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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Physicochemical properties of native and partially gelatinized high-amylose jackfruit (Artocarpus heterophyllus Lain)seed starch显示文摘 | Tran P L Dang H D N Do V H | 2015 | Lebensmittel- Wissenschaft und-Technologie2015，62，2： | 1 |
| 3 | SAR image autofocus by sharpness optimization:a theoretical study显示文摘 | Morrison R L Do M N Munson D C | | 0，，09： | 1 |
| 4 | De-noising by soft-thresholding 显示文摘 | DO NOHO D L | 1995 | IEEE Transactions on Information Theory1995，41，3： | 1 |
| 5 | Resveratrol attenuates cisplatin-induced nephrotoxicity in rats显示文摘 | do AMARAL C L FRANCESCATO H D C COIMBRA T M | 2008 | Archives of Toxicology2008，82，6： | 1 |
| 6 | Direct conversion of triglycerides to olefins and paraffins over noble metal supported catalysts 显示文摘 | CHIAPPERO M DO P CROSSLEY S LOBBAN L L RESASCO D E | 2011 | Fuel2011，90，3： | 1 |
| 7 | Simultaneous tuning of power system damping controllers using genetic algorithms显示文摘 | DO BOMFIM A L B TARANTO G N FALCAO D M | 2000 | IEEE Trans on Power Systems2000，15，1： | 1 |
| 8 | Electronic structure of oxygen deficient BaTiO_3显示文摘 | Do D C Jaichan L | 2006 | Integrated Ferroelectrics2006，84，1： | 1 |
| 9 | Preliminary formu- lation development for aqueous surfactant-based soybean oil ex traction显示文摘 | Do L D Stevens T L Kibbey T C G | 2014 | Industrial Crops and Products2014，，62： | 1 |
| 10 | The nonsubsampled contourlet transform:theory,design,and applications显示文摘 | CUNHA D A L ZHOU J DO M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 11 | Isolation,identification andcomparison of the volatiles of peach fruit as related to harvest maturityand artificial ripening显示文摘 | DO J Y SALUNKHE D K OLSON L E | 1969 | Journal of Food Science1969，34，6： | 1 |
| 12 | Isolation,Identification and Comparison of the Volatiles of Peach Fruit as Related to Harvest Maturity and Artificial Ripening显示文摘 | DO J Y SALUNKHE D K OLSON L E | 1969 | Journal of Food Science1969，34，： | 1 |
| 13 | The nonsubsampled contourlet transform: theory, design, and applications 显示文摘 | Cunha L D Zhou J Do M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 14 | Recent advances in BNF with non-legume plants 显示文摘 | Baldani J I Caruso L Baldani V L D Goi S R Do bereiner J | 1997 | Soil Biol1997，29，： | 1 |
| 15 | Simultaneous tuning of power system damping controllers using genetic algorithms显示文摘 | Do Bomfim A L B Taranto G N Falcao D M | | 0，，01： | 1 |
| 16 | Simultaneous tuning of power system damping controllers using genetic algorithms 显示文摘 | do BOMFIM A L B TARANTO G N FALCAO D M | 2000 | IEEE Trans on Power Systems2000，15，1： | 1 |
| 17 | Com- parative toxicity of an acetogenin-based extract and commercial pesticides against citrus red mite显示文摘 | do Prado Ribeiro L Zanardi 0 Z Vendramim J D | 2014 | Exp Appl Aearol2014，64，1： | 1 |
| 18 | The nonsubsampled contourlet transform= theory, design, and applications 显示文摘 | Cunha A L D Zhou J P Do M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 19 | Accentuated osteoclastic response to parathy- roid hormone undermines bone mass acquisition in osteonectin-null mice 显示文摘 | Machado do Reis L Kessler CB Adams D J | 2008 | Bone2008，43，2： | 1 |
| 20 | Ideal spatial adaptation by wavelet shrinkage 显示文摘 | DO NOHO D L JOHNSTONE I M | 1994 | Biometrika1994，81，3： | 1 |
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