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| 1 | Adaptive immune-genetic algorithm for global optimization to multivariable function显示文摘An adaptive immune- genetic algorithm (ALGA) is proposed to avoid premature convergence and guarantee the diversity of the population.Rapid immune response (secondary response),adaptive mutation and density operators in the AIGA are emphatically designed to improve the searching ability,greatly increase the converging speed,and decrease locating the local maxima due to the premature convergence.The simulation results obtained from the global optimization to four multivariable and multi-extreme functions show that AIGA converges rapidly,guarantees the diversity,stability and good searching ability. | Dai Yongshou Li Yuanyuan Wei Lei Wang Junling Zheng Deling | 2007 | Journal of Systems Engineering and Electronics2007，18，3： | 9 |
| 2 | Generation and characterization of stable pig pregastrulation epiblast stem cell lines显示文摘Pig epiblast-derived pluripotent stem cells are considered to have great potential and broad prospects for human therapeutic model developme nt and livestock breeding.Despite on going attempts since the 1990s,no stably defined pig epiblast-derived stem cell line has bee n established.Here,guided by in sights from a large-scale sin gle-cell tran scriptome an alysis of pig embryos from embryonic day(E)0 to E14,specifically,the tracing of pluripotency changes during epiblast development,we developed an in vitro culture medium for establishing and maintaining stable pluripotent stem cell lines from pig E10 pregastrulation epiblasts(pgEpiSCs).Enabled by chemical inhibition of WNT-related signaling in combination with growth factors in the FGF/ERK,JAK/STAT3,and Activin/Nodal pathways,pgEpiSCs maintain their pluripotency transcriptome features,similar to those of E10 epiblast cells,and normal karyotypes after more than 240 passages and have the potential to differentiate into three germ layers.Strikingly,ultradeep in situ Hi-C analysis revealed functional impacts of chromatin 3D-spatial associations on the transcriptional regulation of pluripote ncy marker genes in pgEpiSCs.I n practice,we con firmed that pgEpiSCs readily tolerate at least three rounds of successive gene editi ng and gene rated cloned gen e-edited live piglets.Our findings deliver on the long-a nticipated promise of pig pluripote nt stem cells and open new avenues for biological research,animal husbandry,and regenerative biomedicine. | Minglei Zhi Jinying Zhang Qianzi Tang Dawei Yu Shuai Gao Dengfeng Gao Pengliang Liu Jianxiong Guo Tang Hai Jie Gao Suying Cao Zimo Zhao Chongyang Li Xiaogang Weng Mengnan He Tianzhi Chen Yingjie Wang Keren Long Deling Jiao Guanglei Li Jiaman Zhang Yan Liu Yu Lin Daxin Pang Qianqian Zhu Naixin Chen Jingjing Huang Xinze Chen Yixuan Yao Jingcang Yang Zicong Xie Xianya Huang Mengxin Liu Ran Zhang Qiuyan Li Yiliang Miao Jianhui Tian Xingxu Huang Hongsheng Ouyang Bofeng Liu Wei Xie Qi Zhou Zhonghua Liu Caihong Zheng Mingzhou Li Jianyong Han | 2022 | Cell Research2022，32，4： | 3 |
| 3 | Simulation and experimental study of a random neutron analyzing system with (252)~Cf neutron source显示文摘Experiments were performed on a high-speed online random neutron analyzing system (HORNA system) with a 252Cf neutron source (up to 1 GHz sampling rate and 3 input data channel),to obtain timeand frequency dependent signatures which are sensitive to changes in the composition,fissile mass and configuration of the fissile assembly.The data were acquired by three high-speed synchronized acquisition cards at different detector angles,source-detector distances and block sizes.According to the relationship between 252Cf source and the ratio of power spectral density,Rpsd,all the signatures were calculated and analyzed using correlation and periodogram methods.Based on the results,the simulated autocorrelation functions were utilized for identifying different fissile mass with Elman neural network.The experimental results show that the Rpsd almost remains at constant amplitude in frequency range of 0-100 MHz,and is only related to the angle and source-detector distance.The trained Elman neural network is able to distinguish the characteristics of autocorrelation function and identify different fissile mass.The average identification rate reached 90% with high robustness. | FENG Peng LIU Siyuan WEI Biao JIN Jing MI Deling | 2011 | Nuclear Science and Techniques2011，22，1： | 3 |
| 4 | Beta-arrestin 2 modulates resveratrol-induced apoptosis and regulation of Akt/GSK3β pathways显示文摘 | Xiuli Sun Yi Zhang Jianliu Wang Lihui Wei Hui Li Gregory Hanley Miaoqing Zhao Yi Li Deling Yin | 2010 | BBA - General Subjects2010，，9： | 1 |
| 5 | Extended pancreatoduodenectomy with portal vein and inferior vena cava resection and reconstruction combined with sorafenib for hepatoid carcinoma of the pancreas:a strategy of superextended surgery combined with targeted therapy显示文摘Hepatoid carcinoma of the pancreas(HCP)is an extremely rare pancreatic cancer resembling hepatocellular carcinoma,a type of liver cancer(1).Most reports have shown that it has an aggressive behavior and is associated with early metastasis.There is no standardized treatment for HCP due to its rarity,and the limited number of cases reported in the literature(2,3).However,treatment options for this type of rare cancer include surgery,chemotherapy,and radiation therapy,depending on the stage of the cancer.Nevertheless,the prognosis of HCP is poor. | Deling Wei Banghao Xu Hai Zhu Jilong Wang Zongrui Jin Weitao Chen Jianyong Zhang Zhujing Lan Keyu Huang Ling Zhang Tingting Lu Ni Fang Ya Guo Tao Peng Minhao Peng Zhang Wen | 2023 | Hepatobiliary Surgery and Nutrition2023，12，4： | 0 |
| 6 | Reciprocal interaction between vascular niche and sweat gland promotes sweat gland regeneration显示文摘The incorporation of vasculature is known to be effective in tissue or organ functional regeneration.However,a vague understanding of the interaction between epidermal appendages and their vascular niches is a foremost obstacle to obtaining sweat gland(SG)-specific vasculature units.Here,we map their precise anatomical con-nections and report that the interplay between SG cells(SGCs)and the surrounding vascular niche is key for glandular development and homeostasis maintenance.To replicate this interplay in vitro,we used three-dimensional(3D)bioprinting to generate reproducible SGC spheroids from differentiated adipose-derived mesenchymal stem cells(ADSCs).With dermal microvascular endothelial cells(DMECs),sacrificial templates made from poly(ε-caprolactone)(PCL)were fabricated to pattern the vascular niche.This interplay model promoted physiologically relevant vascularized glandular morphogenesis in vitro and in vivo.We identified a reciprocal regulatory mechanism for promoting SGs regeneration via contact-independent cell communication and direct cell-cell interactions between SGs and the vasculature.We envision the successful use of our approach for vascularized organ regeneration in the near future. | Xingyu Yuan Xianlan Duan Enhejirigala Zhao Li Bin Yao Wei Song Yuzhen Wang Yi Kong Shijun Zhu Fanliang Zhang Liting Liang Mengde Zhang Chao Zhang Deling Kong Meifeng Zhu Sha Huang Xiaobing Fu | 2023 | Bioactive Materials2023，，3： | 0 |
| 7 | Improving Generalization of Fuzzy Neural Network显示文摘Explores the generalization error of fuzzy neural network, analyzes the reason for occurrence and presents the equation of calculating error by the confidence interval approach. In addition, a generalization error transfering(GET) method of improving the generalization error is proposed. The simulation experimental results of heating furnance show that the GET scheme is efficient. | ZHENG Deling LI Qing FANG Wei(Information Engineering School, USTB, Beijing 100083, China) (China National Electronics Imp. &Exp. Beijing Co.) | 1997 | International Journal of Minerals,Metallurgy and Materials1997，11，2： | 0 |
| 8 | Theory,Method and Application of a State Recognition Based on Theory of Evidence显示文摘A new method of state recognition based on the theory of evidence was proposed. By this method, the plausible function which the sample awaiting recognition belongs to each category can be obtained through distance function. For the marginal samples,two or a batch of evidences can be combined and a new plausible function can be obtained by new evidence. Then the categories of samples can be determined according to plausibility function. This method provides a beder reasoning framework. The result proves the rate of recoghition correctness. | Deling Zheng Xinbei Tang Wei Fang (Information Engineering School, University of Science and Technology Beijing, Beijing 100083, China)(Peat Marwick Huazhen CPA Firm, 100020, China) | 1999 | International Journal of Minerals,Metallurgy and Materials1999，13，1： | 0 |
| 9 | Application of Gray Linear Programming in Sintering Mixing Calculation显示文摘The mixing calculation cannot be restrained by the quantity of return mines. In order to solve this problem, a method that the sintering mixing proportion is optimized by gray linear programming is presented based on the gray system theory and optimal theory. By using this method, the quality of sintering mines is improved and the energy consumption is reduced. | Deling Zheng, Zhijiang Zhao, Wei Fang, Tong Fang ( Information Engineering School, University of Science and Technology Beijing, Beijing 100083, China. Tangshan Iron and Steel Group Corp., Tangshan 063000, China Peat Marwick Huazhen CPA Firm, Beijing 10 | 2000 | International Journal of Minerals,Metallurgy and Materials2000，14，4： | 0 |
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