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| 1 | A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value显示文摘 | Changsong Zou Aojun Chen Lihong Xiao Heike M Muller Peter Ache Georg Haberer Meiling Zhang Wei Jia Ping Deng Ru Huang Daniel Lang Feng Li Dongliang Zhan Xiangyun Wu Hui Zhang Jennifer Bohm Renyi Liu Sergey Shabala Rainer Hedrich Jian-Kang Zhu Heng Zhang | 2017 | Cell Research2017，27，11： | 22 |
| 2 | Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis显示文摘BACKGROUND Non-alcoholic steatohepatitis(NASH) has become one of the leading causes of liver disease in the western world. In obese patients weight reduction is recommended. Up to now there are no specific guidelines for weight loss in order to reduce hepatic fat content.AIM To investigate the effects of a 24-wk guided lifestyle intervention program compared to a meal replacement regimen based on soy protein.METHODS Twenty-six subjects with NASH participated in a randomized single-center study. They were randomly assigned to either meal replacement group(MR-G)with soy-yogurt-honey preparation or to guided lifestyle change group(LC-G)with endurance activity and nutrition counselling. Serum alanine transaminase(ALT), aspartate transaminase(AST), lipid parameters, and adipokines were measured. Liver fat content and lipid composition were determined by magnetic resonance imaging and magnetic resonance spectroscopy. Body fat mass and lean body mass were assessed using Bod Pod? device. Pre-and post-intervention monitoring of parameters was performed. Statistical analyses were conducted with SPSS software, results were expressed as median(interquartile range).RESULTS Twenty-two subjects(MR-G, n = 11 and LC-G, n = 11) completed the study(9 women, 13 men; age 52.1(15.0) years, body mass index(BMI) 32.3(3.3) kg/m^2).In both groups a significant weight loss was achieved(MR-G:-6.4(3.6) kg, P <0.01; LC-G:-9.1(10.4) kg, P < 0.01). BMI dropped in both groups(MR-G:-2.3(1.5)kg/m^2, P = 0.003; LC-G:-3.0(3.4) kg/m^2, P = 0.006). Internal fat and hepatic lipid content were markedly reduced in both groups in comparable amount. There was a strong correlation between reduction in liver fat and decrease in ALT.Likewise, both groups showed an improvement in glycemic control and lipid profile. Changes in adipokines, particularly in adiponectin and leptin were closely related to intrahepatic lipid changes.CONCLUSION Comprehensive lifestyle intervention and meal replacement regimen have comparable effects on body and liver fat, as well as decrease in markers of hepatic inflammation among NASH patients. | Peter Deibert Adhara Lazaro Denise Schaffner Aloys Berg Daniel Koenig Wolfgang Kreisel Manfred W Baumstark Daniel Steinmann Martin Buechert Thomas Lange | 2019 | World Journal of Gastroenterology2019，25，9： | 3 |
| 3 | Early Mucosal Healing With Infliximab Is Associated With Improved Long-term Clinical Outcomes in Ulcerative Colitis显示文摘 | Jean Frédéric Colombel Paul Rutgeerts Walter Reinisch Dirk Esser Yanxin Wang Yinghua Lang Colleen W. Marano Richard Strauss Bj?rn J. Oddens Brian G. Feagan Stephen B. Hanauer Gary R. Lichtenstein Daniel Present Bruce E. Sands William J. Sandborn | 2011 | Gastroenterology2011，，4： | 3 |
| 4 | Ridge preservation at implants installed immediately after molar extraction. An experimental study in the dog显示文摘 | Giacomo Favero Niklaus P. Lang Enzo Santis Brismayda Garcia Gonzalez Michael T. Schweikert Daniele Botticelli | 2012 | Clin Oral Implants Res2012，，3： | 1 |
| 5 | Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis显示文摘 | Michael V. Holmes Leslie A. Lange Tom Palmer Matthew B. Lanktree Kari E. North Berta Almoguera Sarah Buxbaum Hareesh R. Chandrupatla Clara C. Elbers Yiran Guo Ron C. Hoogeveen Jin Li Yun R. Li Daniel I. Swerdlow Mary Cushman Tom S. Price Sean P. Curtis My | 2014 | The American Journal of Human Genetics2014，，2： | 1 |
| 6 | Progesterone receptor action:defining a role in breast cancer显示文摘 | Daniel AR Hagan CR Lange CA | | 0，，03： | 1 |
| 7 | Progesterone receptor action: defining a role in breast cancer显示文摘 | Daniel AR Hagan CR Lange CA | 2011 | Expert Rev Endocrinol Metab2011，6，11： | 1 |
| 8 | Early Mucosal Healing With Infliximab Is Associated With Improved Long-term Clinical Outcomes in Ulcerative Colitis显示文摘 | Jean Frédéric Colombel Paul Rutgeerts Walter Reinisch Dirk Esser Yanxin Wang Yinghua Lang Colleen W. Marano Richard Strauss Bj?rn J. Oddens Brian G. Feagan Stephen B. Hanauer Gary R. Lichtenstein Daniel Present Bruce E. Sands William J. Sandborn | 2011 | Gastroenterology2011，，4： | 1 |
| 9 | Kπ scattering for isospin 1/2 and 3/2 in lattice QCD显示文摘 | Lang C B Luka L Daniel M | 2012 | Physical Review D2012，86，05： | 1 |
| 10 | Immunode sign of experimental sepsis by cecal ligation and puneture显示文摘 | Daniel Rittirseh Markus S Huber -Lang Michael A Flied | 2009 | Nature Protocols2009，4，： | 1 |
| 11 | Downregulation of organic cation transporter 1 (SLC22A1) is associatedwith tumor progression and reduced patient survival in human cholangiocellularcarcinoma显示文摘 | Anja Lautem Michael Heise Andreas Gr?sel Maria Hoppe?Lotichius Nina Weiler Daniel Foltys Johanna Knapstein J?rn Schattenberg Arno Schad Anca Zimmermann Gerd Otto Hauke Lang Peter Galle Marcus Schuchmann Tim Zimmermann | 2013 | International Journal of Oncology2013，，4： | 1 |
| 12 | Administration of poly(ADP-ribose) polymerase inhibitor into bronchial artery attenuates pulmonary pathophysiology after smoke inhalation and burn in an ovine model显示文摘 | Atsumori Hamahata Perenlei Enkhbaatar Matthias Lange Takashi Yamaki Hiroyuki Sakurai Katsumi Shimoda Hiroaki Nakazawa Lillian D. Traber Daniel L. Traber | 2012 | Burns2012，，8： | 1 |
| 13 | Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells显示文摘 | Daniel AR Lange CA | 2009 | Proc Natl Acad Sci USA2009，106，14： | 1 |
| 14 | Administration of a Peroxynitrite Decomposition Catalyst Into the Bronchial Artery Attenuates Pulmonary Dysfunction After Smoke Inhalation and Burn Injury in Sheep显示文摘 | Atsumori Hamahata Perenlei Enkhbaatar Matthias Lange Takashi Yamaki Hiroaki Nakazawa Motohiro Nozaki Hiroyuki Sakurai Lillian D. Traber Daniel L. Traber | 2012 | Shock2012，，5： | 1 |
| 15 | Progesterone receptor action: de- fining a role in breast cancer显示文摘 | Daniel AR Hagan CR Lange CA | 2011 | Expert Rev Endocrinol Metab2011，6，3： | 1 |
| 16 | Time Profile of Oxidative Stress and Neutrophil Activation in Ovine Acute Lung Injury and Sepsis显示文摘 | Matthias Lange Csaba Szabo Daniel L. Traber Eszter Horvath Atsumori Hamahata Yoshimitsu Nakano Lillian D. Traber Robert A. Cox Frank C. Schmalstieg David N. Herndon Perenlei Enkhbaatar | 2012 | Shock2012，，5： | 1 |
| 17 | Direct Delivery of Low-Dose 7-Nitroindazole Into the Bronchial Artery Attenuates Pulmonary Pathophysiology After Smoke Inhalation and Burn Injury in an Ovine Model显示文摘 | Atsumori Hamahata Perenlei Enkhbaatar Matthias Lange Robert A. Cox Hal K. Hawkins Hiroyuki Sakurai Lillian D. Traber Daniel L. Traber | 2011 | Shock2011，，6： | 1 |
| 18 | Mechanistic aspects of inducible nitric oxide synthase-induced lung injury in burn trauma显示文摘 | Perenlei Enkhbaatar Jianpu Wang Fiona Saunders Matthias Lange Atsumori Hamahata Sebastian Rehberg John F. Parkinson Lillian D. Traber David N. Herndon Daniel L. Traber | 2011 | Burns2011，，4： | 1 |
| 19 | Early Mucosal Healing With Infliximab Is Associated With Improved Long-term Clinical Outcomes in Ulcerative Colitis显示文摘 | Jean Frédéric Colombel Paul Rutgeerts Walter Reinisch Dirk Esser Yanxin Wang Yinghua Lang Colleen W. Marano Richard Strauss Bj?rn J. Oddens Brian G. Feagan Stephen B. Hanauer Gary R. Lichtenstein Daniel Present Bruce E. Sands William J. Sandborn | 2011 | Gastroenterology2011，，4： | 1 |
| 20 | Progesterone receptor action:defining a role in breast cancer显示文摘 | Daniel AR Hagan CR Lange CA | 2011 | Expert Rev Endocrinol Metab2011，6，3： | 1 |
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