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| 1 | Integration of micro-supercapacitors with triboelectric nanogenerators for a flexible self-charging power unit显示文摘便携式、便携的电子设备的快速的发展为灵活、有效的精力收获和存储单位增加了需求。通常,这些作为分离部件独立被造并且使用。此处,我们建议雕刻的简单、划算的激光为制作一个灵活自我控告的 micro-supercapacitor 力量单位(SCMPU ) 的技术,由集成摩擦电, nanogenerator (TENG ) 和 micro-supercapacitor (MSC ) 穿进一台单个设备。SCMPU 能被周围的机械运动直接控告。我们表明 SCMPU 的能力连续地驱动轻射出的二极管和商业温湿计。这调查可以支持持续自我动力的系统的开发并且为 supercapacitors 提供一个有希望的新研究应用程序。 | Jianjun Luo Feng Ru Fan Tao Jiang Zhiwei Wang Wei Tang Cuiping Zhang Mengmeng Liu Guozhong Cao Zhong Lin Wang | 2015 | Nano Research2015，8，12： | 14 |
| 2 | Construction of a host range-expanded hybrid baculovirus of BmNPV and AcNPV, and knockout of cysteinase gene for more efficient expression显示文摘AcNPV (Autographa californica nuclear polyhedrosis virus) and BmNPV(Bombyx mori nuclear polyhedrosis virus) are two principal insect-baculovirus expression systems, each having different characteristics. AcNPV has a wider host range and can infect a series of cell lines thus making it suitable for cell suspension culture expression, but the small size of the host insect, A. californica, makes AcNPV less suitable for large scale protein synthesis. In contrast, BmNPV can only infect the silkworm, Bombyx mori, which is well-known for its easy rearing and large size. These characteristics make the BmNPV system especially suitable for large-scale industrial ex-pression. To utilize the advantages of both AcNPV and BmNPV, we tried to expand their host range through homologous recombination and successfully constructed a hybrid baculovirus of AcNPV and BmNPV, designated as HyNPV. The hybrid baculovirus can infect the hosts of both AcNPV and BmNPV. Taking the human basic fibroblast growth factor (bFGF) gene as an appli-cation example, we constructed a recombinant, HyNPV-bFGF. This construct is able to express the bFGF protein both in silkworm larvae and in common-use cell lines, sf21, sf9 and High-five. Moreover, to reduce the loss of recombinant protein due to degradation by proteases that are simultaneously expressed by the baculovirus, we knocked out the cysteinase gene coding for one of the most important baculovirus proteases. This knockout mutation improves the produc-tion efficiency of the bFGF recombinant protein. | WU Xiaofeng, CAO Cuiping, XU Yaxiang & LU Xingmeng College of Animal Sciences, Zhejiang University, Huajiachi Campus, Hangzhou 310029, China | 2004 | Science China(Life Sciences)2004，47，5： | 12 |
| 3 | The effect of nitrogen annealing on lithium ion intercalation in nickel-doped lithium trivanadate显示文摘The communication reports an exploratory experimental study on the effects of nitrogen annealing on lithium ion intercalation in nickel-doped lithium trivanadate cathodic electrodes for lithium ion batteries. It shows good rate performance with discharge capacities of 348.6,252.6, 191.9 and 96.7 m Ah g^(-1)at 0.2, 0.5, 1 and 5 C,respectively. Nitrogen annealing resulted in the formation of parasitic secondary-phase Li V_2O_5 and appreciably increased tetravalent vanadium ions compensated with oxygen vacancies, which would enhance the electronic conductivity and lithium ion diffusivity and promote the interface interaction and deintercalation process, and thus lead to the enhanced lithium ion intercalation properties.The possible impacts of the parasitic secondary-phase Li V_2O_5 on the lithium ion intercalation performance have also been discussed. | Yaguang Liu Cuiping Zhang Chaofeng Liu Huanqiao Song Xihui Nan Guozhong Cao | 2016 | Science Bulletin2016，61，8： | 4 |
| 4 | Elevated CO2 differentially affects tobacco and rice defense against lepidopteran larvae via the jasmonic acid signaling pathway显示文摘Atmospheric CO_2 levels are rapidly increasing due to human activities. However, the effects of elevated CO_2(ECO_2) on plant defense against insects and the underlying mechanisms remain poorly understood. Here we show that ECO_2 increased the photosynthetic rates and the biomass of tobacco and rice plants, and the chewing lepidopteran insects Spodoptera litura and Mythimna separata gained less and more mass on tobacco and rice plants, respectively. Consistently, under ECO_2, the levels of jasmonic acid(JA), the main phytohormone controlling plant defense against these lepidopteran insects, as well as the main defense-related metabolites, were increased and decreased in insectdamaged tobacco and rice plants. Importantly, bioassaysand quantification of defense-related metabolites in tobacco and rice silenced in JA biosynthesis and perception indicate that ECO_2 changes plant resistance mainly by affecting the JA pathway. We further demonstrate that the defensive metabolites, but not total N or protein, are the main factors contributing to the altered defense levels under ECO_2. This study illustrates that ECO_2 changes the interplay between plants and insects, and we propose that crops should be studied for their resistance to the major pests under ECO_2 to predict the impact of ECO_2 on future agroecosystems. | Chengkai Lu Jinfeng qi Christian Hettenhausen Yunting Lei Jingxiong Zhang Mou Zhang Cuiping Zhang Juan Song Jing Li Guoyan Cao Saif ul Malook Jianqiang Wu | 2018 | Journal of Integrative Plant Biology2018，60，5： | 3 |
| 5 | Extrarenal Wilms’ Tumor of the Female Genital System:A Case Report and Literature Review显示文摘Extrarenal Wilms’ Tumors (ERWTs) are rare. There have been only 25 cases of ERWT arising from the female genital system reported in the literature. In this paper, we report a 60-year-old woman with a complaint of vaginal bleeding and a polypoid mass in the uterine cavity by sonography that was demonstrated as ERWT by pathology after resection. The pathological characteristics, histological origination,diagnosis, therapy and prognosis of ERWT in female reproductive system are discussed in this paper in the purpose of improving the diagnosis and therapy of this rare tumor. | Minmin Cao Cuiping Huang Yafen Wang Demei Ma | 2017 | Chinese Medical Sciences Journal2017，32，4： | 3 |
| 6 | Effect of aging treatment on microstructure and corrosion behavior of Al-Zn-Mg aluminum alloy in aqueous solutions with different aggressive ions显示文摘The microstructure and corrosion behavior of Al-Zn-Mg alloy(namely 7×××)after natural aging treatment(NAT)and artificial aging treatment(AAT)in aqueous NaCl solutions containing different aggressive ions have been investigated in current work.Results of microstructure characterization demonstrate that the aging treatment has a great influence on the grain size and precipitates.The grain size is relatively sizeable and no evident precipitates are observed in alloy after NAT comparable with that after AAT.The electrochemical corrosion behavior of alloy was studied by polarization curve and electrochemical impedance spectroscopy(EIS).The corrosion potential(E_(corr))of the aluminum alloy is more negative in 3.5 wt.%NaCl containing 0.052 wt.%NaHSO_(3)solution than that in 3.5 wt.%NaCl solutions with or without 0.907 wt.%NaHCO_(3).Charge transfer resistance(Rct)results reveal that alloy after AAT has an enhancement of corrosion resistance compare with that after NAT.With the immersion time increasing,mostly pitting spreads over the surface of the alloy only in NaCl solution,whereas exfoliation corrosion mainly occurs in NaCl solutions containing NaHSO_(3)or NaHCO_(3). | Pan Liu Lulu Hu Qinhao Zhang Cuiping Yang Zuosi Yu Jianqing Zhang Jiming Hu Fahe Cao | 2021 | Journal of Materials Science & Technology2021，，5： | 3 |
| 7 | Optimized prime editing efficiently generates glyphosate-resistant rice plants carrying homozygous TAP-IVS mutation in EPSPS显示文摘Dear Editor,Prime editing is a novel and universal CRISPR-Cas-derived precise genome-editing technology and has great potentials for applications in basic plant research and crop molecular breeding(Anzalone et al.,2019).Although low efficiency has restrained the original prime editors(PEs)from being used as a routine tool for precise genome editing in plants,an iterative update of the PEs is removing this obstacle(Lin et al.,2021;Xu et al.,2022).Recently,the Liu group reported three optimization strategies for improving prime editing efficiency(Chen et al.,2021;Nelson et al.,2022).The first strategy is based on engineered prime editing guide RNAs(epegRNAs),which were generated by incorporating structured RNA motifs to the 3′terminus of pegRNAs.This strategy enhances pegRNA stability and prevents degradation of the 3′extension(Nelson et al.,2022).The second strategy is based on the optimized PE2 protein(PEmax),which harbors a SpCas9 variant with increased nuclease activity,an additional nuclear localization signal(NLS)sequences,and a new linker between nCas9 and reverse transcriptase(Chen et al.,2021).The third strategy is based on inhibition of DNA mismatch repair(MMR)in cells(Chen et al.,2021).In this work,we tested the optimized PEs generated with these three strategies in rice,demonstrating that the optimized PEs greatly improved prime editing efficiency in rice.We named the two optimized PEs ePE3max and ePE5max:the former is comprised of the PEmax protein,an epegRNA with evopreQ1 appended to its 3′end,and a nicking sgRNA;the latter is comprised of the ePE3max system and a dominant negative OsMLH1 variant for inhibiting MMR.Using the two optimized PEs,we efficiently generated homozygous and heterozygous T173I,A174V,and P177S(TAP-IVS)mutation in EPSPS in rice,which lays a solid foundation for rice non-transgenic glyphosate-resistance breeding. | Yuanyuan Jiang Yiping Chai Dexin Qiao Junya Wang Cuiping Xin Wei Sun Zhenghong Cao Yu Zhang Yun Zhou Xue-Chen Wang Qi-Jun Chen | 2022 | Molecular Plant2022，15，11： | 3 |
| 8 | Gene analysis of an antiviral protein SP-2 from Chinese wild silkworm, Bombyx mandarina Moore and its bioactivity assay显示文摘The cDNA encoding an antiviral protein SP-2 against BmNPV was cloned from the midgut of Chinese wild silkworm, Bombyx mandarina Moore (GenBank access AY945210) based on the available informa- tion of the domesticated silkworm. Its cDNA was 855 bp encoding 284 amino acids with predicted mo- lecular weight of 29.6 kDa. Its full length in genomics was 1376 bp, including 5 exons and 4 introns. The expression analysis indicated that it was only expressed in midgut, and its expression level was higher during feeding stage of larval instars while very lower during the moltism and mature stages. The de- duced amino acid sequence of this protein showed eight-amino-acid variation compared with the counterpart of domesticated silkworm. Its antiviral activity was assayed through in vitro test. The re- sults indicated that it showed strong bioactivity against BmNPV, and its activity was 1.6 fold higher that the counterpart of domesticated silkworm. | YAO HuiPeng, HE FangQing, GUO AiQin, CAO CuiPing, LU XingMeng & WU XiaoFeng College of Animal Science, Zhejiang University, Hangzhou 310029, China | 2008 | Science China(Life Sciences)2008，51，10： | 2 |
| 9 | Phase Boundary Mapping in ZrNiSn Half-Heusler for Enhanced Thermoelectric Performance显示文摘The solubility range of interstitial Ni in the ZrNi1+xSn half-Heusler phase is a controversial issue,but it has an impact on the thermoelectric properties.In this study,two isothermal section phase diagrams of the Zr-Ni-Sn ternary system at 973K and 1173 K were experimentally constructed based on the binary phase diagrams of Zr-Ni,Zr-Sn,and Ni-Sn.The thermodynamic equilibrium phases were obtained after a long time of heating treatment on the raw alloys prepared by levitation melting.Solubilities of x<0:07 at 973 K and x<0:13 at 1173 K were clearly indicated.An intermediate-Heusler phase with a partly filled Ni void was observed,which is believed to be beneficial to the lowered lattice thermal conductivity.The highest ZT value~0:71 at 973 K was obtained for ZrNi_(1.11)Sn_(1.04).The phase boundary mapping provides an important instruction for the further optimization of ZrNiSn-based materials and other systems. | Xiaofang Li Pengbo Yang Yumei Wang Zongwei Zhang Dandan Qin Wenhua Xue Chen Chen Yifang Huang Xiaodong Xie Xinyu Wang Mujin Yang Cuiping Wang Feng Cao Jiehe Sui Xingjun Liu Qian Zhang | 2020 | Research2020，，1： | 2 |
| 10 | Coherent Mn3O4-carbon nanocomposites with enhanced energy-storage capacitance显示文摘Nanostructured Mn 3 O 4 被新奇 sonochemical 反应介绍给激活的 C (交流) ,并且产生 nanocomposites 作为 supercapacitor 电极被检验。sonication 不仅催化氧化还原作用反应而且支持了先锋的散开,与 Mn 3 在 AC 的 mesopores 内成年、一致地分布式的 O 4 nanoparticles。另外,在 sonochemical 合成的极端本地条件产出二价的锰离子和氧空缺的过多的数量。这新奇微观结构赋予了样品以优异表演,包括与为以 100 mA/g 的控告 / 解除率的交流的 93 F/g 的价值相比的 150 F/g 的一个特定的电容。一个 Li 离子电容器交付了 68 Wh/kg 的精力密度,与为在 210 W/kg 的力量密度的交流电容器的 41 Wh/kg 相比。 | Chaofeng Liu Huanqiao Song Changkun Zhang Yaguang Liu Cuiping Zhang Xihui Nan Guozhong Cao | 2015 | Nano Research2015，8，10： | 2 |
| 11 | Optimized prime editing efficiently generates heritable mutations in maize显示文摘Low efficiency is the main obstacle to using prime editing in maize(Zea mays).Recently,prime-editing efficiency was greatly improved in mammalian cells and rice(Oryza sativa)plants by engineering primeediting guide RNAs(pegRNAs),optimizing the prime editor(PE)protein,and manipulating cellular determinants of prime editing.In this study,we tested PEs optimized via these three strategies in maize.We demonstrated that the ePE5max system,composed of PEmax,epegRNAs(pegRNA-evopreQ.1),nicking single guide RNAs(sgRNAs),and MLH1dn,efficiently generated heritable mutations that conferred resistance to herbicides that inhibit 5-enolpyruvylshikimate-3-phosphate synthase(EPSPS),acetolactate synthase(ALS),or acetyl CoA carboxylase(ACCase)activity.Collectively,we demonstrate that the ePE5max system has sufficient efficiency to generate heritable(homozygous or heterozygous)mutations in maize target genes and that the main obstacle to using PEs in maize has thus been removed. | Dexin Qiao Junya Wang Min‐Hui Lu Cuiping Xin Yiping Chai Yuanyuan Jiang Wei Sun Zhenghong Cao Siyi Guo Xue‐Chen Wang Qi‐Jun Chen | 2023 | Journal of Integrative Plant Biology2023，65，4： | 1 |
| 12 | Development of a rapid and efficient BmNPV Baculovirus expression system for application in mulberry silkworm, Bombyx mori显示文摘 | Cao Cuiping Lu Xingrneng Zhao Na Yao Huipeng Wu Xiaofeng and Tan Yeping | 2006 | Current Science2006，91，12： | 1 |
| 13 | Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line显示文摘 | Wei Wang Dan Zhang Hong Zhao Ying Chen Ying Liu Cuiping Cao Lingling Han Guoliang Liu | 2010 | Regulatory Peptides2010，，1： | 1 |
| 14 | Unsupervised machine learning for discovery of promising half-Heusler thermoelectric materials显示文摘hermoelectric materials can be potentially applied to waste heat recovery and solid-state cooling because they allow a direct energy conversion between heat and electricity and vice versa.The accelerated materials design based on machine learning has enabled the systematic discovery of promising materials.Herein we proposed a successful strategy to discover and design a series of promising half-Heusler thermoelectric materials through the iterative combination of unsupervised machine learning with the labeled known half-Heusler thermoelectric materials.Subsequently,optimized zT values of~0.5 at 925 K for p-type Sc_(0.7)Y_(0.3)NiSb_(0.97)Sn_(0.03)and~0.3 at 778 K for n-type Sc_(0.65)Y_(0.3)Ti_(0.05)NiSb were experimentally achieved on the same parent ScNiSb. | Xue Jia Yanshuai Deng Xin Bao Honghao Yao Shan Li Zhou Li Chen Chen Xinyu Wang Jun Mao Feng Cao Jiehe Sui Junwei Wu Cuiping Wang Qian Zhang Xingjun Liu | 2022 | npj Computational Materials2022，，1： | 1 |
| 15 | Mechanism of seeded infiltration growth process analysed by magnetic susceptibility measurements and in situ observation显示文摘 | Haitao Cao X. Chaud J.G. Noudem Cuiping Zhang Rui Hu Jinshan Li Lian Zhou | 2010 | Ceramics International2010，，4： | 1 |
| 16 | Survival Conditions of Folding in Different Depth During Orogenesis-Deformation in Texas Creek and Chester Dome, USA显示文摘A succession of 5 FIA trends(foliation intersection or inflection axes in porphyroblasts) preserved in high temperature-low pressure regime PreCambrian rocks in the Texas Creek, Arkansas River region reflected by the fold axial plane traces and schistosity data in this region. Similar fold axial plane trace data measured in Palaeozoic rocks in Chester Dome, Vermont, which is high temperature to medium pressure regime, only preserve the effects of the youngest FIAs of the all 5 FIA sets that obtained in this region. The other three FIA sets have no equivalent fold axial planes. This difference from shallow to deeper orogenic regimes reflects decreasing competency at greater pressure with collapse and unfolding of earlier formed folds. The greater overlying load of rocks has tended to flatten all but the very largest early-formed structures, preserving only those folds that were more recently developed. | CAO Hui XU Cuiping | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 1 |
| 17 | Expression of human VEGF165 in silkworm by using a recombinant baculovirus and its bioactivity assay 显示文摘 | Xiaofeng Wu Cuiping Cao Weizheng Cui | 2004 | J Biotechnol2004，111，3： | 1 |
| 18 | An innovative inoculation technique for inoculating recombinant baculovirus into silkworm, Bombyx mori, using lipofectin显示文摘 | Xiaofeng Wu Cuiping Cao Weizheng Cui | 2004 | Research in Microbiology2004，155，4： | 1 |
| 19 | A novel long-term intravenous combined with local treatment with human amnion-derived mesenchymal stem cells for a multidisciplinary rescued uremic calciphylaxis patient and the underlying mechanism显示文摘Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis,with high mortality and no proven therapy.Here,we reported a severe uremic calciphylaxis patient with progressive skin ischemia,large areas of painful malodorous ulcers,and mummified legs.Because of the worsening symptoms and signs refractory to conventional therapies,treatment with human amnion-derived mesenchymal stem cells(hAMSCs)was approved.Preclinical release inspections of hAMSCs,efficacy,and safety assessment,including cytokine secretory ability,immunocompetence,tumorigenicity,and genetics analysis in vitro,were introduced.We further performed acute and long-term hAMSC toxicity evaluations in C57BL/6 mice and rats,abnormal immune response tests in C57BL/6 mice,and tumorigenicity tests in neonatal Balbc-nu nude mice.After the preclinical research,the patient was treated with hAMSCs by intravenous and local intramuscular injection and external supernatant application to the ulcers.When followed up to 15 months,the blood-based markers of bone and mineral metabolism improved,with skin soft tissue regeneration and a more favorable profile of peripheral blood mononuclear cells.Skin biopsy after 1-month treatment showed vascular regeneration with mature noncalcified vessels within the dermis,and 20 months later,the re-epithelialization restored the integrity of the damaged site.No infusion or local treatment-related adverse events occurred.Thus,this novel long-term intravenous combined with local treatment with hAMSCs warrants further investigation as a potential regenerative treatment for uremic calciphylaxis due to effects of inhibiting vascular calcification,stimulating angiogenesis and myogenesis,anti-inflammatory and immune modulation,multidifferentiation,re-epithelialization,and restoration of integrity. | Lianju Qin Jing Zhang Yujie Xiao Kang Liu Yugui Cui Fangyan Xu Wenkai Ren Yanggang Yuan Chunyan Jiang Song Ning Xiaoxue Ye Ming Zeng Hanyang Qian Anning Bian Fan Li Guang Yang Shaowen Tang Zhihong Zhang Juncheng Dai Jing Guo Qiang Wang Bin Sun Yifei Ge Chun Ouyang Xueqiang Xu Jing Wang Yaoyu Huang Hongqing Cui Jing Zhou Meilian Wang Zhonglan Su Yan Lu Di Wu Jingping Shi Wei Liu Li Dong Yinbing Pan Baiqiao Zhao Ying Cui Xueyan Gao Zhanhui Gao Xiang Ma Aiqin Chen Jie Wang Meng Cao Qian Cui Li Chen Feng Chen Youjia Yu Qiang Ji Zhiwei Zhang Mufeng Gu Xiaojun Zhuang Xiaolin Lv Hui Wang Yanyan Pan Ling Wang Xianrong Xu Jing Zhao Xiuqin Wang Cuiping Liu Ningxia Liang Changying Xing Jiayin Liu Ningning Wang | 2022 | Journal of Molecular Cell Biology2022，14，2： | 1 |
| 20 | A Preliminary Screening of Optimum Medium and Symbiotic Fungi for Paphiopedilum dianthum显示文摘[Objectives]This study aimed to screen the suitable medium and symbiotic fungi for tissue culture of Paphiopedilum dianthum and to establish a rapid propagation system of Paphiopedilum,so as to promote the development of planting industry and commercial application of Paphiopedilum.[Methods]Using P.dianthum as an experimental materials,the optimal culture medium for P.dianthum was selected from DE medium,Harvais modified medium and(bark+DE)liquid medium.Then,six fungal species isolated from the original habitat soil of Paphiopedilum were co-cultured with P.dianthum on the selected optimal culture medium.By comparing the morphology,the growth amount and the physiological indexes,such as chlorophyll content,soluble sugar content and root vitality of tissue culture plantlets of P.dianthum co-cultured with the six fungal species,the suitable fungal strains for symbiosis with P.dianthum were screened out.[Results]In three kinds of culture media,P.dianthum grew normally.The growth rate was higher than that in the mediums containing DE,and there were no significant differences in the content of soluble sugar from the leaves of tissue culture plantlets,which were symbiotic with the six different fungi species.Among the six fungi species growing on the optimal medium,the growing rate of XH-A was the fastest,and that of YY001 was the slowest.The growth and physiological indexes of P.dianthum co-cultured with DY1 in DE medium were higher than those in the control group.[Conclusions]DE medium was the optimal tissue culture medium for P.dianthum,and the optimal symbiotic fungus was DY1. | Cuiping CAO Man SHEN Yufeng XU Ruidong JIA Hong GE | 2021 | Agricultural Biotechnology2021，10，2： | 0 |
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