|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Household air pollution and lung cancer in China:a review of studies in Xuanwei显示文摘Over half of the world's population is exposed to household air pollution from the burning of solid fuels at home. Household air pollution from solid fuel use is a leading risk factor for global disease and remains a major public health problem, especially in low- and mid-income countries. This is a particularly serious problem in China, where many people in rural areas still use coal for household heating and cooking. This review focuses on several decades of research carried out in Xuanwei County, Yunnan Province, where household coal use is a major source of household air pollution and where studies have linked household air pollution exposure to high rates of lung cancer. We conducted a series of case-control and cohort studies in Xuanwei to characterize the lung cancer risk in this population and the factors associated with it. We found lung cancer risk to vary substantially between different coal types, with a higher risk associated with smoky(i.e., bituminous) coal use compared to smokeless(i.e., anthracite) coal use. The installation of a chimney in homes resulted in a substantial reduction in lung cancer incidence and mortality. Overall, our research underscores the need among existing coal users to improve ventilation, use the least toxic fuel, and eventually move toward the use of cleaner fuels, such as gas and electricity. | Wei Jie Seow Wei Hu Roel Vermeulen H.Dean Hosgood III George S.Downward Robert S.Chapman Xingzhou He Bryan A.Bassig Christopher Kim Cuiju Wen Nathaniel Rothman Qing Lan | 2014 | Chinese Journal of Cancer2014，33，10： | 15 |
| 2 | Stable chloroplast transformation of immature scutella and inflorescences in wheat (Triticum aestivum L.)显示文摘在小麦的叶绿体转变被 scutella 的轰炸分别地从不成熟的胚胎和不成熟的开花期完成。小麦叶绿体地点特定的表示向量, pBAGNRK,被放包含新霉素 phosphotransferase II (nptII ) 和绿色的一个表示盒子构造荧光灯蛋白质(gfp ) 作为选择和记者基因,分别地在在小麦的 atpB 和 rbcL 之间的 intergenic 分隔符叶绿体染色体。在 plastome 的 gfp 基因的集成被聚合酶链反应(PCR ) 识别分析并且作为一根探针的用 gfp 基因的南部的弄污。GFP 蛋白质的表示被西方的污点检验。三积极 transformants 被获得, atpB 和 rbcL (指向的地点) 的部分碎片的南部的污点探查证实他们之一是 homoplasmic。GFP 荧光的稳定的表示被共焦的显微镜学从 T1 子孙幼苗在叶纸巾证实。gfp 基因的 PCR 分析也在 T1 子孙证实了 transgene 的继承。这些结果加强小麦叶绿体转变的可行性并且也通过叶绿体转变在小麦为重要农学的特点的介绍给一个新奇方法。 | Cuiju Cui FeiSong Yi Tan Xuan Zhou Wen Zhao Fengyun Ma Yunyi Liu Javeed Hussain Yuesheng Wang Guangxiao Yang Guangyuan He | 2011 | Acta Biochimica et Biophysica Sinica2011，43，4： | 10 |
| 3 | Characterization of Genome-Wide Microsatellites of Saccharina japonica Based on a Preliminary Assembly of Illumina Sequencing Reads显示文摘Microsatellites or simple sequence repeats(SSR) function widely and locate dependently in genome. However, their characteristics are often ignored due to the lack of genomic sequences of most species. Kelp(Saccharina japonica), a brown macroalga, is extensively cultured in China. In this study, the genome of S. japonica was surveyed using an Illumina sequencing platform, and its microsatellites were characterized. The preliminarily assembled genome was 469.4 Mb in size, with a scaffold N_(50) of 20529 bp. Among the 128370 identified microsatellites, 90671, 25726 and 11973 were found in intergenic regions, introns and exons, averaging 339.3, 178.8 and 205.4 microsatellites per Mb, respectively. These microsatellites distributed unevenly in S. japonica genome. Mononucleotide motifs were the most abundant in the genome, while trinucleotide ones were the most prevalent in exons. The microsatellite abundance decreased significantly with the increase of motif repeat numbers, and the microsatellites with a small number of repeats accounted for a higher proportion of the exons than those of the intergenic regions and introns. C/G-rich motifs were more common in exons than in intergenic regions and introns. These characteristics of microsatellites in S. japonica genome may associate with their functions, and ultimately their adaptation and evolution. Among the 120140 pairs of designed microsatellite primers, approximately 75% were predicted to be able to amplify S. japonica DNA. These microsatellite markers will be extremely useful for the genetic breeding and population evolution studies of kelp. | ZHANG Linan PENG Jie LI Xiaojie CUI Cuiju SUN Juan YANG Guanpin | 2016 | Journal of Ocean University of China2016，15，3： | 2 |
| 4 | Hypoxia Attenuates the Expression of E-Cadherin via Up-Regulation of SNAIL in Ovarian Carcinoma Cells显示文摘 | Tsutomu Imai Akiko Horiuchi Cuiju Wang Kenji Oka Satoshi Ohira Toshio Nikaido Ikuo Konishi | 2003 | The American Journal of Pathology2003，，4： | 2 |
| 5 | The association of interleukin-16 gene polymorphisms with IL-16 serum levels and risk of nasopharyngeal carcinoma in a Chinese population显示文摘 | Xue Qin Qiliu Peng Xiaoxia Lao Zhiping Chen Yu Lu Xianjun Lao Cuiju Mo Jingzhe Sui Junrong Wu Limin Zhai Shi Yang Shan Li Jinmin Zhao | 2014 | Tumor Biology2014，，3： | 2 |
| 6 | Hypoxia attenuates the expression of E - cadhefin via up - regulation of SNAIL in ovarian carcinoma cells 显示文摘 | Tsutomu II Akiko H Cuiju W | 2003 | Am J Pathol2003，163，4： | 1 |
| 7 | Hypoxia attenuates the expression of E-cadherin via up-regulation of Snail in ovarian carcinoma cells显示文摘 | Tsutomu Imai Akiko Horiuchi Cuiju Wang | 2003 | Am J Pathol2003，163，4： | 1 |
| 8 | Rhodaelectro-Catalyzed C–H and C–C Activation显示文摘Rhodium(III)catalysis has set the stage for a plethora of oxidative C–H functionalizations over the last decade,which have predominantly employed stoichiometric amounts of toxic and expensive metal oxidants,such as silver(I)salts.In the meantime,electrosynthesis has emerged as an increasingly viable alternative for expensive and toxic oxidants.Recently,significant momentum has been achieved with the merger of electrocatalysis with organometallic C–H activation.However,user-friendly and robust rhodaelectro-catalysis has until very recently proven elusive for oxidative C–H activations.This minireview highlights the current knowledge and recent advances of electrooxidation in rhodium-catalyzed C–H or C–C activations,with a topical focus on contributions from the Ackermann group through July 2020. | Youai Qiu Cuiju Zhu Maximilian Stangier Julia Struwe Lutz Ackermann | 2021 | CCS Chemistry2021，3，2： | 1 |
| 9 | A Rabbit D, Eye Model Induced by Topical Medication of a Preservative Benzalkonium Chloride 显示文摘 | Cuiju Xiong Dong Chen Jingbo Liu | 2008 | Invest Ophthalmol V is Sci2008，49，5： | 1 |
| 10 | Mitochondrial DNA haplogroup N is associated good outcome of gastric cancer显示文摘 | Cuiju Wang Yingnan Wang Huiying Wang Ruixing Zhang Zhanjun Guo | 2014 | Tumor Biology2014，，12： | 1 |
| 11 | Different mechanisms underlying divergent responses of autotrophic and heterotrophic respiration to long-term throughfall reduction in a warm-temperate oak forest显示文摘Background:There are many studies on disentangling the responses of autotrophic(AR)and heterotrophic(HR)respiration components of soil respiration(SR)to long-term drought,but few studies have focused on the mechanisms underlying its responses.Methods:To explore the impact of prolonged drought on AR and HR,we conducted the 2-year measurements on soil CO_(2) effluxes in the 7th and 8th year of manipulated throughfall reduction(TFR)in a warm-temperate oak forest.Results:Our results showed long-term TFR decreased HR,which was positively related to bacterial richness.More importantly,some bacterial taxa such as Novosphingobium and norank Acidimicrobiia,and fungal Leptobacillium were identified as major drivers of HR.In contrast,long-term TFR increased AR due to the increased fine root biomass and production.The increased AR accompanied by decreased HR appeared to counteract each other,and subsequently resulted in the unchanged SR under the TFR.Conclusions:Our study shows that HR and AR respond in the opposite directions to long-term TFR.Soil microorganisms and fine roots account for the respective mechanisms underlying the divergent responses of HR and AR to long-term TFR.This highlights the contrasting responses of AR and HR to prolonged drought should be taken into account when predicting soil CO_(2) effluxes under future droughts. | Jinglei Zhang Shirong Liu Cuiju Liu Hui Wang Junwei Luan Xiaojing Liu Xinwei Guoand Baoliang Niu | 2021 | Forest Ecosystems2021，8，3： | 1 |
| 12 | Genetic variation in C12orf51 is associated with prognosis of intestinal-type gastric cancer in a Chinese population显示文摘 | Gang Zhang Dongying Gu Qinghong Zhao Haiyan Chu Zhi Xu Meilin Wang Cuiju Tang Dongmei Wu Na Tong Weida Gong Jianwei Zhou Yong Xu Zhengdong Zhang Jinfei Chen | 2014 | Biomedicine & Pharmacotherapy2014，，： | 1 |
| 13 | A polymorphism at the miR-502 binding site in the 3′ untranslated region of the SET8 gene is associated with the risk of epithelial ovarian cancer显示文摘 | Cuiju Wang Zhanjun Guo Chensi Wu Yan Li Shan Kang | 2012 | Cancer Genetics (-)2012，，7： | 1 |
| 14 | Effects of p38 MAPK inhibitor on the rat pain behavior and proinflammatory cytokines in a metastatic bone cancer pain model显示文摘Objective:To observe the effects of p38 mitogen activated protein kinase(MAPK) inhibitor SB203580 by intra-thecal injection on the pain behavior and the spinal proinflammatory cytokines in a rat model of bone cancer pain induced by breast cancer cells. Methods:Eleven rats were used to establish the models of bone cancer pain,six rats were treated by intrathecal SB203580 injection,and the other 5 were as the controls. The paw withdrawal latency(PWL),histology and the spinal levels of IL-1β and TNF-α were detected. Results:All the 11 rats presented evident bone destruction and thermal hyperalgesia after intra-tibial injection of breast cancer cells. No effect of SB203580 on the bone destruction was observed. However,following intrathecal injection of SB203580,the left PWLs(12.12 ± 1.26 s at 16 days and 12.99 ± 1.65 s at 19 days) were significant higher than that of controls(9.05 ± 1.08 s at 16 days and 8.55 ± 1.60 s at 19 days),P < 0.05. Meanwhile,intrathecal injection of SB203580 evidently reduced the levels of spinal IL-1β and TNF-α. Conclusion:Intrathecal injection of SB203580 in a rat model of bone cancer pain cannot prevent the tibial destruction but significantly depress the thermalgia sensitivity,which might result from inhibiting intracellular p38 MAPK signaling transduction,and thereby reducing the release of the proinflammatory cytokines. | Cuiju Tang Shiying Yu Min Zhang Rui Jiang Na Li Huiting Xu | 2008 | The Chinese-German Journal of Clinical Oncology2008，7，3： | 0 |
| 15 | Copper-catalyzed asymmetric propargylic substitution of anthrones and propargylic esters显示文摘Anthrones are key structural motifs in many natural products, bioactive compounds and pharmaceutical chemicals. Earth-abundant-metal-catalyzed asymmetric functionalization of anthrones has not proved to be viable. Herein, we disclosed a highly enantioselective propargylic substitution of anthrones with propargylic esters using copper salts with chiral N, N, P-ligand. This strategy is amenable to a broad range of substrates, uses readily available starting materials, provides excellent yields with remarkable enantioselectivity under mild conditions, and enables attractive products diversification routes. | Zhiheng Li Danran Li Huaming Xiang Jian Huang Yinuo Zheng Cuiju Zhu Xiuling Cui Chao Pi Hao Xu | 2022 | Chinese Chemical Letters2022，33，2： | 0 |
| 16 | Multi-year throughfall reduction enhanced the growth and non-structural carbohydrate storage of roots at the expenses of above-ground growth in a warm-temperate natural oak forest显示文摘The more frequent occurrence and severer drought events resulting from climate change are increasingly affecting the physiological performance of trees and ecosystem carbon sequestration in many regions of the world.However,our understanding of the mechanisms underlying the responses and adaption of forest trees to prolonged and multi-year drought is still limited.To address this problem,we conducted a long-term manipulative throughfall reduction(TFR,reduction of natural throughfall by 50%–70%during growing seasons)experiment in a natural oriental white oak(Quercus aliena var.acuteserrata Maxim.)forest under warm-temperate climate.After seven years of continuous TFR treatment,the aboveground growth in Q.aliena var.acuteserrata started to decline.Compared with the control plots,trees in the TFR treatment significantly reduced growth increments of stems(14.2%)and leaf area index(6.8%).The rate of net photosynthesis appeared to be more susceptible to changes in soil water in trees subjected to the TFR than in the control.The TFR-treated trees allocated significantly more photosynthates to belowground,leading to enhanced growth and nonstructural carbohydrates(NSC)storage in roots.The 7-year continuous TFR treatment increased the biomass,the production and the NSC concentration in the fine roots by 53.6%,153.6%and 9.6%,respectively.There were clear trade-offs between the aboveground growth and the fine root biomass and NSC storage in Q.aliena var.acuteserrata trees in response to the multi-year TFR treatment.A negative correlation between the fine root NSC concentration and soil water suggested a strategy of preferential C storage over growth when soil water became deficient;the stored NSC during water limitation would then help promote root growth when drought stress is released.Our findings demonstrate the warm-temperate oak forest adopted a more conservative NSC use strategy in response to long-term drought stress,with enhanced root growth and NSC storage at the expenses of above-ground growth to mitigate climate changeinduced drought. | Cuiju Liu Zhicheng Chen Shirong Liu Kunfang Cao Baoliang Niu Xiaojing Liu Xiaomin Gao | 2023 | Forest Ecosystems2023，10，3： | 0 |
| 17 | Remote copper-catalyzed enantioselective substitution of yne-thiophene carbonates显示文摘Here,we describe a strategy for the copper-catalyzed asymmetric heteroarylation of yne-thiophene carbonates with indoles via remote substitution.The key to the success of this strategy lies in the design of the alkynyl group at the ortho-position of the heterocycle thiophene,enabling the formation of a triarylmethane moiety via very remote substitution.Thus,the concept of remote copper-catalyzed asymmetric transformation extends not only to yne-allylic esters but also to yne-aryl esters.The reaction readily provides a diverse array of chiral triarylmethanes with high efficiency,enantioselectivity,and excellent functional group compatibility.Moreover,facile follow-up transformations underscore their potential utility in the synthesis of various enantioenriched building blocks.Preliminary mechanistic studies support the plausibility of the remote substitution pathway. | Hao-Dong Qian Xiang Li Tingrui Yin Wei-Feng Qian Chunhui Zhao Cuiju Zhu Hao Xu | 2024 | Science China Chemistry2024，67，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员