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| 1 | Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients显示文摘AIM To evaluate the reversibility of minimal hepatic encephalopathy(MHE) following liver transplantation(LT) in Egyptian cirrhotic patients. METHODS This prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty ageand sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A(TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score(PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group. RESULTS Before LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls(P < 0.001). There was a statistically significant improvement in test values in the patient group after LT; however, their values were still significantly worse than those of the controls(P < 0.001). The PHES detected MHE in 16 patients(80%) before LT with a median value of -7 ± 3.5. The median PHES value was significantly improved following LT, reaching-4.5 ± 5(P < 0.001), and the number of patients with MHE decreased to 11(55%). The pre-transplant model for end-stage liver disease(MELD) score ≥ 15 was significantly related to the presence of post-transplant MHE(P = 0.005). More patients in whom reversal of MHE was observed had a pre-transplant MELD score < 15.CONCLUSION Reversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15. | Mahmoud A Osman Moataz M Sayed Khaled A Mansour Shereen A Saleh Wesam A Ibrahim Sara M Abdelhakam Mohamed Bahaa Wael A Yousry Hosam S Elbaz Reginia N Mikhail Azza M Hassan Ehab H Elsayed Dalia A Mahmoud | 2016 | World Journal of Hepatology2016,8,30: | 11 |
| 2 | Circulating tumor and cancer stem cells in hepatitis C virusassociated liver disease显示文摘AIM:To assess the role of circulating tumor cells(CTCs)and cancer stem cells(CSCs)in hepatitis C virus(HCV)-associated liver disease.METHODS:Blood and/or tissue samples were obtained from HCV(genotype 4)-associated hepatocellularcarcinoma patients(HCC;n=120),chronic hepatitis C patients(CH;n=30)and 33 normal control subjects(n=33).Serum levels of alpha-fetoprotein(AFP),alkaline phosphatase,and alanine and aspartate aminotransferases were measured.Cytokeratin 19(CK19)monoclonal antibody was used to enumerate CTCs,and CD133 and CD90 were used to enumerate CSCs by flow cytometry.The expression levels of the CSCs markers(CD133 and CD90)as well as telomerase,melanoma antigen encoding gene 1(MAGE1)and MAGE3 were assessed by RTPCR and quantitative real-time polymerase chain reactions.The number of CTCs and/or the expression levels of CK19,CD133,telomerase,MAGE1 and MAGE3 were correlated to the standard clinicopathologic prognostic factors and disease progression.RESULTS:Levels of AFP,alkaline phosphatase and aspartate aminotransferase were significantly different among the HCC,CH and control groups(P<0.001),whereas alanine aminotransferase differed significantly between patient(HCC and CH)and control groups(P<0.001).At the specified cutoff values determine by flow cytometry,CK19(49.8),CD90(400)and CD133(73)were significantly higher in the blood of HCC patients compared to those in the CH and control groups(P<0.001).On the other hand,CD133 at a 69.5 cutoff was significantly higher in the CH compared to the control group(P≤0.001).Telomerase,MAGE1 and MAGE3RNA were expressed in 55.71%,60.00%and 62.86%of the HCC patients,respectively,but were not detected in patients in the CH or control groups,which were statistically significant(Ps<0.001).The expression levels of telomerase,CD90,MAGE3,CD133 and CK19 were all significantly associated with high tumor grade and advanced stage in HCC patients(all P s<0.05).CONCLUSION:CTC counts and AFP,CK19,telomerase,and MAGE1/MAGE3 expression predict disease progression in patients with HCV,whereas telomerase,MAGE3,CD90,CD133 and CK19 are prognostic mark- | Abeer A Bahnassy Abdel-Rahman N Zekri Ahmed El-Bastawisy Amal Fawzy Marwa Shetta Nehal Hussein Dalia Omran Abdallah A S Ahmed Samir S El-Labbody | 2014 | World Journal of Gastroenterology2014,20,48: | 9 |
| 3 | Review of radiographic findings in COVID-19显示文摘The purpose of this study is to review the published literature for the range ofradiographic findings present in patients suffering from coronavirus disease 2019infection. This novel corona virus is currently the cause of a worldwide pandemic.Pulmonary symptoms and signs dominate the clinical picture and radiologists arecalled upon to evaluate chest radiographs (CXR) and computed tomography (CT)images to assess for infiltrates and to define their extent, distribution andprogression. Multiple studies attempt to characterize the disease course bylooking at the timing of imaging relative to the onset of symptoms. In general,plain CXR show bilateral disease with a tendency toward the lung periphery andhave an appearance most consistent with viral pneumonia. Chest CT images aremost notable for showing bilateral and peripheral ground glass and consolidatedopacities and are marked by an absence of concomitant pulmonary nodules,cavitation, adenopathy and pleural effusions. Published literature mentioningorgan systems aside from pulmonary manifestations are relatively less common,yet present and are addressed in this review. Similarly, publications focusing onimaging modalities aside from CXR and chest CT are sparse in this evolving crisisand are likewise addressed in this review. The role of imaging is examined as it iscurrently being debated in the medical community, which is not at all surprisingconsidering the highly infectious nature of Severe Acute Respiratory Syndromecoronavirus 2. | Audrey E Kaufman Sonum Naidu Sarayu Ramachandran Dalia S Kaufman Zahi A Fayad Venkatesh Mani | 2020 | World Journal of Radiology2020,12,8: | 2 |
| 4 | Effects of the spin trap agent disodium benzene-1,3-disulfonate N-oxide on intracerebtal hemorrhage in a rabbit Large clot embolic stroke model:combination studies with tissue plasminogen activator显示文摘 | Paul A Dalia M Donghuan S | 2002 | Stroke2002,33,: | 1 |
| 5 | Comprehensive risk assessment of heavy metals in surface sediments along the Egyp- tian Red Sea coast显示文摘 | Dalia M S A S Azza K Ahmed E N | 2014 | The Egyptian Journal of Aquatic Research2014,40,4: | 1 |
| 6 | Mechanical behaviour of nanocrystalline electrodeposited Ni above room temperature显示文摘 | DALIA T F VAN S H SCHAAUBLIN R | 2005 | Scripta Materialia2005,53,1: | 1 |
| 7 | Rosai-Dorfman disease: tumor biology, clinical features, pathology, and treatment 显示文摘 | Dalia S Sagatys E Sokol L | 2014 | Cancer Control2014,21,4: | 1 |
| 8 | Hepatitis B infection increases the risk of non-Hodgkin lymphoma:A meta-analysis of observational studies显示文摘 | DALIA S CHAVEZ J CASTILLO J J | 2013 | Leuk Res2013,37,: | 1 |
| 9 | Explaining the exchange rate pass-through in different prices显示文摘 | Ehsan U Choudhri Hamid Faruqee Dalia S Hakura | 2005 | Journal of International Economics2005,65,2: | 1 |
| 10 | Rosai-Dorfman disease: tumor biology, clinical features, pathology, and treatment 显示文摘 | Dalia S Sagatys E Sokol L eta| | 2014 | Cancer Control2014,21,4: | 1 |
| 11 | Synthesis of a new ion exchanger, zirconium vanadate, and its application to the separation of barium and cesium radionuclides at tracer levels显示文摘 | Kamalika Roy D.K Pal S Basu Dalia Nayak Susanta Lahiri | 2002 | Applied Radiation and Isotopes2002,,4: | 1 |
| 12 | Hepatitis B infeclion increases the risk of non-Hodgkin lymphoma: a meta-analysis of observational studies显示文摘 | Dalia S Chavez J Castillo j J | 2013 | Leuk Res2013,37,9: | 1 |
| 13 | The Energy Intensity in Lithuania during 1995 - 2009 : A LMDI Approach显示文摘 | Alvydas B Tomas B Dalia S | 2011 | Energy Policy2011,39,11: | 1 |
| 14 | Antimicrobial activity of chitosan-based films against Salmonella typhimurium and Staphylococcus aureus 显示文摘 | Jesus R Rodriguez-Nunez Jaime E6pez-Cervantes Dalia I S 4nchez-Machado | 2012 | International Journal of Food Science &Technology2012,47,10: | 1 |
| 15 | Dendritic cell and histiocytic neoplasms biology, diagnosis, and treatment显示文摘 | Dalia S Shao H Sagatys E | 2014 | Cancer Con- tro|2014,21,4: | 1 |
| 16 | Hepatitis B infection increases the risk of non-Hodgkin lymphoma: a meta-analysis of observational studies显示文摘 | Dalia S Chavez J Castillo J J | 2013 | Leuk Res2013,37,9: | 1 |
| 17 | Microbial Hemicellulases 显示文摘 | Dalia S Yuval S | 2003 | Current Opinion in Microbiology2003,6,3: | 1 |
| 18 | Hepatitis B infection increases the risk of non-Hodgkin lymphoma:a meta-analysis of observational studies显示文摘 | Dalia S Chavez J Castillo JJ | 2013 | Leuk Res2013,37,9: | 1 |
| 19 | Metabolic markers of breast cancer:enhanced choline metabolism and reduced choline-ether-phospholipid synthesis显示文摘 | Rachel KB Dalia S Dalia RS | 2002 | Cancer Research2002,62,7: | 1 |
| 20 | PAIMS 2:Alteplase combined with hep arin versus heparin in the treatment of acute pulmonaw embolism Plas minogen activator Italian multieenter study 2显示文摘 | Dalia Volta S Palla A | 1992 | I Am Coll Cardiol1992,20,3: | 1 |