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| 1 | H_(2)S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish显示文摘Background Hydrogen sulphide(H_(2)S)is considered as the third member of the gasotransmitter family,along with nitric oxide(NO)and carbon monoxide.H_(2)S has been reported to induce angiogenesis by promoting the growth,migration and tube-like structure formation of endothelial cells.Those studies were conducted in conditions of cell culture,mouse Matrigel plug assay model,rat wound healing model or rat hindlimb ischaemia model.Recent in vivo studies showed the physiological importance of H_(2)S in muscle angiogenesis.However,the importance of endogenous H_(2)S for brain angiogenesis during development remains unknown.We therefore aimed at determining the role of H_(2)S in brain vascular development.Methods and results Both knockdown and knockout of H2S-producing enzymes,cystathionineβ-synthase(cbs)and cystathionineγ-lyase(cth),using morpholino oligonucleotides and clustered regularly interspaced short palindromic repeats/Cas9-mediated mutation,impaired brain vascular development of larval zebrafish.Incubation with the slow-releasing H_(2)S donor GYY4137 alleviated the defects of brain vascular development in cbs and cth morphants.Quantitative analysis of the midbrain vascular network showed that H_(2)S enhances angiogenesis without affecting the topological structure of the brain vasculature.Mechanically,nitric oxide synthase 2a(nos2a)expression and NO production were decreased in both cbs and cth morphants.Overexpression of nos2a by coinjection of cbs or cth MO with full-length zebrafish nos2a mRNA alleviated the brain vascular developmental defects in cbs and cth morphants.Conclusion We conclude that H_(2)S promotes brain developmental angiogenesis via the NOS/NO pathway in zebrafish. | Weiqing Jiang Chen Liu Mingzhu Deng Fei Wang Xiao Ren Yilin Fan Jiulin Du Yonggang Wang | 2021 | Stroke & Vascular Neurology2021，6，2： | 2 |
| 2 | Jeans' criterion and nonextensive velocity distribution function in kinetic theory显示文摘 | Du Jiulin | 2004 | Physics Letters A2004，320，56： | 1 |
| 3 | Jeans' criterion in nonextensive statistical mechanics显示文摘 | Du Jiulin | 2004 | Physica A2004，335，12： | 1 |
| 4 | Nonextensivity and the q-distribution of a relativistic gas under an external electromagnetic field显示文摘We investigate the nonextensivity and the q-distribution of a relativistic gas under an external electromagnetic field. We derive an expression for the nonextensive parameter q based on the relativistic generalized Boltzmann equation, the relativistic q-H theorem and the relativistic version of the q-power-law distribution function in the nonextensive q-kinetic theory. We thus provide the connection between the parameter q≠1 and the spatial-temporal derivatives of the temperature field of the gas as well as the four-potential, and thereby present a clearly physical meaning for the nonextensivity for the relativistic gas. | LIU ZhiPeng GUO LiNa DU JiuLin | 2011 | Chinese Science Bulletin2011，56，34： | 1 |
| 5 | Stability of Thermonuclear Reaction Affected by Gravitational Force显示文摘 | Du Jiulin Chen Fusheng | 1992 | Astrophys Space Sci1992，195，： | 1 |
| 6 | Stability of Stellar Structure and Nonequilibrium Dynamical Characteristics of g - T Effects in Nuclear Reactions in Stellar Cores显示文摘 | Du Jiulin Chen Fusheng | 1993 | Astrophys Space Sci1993，207，： | 1 |
| 7 | Dynamical Behavior of Nuclear Reaction System Disturbed by Fluid Motion in the Core显示文摘 | Du Jiulin | 1993 | Astrophys Space Sci1993，209，： | 1 |
| 8 | 新型可遗传编码的荧光探针实现在果蝇、斑马鱼和小鼠中快速特异地示踪多巴胺显示文摘文章简介多巴胺是神经系统中一种重要的单胺类神经递质,它介导了一系列重要的生理、病理过程。如何在自由活动的动物脑中特异、精准地示踪特定时间、区域的多巴胺释放是长期以来困扰神经科学家的技术难题。 | 孙芳妙 曾健智 井淼 Jingheng Zhou 冯杰思 Scott F.Owen 骆奕辰 Funing Li 王欢 Takashi Yamaguchi 雍自昊 Yijing Gao Wanling Peng Lizhao Wang Siyu Zhang Jiulin Du Dayu Lin Min Xu Anatol C.Kreitzer Guohong Cui 李毓龙 | 2019 | 科学新闻2019，0，2： | 1 |
| 9 | Bifurcation Behaviors of the Core 3He Nuclear Reaction Diffusion System显示文摘 | Du Jiulin | 1998 | Astrophysics and Space Science1998，，2： | 1 |
| 10 | Stability of the stellar structure and nonequilibrium dynamical characteristics of (g — T) effects in nuclear reactions in stellar cores显示文摘 | Jiulin Du Fusheng Chen | 1993 | Astrophysics and Space Science1993，，1： | 1 |
| 11 | Stability of thermonuclear reaction affected by gravitational force显示文摘 | Du Jiulin Chen Fusheng | 1992 | Astrophysics and Space Science1992，，2： | 1 |
| 12 | Density fluctuations in the nuclear reaction-diffusion system and the oscillations inside stars显示文摘 | Du Jiulin | 2003 | Physica A2003，318，34： | 1 |
| 13 | Retinal bipolar cells——A model for the study of neuronal signal integration显示文摘Being the functional basis of neural networks, neuronal signal integration has been currently becoming a hot point of neuroscience research. Active and passive membrane properties of retinal bipolar cells, temporal and spatial distribution of synaptic inputs to these cells are described, and modulation of signal integration characteristics of these cells under different reti- | Jiulin Du Xiongli Yang | 1999 | Chinese Science Bulletin1999，44，19： | 0 |
| 14 | The collision frequency of electron-neutralparticle in weakly ionized plasmas with non-Maxwellian velocity distributions显示文摘The collision frequencies of electron-neutral-particle in weakly ionized complex plasmas with the non-Maxwellian velocity distributions are studied.The average collision frequencies of electron-neutral-particle in plasmas are accurately derived.We find that these collision frequencies are significantly dependent on the power-law spectral indices of non-Maxwellian distribution functions and so they are generally different from the collision frequencies in plasmas with a Maxwellian velocity distribution,which will affect the transport properties of the charged particles in plasmas.Numerically analyses are made to show the roles of the spectral indices in the average collision frequencies respectively. | Hong Wang Jiulin Du Rui Huo | 2021 | Communications in Theoretical Physics2021，73，9： | 0 |
| 15 | Efficient replacement of long DNA fragments via non-homologous end joining at norrcoding regions显示文摘Targeted double-strand breaks(DSBs)in genomes can be introduced efficiently by endonucleases(Umov et al.,2010;Jinek et al.,2012;Joung and Sander,2013),including zinc-finger nucleases,tran scription activator-like effector nu cleases,and clustered regularly in terspaced palindromic repeats(CRISPR)/Cas9.After DSBs,DNA repair is mainly via homology-directed repair(HDR)and/or non-homologous end joining(NHEJ)(Hustedt and Durocher,2016).It was reported that genomic DNA replacement can be achieved via HDR at the site of DSBs in multiple organisms(Dickinson et al.,2013;Yang et al.,2013;Zu et al.,2013),but the efficiency is still not enough for general application,in particular for replacing long DNA fragment that is more than hundreds of base pairs(bps).As NHEJ is 10-fold more active than HDR at DSB sites(Mao et al.,2008),we speculated that NHEJ can be utilized to implement long genomic DNA replacement with high efficiency. | Shanye Gu Jia Li Siyuan Li Jianbin Cao Jiwen Bu Yonggang Ren Wenjie Du Zhecong Chen Chufan Xu Mingcang Wang Lai Jiang Cheng Huang Jiulin Du | 2021 | Journal of Molecular Cell Biology2021，13，1： | 0 |
| 16 | Roadmap for rechargeable batteries:present and beyond显示文摘Rechargeable batteries currently hold the largest share of the electrochemical energy storage market,and they play a major role in the sustainable energy transition and industrial decarbonization to respond to global climate change.Due to the increased popularity of consumer electronics and electric vehicles,lithium-ion batteries have quickly become the most successful rechargeable batteries in the past three decades,yet growing demands in diversified application scenarios call for new types of rechargeable batteries.Tremendous efforts are made to developing the next-generation post-Li-ion rechargeable batteries,which include,but are not limited to solid-state batteries,lithium–sulfur batteries,sodium-/potassium-ion batteries,organic batteries,magnesium-/zinc-ion batteries,aqueous batteries and flow batteries.Despite the great achievements,challenges persist in precise understandings about the electrochemical reaction and charge transfer process,and optimal design of key materials and interfaces in a battery.This roadmap tends to provide an overview about the current research progress,key challenges and future prospects of various types of rechargeable batteries.New computational methods for materials development,and characterization techniques will also be discussed as they play an important role in battery research. | Sen Xin Xu Zhang Lin Wang Haijun Yu Xin Chang Yu-Ming Zhao Qinghai Meng Pan Xu Chen-Zi Zhao Jiahang Chen Huichao Lu Xirui Kong Jiulin Wang Kai Chen Gang Huang Xinbo Zhang Yu Su Yao Xiao Shu-Lei Chou Shilin Zhang Zaiping Guo Aobing Du Guanglei Cui Gaojing Yang Qing Zhao Liubing Dong Dong Zhou Feiyu Kang Hu Hong Chunyi Zhi Zhizhang Yuan Xianfeng Li Yifei Mo Yizhou Zhu Dongfang Yu Xincheng Lei Jianxiong Zhao Jiayi Wang Dong Su Yu-Guo Guo Qiang Zhang Jun Chen Li-Jun Wan | 2024 | Science China Chemistry2024，67，1： | 0 |
| 17 | 可遗传编码的荧光探针用于在体快速特异地检测去甲肾上腺素显示文摘文章简介在人的神经系统中有数十亿个神经元,这些细胞主要通过神经递质的释放和感知完成相互之间的通讯。去甲肾上腺素(Norepinephrine,NE)是一种单胺类的神经递质,它作用于多种肾上腺素受体。在中枢神经系统和交感神经系统中都参与诸多必要的生理过程,如感觉信号的调节、注意力的调控、清醒与睡眠、学习与记忆等。 | 冯杰思 Changmei Zhang Julieta E.Lischinsky Miao Jing Jingheng Zhou Huan Wang Yajun Zhang Ao Dong Zhaofa Wu Hao Wu Weiyu Chen Peng Zhang Jing Zou S.Andrew Hires J.Julius Zhu Guohong Cui Dayu Lin Jiulin Du 李毓龙 | 2020 | 科学新闻2020，，2： | 0 |
| 18 | Theoretical self-consistency in nonextensive statistical mechanics with parameter transformation显示文摘Self-consistency in nonextensive statistical mechanics is studied as a recourse to parameter transformation,where different nonextensive parameters are presented for various theoretical branches.The unification between the first and third choices of the average definition and that between the normal and escort distributions are both examined.The problem of parameter inversion in the generalized H theorem is also investigated.The inconsistency between the statistical ensemble pressure and molecular dynamics pressure can be eliminated.This work also verifies the equivalence of physical temperature and gravitational temperature in nonextensive statistical mechanics.In these parameter transformations,the Tsallis entropy form is observed to remain invariant. | Yahui Zheng Jiulin Du | 2021 | Communications in Theoretical Physics2021，73，12： | 0 |
| 19 | Optic tecta I superficial inter neurons detect motion in larval zebrafish显示文摘Detection of moving objects is an essential skill for animals to hunt prey,recognize conspecifics and avoid predators.The zebrafish,as a vertebrate model,primarily uses its elaborate visual system to distinguish moving objects against background scenes.The optic tectum(OT)receives and integrates inputs from various types of retinal ganglion cells(RGCs),including direction-selective(DS)RGCs and size-selective RGCs,and is required for both prey capture and predator avoidance.However,it remains largely unknown how motion information is processed within the OT.Here we performed in vivo whole-cell recording and calcium imaging to investigate the role of superficial interneurons(SINs),a specific type of optic tecta I neurons,in motion detection of larval zebrafish.SINs mainly receive excitatory synaptic inputs,exhibit transient ON-or OFF-type of responses evoked by light flashes,and possess a large receptive field(RF).One fifth of SINs are DS and classified into two subsets with separate preferred directions.Furthermore,SINs show size-dependent responses to moving dots.They are efficiently activated by moving objects but not static ones,capable of showing sustained responses to moving objects and having less visual adaptation than periventricular neurons(PVNs),the principal tecta I cells.Behaviorally,ablation of SINs impairs prey capture,which requires local motion detection,but not global looming-evoked escape.Finally,starvation enhances the gain of SINs'motion responses while maintaining their size tuning and DS.These results indicate that SINs serve as a motion detector for sensing and localizing sized moving objects in the visual field. | Chen Yin Xiaoquan Li Jiulin Du | 2019 | Protein & Cell2019，10，4： | 0 |
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