | Eur Urol2011，60，： | 1 |
| 15 | Linking growth modeling to timber quality assessment for Norway spruce 显示文摘 | Houllier F Leban J Colin E | 1995 | Forest Ecology and Management1995，74，： | 1 |
| 16 | Isolation of Swine infertility and respiratory syndrome virus(isolate ATCCVR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs显示文摘 | Colines J E Ben field D A Christianson W T | 1992 | J Vet Diagn Invest1992，，4： | 1 |
| 17 | Atlastin1 mutations are frequent in young-onset autosomal dominant spastic paraplegia显示文摘 | Dürr A Camuzat A Colin E | 2004 | Arch Neurol2004，61，12： | 1 |
| 18 | Screening and confirmatory determination of ractopamine residues in calvestreated with growth promoting doses of the β -agonist显示文摘 | Christopher T E Colin S T Cor J A | 1998 | Analyst1998，123，： | 1 |
| 19 | Ureteral and multifocal tumours have worse prognosis than renal pelvic tumours in urothelial carcinoma of the upper urinary tract treated by nephroureterectomy显示文摘 | OUZZANE A COLIN P XYLINAS E | 2011 | Eur Urol2011，60，6： | 1 |
| 20 | Arsenic upregulates MMP-9 and inhibits wound repair in human airway epithelial cel s显示文摘 | Colin E Olsen-Andrew E Liguori-Yue Z | | 0，，02： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员