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| 1 | Component analysis of Chinese medicine and advances in fuming-washing therapy for knee osteoarthritis via unsupervised data mining methods显示文摘OBJECTIVE: To analyze the component law of Chinese medicines in fuming-washing therapy for knee osteoarthritis(KOA), and develop new fuming-washing prescriptions for KOA through unsupervised data mining methods.METHODS: Chinese medicine recipes for fuming-washing therapy for KOA were collected and recorded in a database. The correlation coefficient among herbs, core combinations of herbs, andnew prescriptions were analyzed using modified mutual information, complex system entropy cluster, and unsupervised hierarchical clustering, respectively.RESULTS: Based on analysis of 345 Chinese medicine recipes for fuming-washing therapy, 68 herbs occurred frequently, 33 herb pairs occurred frequently, and 12 core combinations were found.Five new fuming-washing recipes for KOA were developed.CONCLUSION: Chinese medicines for fuming-washing therapy of KOA mainly consist of wind-dampness-dispelling and cold-dispersing herbs, blood-activating and stasis-resolving herbs,and wind-dampness-dispelling and heat-clearing herbs. The treatment of fuming-washing therapy for KOA also includes dispelling wind-dampness and dispersing cold, activating blood and resolving stasis, and dispelling wind-dampness and clearing heat. Zhenzhutougucao(Herba Speranskiae Tuberculatae), Honghua(Flos Carthami), Niuxi(Radix Achyranthis Bidentatae), Shenjincao(Herba Lycopodii Japonici), Weilingxian(Radix et Rhizoma Clematidis Chinensis), Chuanwu(Radix Aconiti), Haitongpi(Cortex Erythrinae Variegatae), Ruxiang(Olibanum),Danggui(Radix Angelicae Sinensis), Caowu(Radix Aconiti Kusnezoffii), Moyao(Myrrha), and Aiye(Folium Artemisiae Argyi) are the main herbs used in the fuming-washing treatment for KOA. | Jun Liu Jianke Pan Yanping Wang Dingkun Lin Dan Shen Hongjun Yang Xiang Li Minghui Luo Xuewei Cao | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 32 |
| 2 | A novel quantified bitterness evaluation model for traditional Chinese herbs based on an animal ethology principle显示文摘Traditional Chinese herbs(TCH) are currently gaining attention in disease prevention and health care plans. However, their general bitter taste hinders their use. Despite the development of a variety of taste evaluation methods, it is still a major challenge to establish a quantitative detection technique that is objective, authentic and sensitive. Based on the two-bottle preference test(TBP), we proposed a novel quantitative strategy using a standardized animal test and a unified quantitative benchmark. To reduce the difference of results, the methodology of TBP was optimized. The relationship between the concentration of quinine and animal preference index(PI) was obtained. Then the PI of TCH was measured through TBP, and bitterness results were converted into a unified numerical system using the relationship of concentration and PI. To verify the authenticity and sensitivity of quantified results,human sensory testing and electronic tongue testing were applied. The quantified results showed a good discrimination ability. For example, the bitterness of Coptidis Rhizoma was equal to 0.0579 mg/mL quinine, and Nelumbinis Folium was equal to 0.0001 mg/mL. The validation results proved that the newassessment method for TCH was objective and reliable. In conclusion, this study provides an option for the quantification of bitterness and the evaluation of taste masking effects. | Xue Han Hong Jiang Li Han Xi Xiong Yanan He Chaomei Fu Runchun Xu Dingkun Zhang Junzhi Lin Ming Yang | 2018 | Acta Pharmaceutica Sinica B2018，8，2： | 17 |
| 3 | Ten-Hour Stable Noninvasive Brain-Computer Interface Realized by Semidry Hydrogel-Based Electrodes显示文摘Noninvasive brain computer interface(BCI)has been extensively studied from many aspects in the past decade.In order to broaden the practical applications of BCI technique,it is essential to develop electrodes for electroencephalogram(EEG)collection with advanced characteristics such as high conductivity,long term efectiveness,and biocompatibility.In this study,we devcloped a silver-nanowire/PVA hydrogc/mclamine sponge(AgPHMS)semidry EEG electrode for long lasting monitoring of EEG signal.Benefiting from the water storage capacity of PVA hydrogel,the clectrolyte solution can be continuously released to the scalpelctrode interface during used.The electrolyte solution can infiltrate the stratum corneum and reduce the scalp-electrode impedance to 10k0-15k0.The flexible structure enabls the electrode with mechanical stability,increases the wearing comfort,and reduces the scalp-electrode gap to reduce contact impedance.As a result,a long-term BCI application based on measurements of motion-onset visual evoked potentials(mVEPs)shows that the 3-hour BCI accuracy of the new electrode(77%to 100%)is approximately the same as that of conventional eletrodes supported by a conductive gel during the first hour.Furthermore,the BCI system based on the new electrode can retain low contact impedance for 10 hours on scalp,which greatly improved the ability of BCI technique. | Junchen Liu Sen Lin Wenzheng Li Yanzhen Zhao Dingkun Liu Zhaofeng He Dong Wang Ming Lei Bo Hong Hui Wu | 2022 | Research2022，，2： | 1 |
| 4 | Enhanced optical properties of A1- doped TiOz thin films in oxygen or nitrogen atmosphere显示文摘 | Lin Sushia Wu Dingkun | 2009 | Applied Surface Science2009，，255： | 1 |
| 5 | Phyllanthi Fructus:A modal medicinal and food homologous item in quality evaluation显示文摘Phyllanthi Fructus is a highly unique medicine and food homologous item,which exhibits distinctive flavor,notable nutritional value,and abundant pharmacological activity.It has enormous potential in the creation of health products and pharmaceuticals.However,due to the unique laws of quality formation and transfer of Phyllanthi Fructus,its appearance,shape,chemical compositions,nutrients,and sensory flavors are frequently greatly influenced by botanical resources,the processing and storage conditions.As a result,the current quality evaluation model is difficult to meet the needs of Phyllanthi Fructus as a medicine and food homologous item in the development of diversified products.This paper constructs the hierarchical utilization mode of Phyllanthi Fructus based on its unique quality formation and transmission laws,explores the quality evaluation model for food-oriented use and medicinal-oriented use,respectively,and systematically describes the quality evaluation idea under diversified application scenarios.This paper aims to serve as a reference for the construction of a quality evaluation model suitable for the medicine and food homologous item of Phyllanthi Fructus. | Gefei Li Yurou Jiang Dingkun Zhang Li Han Taigang Mo Sanhu Fan Haozhou Huang Junzhi Lin | 2023 | Chinese Herbal Medicines2023，15，3： | 0 |
| 6 | Recent Development of Gas-Solid Phase Chemiluminescence显示文摘Serving as a classic and interesting strategy,gas–solid phase chemiluminescence(CL)has recently been a rapidly growing area where CL is emitted through chemical reactions between gas and solid reactants occurred on the surface of solid matter.This CL system provided a sensitive and simple spectral method for investigating gas–solid phase reactions while information on the rate constants,intermediate productions,surface states and reaction mechanisms of interaction could be acquired.Recent progresses mainly concentrate on development of new gas–solid phase CL systems and their practical applications.This review paper summarized main classifications,mechanisms and applications of gas–solid phase CL.The future prospects for gas–solid phase CL are discussed. | Dingkun Zhang Jin‑Ming Lin | 2017 | Journal of Analysis and Testing2017，1，4： | 0 |
| 7 | Review of low-temperature plasma nitrogen fixation technology显示文摘Nitrogen fixation is essential for all forms of life,as nitrogen is required to biosynthesize fundamental building blocks of creatures,plants,and other life forms.As the main method of artificial nitrogen fixation,Haber–Bosch process(ammonia synthesis)has been supporting the agriculture and chemical industries since the 1910s.However,the disadvantages inherent to the Haber–Bosch process,such as high energy consumption and high emissions,cannot be ignored.Therefore,developing a green nitrogen fixation process has always been a research hotspot.Among the various technologies,plasma-assisted nitrogen fixation technology is very promising due to its small scale,mild reaction conditions,and flexible parameters.In the present work,the basic principles of plasma nitrogen fixation technology and its associated research progress are reviewed.The production efficiency of various plasmas is summarized and compared.Eventually,the prospect of nitrogen fixation using low-temperature plasma in the future was proposed. | Hang Chen Dingkun Yuan Angjian Wu Xiaoqing Lin Xiaodong Li | 2021 | Waste Disposal and Sustainable Energy2021，3，3： | 0 |
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