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| 1 | Combined Experimental and Numerical Investigations on the Roughness Effects on the Aerodynamic Performances of LPT Blades显示文摘The aerodynamic performance of a high-load low-pressure turbine blade cascade has been analyzed for three different distributed surface roughness levels(Ra) for steady and unsteady inflows. Results from CFD simulations and experiments are presented for two different Reynolds numbers(300000 and 70000 representative of take-off and cruise conditions, respectively) in order to evaluate the roughness effects for two typical operating conditions. Computational fluid dynamics has been used to support and interpret experimental results, analyzing in detail the flow field on the blade surface and evaluating the non-dimensional local roughness parameters, further contributing to understand how and where roughness have some influence on the aerodynamic performance of the blade. The total pressure distributions in the wake region have been measured by means of a five-hole miniaturized pressure probe for the different flow conditions, allowing the evaluation of profile losses and of their dependence on the surface finish, as well as a direct comparison with the simulations. Results reported in the paper clearly highlight that only at the highest Reynolds number tested(Re=300000) surface roughness have some influence on the blade performance, both for steady and unsteady incoming flows. In this flow condition profile losses grow as the surface roughness increases, while no appreciable variations have been found at the lowest Reynolds number. The boundary layer evolution and the wake structure have shown that this trend is due to a thickening of the suction side boundary layer associated to an anticipation of transition process. On the other side, no effects have been observed on the pressure side boundary layer. | Marco Berrino Fabio Bigoni Daniele Simoni Matteo Giovannini Michele Marconcini Roberto Pacciani Francesco Bertini | 2016 | Journal of Thermal Science2016，25，1： | 3 |
| 2 | Anti tumor effects of curcumin and structurally p-diketonemodified analogs on multidrug resistant cancer cells显示文摘 | Daniele Simoni Michele Rizzi Riccardo Rondanin | | Bioorgan Med Chemt200S0，18，2： | 1 |
| 3 | Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer′s disease 显示文摘 | Simoni E Daniele S Bottegoni G | 2012 | J Med Chem2012，55，22： | 1 |
| 4 | Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development显示文摘 | Massimo Rizzi Carlo Perego Marisa Aliprandi Cristina Richichi Teresa Ravizza Daniele Colella Jana Velískǒvá Solomon L. Moshé M.Grazia De Simoni Annamaria Vezzani | 2003 | Neurobiology of Disease2003，，3： | 1 |
| 5 | Antitumor effects of curcumin and structurally β- diketone modied analogs on muhidrug resistant cancer ceils 显示文摘 | Daniele Simoni Michele Rizzi Riccardo Rondanin | 2008 | Bioorganic & Medicinal Chemistry Letters2008，18，： | 1 |
| 6 | Novel eombretastatin analogues endowed with antitumor activity 显示文摘 | Simoni Daniele Romagnoli Romeo Baruchello Riccardo | 2006 | J Med Chem2006，49，11： | 1 |
| 7 | Large Eddy Simulation of the By-pass Transition Process under Different Inlet Turbulence Conditions显示文摘The transition process of the boundary layer developing over a flat plate with elevated inlet Free Stream Turbulence Intensity(FSTI)has been studied by means of Large Eddy Simulation(LES).To this purpose,four cases with different inflow disturbances have been tested varying the magnitude and the length scale of turbulence.LES has been performed by using the finite-volume ANSYS Fluent code.The computational domain,which was constituted by a rectangular domain with a zero thickness plate,was based on an ERCOFTAC test case in order to provide a validation with a well-known set of data by comparing the boundary layer integral parameters and mean and fluctuating streamwise velocity profiles.The four cases were discussed within the paper by looking at classical statistical properties as well as advanced post-processing tools.It was shown that the decrease in the free stream turbulence level postpones the transition location,whereas the variation of the integral length scale has a very low influence on the distribution of the time-mean flow properties.Proper Orthogonal Decomposition(POD)has been applied to the instantaneous LES flow fields in order to provide a statistical representation of the structures responsible for transition and their response to free-stream turbulence intensity and length scale.The presence of vortical filaments parallel to the wall,typically referred as boundary layer streaks,is clearly identified;their characteristic dimensions and how they change as a function of FSTI properties were analyzed within the paper. | BARSI Dario COSTA Carlo LENGANI Davide SIMONI Daniele UBALDI Marina | 2021 | Journal of Thermal Science2021，30，6： | 0 |
| 8 | Experimental and Numerical Analysis of Cavity/Mean-Flow Interaction in Low Pressure Axial Flow Turbines显示文摘The increasing performance of modern aeroengines led the research towards the optimization of machine components not deeply analyzed in the past.In this context,the mechanisms driving the interaction process between the secondary flows evolving at the hub of low-pressure turbines with the rotor-stator cavity systems have been poorly investigated in the literature.In this work,an experimental and numerical analysis of the interaction between the endwall near wall flow and the leakage flow of a real cavity system is presented.The experimental results were carried out in the annular low-pressure axial flow turbine of the University of Genova.Experimental blade loading and pressure distributions into the cavity,as well as the measured total pressure loss coefficient,have been used for a proper validation of CFD results.Both steady and unsteady calculations were carried out through the commercial solver Numeca.Particularly,several numerical approaches have been tested into this work:RANS,Non Linear Harmonic(NLH),and URANS.The most promising CFD techniques have been firstly identified by comparison with experimental results and then systematically employed to extend the analysis of secondary flow-cavity flow interaction to positions and quantities not available from the experiments.Losses characterizing the mean flow-cavity flow interaction process will be shown to cover a great amount of the overall stage losses and should be properly accounted for the design of future optimized cavity configurations. | BARSI Dario COSTA Carlo LENGANI Davide SIMONI Daniele VENTURINO Giulio ZUNINO Pietro | 2021 | Journal of Thermal Science2021，30，6： | 0 |
| 9 | Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures显示文摘Multifunctional scaffolds with host defense peptides designed for regenerative endodontics are desirable nanobiotechnological tools for dentistry.Here,different scaffolds were tested for use during the pulp revascularization process,including poly(vinyl alcohol)-PVA hydrogels or resins,collagen hydrogels and poly(vinyl alcohol)PVA/Chitosan(PVA/CS)nanofibers.Based on time to degradation(21 days),nanofibers were chosen to be incorporated with ciprofloxacin and IDR-1002(each at 50 mg/g).Nanofibers containing ciprofloxacin and IDR-1002 had anti-biofilm activity against Enterococcus faecalis,Staphylococcus aureus and a multispecies oral biofilm,besides anti-inflammatory activities.The in vivo subcutaneous tissue response to tooth fragments filled with nanofibers demonstrated a pulp-like tissue formation,when compared to empty teeth fragments.Thus,we designed a strong antimicrobial,immunomodulatory and regenerative candidate for pulp revascularization and regeneration procedures. | Mauricio Gonçalves da Costa Sousa Gabriela Conceiçao de Almeida Danilo Cesar Martins Mota Rosiane Andrade da Costa Simoni Campos Dias Samuel Nunes Limberger Frank Ko Li Ting Lin Evan FHaney Hashem Etayash Beverlie Baquir Michael J.Trimble Ya Shen Zheng Su Markus Haapasalo Daniel Pletzer Letícia Chaves de Souza Glaucia Schuindt Teixeira Renato M.Silva Robert E.W.Hancock Octavio Luiz Franco Taia Maria Berto Rezende | 2022 | Bioactive Materials2022，7，10： | 0 |
| 10 | An Experimental Investigation of the Dissipation Mechanisms in the Suction Side Boundary Layer of a Turbine Blade显示文摘现在的工作是作者在针对在汽轮机片调查界面层转变现象的最近的年里执行的一项广泛的试验性的活动的部分。串联的大规模和先进 LDV 乐器学和精确探查穿越机制的使用导致了空间分辨率的高度和大小的高精确性。在涡轮机械片决定侧面损失的主要驱散机制是界面层操作了由的在内的吝啬的运动的变丑的工作粘滞、狂暴砍压力。在现在的报纸,粘滞的本地人和狂暴的变丑工作直接从界面层平均数速度和雷纳兹的详细大小被评估了砍应力。结果显示出分布和相对重要性粘滞、狂暴对损失生产的贡献,在有界面层的关系,沿着汽轮机发生的状态介绍。 | Francesca Satta Daniele Simoni Marina Ubaldi Pietro Zunino | 2008 | Journal of Thermal Science2008，17，4： | 0 |
| 11 | Experimental Analysis of the Aerodynamic Performance of an Innovative Low Pressure Turbine Rotor显示文摘In the present work the aerodynamic performances of an innovative rotor blade row have been experimentally investigated. Measurements have been carried out in a large scale low speed single stage cold flow facility at a Reynolds number typical of aeroengine cruise, under nominal and off-design conditions. The time-mean blade aerodynamic loadings have been measured at three radial positions along the blade height through a pressure transducer installed inside the hollow shaft, by delivering the signal to the stationary frame with a slip ring. The time mean aerodynamic flow fields upstream and downstream of the rotor have been measured by means of a five-hole probe to investigate the losses associated with the rotor. The investigations in the single stage research turbine allow the reproduction of both wake-boundary layer interaction as well as vortex-vortex interaction. The detail of the present results clearly highlights the strong dissipative effects induced by the blade tip vortex and by the momentum defect as well as the turbulence production, which is generated during the migration of the stator wake in the rotor passage. Phase-locked hot-wire investigations have been also performed to analyze the time-varying flow during the wake passing period. In particular the interaction between stator and rotor structures has been investigated also under off-design conditions to further explain the mechanisms contributing to the loss generation for the different conditions. | Infantino Daniele Satta Francesca Simoni Daniele Ubaldi Marina Zunino Pietro Bertini Francesco | 2016 | Journal of Thermal Science2016，25，1： | 0 |
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