|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of the short-term and long-term outcomes of laparoscopic hysterectomies and of abdominal hysterectomies: a case study of 4,895 patients in the Guangxi Zhuang Autonomous Region, China显示文摘Background: To evaluate the short-term and long-term outcomes after laparoscopic hysterectomy(LH) compared with abdominal hysterectomy(AH) in case of benign gynecological disease. Methods: A multi-center cohort retrospective comparative study of population among 4,895 hysterectomies(3,539 LH vs.1,356 AH) between 2007 and 2013 was involved. Operative time(OT), estimated blood loss(EBL), intra-operative and post-operative complications, passing flatus; days with indwelling catheter, questionnaires covering pelvic floor functions and sexual functions were assessed.Results: The EBL(174.1±157.4 vs. 263.1±183.2 cc, LH and AH groups, respectively), passing flatus(38.7±14.1 vs. 48.1±13.2 hours), days with indwelling catheter(1.5±0.6 vs. 2.2±0.8 days), use of analgesics(6.5% vs. 73.1%), intra-operative complication rate(2.4% vs. 4.1%), post-operative complication rate(2.3% vs. 5.7%), post-operative constipation(12.1% vs. 24.6%), mild and serious stress urinary incontinence(SUI) post-operative(P<0.001; P=0.014), and proportion of Female Sexual Functioning Index(FSFI) total score <26.55 post-operative(P<0.001) of the LH group were significantly less than those of AH group. There wereno significant differences in OT(106.5±34.5 vs. 106.2±40.3 min) between the two groups.Conclusions: LH is a safe and efficient operation for improving patients' long-term quality of life(Qo L), and LH is a cost-effectiveness procedure for treating benign gynecological disease. LH is superior to AH due to reduced EBL, reduced post-operative pain and earlier passing flatus. | Hongying He Zhijun Yang Dingyuan Zeng Jiangtao Fan Xiaoxia Hu Yuan Ye Hua Bai YanmingJiang Zhong Lin Zhiying Lei Xinlin Li Lian Li Jinghua Gan Ying Lan Xiongzhi Tang Danxia Wang Junsong Jiang Xiaoyan Wu Meiying Li Xiaoqing Ren Xiaomin Yang Mei Liu Qinmei Wang Fuyan jiang Li Li | 2016 | Chinese Journal of Cancer Research2016，28，2： | 6 |
| 2 | Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria显示文摘Infections caused by drug-resistant“superbugs”pose an urgent public health threat due to the lack of effective drugs;however, certain mammalian proteins with intrinsic antibacterial activity might be underappreciated. Here, we reveal an antibacterial property against Gram-negative bacteria for factors VII, IX and X, three proteins with well-established roles in initiation of the coagulation cascade. These factors exert antibacterial function via their light chains (LCs). Unlike many antibacterial agents that target cell metabolism or the cytoplasmic membrane, the LCs act by hydrolyzing the major components of bacterial outer membrane, lipopolysaccharides, which are crucial for the survival of Gram-negative bacteria. The LC of factor VII exhibits in vitro efficacy towards all Gram-negative bacteria tested, including extensively drug-resistant (XDR) pathogens, at nanomolar concentrations. It is also highly effective in combating XDR Pseudomonas aeruginosa and Acinetobacter baumannii infections in vivo. Through decoding a unique mechanism whereby factors VII, IX and X behave as antimicrobial proteins, this study advances our understanding of the coagulation system in host defense, and suggests that these factors may participate in the pathogenesis of coagulation disorder-related diseases such as sepsis via their dual functions in blood coagulation and resistance to infection. Furthermore, this study may offer new strategies for combating Gram-negative “superbugs”. | Jinwu Chen Xiaojie Li Ling Li Ting Zhang Qing Zhang Fangming Wu Diyue Wang Hongze Hu Changlin Tian Dongsheng Liao Liang Zhao Danxia Song Yongyun Zhao Chuanfang Wu Xu Song | 2019 | Cell Research2019，29，9： | 6 |
| 3 | The evolution of China’s regulation of agricultural biotechnology显示文摘To ensure safe use of genetically modified organisms(GMOs),since 1993,China has made great efforts to establish and improve the safety regulatory system for GMOs.Here,we summarize and analyze the regulatory framework of agricultural GMOs,and the progress in regulatory approval of GM crops in China.In general,the development of GMO safety regulations underwent four stages:exploration(1993–2000),development(2001–2010),improvement(2011–2020)and current(2021-present)stage.The first formal regulation was promulgated in 1993,which provided a basis for further development of the regulations,during the exploration stage,when insect-resistant GM cotton,expressing genes from Bacillus thuringiensis(Bt),was approved for cultivation.During the development stage,the Chinese government issued a series of administrative measures,which covered almost all the fields relative to GMO safety when the basic regulatory system was established.Along with the controversy over GMO safety,the regulations have been further,and greatly improved,during improvement stage.From 2021,a few additional revisions have been made,and meanwhile,the new regulation on gene-edited crops was introduced with the development of biotechnology,forming a relative complete regulation and law system for China.The well-developed GMO regulations establishes a firm basis for safe use of GM crops in China.Currently,GM cotton and GM papaya have been widely grown on a large scale in China that have brought great economic and ecological benefits.In addition,12 corn events,3 soybean events,and 2 rice events have also obtained biosafety certification,but presently,these lines have yet to enter commercial production.However,several GM soybean and corn events have entered pilot industrialization,and can soon be expected to be commercially grown in China.In addition to planting,six GM crops,including soybean,corn,cotton,canola,papaya and sugar beet,with a total of 64 events,have been approved for import as processing material in China. | Jingang Liang Xiaowei Yang Yue Jiao Danxia Wang Qiang Zhao Yu Sun Yunhe Li Kongming Wu | 2022 | aBIOTECH2022，3，4： | 2 |
| 4 | miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2显示文摘 | Wei Zhu DanXia Zhu Shiqiang Lu Tongshan Wang Jian Wang Binghua Jiang Yongqian Shu Ping Liu | 2012 | Medical Oncology2012，，1： | 1 |
| 5 | Studies on glass transition temperature of ehitosan with four techniques 显示文摘 | Dong Yanming Ruan Yonghong Wang Huiwu Zhao Yaging Bi Danxia | 2004 | Journal of Applied Polymer Science2004，93，15： | 1 |
| 6 | The initial-boundary value problem of a nonlinear thermoelastic beam equations显示文摘 | ZHANG Jianwen WANG Danxia | 2010 | Applied Mechanics and Materials2010，2932，： | 1 |
| 7 | Laparoscopic uterine fibroids in addition to surgery and other clinical effects of conventional open surgery 显示文摘 | Wang Danxia | 2009 | Shanxi Medical Journal2009，38，7： | 1 |
| 8 | Research on the Professional Development Mode of Primary and Secondary School English Teachers显示文摘In this paper, we conduct research on the professional development mode of primary and the secondary school English teachers. Teacher training is an effective way to promote the teachers’ professional development that is an important content of teacher education, and teachers’ pre-service training, entry education together constitute a complete content of teacher education, teacher training, of course and is also the need of teachers’ lifelong learning, for the national government attached great importance to teachers’ training work. English teaching is a kind of creative and complicated work, and whole teaching activity involves teachers, students, teaching objective and the teaching content, teaching means and teaching links such as basic elements. This paper proposes the novel perspective of the professional development mode for teachers that will be meaningful. | Lijun Wang Danxia Liu | 2016 | International Journal of Technology Management2016，，5： | 0 |
| 9 | Fast algorithm for viscous Cahn-Hilliard equation显示文摘The main purpose of this paper is to solve the viscous Cahn-Hilliard equation via a fast algorithm based on the two time-mesh(TT-M)finite element(FE)method to ease the problem caused by strong nonlinearities.The TT-M FE algorithm includes the following main computing steps.First,a nonlinear FE method is applied on a coarse time-meshτ_(c).Here,the FE method is used for spatial discretization and the implicit second-orderθscheme(containing both implicit Crank-Nicolson and second-order backward difference)is used for temporal discretization.Second,based on the chosen initial iterative value,a linearized FE system on time fine mesh is solved,where some useful coarse numerical solutions are found by Lagrange’s interpolation formula.The analysis for both stability and a priori error estimates is made in detail.Numerical examples are given to demonstrate the validity of the proposed algorithm.Our algorithm is compared with the traditional Galerkin FE method and it is evident that our fast algorithm can save computational time. | Danxia WANG Yaqian LI Xingxing WANG Hongen JIA | 2022 | Frontiers of Mathematics in China2022，17，4： | 0 |
| 10 | Plant latent defense response to microbial non-pathogenic factors antagonizes compatibility显示文摘Unlike microbe-associated molecular patterns(MAMPs)that are readily targeted by host immunity,microbial non-pathogenic factors(NPFs)appear negligible as they do not elicit defense.Little is known about whether and how NPFs may be monitored by hosts to control compatibility.Herein,a forward genetic screening isolated an Arabidopsis mutant with a loss of plant-rhizobacteria mutualism,leading to the disclosure of a plant latent defense response(LDR)to NPFs.The activation of LDR in the mutant,named rol1 for regulator of LDR 1,is triggered by several non-pathogenic volatile organic compounds and antagonizes plant compatibility with the beneficial bacterium Bacillus amyloliquefaciens GB03.The activation of LDR in rol1 is mediated through the prokaryotic pathway of chloroplastic lipid biosynthesis.The rol1 root microbiome showed a reduced proportion of the Bacillaceae family.We propose that,parallel to the forefront immunity to MAMPs,LDR to certain NPFs provides a hidden layer of defense for controlling compatibility with commensal or beneficial microbes. | Yu Yang Shenglan Chen Xiaoxuan Wu Li Peng Juan I.Vílchez Richa Kaushal Xiaomin Liu Sunil K.Singh Danxia He Fengtong Yuan Suhui Lv Rafael J.L.Morcillo Wei Wang Weichang Huang Mingguang Lei Jian-Kang Zhu Paul W.Paré Huiming Zhang | 2022 | National Science Review2022，9，8： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员