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| 1 | Laser beam induced current microscopy and photocurrent mapping for junction characterization of infrared photodetectors显示文摘For non-destructive optical characterization, laser beam induced current(LBIC) microscopy has been developed into as a quantitative tool to examine individual photodiodes within a large pixel array. Two-dimensional LBIC microscopy, also generally called photocurrent mapping(PC mapping), can provide spatially resolved information about local electrical properties and p-n junction formation in photovoltaic infrared(including visible light) photodetectors from which it is possible to extract material and device parameters such as junction area, junction depth, diffusion length, leakage current position and minority carrier diffusion length etc. This paper presents a comprehensive review of research background, operating principle, fundamental issues, and applications of LBIC or PC mapping. | QIU WeiCheng HU WeiDa | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，2： | 15 |
| 2 | Ultrafast and broadband photodetectors based on a perovskite/organic bulk heterojunction for large-dynamic-range imaging显示文摘Organic-inorganic hybrid perovskite(OIHP)photodetectors that simultaneously achieve an ultrafast response and high sensitivity in the near-infrared(NIR)region are prerequisites for expanding current monitoring,imaging,and optical communication capbilities.Herein,we demonstrate photodetectors constructed by OIHP and an organic bulk heterojunction(BHJ)consisting of a low-bandgap nonfullerene and polymer,which achieve broadband response spectra up to 1μm with a highest external quantum efficiency of approximately 54%at 850 nm,an ultrafast response speed of 5.6 ns and a linear dynamic range(LDR)of 191 dB.High sensitivity,ultrafast speed and a large LDR are preeminent prerequisites for the practical application of photodetectors.Encouragingly,due to the high-dynamicrange imaging capacity,high-quality visible-NIR actual imaging is achieved by employing the OIHP photodetectors.We believe that state-of-the-art OIHP photodetectors can accelerate the translation of solution-processed photodetector applications from the laboratory to the imaging market. | Chenglong Li Hailu Wang Fang Wang Tengfei Li Mengjian Xu Hao Wang Zhen Wang Xiaowei Zhan Weida Hu Liang Shen | 2020 | Light(Science & Applications)2020，9，1： | 13 |
| 3 | Synthetical Efficiency-based Optimization for the Power Distribution of Power-split Hybrid Electric Vehicles显示文摘Now the optimization strategies for power distribution are researched widely,and most of them are aiming to the optimal fuel economy and the driving cycle must be preknown.Thus if the actual driving condition deviates from the scheduled driving cycle,the effect of optimal results will be declined greatly.Therefore,the instantaneous optimization strategy carried out on-line is studied in this paper.The power split path and the transmission efficiency are analyzed based on a special power-split scheme and the efficiency models of the power transmitting components are established.The synthetical efficiency optimization model is established for enhancing the transmission efficiency and the fuel economy.The identification of the synthetical efficiency as the optimization objective and the constrain group are discussed emphatically.The optimization is calculated by the adaptive simulated annealing(ASA)algorithm and realized on-line by the radial basis function(RBF)-based similar models.The optimization for power distribution of the hybrid vehicle in an actual driving condition is carried out and the road test results are presented.The test results indicate that the synthetical efficiency optimization method can enhance the transmission efficiency and the fuel economy of the power-split hybrid electric vehicle(HEV)observably.Compared to the rules-based strategy the optimization strategy is optimal and achieves the approximate global optimization solution for the power distribution.The synthetical efficiency optimization solved by ASA algorithm can give attentions to both optimization quality and calculation efficiency,thus it has good application foreground for the power distribution of power-split HEV. | WANG Weida HAN Lijin XIANG Changle MA Yue LIU Hui | 2014 | Chinese Journal of Mechanical Engineering2014，27，1： | 12 |
| 4 | Thermoluminescence dating of the ancient Chinese porcelain using a regression method of saturation exponential in pre-dose technique显示文摘This paper studies the thermoluminescence (TL) dating of the ancient por- celain using a regression method of saturation exponential in the pre-dose technique. The experimental results show that the measured errors are 15% (±1σ) for the paleodose and 17% (±1σ) for the annual dose respectively, and the TL age error is 23% (±1σ) in this method. The larger Chinese porcelains from the museum and the nation-wide collectors have been dated by this method. The results show that the certainty about the authenticity testing is larger than 95%, and the measurable porcelains make up about 95% of the por- celain dated. It is very successful in discrimination for the imitations of ancient Chinese porcelains. This paper describes the measured principle and method for the paleodose of porcelains. The TL ages are dated by this method for the 39 shards and porcelains from past dynasties of China and the detailed data in the measurement are reported. | WANG Weida XIA Junding ZHOU Zhixin | 2006 | Science China(Technological Sciences)2006，49，2： | 11 |
| 5 | MPC-based energy management with adaptive Markov-chain prediction for a dual-mode hybrid electric vehicle显示文摘The and energy to management strategy battery is state an important part of a hybrid electrical vehicle design.It is used to improve various fuel economy sustain a proper of charge an by controlling control the power components is while satisfying to constraints and driving demands.However,achieving optimal and performance challenging due the nonlinearities of the hybrid powertrain,conflicting vehicle the time varying constraints,the dilemma capable in which controller control complexity and real-time capability are generally objectives.In this paper,a of real-time cascaded complies strategy is proposed for a dual-mode hybrid electric that considers controller based nonlinearities based the system model and with all time-varying with constraints.sampling The strategy consists of a supervisory controller on a non-linear predictive control short(MPC)sampling a long time with future strategy interval and a coordinating on linear model predictive based control with a time interval to deal different load dynamics of the system.The Additionally,a novel data methodology using adaptive Markov chains to predict demand is introduced.predictive future information is used to improve controller cycles performance.conducted.The The proposed is implemented validity on a real test-bed approach and experimental trials using economy unknown is driving are results other demonstrate the of the proposed and show that fuel significantly improved compared with methods. | XIANG ChangLe DING Feng WANG WeiDa HE Wei QI YunLong | 2017 | Science China(Technological Sciences)2017，60，5： | 11 |
| 6 | Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma显示文摘Glioblastoma(GBM)is an incurable and highly heterogeneous brain tumor,originating from human neural stem/progenitor cells(hNSCs/hNPCs)years ahead of diagnosis.Despite extensive efforts to characterize hNSCs and end-stage GBM at bulk and single-cell levels,the de novo gliomagenic path from hNSCs is largely unknown due to technical difficulties in early-stage sampling and preclinical modeling.Here,we established two highly penetrant hNSC-derived malignant glioma models,which resemble the histopathology and transcriptional heterogeneity of human GBM.Integrating time-series analyses of whole-exome sequencing,bulk and single-cell RNA-seq,we reconstructed gliomagenic trajectories,and identified a persistent NSC-like population at all stages of tumorigenesis.Through trajectory analyses and lineage tracing,we showed that tumor progression is primarily driven by multi-step transcriptional reprogramming and fate-switches in the NSC-like cells,which sequentially generate malignant heterogeneity and induce tumor phenotype transitions.We further uncovered stage-specific oncogenic cascades,and among the candidate genes we functionally validated C1QL1 as a new glioma-promoting factor.Importantly,the neurogenic-to-gliogenic switch in NSC-like cells marks an early stage characterized by a burst of oncogenic alterations,during which transient AP-1 inhibition is sufficient to inhibit gliomagenesis.Together,our results reveal previously undercharacterized molecular dynamics and fate choices driving de novo gliomagenesis from hNSCs,and provide a blueprint for potential early-stage treatment/diagnosis for GBM. | Xiaofei Wang Ran Zhou Yanzhen Xiong Lingling Zhou Xiang Yan Manli Wang Fan Li Chuanxing Xie Yiming Zhang Zongyao Huang Chaoqiong Ding Kaidou Shi Weida Li Yu Liu Zhongwei Cao Zhen-Ning Zhang Shengtao Zhou Chong Chen Yan Zhang Lu Chen Yuan Wang | 2021 | Cell Research2021，31，6： | 8 |
| 7 | Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine显示文摘Realizing personalized medicine requires integrating diverse data types with bioinformatics.The most vital data are genomic information for individuals that are from advanced next-generation sequencing(NGS) technologies at present.The technologies continue to advance in terms of both decreasing cost and sequencing speed with concomitant increase in the amount and complexity of the data.The prodigious data together with the requisite computational pipelines for data analysis and interpretation are stressors to IT infrastructure and the scientists conducting the work alike.Bioinformatics is increasingly becoming the rate-limiting step with numerous challenges to be overcome for translating NGS data for personalized medicine.We review some key bioinformatics tasks,issues,and challenges in contexts of IT requirements,data quality,analysis tools and pipelines,and validation of biomarkers. | HONG HuiXiao ZHANG WenQian SHEN Jie SU ZhenQiang NING BaiTang HAN Tao PERKINS Roger SHI LeMing TONG WeiDa | 2013 | Science China(Life Sciences)2013，56，2： | 7 |
| 8 | Laser direct writing and characterizations of flexible piezoresistive sensors with microstructures显示文摘Functional materials with high viscosity and solid materials have received more and more attentions in flexible pressure sensors,which are inadequate in the most used molding method.Herein,laser direct writing(LDW)method is proposed to fabricate flexible piezoresistive sensors with microstructures on PDMS/MWCNTs composites with an 8%MWCNTs mass fraction.By controlling laser energy,microstructures with different geometries can be obtained,which significantly impacts the performances of the sensors.Subsequently,curved microcones with excellent performance are fabricated under parameters of f=40 kHz and v=150 mm·s^(-1).The sensor exhibits continuous multi-linear sensitivity,ultrahigh original sensitivity of 21.80%kPa^(-1),wide detection range of over 20 kPa,response/recovery time of~100 ms and good cycle stability for more than 1000 times.Besides,obvious resistance variation can be observed when tiny pressure(a peanut of 30 Pa)is applied.Finally,the flexible piezoresistive sensor can be applied for LED brightness controlling,pulse detection and voice recognition. | Chenying Zhang Wei Zhou Da Geng Cheng Bai Weida Li Songyue Chen Tao Luo Lifeng Qin Yu Xie | 2021 | Opto-Electronic Advances2021，4，4： | 7 |
| 9 | Effect of ZrO_2 Content on the Properties of Diamond Grinding Wheel Vitrified Bond显示文摘The effect of ZrO2 content on the performance of vitrified bond was discussed. The results showed that when the ZrO2 content was less than 2 mol%, Zr4+ could enter into the glassy network as mending nets and agglomeration composition. In this case, with the increasing of ZrO2, the vitrified bond's bending strength increased and the expansion coefficient decreased. It was also found that the wetting angle between the vitrified bond and diamond got small because Zr4+ was enriched on diamond surface. When ZrO2 content was more than 2 mol%, a part of ZrO2 existing in vitrified bond as ZrO2 particles played the role in nucleating agents and promoting the separation of spodumene. When ZrO2 content was 3 mol%, the bending strength of the vitrified bond reached its maximum of 128 MPa and the wetting angle with the diamond reached its minimum of 37.6°. | 刘小磐 QIAO Ang WAN Long HU Weida SONG Dongdong LI Zheng YIN Zhongjie 潘瑞琨 | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，1： | 7 |
| 10 | Roles of fishing and climate change in long-term fish species succession and population dynamics in the outer Beibu Gulf,South China Sea显示文摘A prevailing,controversial hypothesis is that fishing pressure has played a greater role than climatic and environmental drivers,in changing fish species succession and biomass fluctuation in the South China Sea(SCS).Based on otter trawl survey data from 1959 to 2010 in the outer Beibu Gulf(OBG),northern SCS,large seasonal and interannual variation is reported for fish species composition,the proportional abundances of dominant taxa,and fish biomass.Generalized additive models are developed to quantify relationships between fish biomass and the external factors of fishing pressure and climate change.Fishing pressure proved to be the main driver of sharp declines in demersal fish stocks,with high-value species being replaced by low-value ones over time.Abrupt decreases in fish biomass during the years of 1993 and 1998 correspond to El Nino events,with climate change possibly the main driver of proportional representation of pelagic species in fisheries trawl catch.The need to differentiate impacts of fishing and environmental drivers on fish species with different life history strategies is stressed to better understand fish community dynamics. | Xuehui Wang Yongsong Qiu Feiyan Du Weida Liu Dianrong Sun Xiao Chen Weiwen Yuan Yong Chen | 2019 | Acta Oceanologica Sinica2019，38，10： | 6 |
| 11 | Analysis Method and Principle of Dual-mode Electro-mechanical Variable Transmission Program显示文摘Automotive industry,as an important pillar of the national economy,has been rapidly developing in recent years.But proplems such as energy comsumption and environmental pollution are posed at the same time.Electro-mechanical variable transmission system is considered one of avilable workarounds.It is brought forward a kind of design methods of dual-mode electro-mechanical variable transmission system rotational speed characteristics and dual-mode drive diagrams.With the motor operating behavior of running in four quadrants and the speed characteristics of the simple internal and external meshing single planetary gear train,four kinds of dual-mode electro-mechanical transmission system scheme are designed.And the velocity,torque and power characteristics of one of the programs are analyzed.The magnitude of the electric split-flow power is an important factor which influences the system performance,so in the parameters matching design,it needs to reduce the power needs under the first mode of the motor.The motor,output rotational speed range and the position of the mode switching point have relationships with the characteristics design of the planetary gear set.The analysis method is to provide a reference for hybrid vehicles' design.As the involved rotational speed and torque relationships are the natural contact of every part of transmission system,a theory basis of system program and performance analysis is provided. | LI Hongcai YAN Qingdong XIANG Changle WANG Weida | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 6 |
| 12 | Primary structure of helix C to helix G of a new retinal protein in H.sp.xz515显示文摘The gene fragment encoding the retinal protein from helix C to helix G in a new strain of halobacteria, H.sp.xz515 has been amplified by PCR method. The nucleotide sequence of this fragment has been determined. The deduced amino acid sequence has been compared with halobium br and other two br-like proteins, ar-1 and ar-2. Results show that those amino acid residues in br, essential for proton pumping and binding to retinal, are conserved. The residue M145 in br may be important for isomerization reaction of retinal. | Hui Wang Shuxuan Zhan Qingan Sun Deqiang Xu Wei Zhao Weida Huang Qingguo Li | 2000 | Chinese Science Bulletin2000，45，12： | 5 |
| 13 | Medical therapy for clinical benign prostatic hyperplasia:α1 Antagonists,5α reductase inhibitors and their combination显示文摘Medical therapy for clinical benign prostatic hyperplasia(BPH)has advanced significantly in the last 2 decades.Many new a1 antagonists and 5a reductase inhibitors(5ARi)are now commercially available.The practicing urologist must decide on the most appropriate medication for his patients,taking into consideration various factors like efficacy,dosing regime,adverse effects,cost,patient’s socioeconomic background,expectations,drug availability and his own clinical experience.The use of combination therapy added further to the complexity in clinical judgment when prescribing.We highlight some of the key points in prescribing a1 antagonists,5ARi and their combination,based on our viewpoints and experience as urologists in an Asian clinical setting. | Cheuk Fan Shum Weida Lau Chang Peng Colin Teo | 2017 | Asian Journal of Urology2017，4，3： | 4 |
| 14 | Progress and challenges in blocked impurity band infrared detectors for space-based astronomy显示文摘Astronomical detection at infrared wavelengths is crucial in astrophysics due to the critical information in this wavelength range.Blocked impurity band(BIB) infrared detectors are desirable for space-based astronomical observation due to their broad response range, low dark currents, high quantum efficiencies, and excellent radiation resistance. In this review, typical BIB device structures and device physics development are first introduced. Subsequently, we discuss progress in Si-based BIB detectors with different doping types and emphasize their applications in space-based infrared detection. Additionally, we discuss recent efforts on pixel performance optimization, response extension, and higher operating temperature devices. Finally,we conclude by proposing the challenges and perspectives of BIB detectors with improved detection performances. | Yunlong Xiao He Zhu Ke Deng Peng Wang Qing Li Ting He Tao Zhang Jinshui Miao Ning Li Wei Lu Ning Dai Weida Hu | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 4 |
| 15 | Pristine PN junction toward atomic layer devices显示文摘In semiconductor manufacturing,PN junction is formed by introducing dopants to activate neighboring electron and hole conductance.To avoid structural distortion and failure,it generally requires the foreign dopants localize in the designated micro-areas.This,however,is challenging due to an inevitable interdiffusion process.Here we report a brand-new junction architecture,called'layer PN junction',that might break through such limit and help redefine the semiconductor device architecture.Different from all existing semiconductors,we find that a variety of van der Waals materials are doping themselves from n-to p-type conductance with an increasing/decreasing layer-number.It means the capability of constructing homogeneous PN junctions in monolayers'dimension/precision,with record high rectification-ratio(>10^(5))and low cut-off current(<1 pA).More importantly,it spawns intriguing functionalities,like gate-switchable-rectification and noise-signal decoupled avalanching.Findings disclosed here might open up a path to develop novel nanodevice applications,where the geometrical size becomes the only critical factor in tuning charge-carrier distribution and thus functionality. | Hui Xia Man Luo Wenjing Wang Hailu Wang Tianxin Li Zhen Wang Hangyu Xu Yue Chen Yong Zhou Fang Wang Runzhang Xie Peng Wang Weida Hu Wei Lu | 2022 | Light(Science & Applications)2022，11，7： | 4 |
| 16 | Dynamic Stability Analysis of Wedge in Rock Slope Based on Kinetic Vector Method显示文摘A new method(kinetic vector method, KVM) is presented for analyzing the dynamic stability of wedge in rock slope. The dynamic analysis is carried out based on three dimensional distinct element code(3DEC), and the kinetic inertial force of the wedge under seismic loading can be obtained via calculating the net vectorial nodal force of the finite difference grid. Then, the factor of safety(FOS) of the wedge can be calculated based on limit equilibrium method(LEM) at each dynamic analysis step, therefore time series of the FOS for whole earthquake process can be obtained. For the purpose of evaluating the entire dynamic stability of the wedge, dynamic factor of safety(DFOS) is proposed and defined as a numerical value corresponding with a given rate of probability guarantee based on reliability theory. Consequently, the KVM inherits the merits of the LEM and also has fully nonlinear dynamic analysis capabilities, and the feasibility and correctness of the KVM are tested by an example given by Hoek and Bray(1981). Finally, a rock slope case in Wenchuan Earthquake regions of China is presented to verify the engineering practicability of the KVM, and the results matched the actual situation well. | Weida Ni Huiming Tang Xiao Liu Rui Yong Zongxing Zou | 2014 | Journal of Earth Science2014，25，4： | 4 |
| 17 | Oral vaccination of mice against rodent malaria with recombinant Lactococcus lactis expressing MSP-1_(19)显示文摘瞄准:构造 recombinant Lactococcus 乳酸作为对疟疾的口头的交货种痘。方法:变形体 yoelii 265-BY 的 MSP1 (MSP-1 (19 )) 的 C 终端 19-ku 碎片在 L 被表示。乳酸是并且 recombinant L。乳酸是予 BALB/c 和 C57BL/6 老鼠口头上地被以。在在 4 wk 以内的七间隔种痘以后,老鼠与 P 被质问。红细胞舞台的 yoelii 265-BY 寄生虫。recombinant L 的保护的功效。乳酸被评估。结果:分别地,在为 BALB/c 和 C57BL/6 鼠标的实验组的一般水准的山峰 parasitemias 是 0.8+/-0.4% 和 20.8+/-26.5% ,他们的控制组的那些分别地是 12.0+/-0.8% 和 60.8+/-9.6% 。任何一个都没在实验期间死于在试验性的组和控制组的 BALB/c 老鼠。然而,在控制组的所有 C57BL/6 鼠标在 23 d 和熬过很好的所有种牛痘的鼠标以内死了。结论:结果暗示 recombinant L 的潜力。乳酸作为对疟疾的口头的交货种痘。 | Zhi-Hong Zhang Pei-Hong Jiang Ning-Jun Li Mi Shi Weida Huang | 2005 | World Journal of Gastroenterology2005，11，44： | 4 |
| 18 | Wafer-scale arrayed p-n junctions based on few-layer epitaxial GaTe显示文摘二维(2D ) 材料吸引了实质的注意在电子并且有灵活、透明、高度悦耳的优异优点的 optoelectronic 应用。当时,无差距的 graphene 展出极端宽带、快的 photoresponse 半导体的瞬间 2 和门高展出的 2D 敏感和悦耳的 responsivity 到可见的光。然而,设备收益和重覆性打电话让进一步的改进完成大规模一致性。这里,我们与 28.4 厘米 2/(V0 的高洞活动性报导晶片规模门的 layer-by-layer | Xiang Yuan Lei Tang Peng Wang Zhigang Chen Yichao Zou Xiaofeng Su Cheng Zhang Yanwen Liu Weiyi Wang Cong Liu Fansheng Chen Jin Zou Peng Zhou Weida Hu Faxian Xiu | 2015 | Nano Research2015，8，10： | 4 |
| 19 | Is it safe to perform operation for colorectal malignancy in Chinese patients without DVT prophylaxis? An 8-year experience from a regional hospital in Hong Kong显示文摘背景 Colorectal 外科为手术后的深静脉血栓(DVT ) 和肺的栓塞被认为是高风险外科之一。在为 malignancy.Methods 数据的 colorectal 外科从从 2000 ~ 2008 的 colorectal 恶意的未来的数据库是镇定的以后,这研究瞄准了调查静脉的 thromboembolism (VTE ) 的发生。1421 colorectal 的一个总数(开并且 laparoscopic ) 没有 DVT prophylaxis.Results,手术仅仅为 colorectal 恶意被动七个病人(0.5%) 开发了征兆的 DVT,没有死亡,他们之一有肺的栓塞的复杂并发症。然而,为 colorectal 恶意的开的操作作为 DVT 的可能的风险因素被识别风险因素喜欢起作用的时间,低前面的切除术,性,在 colorectal 操作用我们的地区的汉语是低的,没有 DVT 预防,为恶意动 colorectal 手术可能是安全的以后,年龄等等不是静脉的 thromboembolism 的 identified.Conclusion 风险。 | Day Weida Lau Ying Yu Patrick Yip Wai Chun Andrew | 2010 | Chinese Medical Journal2010，，15： | 3 |
| 20 | Tinea faciei in a newborn due toTrichophyton tonsurans显示文摘We report here the first case of neonatal tinea faciei caused by Trichophyton tonsurans in China's Mainland.The mother of the infant had tinea corpris and tinea capitis while the father had tinea incongnito.The infections in the parents were mycologically confirmed to be due to Trichophyton tonsurans.Ttinea faciei in the infant was cured after two-week topical use of amorolfine cream.The mother ceased breastfeeding and took oral terbinafine for 4 weeks.No recurrence was observed in the infant during 12 months of follow-up. | Meihua Fu Yiping Ge Wei Chen Suying Feng Xiaodong She Xiaofang Li Weida Liu | 2013 | The Journal of Biomedical Research2013，27，1： | 3 |
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