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| 1 | 雄激素性秃发的中西医治疗进展显示文摘雄激素性秃发(AGA)是临床中常见的遗传相关的脱发性疾病,其发病机制尚不完全清楚,雄激素信号传导通路可能在AGA中扮演重要角色,抗雄激素治疗效果明显,极少部分患者可能因心理作用造成性功能降低,但停药后症状基本消失。以祖国医学'辨证论治'理论为指导的中医诊疗思路对于巩固疗效、降低药物副作用具有一定优势。本文从中、西医不同角度阐述AGA的治疗进展,为临床诊治提供新思路。 | 孙文 高扬 查旭山 CHEN Yujia LIU Hongru DENG Wanying HUANG Shuhong LIU Jing | 2016 | 中国医学文摘(皮肤科学)2016,33,4: | 2 |
| 2 | PM_(2.5) exposure associated with microbiota gut-brain axis:Multi-omics mechanistic implications from the BAPE study显示文摘Recent studies have shown that PM_(2.5) may activate the hypothalamus-pituitary-adrenal(HPA)axis by inducing hormonal changes,potentially explaining the increase in neurological and cardiovascular risks.In addition,an association between PM_(2.5) and gut microbiota and metabolites was established.The above evidence represents crucial parts of the gut-brain axis(GBA).In view of this evidence. | Tiantian Li Jianlong Fang Song Tang Hang Du Liang Zhao Yanwen Wang Fuchang Deng Yuanyuan Liu Yanjun Du Liangliang Cui Wanying Shi Yan Wang Jiaonan Wang Yingjian Zhang Xiaoyan Dong Ying Gao Yu Shen Li Dong Huichan Zhou Qinghua Sun Haoran Dong Xiumiao Peng Yi Zhang Meng Cao Hong Zhi Jingyang Zhou Xiaoming Shi | 2022 | The Innovation2022,3,2: | 2 |
| 3 | Autonomous Maneuver Decisions via Transfer Learning Pigeon-Inspired Optimization for UCAVs in Dogfight Engagements显示文摘This paper proposes an autonomous maneuver decision method using transfer learning pigeon-inspired optimization(TLPIO)for unmanned combat aerial vehicles(UCAVs)in dogfight engagements.Firstly,a nonlinear F-16 aircraft model and automatic control system are constructed by a MATLAB/Simulink platform.Secondly,a 3-degrees-of-freedom(3-DOF)aircraft model is used as a maneuvering command generator,and the expanded elemental maneuver library is designed,so that the aircraft state reachable set can be obtained.Then,the game matrix is composed with the air combat situation evaluation function calculated according to the angle and range threats.Finally,a key point is that the objective function to be optimized is designed using the game mixed strategy,and the optimal mixed strategy is obtained by TLPIO.Significantly,the proposed TLPIO does not initialize the population randomly,but adopts the transfer learning method based on Kullback-Leibler(KL)divergence to initialize the population,which improves the search accuracy of the optimization algorithm.Besides,the convergence and time complexity of TLPIO are discussed.Comparison analysis with other classical optimization algorithms highlights the advantage of TLPIO.In the simulation of air combat,three initial scenarios are set,namely,opposite,offensive and defensive conditions.The effectiveness performance of the proposed autonomous maneuver decision method is verified by simulation results. | Wanying Ruan Haibin Duan Yimin Deng | 2022 | IEEE/CAA Journal of Automatica Sinica2022,9,9: | 2 |
| 4 | Regulating the nanoscale intimacy of metal and acidic sites in Ru/γ-Al_(2)O_(3)for the selective conversions of lignin-derived phenols to jet fuels显示文摘Catalytic hydrodeoxygenation(HDO)of biomass-derived oxy-compounds to advanced hydrocarbon fuels usually requires bifunctional catalysts containing metals and acidic sites.The appropriate tuning of metal and/or acidic active sites at interfaces of bifunctional catalysts can significantly improve catalyst activity and product selectivity.Here,4-trifuoromethyl salicylic acid(TFMSA),as a hydrothermal stable organic acid,was employed to tailor the bifunctional interface of Ru/γ-Al_(2)O_(3)to enhance the catalytic performance on converting lignin-derived phenols to jet fuel range cycloalkanes.More than 80%phenol was converted into cyclohexane at 230°C for 1 h over Ru/γ-Al_(2)O_(3)modified by TFMSA,which was about three times higher than that over unmodified Ru/γ-Al_(2)O_(3).X-ray diffraction(XRD),Transmission electron microscope(TEM),H2 chemisorption,and energy dispersive X-ray spectroscopy(EDS)elemental mapping results indicated that Ru nanoparticles and TFMSA were well distributed onγ-Al_(2)O_(3),and a nanoscale intimacy between Ru and TFMSA was reached.Meanwhile,Fourier transform infrared spectroscopy after pyridine adsorption(Py-FT-IR)analysis proved that Brønsted acidic sites on the catalytic interfaces of TFMSA modified Ru/γ-Al_(2)O_(3)had been improved.Moreover,the kinetic and density functional theory(DFT)results suggested that the synergistic effects of adjacent Ru nanoparticles and acidic sites were crutial for promoting the rate-limiting conversion step of phenol HDO to cyclohexane. | Shanshuai Chen Weichen Wang Xue Li Puxiang Yan Wanying Han Tian Sheng Tiansheng Deng Wanbin Zhu Hongliang Wang | 2022 | Journal of Energy Chemistry2022,31,3: | 1 |
| 5 | Revealing the role of mo doping in promoting oxygen reduction reaction performance of Pt_(3)Co nanowires显示文摘Highly active and durable electrocatalysts towards oxygen reduction reaction(ORR)are imperative for the commercialization application of proton exchange membrane fuel cells.By manipulating ligand effect,structural control,and strain effect,we report here the precise preparation of Mo-doped Pt_(3)Co alloy nanowires(Pt_(3)Co-Mo NWs)as the efficient catalyst towards ORR with high specific activity(0.596 mA cm^(−2))and mass activity(MA,0.84 A mg^(−1)_(Pt)),much higher than those of undoped counterparts.Besides activity,Pt_(3)Co-Mo NWs also demonstrate excellent structural stability and cyclic durability even after 50,000 cycles,again surpassing control samples without Mo dopants.According to the strain maps and DFT calculations,Mo dopants could modify the electronic structure of both Pt and Co to achieve not only optimized oxygen-intermediate binding energy on the interface but also increased the vacancy formation energy of Co,together leading to enhanced activity and durability.This work provides not only a facile methodology but also an in-depth investigation of the relationship between structure and properties to provide general guidance for future design and optimization. | Zhiping Deng Wanying Pang Mingxing Gong Zhehui Jin Xiaolei Wang | 2022 | Journal of Energy Chemistry2022,31,3: | 0 |