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244篇 您的检索式:作者名="Dichgans M"
    题名 作者 年代 出处 被引量
1皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 2016国际脑血管病杂志2016,24,6:18
2利用抗高血压药相关的遗传变异发现其潜在的功效和副作用显示文摘通过研究药物靶蛋白基因的自然变异可以了解药物的功效。本研究旨在利用这种方法探索抗高血压药的潜在副作用和再利用潜力。研究者首先确定了血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、β受体阻滞剂和钙拮抗剂的合适代表基因。刘青(译) 叶鹏(校) Gill D Georgakis MK Koskeridis F Jiang L Feng Q Wei WQ Theodoratou E Elliott P Denny JC Malik R Evangelou E Dehghan A Dichgans M Tzoulaki I 2019中华高血压杂志2019,0,9:3
3Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL显示文摘Dichgans M Markus HS Salloway S 2008Lancet Neurol2008,7,4:1
4Donepezil in patients with subcortical vascular cognitive impairment:a randomised double-blind trial in CADASIL 显示文摘Dichgans M Markus HS Salloway S 2008Lancet Neurol2008,7,4:1
5Mutation in the neuro-nal voltage-gated sodium channel SCN1A in familial hemiplegicmigraine显示文摘Dichgans M Freilinger T Eckstein G 2005Lancet2005,366,9483:1
6Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging 显示文摘Wardlaw JM Smith C Dichgans M 2013Lancet Neurol2013,12,5:1
7Cholesterol and Alzheimer's dis- ease : is there a link 显示文摘Simons M Keller P Dichgans J 20019 Neurology2001,57,6:1
8SELEDO: a 5-year long term trial on the effect of selegine in early Parkinsonian patients treated with levodopa显示文摘Przuntek H Conrad B Dichgans M 1999Eur J Neurol1999,6,2:1
9The phenotypic spectrum of CADASIL:clinical findings in 102 cases显示文摘Dichgans M Mayer M Uttner I 1998Ann Neurol1998,44,4:1
10Cerebral autosomal dominant arteriopathy with subcor-tical infarcts and leukoencephalopathy: phenotypic and mutational spectrum显示文摘Dichgans M 2002Neurol Sci2002,203,:1
11Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging 显示文摘Wardlaw JM Smith C Dichgans M 2013Lancet Neurol2013,12,:1
12Pontine MRI hyperintensities ('the cross sign') are not pathognomonic for multiple system atrophy (MSA)显示文摘 Skalej M Dichgans J 2001Mov Disord2001,16,:1
13Cerebral microbleeds in CADASIL: a gradient-echo magnetic resonance imaging and autopsy study显示文摘Dichgans M Holtmannspotter M Herzog J 2002Stroke2002,33,1:1
14Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging显示文摘Wardlaw J M Smith C Dichgans M 2013Lancet Neurol2013,12,5:1
15Mechanisms of spo- radic cerebral small vessel disease: insights from neuroimaging 显示文摘WARDLAW JM SMITH C DICHGANS M 2013Lancet Neurol2013,12,5:1
16Genetics of ischaemic stroke 显示文摘Dichgans M 2007Lancet Neurol2007,6,2:1
17Genetics of ischaemic stroke显示文摘Dichgans M 2007Lancet Neurol2007,6,:1
18Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy:phenotypic and mutational spectrum 显示文摘Dichgans M 2002J Neurol Sci2002,204,:1
19Manifestation of Hashimoto's encephalopathy years before onset of thyroid disease显示文摘Peschen-Rosin R Schabet M Dichgans J 0,,02:1
20CADASIL:a monogenic condition causing stroke and subcortical vascular dementia显示文摘Dichgans M 0,,2:1
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