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| 1 | Nutritional status and nutritional therapy in inflammatory bowel diseases显示文摘Underweight and specific nutrient deficiencies are frequent in adult patients with inflammatory bowel disease(IBD).In addition,a significant number of children with IBD,especially Crohn's disease(CD) have impaired linear growth.Nutrition has an important role in the management of IBD.In adults with CD,enteral nutrition(EN) is effective in inducing clinical remission of IBD,although it is less efficient than corticosteroids.Exclusive EN is an established primary therapy for pediatric CD.Limited data suggests that EN is as efficient as corticosteroids for induction of remission.Additional advantages of nutritional therapy are control of inflammation,mucosal healing,positive benefits to growth and overall nutritional status with minimal adverse effects.The available evidence suggests that supplementary EN may be effective also for maintenance of remission in CD.More studies are needed to confirm these findings.However,EN supplementation could be considered as an alternative or as an adjunct to maintenance drug therapy in CD.EN does not have a primary therapeutic role in ulcerative colitis.Specific compositions of enteral dietselemental diets or diets containing specific components-were not shown to have any advantage over standard polymeric diets and their place in the treatment of CD or UC need further evaluation.Recent theories suggest that diet may be implicated in the etiology of IBD,however there are no proven dietary approaches to reduce the risk of developing IBD. | Corina Hartman Rami Eliakim Raanan Shamir | 2009 | World Journal of Gastroenterology2009，15，21： | 44 |
| 2 | 儿科肠外营养指南(2016版)推荐意见节译显示文摘儿科肠外营养指南英文完整版共分为14篇,刊登在2018年Clinical Nutrition 。除方法篇外,每篇均给出推荐意见列表。在此,我们将方法篇有关证据级别、推荐等级、推荐形式的相关说明以及其余13篇的推荐建议整理成中文版,供国内儿科医护人员参考学习。 | 欧洲儿科胃肠肝病与营养学会 欧洲临床营养与代谢学会 欧洲儿科研究学会 中华医学会肠外肠内营养学分会 Walter Mihatsch K.Joosten J.B.van'Goudoever Alexandre Lapillonne D.Mesotten F.Joehum M.Domellof J.Bronsky S.Kolacek I.Hojsak Susan Hill Arich Riskin Corina Hartman 颜伟慧(译) 吴江(译) 王莹(译) 蔡威(译) | 2018 | 中华儿科杂志2018，56，12： | 18 |
| 3 | Cardiovascular disease risk factor profiles in children with celiac disease on gluten-free diets显示文摘AIM:To describe the cardiovascular disease(CVD)risk factors in a population of children with celiac disease(CD)on a gluten-free diet(GFD).METHODS:This cross-sectional multicenter study was performed at Schneider Children’s Medical Center of Israel(Petach Tiqva,Israel),and San Paolo Hospital(Milan,Italy).We enrolled 114 CD children in serologic remission,who were on a GFD for at least one year.At enrollment,anthropometric measurements,blood lipids and glucose were assessed,and compared to values at diagnosis.The homeostasis model assessment-estimated insulin resistance was calculated as a measure of insulin resistance.RESULTS:Three or more concomitant CVD risk factors[body mass index,waist circumference,low density lipoprotein(LDL)cholesterol,triglycerides,blood pressure and insulin resistance]were identified in 14%of CD subjects on a GFD.The most common CVD risk factors were high fasting triglycerides(34.8%),elevated blood pressure(29.4%),and high concentrations of calculated LDL cholesterol(24.1%).On a GFD,four children(3.5%)had insulin resistance.Fasting insulin and HOMA-IR were significantly higher in the Italian cohort compared to the Israeli cohort(P<0.001).Children on a GFD had an increased prevalence of borderline LDL cholesterol(24%)when compared to values(10%)at diagnosis(P=0.090).Trends towards increases in overweight(from 8.8%to 11.5%)and obesity(from 5.3%to 8.8%)were seen on a GFD.CONCLUSION:This report of insulin resistance and CVD risk factors in celiac children highlights the importance of CVD screening,and the need for dietary counseling targeting CVD prevention. | Lorenzo Norsa Raanan Shamir Noam Zevit Elvira Verduci Corina Hartman Diana Ghisleni Enrica Riva Marcello Giovannini | 2013 | World Journal of Gastroenterology2013，19，34： | 3 |
| 4 | NOD2/CARD15 mutation analysis and genotype-phenotype correlation in Jewish pediatric patients compared with adults with Crohn’s disease显示文摘 | Batia Weiss Raanan Shamir Yoram Bujanover Mati Waterman Corina Hartman Akiva Fradkin Drora Berkowitz Ilana Weintraub Ram Eliakim Amir Karban | 2004 | The Journal of Pediatrics2004，，2： | 2 |
| 5 | Adalimumab Treatment in Children with Refractory Crohn’s Disease显示文摘 | Yoram Rosenbach Corina Hartman Rivka Shapiro Akiva Hirsch Yaron Avitzur Raanan Shamir | 2010 | Digestive Diseases and Sciences2010，，3： | 1 |
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