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| 1 | Micromolded honeycomb scaffold design to support the generation of a bilayered RPE and photoreceptor cell construct显示文摘Age-related macular degeneration(AMD)causes blindness due to loss of retinal pigment epithelium(RPE)and photoreceptors(PRs),which comprise the two outermost layers of the retina.Given the small size of the macula and the importance of direct contact between RPE and PRs,the use of scaffolds for targeted reconstruction of the outer retina in later stage AMD and other macular dystrophies is particularly attractive.We developed microfabricated,honeycomb-patterned,biodegradable poly(glycerol sebacate)(PGS)scaffolds to deliver organized,adjacent layers of RPE and PRs to the subretinal space.Furthermore,an optimized process was developed to photocure PGS,shortening scaffold production time from days to minutes.The resulting scaffolds robustly supported the seeding of human pluripotent stem cell-derived RPE and PRs,either separately or as a dual celllayered construct.These advanced,economical,and versatile scaffolds can accelerate retinal cell transplantation efforts and benefit patients with AMD and other retinal degenerative diseases. | In-Kyu Lee Ruosen Xie Agustin Luz-Madrigal Seunghwan Min Jingcheng Zhu Jiahe Jin Kimberly L.Edwards M.Joseph Phillips Allison L.Ludwig David M.Gamm Shaoqin Gong Zhenqiang Ma | 2023 | Bioactive Materials2023,,12: | 1 |
| 2 | Persistence and challenges to filial piety and informal support of older persons in a modern Chinese society显示文摘 | Anita Ching Ying Ng David R. Phillips William Keng-mun Lee | 2002 | Journal of Aging Studies2002,,2: | 1 |
| 3 | General Application of Raman Spectros- copy for the Determination of Level of Application in Modified Starches显示文摘 | David Lee Phillips | 1999 | Cereal Chemistry1999,,76: | 1 |
| 4 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria显示文摘 | S. Nahum Goldberg Clement J. Grassi John F. Cardella J. William Charboneau Gerald D. Dodd Damian E. Dupuy Debra A. Gervais Alice R. Gillams Robert A. Kane Fred T. Lee Tito Livraghi John McGahan David A. Phillips Hyunchul Rhim Stuart G. Silverman Luigi Sol | 2009 | Journal of Vascular and Interventional Radiology2009,,7: | 1 |
| 5 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria显示文摘 | S. Nahum Goldberg Clement J. Grassi John F. Cardella J. William Charboneau Gerald D. Dodd Damian E. Dupuy Debra Gervais Alice R. Gillams Robert A. Kane Fred T. Lee Tito Livraghi John McGahan David A. Phillips Hyunchul Rhim Stuart G. Silverman | 2005 | Journal of Vascular and Interventional Radiology2005,,6: | 1 |
| 6 | Association Between Donor-Specific Antibodies and Acute Rejection and Resolution in Small Bowel and Multivisceral Transplantation显示文摘 | Hsin-Lin Tsai Eddie R. Island Jei-Wen Chang Ignacio Gonzalez-Pinto Panagiotis Tryphonopoulos Seigo Nishida Gennaro Selvaggi Akin Tekin Jang Moon David Levi E. Steve Woodle Phillip Ruiz Debbie Weppler Oscar K.S. Lee Andreas G. Tzakis | 2011 | Transplantation2011,,6: | 1 |
| 7 | Comprehensive neurocognitive assessment of patients with anorexia nervosa显示文摘AIM:To utilise a comprehensive cognitive battery to gain a better understanding of cognitive performance in anorexia nervosa(AN).METHODS:Twenty-six individuals with AN and 27 healthy control participants matched for age,gender and premorbid intelligence,participated in the study.A standard cognitive battery,the Measurement and Treatment Research to Improve Cognition in Schizophrenia Consensus Cognitive Battery,was used to investigate performance on seven cognitive domains with the use of 10 different tasks:speed of processing[Brief Assessment Of Cognition In Schizophrenia:Symbol Coding,Category Fluency:Animal Naming(Fluency)and Trail Making Test:Part A],attention/vigilance[Continuous Performance Test-Identical Pairs(CPT-IP)],working memory[Wechsler Memory Scale(WMS?-Ⅲ):Spatial Span,and Letter-Number Span(LNS)],verbal learning[Hopkins Verbal Learning Test-Revised],visual learning[Brief Visuospatial Memory Test-Revised],reasoning and problem solving[Neuropsychological Assessment Battery:Mazes],and social cognition[Mayer-Salovey-Caruso Emotional Intelligence Test:Managing Emotions].Statistical analyses involved the use of multivariate and univariate analyses of variance.RESULTS:Analyses conducted on the cognitive domain scores revealed no overall significant difference between groups nor any interaction between group and domain score[F(1,45)=0.73,P=0.649].Analyses conducted on each of the specific tasks within the cognitive domains revealed significantly slower reaction times for false alarm responses on the CPT-IP task in AN[F(1,51)=12.80,P<0.01,Cohen’s d=0.982]and a trend towards poorer performance in AN on the backward component of the WMS?-ⅢSpatial Span task[F(1,51)=5.88,P=0.02,Cohen’s d=-0.665].The finding of slower reaction times of false alarm responses is,however,limited due to the small number of false alarm responses for either group.CONCLUSION:The findings are discussed in terms of poorer capacity to manipulate and process visuospatial material in AN. | Andrea Phillipou Caroline Gurvich David Jonathan Castle Larry Allen Abel Susan Lee Rossell | 2015 | World Journal of Psychiatry2015,5,4: | 1 |
| 8 | General Application of Raman Spectroscopy for the Determination of Level of Application in Modified Starches显示文摘 | David lee Phillips | 1999 | Cereal Chemistry1999,,76: | 1 |
| 9 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria显示文摘 | S. Nahum Goldberg Clement J. Grassi John F. Cardella J. William Charboneau Gerald D. Dodd Damian E. Dupuy Debra A. Gervais Alice R. Gillams Robert A. Kane Fred T. Lee Tito Livraghi John McGahan David A. Phillips Hyunchul Rhim Stuart G. Silverman Luigi Sol | 2009 | Journal of Vascular and Interventional Radiology2009,,7: | 1 |
| 10 | General Application of Raman Spectroscopy for the Determination of Level of Application in Modified Starches 显示文摘 | David Lee Phillips | 1999 | Cereal Chemistry1999,,76: | 1 |
| 11 | General Application of Raman Spectroscopy for the Determination of Level of Acetylation in Modified Starches显示文摘 | David Lee Phillips | 1999 | Cereal Chemistry1999,76,: | 1 |
| 12 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria显示文摘 | S. Nahum Goldberg Clement J. Grassi John F. Cardella J. William Charboneau Gerald D. Dodd Damian E. Dupuy Debra A. Gervais Alice R. Gillams Robert A. Kane Fred T. Lee Tito Livraghi John McGahan David A. Phillips Hyunchul Rhim Stuart G. Silverman Luigi Sol | 2009 | Journal of Vascular and Interventional Radiology2009,,7: | 1 |
| 13 | The diagnosis and reproductive outcome after surgical treatment of the complete septate uterus, duplicated cervix and vaginal septum显示文摘 | Phillip E Patton Miles J Novy David M Lee Lee R Hickok | 2004 | American Journal of Obstetrics and Gynecology2004,,6: | 1 |
| 14 | Raman spectroscopic study of globulin from Phaseolus angularis (red bean) 显示文摘 | Guangtao Meng Ching Yung Ma David Lee Phillips | 2003 | Food Chemistry2003,81,: | 1 |
| 15 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria显示文摘 | S. Nahum Goldberg Clement J. Grassi John F. Cardella J. William Charboneau Gerald D. Dodd Damian E. Dupuy Debra Gervais Alice R. Gillams Robert A. Kane Fred T. Lee Tito Livraghi John McGahan David A. Phillips Hyunchul Rhim Stuart G. Silverman | 2005 | Journal of Vascular and Interventional Radiology2005,,6: | 1 |
| 16 | Electrocatalytic oxidation of formic acid by Pt/Co nanoparticles显示文摘 | Ning Chi Kwong-Yu Chan David Lee Phillips | 2001 | Catalysis Letters (-)2001,,1: | 1 |
| 17 | Laparoscopic cholecystectomy: first, do no harm; second, take care of bile duct stones显示文摘 | George Berci John Hunter Leon Morgenstern Maurice Arregui Michael Brunt Brandon Carroll Michael Edye David Fermelia George Ferzli Frederick Greene Joseph Petelin Edward Phillips Jeffrey Ponsky Harry Sax Steven Schwaitzberg Nathaniel Soper Lee Swanstrom Wi | 2013 | Surgical Endoscopy2013,,4: | 1 |
| 18 | A New Measure of Quality of Work Life (QWL) Based on Need Satisfaction and Spillover Theories显示文摘 | M. Joseph Sirgy David Efraty Phillip Siegel Dong-Jin Lee | 2001 | Social Indicators Research2001,,3: | 1 |
| 19 | Synthesis,Structures,and Chiroptical Properties of NBN-Doped Helicenes with Boron Atoms in the Inner Rims显示文摘The precise synthesis of helicenes with topologically defined length and specific heteroatomic perturbation in the screw-like conjugated skeletons plays an emerging role in the manipulation of chiral materials.Facile,selective,and programmable routes to helicenes or heterohelicenes are highly desirable yet challenging for structure-chiroptical property relationship studies.Herein,we report the synthesis and characterization of NBN-doped helicenes with boron atoms in the inner rims,enabled by the highly regioselective one-pot borylation of rationally designed precursors with,namely,fold-in or pan-out manner.The incorporation of nonbonded boron and nitrogen atoms resulted in narrow-band emission and improved optical properties for the single-stranded carbon helix.In addition,numbers and arrangement modes of fused six-membered rings have distinct effects on configurational stability and chiroptical properties,revealing that BN-[6]H with strong circular dichroism is a promising candidate for chiral sensors.The combination of experimental and theoretical studies on these helical structures might provide insights into the design of helically chiral small-molecule-based sensors or emitters. | Weiwen Zhuang Yujian Liu Ziqi Deng Yu Guo Philip C.Y.Chow David Lee Phillips Wei Jiang Zhaohui Wang Junzhi Liu | 2024 | Precision Chemistry2024,2,1: | 0 |
| 20 | Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn’s disease显示文摘BACKGROUND Evidence suggests inflammatory mesenteric fat is involved in post-operative recurrence(POR)of Crohn’s disease(CD).However,its prognostic value is INTRODUCTION Crohn’s disease(CD)is a debilitating chronic immune-mediated inflammatory disease(IMID)of the gastrointestinal tract that is increasing in incidence and prevalence globally[1].CD patients often undergo surgery for disease-related complic-ations and/or medically refractory disease.Unfortunately,surgery is not curative,and many patients develop post-operative recurrence(POR)of CD with a significant proportion eventually requiring additional surgeries.With advances in early detection and therapeutics,the contemporary 10-year risk of surgery has improved from 50%to 26%,but the risk of recurrent surgery has remained unchanged at 30%,suggesting a need to improve post-operative management strategies[2].Presently,there are two accepted strategies to mitigate POR,but each have potential limitations.Firstly,patients start early post-operative pharmacologic prophylaxis within 4-6 wk after surgery.This strategy can potentially overtreat a subset of patient who may not develop long-term disease recurrence off therapy.Consequently,these patients are at risk of medication-related adverse events and the direct and indirect costs associated with therapy with little or no benefit[3].The second strategy is performing early colonoscopy within 6-12 months after surgery and escalating therapy based on FOOTNOTES Author contributions:Gu P is the guarantor of the article and was involved in concept and design,data collection,statistical analysis,drafting of manuscript,and final approval of manuscript;Dube S and Choi SY were involved in statistical analysis,drafting of the manuscript,and final approval of manuscript;Gellada N,Win S,Lee YJ and Yang S were involved in the data collection,drafting of the manuscript,and final approval of manuscript;Haritunians T and Li D were involved in data analysis and interpretation,drafting of manuscript and final approval of manuscript;Melmed GY,Yarur AJ,Fleshner P,Kallman C and Devkota S were involved in study concept and design,data interpretation,drafting of manuscript and final approval of manuscript;Vasiliauskas EA,Bonthala N,Syal G,Ziring D and Targan SR were involved in data interpretation,drafting of manuscript and final approval of manuscript;Rabizadeh S was involved in study concept and design,drafting of manuscript and final approval of manuscript;McGovern DPB was involved in concept and design,statistical analysis,drafting of manuscript and final approval of manuscript. | Phillip Gu Shishir Dube Norman Gellada So Yung Choi Susan Win Yoo Jin Lee Shaohong Yang Talin Haritunians Gil Y Melmed Eric A Vasiliauskas Niru Bonthala Gaurav Syal Andres J Yarur David Ziring Shervin Rabizadeh Phillip Fleshner Cindy Kallman Suzanne Devkota Stephan R Targan Dalin Li Dermot PB McGovern | 2024 | World Journal of Gastrointestinal Surgery2024,16,3: | 0 |