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| 1 | Study on photocatalytic oxidation for determination of the low chemical oxygen demand using a nano-TiO2-Ce(SO4 )2 coexisted system显示文摘 | CHAI Yi-hao DING Hong-chun ZHANG Zhonghai | 2006 | Talanta2006，68，： | 1 |
| 2 | A high-linking algorithm for sign-changing solutions of semilinear elliptic equations显示文摘 | ZHONGHAI DING DAVID COSTA GOONG CHEN | 1999 | Nonlinear Anal1999，38，： | 1 |
| 3 | A high-linking algorithm for sign-changing solution of semilinear elliptic equation显示文摘 | DING Zhonghai COSTA David CHEN Goong | 1999 | Nonlinear Anal1999，38，2： | 1 |
| 4 | A high-linking algorithm for sign-changing solutions of semilinear elliptic equations显示文摘 | ZHONGHAI DING DAVID COSTA GOONG CHEN | 1999 | Nonlinear Anal1999，38，： | 1 |
| 5 | Nonlinear periodic oscillations in a suspension bridge system under periodic external aerodynamic forces显示文摘 | DING Zhonghai | 2002 | Nonlinear Analysis2002，49，： | 1 |
| 6 | A bare-bones multi-objective particle swarm optimization algorithm for environmental/economic dispatch显示文摘 | Zhang Yong Gong Dun wei Ding Zhonghai | 2012 | Information Sciences2012，19，21： | 1 |
| 7 | Study on photocatalytic oxidation for determination of the low chemical oxygen demand using a nano-TiO2-Ce(SO4)2 codexisted system显示文摘 | Yihao Chai Hongchun Ding Zhonghai Zhang | 2006 | Talanta2006，68，： | 1 |
| 8 | Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson’s disease显示文摘Background:Parkinson’s disease(PD)is a neurodegenerative disease characterized by intraneuronal Lewy Body(LB)aggregates composed of misfolded alpha-synuclein(α-syn).The spread of misfoldedα-syn follows a typical pattern:starting in the olfactory bulb(OB)and the gut,this pathology is followed by the progressive invasion of misfoldedα-syn to the posterior part of the brain.It is unknown whether the administration of human mutant alpha-synuclein(hm-α-syn,a human mutation which occurs in familial PD)into the OB of rats would trigger similarα-syn propagation and subsequently cause pathological changes in broader brain fields associated to PD and establish an animal model of prodromal PD.Methods:hm-α-syn was overexpressed in the OB of rats with an AAV injection.Then motor and non-motor symptoms of the SD rats were tested in different behavioral tasks following the AAV injection.In follow-up studies,pathological mechanisms ofα-syn spread were explored at the histological,biochemical and micro-structure levels.Results:The experimental results indicated that hm-α-syn was overexpressed in the OB 3 weeks after the AAV injection.1)overexpression of the Hm-α-syn in the OB by the AAV injection could transfer to wider adjacent fields beyond the monosynaptic scope.2)The number of tyrosine hydroxylase positive cells body and fibers was decreased in the substantia nigra(SN)12 weeks after AAV injection.This was consistent with decreased levels of the DA neurotransmitter.Importantly,behavioral dysfunctions were found that included olfactory impairment after 3 weeks,motor ability impairment and decreased muscular coordination on a rotarod 6 weeks after the AAV injection.3)The morphological level studies found that the Golgi staining revealed the number of neuronal branches and synapses in the OB,prefrontal cortex(PFC),hippocampus(Hip)and striatum caudate putamen(CPU)were decreased.4)phosphorylatedα-syn,at Ser-129(pSer129),was found to be increased in hm-α-syn injected animals in comparison to controls that overexpressed GFP alone,which was also found in the most of LB stained by the thioflavine S(ThS)in the SN field.5)A marker of autophagy(LC3B)was increased in serval fields,which was colacolizated with a marker of apoptosis in the SN field.Conclusions:These results demonstrate that expression of exogenous mutantα-syn in the OB induces pathological changes in the sensitive brain fields by transferring pathogenicα-syn to adjacent fields.This method may be useful for establishing an animal model of prodromal PD. | Haichen Niu Lingyu Shen Tongzhou Li Chao Ren Sheng Ding Lei Wang Zhonghai Zhang Xiaoyu Liu Qiang Zhang Deqin Geng Xiujuan Wu Haiying Li | 2018 | Translational Neurodegeneration2018，7，1： | 0 |
| 9 | Retraction Note: Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson’s disease显示文摘Retraction Note:Translational Neurodegeneration(2018)7:25 http://gffzzd3cc09b8251d45dfspn5uxf5op50p656u.ffgz.tsg.suse.edu.cn/10.1186/s40035-018-0128-6 The Editor-in-Chief has retracted this article.After pub-lication,concerns were raised regarding image overlap across various panels in Fig.8.The authors have stated that incorrect images were used,but have been unable to provide the full raw data.Additionally,the authors could not justify the anesthetic protocol used for rat stereotaxic surgery.The Editor-in-Chief therefore no longer has con-fidence in the presented data and ethics of this article.Author Haichen Niu has stated on behalf of all co-authors that they agree to this retraction. | Haichen Niu Lingyu Shen Tongzhou Li Chao Ren Sheng Ding Lei Wang Zhonghai Zhang Xiaoyu Liu Qiang Zhang Deqin Geng Xiujuan Wu Haiying Li | 2022 | Translational Neurodegeneration2022，11，1： | 0 |
| 10 | Late Jurassic adakitic ore-bearing granodiorite porphyry intrusions in the Xiaokele porphyry Cu(–Mo)deposit,Northeast China:implications for petrogenesis and tectonic setting显示文摘The Xiaokele Cu(–Mo)deposit is a recently discovered porphyry deposit in the northern Great Xing’an Range(GXR)of northeast China.The ore bodies in this deposit are mainly hosted within granodiorite porphyry intrusions.Potassic,phyllic,and propylitic alteration zones develop from center to edge.In this paper,we present zircon LA–ICP–MS U–Pb ages,zircon Hf isotopic compositions,and whole-rock geochemistry of the ore-bearing granodiorite porphyries from the Xiaokele Cu(–Mo)deposit.Zircon U–Pb dating suggests that the Xiaokele granodiorite porphyries were emplaced at 148.8±1.1 Ma(weighted-mean age;n=14).The Xiaokele granodiorite porphyries display high SiO2,Al2O3,Sr,and Sr/Y,low K2O/Na2O,MgO,Yb,and Y,belonging to high-SiO2 adakites produced by partial melting of the subducted oceanic slab.Marine sediments were involved in the magma source of the Xiaokele granodiorite porphyries,as indicated by enriched Sr–Nd isotopic compositions(eNd(-t)=-1.17–-0.27),low positive zircon eHf(t)values(0.4–2.2),and high Th contents(4.06–5.20).The adakitic magma subsequently interacted with the mantle peridotites during ascent through the mantle wedge.The Xiaokele granodiorite porphyries were derived from slab melting during the southward subduction of the Mongol–Okhotsk Ocean. | Yonggang Sun Bile Li Zhonghai Zhao Qingfeng Ding Fanbo Meng Xusheng Chen Ye Qian Yujin Li | 2021 | Acta Geochimica2021，40，5： | 0 |
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