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| 1 | Fecal stream diversion and mucosal cytokine levels in collagenous colitis:A case report显示文摘In this case report, we examined the levels of cytokines expressed before and during fecal stream diversion and after intestinal continuity was restored in a patient with collagenous colitis. We report the case of a46-year-old woman with chronic, active collagenous colitis who either failed to achieve clinical remission or experienced adverse effects with the following drugs:loperamide, cholestyramine, budesonide, methotrexate and adalimumab. Due to the intractable nature of the disease and because the patient was having up to 15 watery bowel movements per day, she underwent a temporary ileostomy. Colonic biopsies were analyzed for mucosal cytokine protein levels before and during fecal stream diversion and after intestinal continuity was restored. Mucosal protein levels of interleukin(IL)-1β,IL-2, IL-6, IL-12, IL-17 A, IL-23, TNF, IFN-γ, IL-4, IL-5,IL-10 and IL-13 were all higher during active disease and decreased to non-detectable or considerably lower levels during fecal stream diversion. One month after the restoration of bowel continuity, when the patient experienced a relapse of symptoms, IL-2, IL-23 and IL-21 levels were again increased. Our results indicate that fecal stream diversion in this patient suppressed the levels of all cytokines analyzed in colonic biopsies. With the recurrence of clinical symptoms and histological changes after bowel reconstruction,the levels of primarily proinflammatory cytokines increased. Our findings support the hypothesis that a luminal factor triggers the inflammation observed in collagenous colitis. | Niki Daferera Ashok Kumar Kumawat Elisabeth Hultgren-Honquist Simone Ignatova Magnus Strom Andreas Münch | 2015 | World Journal of Gastroenterology2015，21，19： | 2 |
| 2 | The effectiveness of plant essential oils on the growth of Botrytis cinerea, Fusarium sp and Clavibacter michiganensis subsp michiganensis 显示文摘 | Daferera DJ Ziogas BN Polissiou MG | 2003 | Crop Prote2003，22，1： | 1 |
| 3 | Quantitative analysis of a-pinene and fl-myrcene in mastic gum oil using FT-Raman spectroscopy显示文摘 | Daferera D Tarantilis P A Polissiou M | 2002 | Food Chemistry2002，77，： | 1 |
| 4 | The effectiveness of plant essential oils on the growth of Botrytis cinerea , Fusarium sp. and Clavibacter michiganensis subsp. michiganensis显示文摘 | Dimitra J Daferera Basil N Ziogas Moschos G Polissiou | 2002 | Crop Protection2002，，1： | 1 |
| 5 | GC-MS Analysis of essential oils from some Greek aromatic plants and their fungitoxicity on penicillium digitatum显示文摘 | Daferera D J Ziogas B N Polissiou M G | 2000 | J Agric Food Chem2000，48，： | 1 |
| 6 | Compositions and the in vitro antimicrobial activities of the essential oils of Achillea setacea and Achillea teretifolia显示文摘 | Unlu M Daferera D Donmez E | 2002 | J Ethnopharmaeo12002，83，： | 1 |
| 7 | An association study between catalase -262C>T gene polymorphism, sodium-lithium countertrasport activity, insulin resistance, blood lipid parameters and their response to atorvastatin, in Greek dyslipidaemic patients and normolipidaemic controls显示文摘 | Maria Kosmidou Apostolos I. Hatzitolios Dimitra Molyva Nikolaos Raikos Christos Savopoulos Niki Daferera Vassileios Kokkas Antonis Goulas | 2009 | Free Radical Research2009，，4： | 1 |
| 8 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (Allium sativum)显示文摘 | KIMBARIS A C SIATIS N G DAFERERA D J | 2006 | Ultrasonics Sonochemistry2006，13，1： | 1 |
| 9 | Chemical composition and antioxidant activity of the essential oil of Clinopodium vulgare L 显示文摘 | Bektas Tepe a Arzuhan Sihoglu - Tepe Di mitra Daferera | 2007 | Food Chemistry2007，103，： | 1 |
| 10 | GC-MS Analysis of essen-tial oils from some Greek aromatic plants and their fungitoxicity onpenicillium digitatum显示文摘 | Daferera D J Ziogas B N Polissiou M G | 2000 | Journal of Agricultural and Food Chemis-try2000，48，： | 1 |
| 11 | GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum显示文摘 | DAFERERA D J ZIOGAS B N POLISSIOU M G | 2000 | J Agric Food Chem2000，48，6： | 1 |
| 12 | Ultrasound-assisted extraction of volatile compounds from citrus flowers and citrus honey显示文摘 | ALISSANDRAKIS DAFERERA TARANTILIS | 2003 | Food Chemistry2003，82，4： | 1 |
| 13 | GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxieity on Penicillium digitatum显示文摘 | Daferera DJ Ziogas BN Polissiou MG | 2000 | J Agric Food Chem2000，48，6： | 1 |
| 14 | Quantitative Analysis of α-pinene and β-myrcene in Mastic Gum Oil Using FT-Raman Spectroscopy显示文摘 | DAFERERA C P TARANTILIS P A | 2002 | Food Chemistry2002，77，： | 1 |
| 15 | Comparison of distillation and ultrasound - assisted extraction methods for the isolation of sensitive aroma compounds fromgarlie (Alliumsativum) 显示文摘 | Athanasios C Kimbaris Nikolaos G Siatis Dimitra J Daferera | 2006 | Ultrasonics Sonochemistry2006，13，1： | 1 |
| 16 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (Allium sativum)显示文摘 | KIMBARIS A C SIATIS N G DAFERERA D J et 81 | 2006 | Ultrasonics Sonochemistty2006，13，1： | 1 |
| 17 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic ( Mlium sativum) 显示文摘 | KIMBARIS A SIATIS N DAFERERA D | 2006 | Ultrasonics Sonochemistry2006，13，1： | 1 |
| 18 | Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic ( Allium sativum )显示文摘 | Athanasios C. Kimbaris Nikolaos G. Siatis Dimitra J. Daferera Petros A. Tarantilis Christos S. Pappas Moschos G. Polissiou | 2005 | Ultrasonics - Sonochemistry2005，，1： | 1 |
| 19 | Chemical composition and antioxidant activity of the essential oil of Clinopodium vulgare L 显示文摘 | Bektas Tepe a Arzuhan Sihoglu- Tepe Dimitra Daferera | 2007 | Food Chemistry2007，103，： | 1 |
| 20 | Antimicrobial and antioxidant activities of the essential oils and various extracts of Salvia tomentosa Miller (Lamiaceae)显示文摘 | TEPE B DAFERERA D SOKMEN A | 2005 | Food Chemistry2005，，9： | 1 |
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