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26篇 您的检索式:作者名="Dean DB"
    题名 作者 年代 出处 被引量
1Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft显示文摘Lorenz RR Dean RL Hurley DB 0,,3:1
2Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograf显示文摘Lorenz RR Dean RL Hurley DB 2003Laryngoscope2003,113,3:1
3Differentiation-dependent expression of obese gene by preadipocytes and adipocytes in primary cultures of porcine stromal-vascular ceils 显示文摘Chen X Hausman DB Dean RG 1997Biochem Biophys Acta1997,1359,:1
4Late salvage of failed open reduction and internal fixation of posterior wall fractures of the acetabulum显示文摘Dean DB Moed BR 2009J Orthop Trauma2009,23,3:1
5Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft显示文摘Lorenz RR Dean RL Hurley DB 2003Laryngoscope2003,113,3:1
6Endoscopic reconstruction ofanterior and middle cranial fossa defects using acellular dermal allograft显示文摘Loernz RR Dean RL Hurley DB 2003Laryngoscope2003,113,3:1
7Late salvage of failed open reduction and internal fixation of posterior wall fractures of the acetabulum显示文摘Dean DB Moed BR 2009J Orthop Trauma2009,23,3:1
8Role of bone mor- phogenetic proteins and their antagonists in healing of bone fracture显示文摘Dean DB Watson JT Moed BR 2009Front Biosci2009,32,14:1
9Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular demal allograft显示文摘Lorenz RR Dean RL Hurley DB 2003Laryngoscope2003,113,3:1
10Endoscopic reconstruc-tion of anterior and middle cranial fossa defects using a-cellular demal allograft显示文摘Lorenz RR Dean RL Hurley DB 0,,03:1
11Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft显示文摘Lorenz RR Dean RL Hurley DB 2003Loryngoseope2003,113,3:1
12Late salvage of failed open reduction and internal fixation of posterior wall fractures of the acetabulum显示文摘Dean DB Moed BR 0,,03:1
13Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft显示文摘Lorenz RR Dean RL Hurley DB 2003Laryngoscope2003,113,3:1
14Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft显示文摘Lorenz RR Dean RL Hurley DB 0,,03:1
15Taking the lag out of jet lag through model-based schedule design显示文摘Dean DA 2nd Forger DB Klerman EB 2009PLoS Comput Biol2009,5,10:1
16CDK4/6 inhi-bition antagonizes the cytotoxic response to anthracycline therapy显示文摘McClendon AK Dean JL Rivadeneira DB 2012Cell Cycle2012,11,14:1
17Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft显示文摘Lorenz RR Dean RL Hurley DB 2003Laryngoscope2003,113,3:1
18Endoscopic reconstruction of anterior and middle cranial fossa defects using acellular dermal allograft 显示文摘Lorenz RR Dean RL Hurley DB et ol 2003Laryngoscope2003,113,3:1
19Role of material surfaces in regulating bone and cartilage cellresponse显示文摘Boyan DB Hunnert TW Dean DD 0,,02:1
20Neutrophil kinetics and function after major trauma:A systematic review显示文摘BACKGROUND Immune dysfunction following major traumatic injury is complex and strongly associated with significant morbidity and mortality through the development of multiple organ dysfunction syndrome(MODS),persistent inflammation,immunosuppression,and catabolism syndrome and sepsis.Neutrophils are thought to be a pivotal mediator in the development of immune dysfunction.AIM To provide a review with a systematic approach of the recent literature describing neutrophil kinetics and functional changes after major trauma in humans and discuss hypotheses as to the mechanisms of the observed neutrophil dysfunction in this setting.METHODS Medline,Embase and PubMed were searched on January 15,2021.Papers were screened by two reviewers and those included had their reference list hand searched for additional papers of interest.Inclusion criteria were adults>18 years old,with an injury severity score>12 requiring admission to an intensive care unit.Papers that analysed major trauma patients as a subgroup were included.RESULTS Of 107 papers screened,48 were included in the review.Data were heterogeneous and most studies had a moderate to significant risk of bias owing to their observational nature and small sample sizes.Key findings included a persistently elevated neutrophil count,stereotyped alterations in cell-surface markers of activation,and the elaboration of heterogeneous and immunosuppressive populations of cells in the circulation.Some of these changes correlate with clinical outcomes such as MODS and secondary infection.Neutrophil phenotype remains a promising avenue for the development of predictive markers for immune dysfunction.CONCLUSION Understanding of neutrophil phenotypes after traumatic injury is expanding.A greater emphasis on incorporating functional and clinically significant markers,greater uniformity in study design and assessment of extravasated neutrophils may facilitate risk stratification in patients affected by major trauma.Liam DB Finlay Andrew Conway Morris Adam M Deane Alexander JT Wood 2021World Journal of Critical Care Medicine2021,10,5:1
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