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| 1 | The effect of applied voltages on the structure,apatite-inducing ability and antibacterial ability of micro arc oxidation coating formed on titanium surface显示文摘The micro arc oxidation(MAO)coatings with different concentrations of Ca,P and Zn elements are successfully formed on the titanium substrate at the different applied voltages.After MAO treatment,the MAO coating exhibits the porous surface structure and composed of anatase and rutile TiO2 phases.Meanwhile,the average size and density of micro-pores on the MAO coatings have been modified via the adjusting the applied voltages.In addition,the contents of the incorporated elements such as Zn,Ca and P elements in the MAO coatings have been optimized.The bonding strength test results reveal that the MAO coating shows higher bonding strength,which is up to 45±5 MPa.Compared to the pure Ti plate,the MAO coating formed at 350 and 400 V show good apatite-inducing ability.Meanwhile,the MAO coating containing Zn,Ca and P elements have better antibacterial ability for E.coli and S.aureus.Thus,the incorporation of Zn,Ca and P elements was an effective method to improve the antibacterial ability.Moreover,the concentrations of Zn,Ca and P elements could be adjusted with the changing of the applied voltages.As a result,the enhancement of the antibacterial ability on the MAO coating surfaces was depended on the comprehensive effect of the incorporated elements and the surface property of MAO coatings. | Qing Du Daqing Wei Yaming Wang Su Cheng Shang Liu Yu Zhou Dechang Jia | 2018 | Bioactive Materials2018，3，4： | 6 |
| 2 | Activation of mitogen-activated protein kinases in satellite glial cells of the trigeminal ganglion contributes to substance P-mediated inflammatory pain显示文摘Inflammatory orofacial pain,in which substance P (SP) plays an important role,is closely related to the cross-talk between trigeminal ganglion (TG) neurons and satellite glial cells (SGCs).SGC activation is emerging as the key mechanism underlying inflammatory pain through different signalling mechanisms,including glial fibrillary acidic protein (GFAP) activation,phosphorylation of mitogen-activated protein kinase (MAPK) signalling pathways,and cytokine upregulation.However,in the TG,the mechanism underlying SP-mediated orofacial pain generated by SGCs is largely unknown.In this study,we investigated whether SP is involved in inflammatory orofacial pain by upregulating interleukin (IL)-1β and tumour necrosis factor (TNF)-α from SGCs,and we explored whether MAPK signalling pathways mediate the pain process.In the present study,complete Freund’s adjuvant (CFA) was injected into the whisker pad of rats to induce an inflammatory model in vivo.SP was administered to SGC cultures in vitro to confirm the effect of SP.Facial expression analysis showed that pre-injection of L703,606 (an NK-1 receptor antagonist),U0126 (an inhibitor of MAPK/extracellular signal-regulated kinase [ERK] kinase [MEK] 1/2),and SB203580 (an inhibitor of P38) into the TG to induce targeted prevention of the activation of the NK-1 receptor and the phosphorylation of MAPKs significantly suppressed CFA-induced inflammatory allodynia.In addition,SP promoted SGC activation,which was proven by increased GFAP,p-MAPKs,IL-1β and TNF-α in SGCs under inflammatory conditions.Moreover,the increase in IL-1β and TNF-α was suppressed by L703,606,U0126 and SB203580 in vivo and in vitro.These present findings suggested that SP,released from TG neurons,activated SGCs through the ERK1/2 and P38 pathways and promoted the production of IL-1β and TNF-α from SGCs,contributing to inflammatory orofacial pain associated with peripheral sensitization. | Yanyan Zhang Ning Song Fei Liu Jiu Lin Mengke Liu Chaolan Huang Daqing Liao Cheng Zhou Hang Wang Jiefei Shen | 2019 | International Journal of Oral Science2019，11，3： | 6 |
| 3 | The Sequence Architecture of Volcanic Basin Fillings-An Example From Xujiaweizi Faulted Depression In Songliao Basin显示文摘The basin filling geometric pattern of volcanic eruptive rocks depends on both of the eruptive locations in a basin and structural styles of fault terraces. It is divided into three types by eruptive locations and occurrences of eruptive rocks, including the pattern of eruption along fault and occurrence (PEAFO), the pattern of eruption on footwall of a fault and occurrence (PEOFO) and the pattern of eruption on hangingwall of fault and occurrence (PEOHO) in Xujiaweizi fault depression of Songliao basin, Northeast of China. Those basin filling patterns of volcanic eruptive rocks are of specific geometric characteristics controlling or affecting sedimentation, geometry of sedimentary body and sequence architecture during a sequence evolution. The study shows that the volcanic rocks developed at different stages of lowstand, transgressive and highstand can give different controls or affects on the sequence architecture. | CHENG Rihui, LIU Wanzhu, SHAN Xuanlong, WANG Pujun (Faculty of Earth Sciences at Jilin University, Changchun, 130061, P.R.China) CHEN Shumin and QU Yongbao (Daqing Petroleum Bureau Prospecting and Exploration Institute, Daqing, 163712, P.R.China) | 2001 | Global Geology2001，6，2： | 3 |
| 4 | PREPARATION,IDENTIFICATION AND INTERFACIAL ACTIVITIES OF PETROLEUM CARBOXYLATE AS SURFACTANT FOR CHEMICAL FLOODING显示文摘Petroleum carboxylate that may be suitable for tertiary oil recovery have been producedinexpensively from the fractions of Daqing crude oil by a two step process.The feed stock was firstoxidized in the vapor phase,followed by reaction of the oxidized products with sodiumhydroxide.Dilute solutions of sodium carboxylates were produced and showultralow(10-2mN/m)interfacial tensions(IFTs)against a variety of hydrocarbons with a widerange of ACN(Alkane Carbon Number).Infrared spectroscopy was used to identify the functionalgroups in the oxidized and the saponified products. | Hong De HUANG Jianghan Petroleum Institute,Jiangling,Hubei,434102You Zhen YANG Ji Xin TANG Cheng Quan HE Rong Ming ZHANG Song Mei ZHANG Daqing Petroleum Institute,Anda,Heilongjiang,151400 | 1993 | Chinese Chemical Letters1993，4，4： | 3 |
| 5 | Geo-location for Ground Target with Multiple Observations Using Unmanned Aerial Vehicle显示文摘In order to improve the target location accuracy of unmanned aerial vehicle(UAV),a novel target location method using multiple observations is proposed.Firstly,the camera intrinsic parameters are calibrated.Then,the weighted least squares estimation is used to improve the localization precision because the traditional crossover method is vulnerable to noise and has low precision.By repeatedly measuring the same target point,a nonlinear observation equation is established and then covered to linear equations using Taylor expansion.The weighted matrix is obtained according to the height of the measurement point and the camera optic axis pointing angle,and then the weighted least squares estimation is used to calculate the target position iteratively.Finally,the effectiveness and robustness of this method is verified by numerical simulation and flight test.The results show that this method can effectively improve the precision of target location. | Xu Cheng He Chenglong Huang Daqing | 2018 | Transactions of Nanjing University of Aeronautics and Astronautics2018，35，5： | 1 |
| 6 | ent -Sauchinone from Saururus chinensis 显示文摘 | Lishu Wang Daqing Zhao Dongyan Cheng | 2008 | Heterocycles2008，75，5： | 1 |
| 7 | Changes of climate and seasonally frozen ground over the past 30 years in Qinghai–Xizang (Tibetan) Plateau, China显示文摘 | Lin Zhao Chien-Lu Ping Daqing Yang Guodong Cheng Yongjian Ding Shiyin Liu | 2004 | Global and Planetary Change2004，，1： | 1 |
| 8 | Formation and structure of sphene/titania composite coatings on titanium formed by a hybrid technique of microarc oxidation and heat-treatment显示文摘 | Su Cheng Daqing Wei Yu Zhou | 2011 | Applied Surface Science2011，257，： | 1 |
| 9 | Characterization and properties of microarc oxidized coatings containing Si, Ca and Na on titanium 显示文摘 | Su cheng Daqing Wei Yu Zhou | 2011 | Ceramics International2011，37，： | 1 |
| 10 | First Beam Commissioning of SSC-Linac as an Injector of SSC显示文摘The construction of the SSC-Linac has made significant progress in 2019.The first beam commissioning of SSC-Linac as an injector of the Separated Sector Cyclotron(SSC)was performed succssfully with ^(40)Ar^(7+) beam and the particle energy of 5.98 MeV/u was obtained at the exit of SSC on December 17,2019. | Du Heng Yin Xuejun Yang Weiqing Li Zhongshan Kong Qiyu Li Xiaoni Yang Shengli Qian Cheng WangHaoning Cong Yan Jin Peng Zhang Ruifeng Han Xiaodong Fu Xin Wang Kai Jing Long Zhang Yong Li Lili Xie Wenjun Xu Xiaowei Wang Shaoming Chen Wenjun Liu Xiaojun Yue Min An Jingrui Zhang Xiang Yan Huaihai Feng Anhui Zhang Shuai Zhang Yongbo Sun Peng Zhu Tieming Sha Xiaoping Xu Jianye Sun Xiaolong Su Xuemin Li Anping Yan Tailai Meng Jun Zhang Wei Wu Junxia Yao Qinggao Yang Yaqing Xu Zhe Sun Liangting Gao Daqing Yuan Youjin Yang Jiancheng Xia Jiawen | 2019 | IMP & HIRFL Annual Report2019，，1： | 0 |
| 11 | Peptidomic Analysis Reveals that Novel Peptide LDP2 Protects Against Hepatic Ischemia/Reperfusion Injury显示文摘Background and Aims:Hepatic ischemia/reperfusion(I/R)injury has become an inevitable issue during liver transplantation,with no effective treatments available.However,peptide drugs provide promising regimens for the treatment of this injury and peptidomics has gradually attracted increasing attention.This study was designed to analyze the spectrum of peptides in injured livers and explore the potential beneficial peptides involved in I/R injury.Methods:C57BL/6 mice were used to establish a liver I/R injury animal model.Changes in peptide profiles in I/R-injured livers were analyzed by mass spectrometry,and the functions of the identified peptides were predicted by bioinformatics.AML12 cells were used to simulate hepatic I/R injury in vitro.After treatment with candidate liver-derived peptides(LDPs)1–10,the cells were collected at various reperfusion times for further study.Results:Our preliminary study demonstrated that 6 h of reperfusion caused the most liver I/R injury.Peptidomic results suggested that 10 down-regulated peptides were most likely to alleviate I/R injury by supporting mitochondrial function.Most importantly,a novel peptide,LDP2,was identified that alleviated I/R injury of AML12 cells.It increased cell viability and reduced the expression of inflammation-and apoptosis-related proteins.In addition,LDP2 inhibited the expression of proteins related to autophagy.Conclusions:Investigation of changes in the profiles of peptides in I/R-injured livers led to identification of a novel peptide,LDP2 with potential function in liver protection by inhibiting inflammation,apoptosis,and autophagy. | Qun Bao Zhengxin Wang Sheng Cheng Jin Zhang Qiuli Liu Yunpeng Zhang Daqing Cheng Xirong Guo Xingyun Wang Bo Han Peng Sun | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 0 |
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