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| 1 | Hepatocellular carcinoma: From clinical practice to evidence-based treatment protocols显示文摘Hepatocellular carcinoma(HCC) is one of the major malignant diseases in many healthcare systems. The growing number of new cases diagnosed each year is nearly equal to the number of deaths from this cancer. Worldwide, HCC is a leading cause of cancerrelated deaths, as it is the fifth most common cancer and the third most important cause of cancer related death in men. Among various risk factors the two are prevailing: viral hepatitis, namely chronic hepatitis C virus is a well-established risk factor contributing to the rising incidence of HCC. The epidemic of obesity and the metabolic syndrome, not only in the United States but also in Asia, tend to become the leading cause of the long-term rise in the HCC incidence. Today, the diagnosis of HCC is established within the national surveillance programs in developed countries while the diagnosis of symptomatic, advanced stage disease still remains the characteristic of underdeveloped countries. Although many different staging systems have been developed and evaluated the BarcelonaClinic Liver Cancer staging system has emerged as the most useful to guide HCC treatment. Treatment allocation should be decided by a multidisciplinary board involving hepatologists, pathologists, radiologists, liver surgeons and oncologists guided by personalized-based medicine. This approach is important not only to balance between different oncologic treatments strategies but also due to the complexity of the disease(chronic liver disease and the cancer) and due to the large number of potentially efficient therapies. Careful patient selection and a tailored treatment modality for every patient, either potentially curative(surgical treatment and tumor ablation) or palliative(transarterial therapy, radioembolization and medical treatment, i.e., sorafenib) is mandatory to achieve the best treatment outcome. | Danijel Galun Dragan Basaric Marinko Zuvela Predrag Bulajic Aleksandar Bogdanovic Nemanja Bidzic Miroslav Milicevic | 2015 | World Journal of Hepatology2015，7，20： | 13 |
| 2 | Is diabetic cardiomyopathy a specific entity?显示文摘Diabetes mellitus(DM) is characterised by hyperglycemia, insulin resistance and metabolic dysregulation leading to diastolic and systolic dysfunction in diabetes. In this review, the pathogenetic and pathomorphological changes leading to diastolic and systolic dysfunction in diabetes are discussed. Changes in metabolic signalling pathways, mediators and effectors contribute to the pathogenesis of cardiac dysfunction in DM called diabetic cardiomyopathy(DC). Echocardiographic studies report on the association between DM and the presence of cardiac hypertrophy and myocardial stiffness that lead to diastolic dysfunction. More recently reported echocardiographic studies with more sensitive techniques, such as strain analysis, also observed systolic dysfunction as an early marker of DC. Depression of systolic and diastolic function is continuum and the line of separation is artificial. To conclude, according to current knowledge, DC is expected to be a common single phenotype that is caused by different pathogenetic and pathomorphological changes leading to diastolic and systolic dysfunction in diabetes. | Mitja Letonja Danijel Petrovi | 2014 | World Journal of Cardiology2014，6，1： | 7 |
| 3 | Monoclonal immunoscintigraphy for detection of metastasis and recurrence of colorectal cancer显示文摘AIM:To assess the clinical role of monoclonal immunoscintigraphy for the detection of metastasis and recurrence of colorectal cancer.METHODS:Monoclonal immunoscintigraphy was performed in patients operated on for colorectal adenocar-cinoma suspected of local recurrence and metastatic disease.The results were compared with conventional diagnostics.RESULTS:Immunoscintigraphic investigation was done in 53 patients.Tumor recurrence occurred in 38 patients,and was confirmed by other diagnostic modalities in 35.In 15 patients,immunoscintigraphic findings were negative,and confirmed in 14 with other diagnostic methods.Comparative analysis confirmed good correlation of immunoscintigraphic findings and the results of conventional diagnostics and the level of tumor marker carcinoembryonic antigen.Statistical analysis of parameters of radiopharmaceutical groups imacis,indimacis and oncoscint presented homogenous characteristics all of three radiopharmaceuticals.The analysis of immunoscintigraphic target focus was clearly improved using tomography.CONCLUSION:Immunoscintigraphy is highly specific and has a good predictive value in local recurrence of colorectal cancer. | Vera Artiko Ana Koljevic Markovi Dragana obi-aranovi Milorad Petrovi Andrija Anti Mirjana Stojkovi Marinko Zuvela Djordjije aranovi Milica Stojkovi Neboja Radovanovi Danijel Galun Aleksandar Milovanovi Jovica Milovanovi Anica Bobi-Radovanovi Zoran Krivokapic Vladimir Obradovi | 2011 | World Journal of Gastroenterology2011，17，19： | 4 |
| 4 | Analysis of recoverable and permanent components of threshold voltage shift in NBT stressed p-channel power VDMOSFET显示文摘In this study we investigate the dynamic recovery effects in IRF9520 commercial p-channel power vertical double diffused metal–oxide semiconductor field-effect transistors(VDMOSFETs) subjected to negative bias temperature(NBT)stressing under the particular pulsed bias. Particular values of the pulsed stress voltage frequency and duty cycle are chosen in order to analyze the recoverable and permanent components of stress-induced threshold voltage shift in detail. The results are discussed in terms of the mechanisms responsible for buildup of oxide charge and interface traps. The partial recovery during the low level of pulsed gate voltage is ascribed to the removal of recoverable component of degradation, i.e., to passivation/neutralization of shallow oxide traps that are not transformed into the deeper traps(permanent component).Considering the value of characteristic time constant associated with complete removal of the recoverable component of degradation, it is shown that by selecting an appropriate combination of the frequency and duty cycle, the threshold voltage shifts induced under the pulsed negative bias temperature stress conditions can be significantly reduced, which may be utilized for improving the device lifetime in real application circuits. | Danijel Dankovi Ninoslav Stojadinovi Zoran Priji Ivica Mani Vojkan Davidovi Aneta Priji Snezana Djoric-Veljkovi Snezana Golubovi | 2015 | Chinese Physics B2015，24，10： | 1 |
| 5 | A GIS based component-oriented integrated system for estimation visualization and analysis of road traffic air pollution显示文摘 | DANIJEl R PETER J S | 1999 | Environ Modelling & Software1999，14，6： | 1 |
| 6 | A GIS based component - oriented integrated system for estimation, visualization and analysis of road traffic air pollution显示文摘 | Danijel Rebolj Peter J Stunn | 1999 | Environmental Modelling & Software1999，，3： | 1 |
| 7 | A Review of Oxidative Stress Related Genes and New Antioxidant Therapy in Diabetic Nephropathy显示文摘 | Jana Makuc Danijel Petrovic | 2011 | Cardiovascular and Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular and Hematological Agents)2011，，： | 1 |
| 8 | Is There any Benefit from Expanding the Criteria for the Resection of Hepatocellular Carcinoma in Cirrhotic Liver? Experience from a Developing Country显示文摘 | Danijel Galun Predrag Bulajic Marinko Zuvela Dragan Basaric Tatjana Ille Miroslav Milicevic | 2012 | World Journal of Surgery2012，，7： | 1 |
| 9 | Integrating resource production and construc- tion using BIM 显示文摘 | Babic Nenad Cus Podbreznik Peter 1Kebolj Danijel | 2010 | Automation in Construction vl 9 n5 p539-5432010，，： | 1 |
| 10 | Survival of neurally induced mesenchymal cells may determine degree of motor recovery in injured spinal cord rats显示文摘 | Arshak R. Alexanian Wai-Meng Kwok Danijel Pravdic Dennis J. Maiman Michael G. Fehlings | 2010 | Restorative Neurology and Neuroscience2010，，6： | 1 |
| 11 | Adaptive Kalman Filter- Based Load Torque Compensator for Improved SI Engine I- dle Speed Control 显示文摘 | Danijel P Josko D Senior Ilya K | 2009 | IEEE Transactions on Control Sys- tems Technology2009，，： | 1 |
| 12 | Multi-criteria analysis as a tool for sustainability assessment of a waste management model显示文摘 | Biljana Milutinovi? Gordana Stefanovi? Michele Dassisti Danijel Markovi? Goran Vu?kovi? | 2014 | Energy2014，，： | 1 |
| 13 | Higher mean platelet volume determined shortly after the symptom onset in acute ischemic stroke patients is associated with a larger infarct volume on CT brain scans and with worse clinical outcome显示文摘 | Slaven Pikija Danijel Cvetko Martina Hajduk Vladimir Trkulja | 2009 | Clinical Neurology and Neurosurgery2009，，7： | 1 |
| 14 | Grid implementation of the weather research and forecasting model 显示文摘 | Davor Davidovi6 Karolj Skala Danijel Belu:i6 | 2010 | Earth Science Informatics2010，3，4： | 1 |
| 15 | Residual dyebath purification using a system of constructed wetland 显示文摘 | Alenka Ojstrsek Fakin Darinka Danijel Vrhovsek | 2007 | Dyes Pigments2007，74，3： | 1 |
| 16 | Adaptive control of automotive electronic throttle 显示文摘 | Danijel Pavkovic | 2006 | Control Engineering Practice2006，14，2： | 1 |
| 17 | Residual Dyebath Purification Using a System of Constructed Wetland 显示文摘 | Alenka Ojstrsek Darinka Fakin Danijel Vrhovsek | 2007 | Dyes and Pigments2007，，74： | 1 |
| 18 | Dynamic Model of a Natural Water Circulation Boiler Suitable for On-line Monitoring of Fossil/Alternative Fuel Plants 显示文摘 | Almir S Stjepko K Danijel P | 2014 | En- ergy Conversion and Management2014，87，11： | 1 |
| 19 | Nestin expression in glial and neuronal progenitors of the developing human spinal ganglia显示文摘 | Katarina Vukojevic Danijel Petrovic Mirna Saraga-Babic | 2009 | Gene Expression Patterns2009，，2： | 1 |
| 20 | A model-based traction control strategy non-reliant on wheel slip information显示文摘 | Josko Deura Danijel Pavkovic Gilberto Burgio | 2011 | Vehicle System Dynamics2011，49，8： | 1 |
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