|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | FTIR spectroscopic comparison of serum from lung cancer patients and healthy persons显示文摘 | Xin Wang Xiang Shen Daping Sheng | 2014 | Spectrochimica Acta2014，122，7： | 1 |
| 2 | Decellularized Disc Hydrogels for hBMSCs tissue-specific differentiation and tissue regeneration显示文摘Tissue specificity,a key factor in the decellularized tissue matrix(DTM),has shown bioactive functionalities in tuning cell fate-e.g.,the differentiation of mesenchymal stem cells.Notably,cell fate is also determined by the living microenvironment,including material composition and spatial characteristics.Herein,two neighboring tissues within intervertebral discs,the nucleus pulposus(NP)and annulus fibrosus(AF),were carefully processed into DTM hydrogels(abbreviated DNP-G and DAF-G,respectively)to determine the tissue-specific effects on stem cell fate,such as specific components and different culturing methods,as well as in vivo regeneration.Distinct differences in their protein compositions were identified by proteomic analysis.Interestingly,the fate of human bone marrow mesenchymal stem cells(hBMSCs)also responds to both culturing methods and composition.Generally,hBMSCs cultured with DNP-G(3D)differentiated into NP-like cells,while hBMSCs cultured with DAF-G(2D)underwent AF-like differentiation,indicating a close correlation with the native microenvironments of NP and AF cells,respectively.Furthermore,we found that the integrin-mediated RhoA/LATS/YAP1 signaling pathway was activated in DAF-G(2D)-induced AF-specific differentiation.Additionally,the activation of YAP1 determined the tendency of NP-or AF-specific differentiation and played opposite regulatory effects.Finally,DNP-G and DAF-G specifically promoted tissue regeneration in NP degeneration and AF defect rat models,respectively.In conclusion,DNP-G and DAF-G can specifically determine the fate of stem cells through the integrin-mediated RhoA/LATS/YAP1 signaling pathway,and this tissue specificity is both compositional and spatial,supporting the utilization of tissue-specific DTM in advanced treatments of intervertebral disc degeneration. | Yizhong Peng Xiangcheng Qing Hui Lin Donghua Huang Jinye Li Shuo Tian Sheng Liu Xiao Lv Kaige Ma Rui Li Zilong Rao Ying Bai Songfeng Chen Ming Lei Daping Quan Zengwu Shao | 2021 | Bioactive Materials2021，6，10： | 1 |
| 3 | Suspected Yellow Fever Case Determined to be Adverse Vaccine Reaction显示文摘Jiangxi Provincial Center for Disease Control and Prevention(Jiangxi CDC)received an alert at 23:45 on November 7,2019 from Nanchang Customs that yellow fever virus was detected in a foreign national.On November 8,county,municipal,and provincial CDCs of Jiangxi Province carried out epidemiological investigations to show that the suspected case was found in a 35-year-old male patient from Addis Ababa,Ethiopia.On November 5,this patient began to have yellow-fever-like symptoms such as onset of fever,chills,and headache. | Sheng Ding Ying Xiong Huanhong Pan Zhongjian Li Song Tang Xingkui Huang Jianxiong Li Yong Shi Weijie Fu Huijian Cheng Daping Che Xiaoqing Liu Wentao Song Jingwen Wu Yisheng zhou Jian Zhang Chao Li Jiandong Li | 2019 | China CDC weekly2019，1，4： | 0 |
| 4 | An Outbreak of Dengue Virus Type 1--Jiangxi Province,China,2019显示文摘What is known about this topic?Dengue fever is an acute febrile illness caused by four types of dengue virus(DENV 1–4),and is a mosquitoborne infectious disease.The incidence of dengue has increased dramatically around the world in recent decades.An estimated of 3.9 billion people in 128 countries are at risk of infection with dengue viruses,70%of whom are in Asia.In 2017,the first local infections of dengue virus(DENV-2)in Jiangxi Province was reported in Zhanggong District,Ganzhou City.What is added by this report?From August to September 2019,the first dengue outbreak happened in Xin’gan County,where 81 local dengue fever cases were reported,35 were laboratoryconfirmed cases,and 46 were clinically-diagnosed cases;all cases were dengue virus type 1.The DENV-virus strains isolated from the cases of Xin’gan County were close to the strains isolated in Singapore(MF033254|25657|Singapore|2016)and Henan(MK905537|He nan201903|China:Henan Province|2019).What are the implications for public health practice?The outbreak might have been caused by imported cases or covert infections.The outbreak in Xin’gan County indicated that more proactive countermeasures should be taken during the dengue epidemic period such as intensifying surveillance for dengue cases,virus serotype,and Aedes vector density and strengthening cooperation with customs and tourism departments.Moreover,the outbreak should prompt training in medical institutions and improved ability for doctor’s to diagnose dengue fever,which is very important for early detection of dengue cases and taking preventive measures. | Fuqiang Yang Guanghui Xia Zhili Zeng Zhongjian Li Huijian Cheng Daping Che Jun Zong Jianxiong Li Tian Gong Guihua Liu Weidong Zhou Bihai Wei Xiaobo Liu Jiandong Li Sheng Ding | 2020 | China CDC weekly2020，2，35： | 0 |
| 5 | Corrigendum to‘Decellularized disc hydrogels for hBMSC tissue-specific differentiation and tissue regeneration’[Bioactive Materials 6(2021)3541-3556]显示文摘The authors regret missing out the below change in the acknowledgment section of the article.The original sentence reads as'This work was supported by the Major Research Plan of National Natural Science Foundation of China[No.91649204],the National Key Research and Development Program of China[2016YFC1100100],…'and the same has been corrected to'This work was supported by the National Key Research and Development Program of China[2016YFC1100100],the Major Research Plan of National Natural Science Foundation of China[No.91649204],…'and the same has been corrected to'This work was supported by the National Key Research and Development Program of China[2016YFC1100100],the Major Research Plan of National Natural Science Foundation of China[No.91649204],…'. | Yizhong Peng Xiangcheng Qing Hui Lin Donghua Huang Jinye Li Shuo Tian Sheng Liu Xiao Lv Kaige Ma Rui Li Zilong Rao Ying Bai Songfeng Chen Ming Lei Daping Quan Zengwu Shao | 2022 | Bioactive Materials2022，7，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员