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| 1 | Progress Towards the 90-90-90 Targets for Controlling HIV --China, 2018显示文摘What is already known about this topic?Since the Joint United Nations Programme on HIV and AIDS(UNAIDS)announced the 90-90-90 targets to control the global HIV epidemic in 2014,many countries have undertaken innovative measures to achieve this goal.The National Center for AIDS/STD Control and Prevention(NCAIDS)of China CDC convenes experts annually to evaluate the national progress towards these indicators.The most recent progress of 90-90-90 targets in China has not been previously published.What is added by this report?At the end of 2018,the percentage of living with HIV(PLWH)who had received a confirmed HIV diagnosis in China was 68.9%(61.5%-78.3%).The antiretroviral treatment coverage of diagnosed PLWH was 83.4%,and among patients on treatment for at least 12 months,94.2%achieved viral suppression.This provides most recent progress of 90-90-90 target in China.What are the implications for public health practice?China has made significant strides in curbing the HIV epidemic,but analysis on progress for the first 90 target for HIV testing remains out of reach.Innovative testing strategies may need to be developed to ensure that more PLWH can be identified. | Yan Zhao Mengjie Han Ye Ma Dongmin Li | 2019 | China CDC weekly2019，1，1： | 7 |
| 2 | Prediction of geotemperatures in coal-bearing strata and implications for coal bed methane accumulation in the Bide-Santang basin,western Guizhou,China显示文摘The geothermal fields of coal-bearing strata have become a key topic in geological research into coal and coal bed methane(CBM).Based on temperature data from 135 boreholes that penetrate the Upper Permian coal-bearing strata in the Bide-Santang basin,western Guizhou,the precisions of geothermal predictions made using a geothermal gradient model and a gray sequence GM(1,1)model are analyzed and compared.The results indicate that the gray sequence GM(1,1)model is more appropriate for the prediction of geothermal fields.The GM(1,1)model is used to predict the geothermal field at three levels with depths of 500,1000,and 1500 m,as well as within the No.6,No.16,and No.27 coal seams.The results indicate that the geotemperatures of the 500 m depth level are between 21.0 and 30.0°C,indicating no heat damage;the geotemperatures of the 1000 m depth level are between 29.4 and 44.7°C,indicating the first level of heat damage;and the geotemperatures of the 1500 m depth level are between35.6 and 63.4°C,indicating the second level of heat damage.The CBM contents are positively correlated with the geotemperatures of the coal seams.The target area for CBM development is identified. | Chen Guo Yong Qin Dongmin Ma Zhaobiao Yang Lingling Lu | 2020 | International Journal of Mining Science and Technology2020，30，2： | 4 |
| 3 | An Experimental Study on the Conductivity Changes in Coal during Methane Adsorption-Desorption and their Influencing Factors显示文摘During the processes of methane adsorption and desorption,the internal structure of coal changes,accordingly leading to changes in electrical conductivity.In this paper,using low rank coal seams of the Yan'an Formation in the Dafbsi field as the research subject,the relationship between coal resistivity,methane adsorption quantity,and equilibrium pressure is analyzed through proximate analysis,mercury injection tests,low temperature liquid nitrogen adsorption tests,and coal resistivity measurements during methane adsorption and desorption.The results show that during the process of pressure rise and methane adsorption,the conductivity of coal increases,resulting from heat release from methane adsorption,coal matrix swelling and adsorbed water molecules replaced by methane,but the resistivity reduction gradually decreases.The relationship between coal resistivity and methane adsorption quantity and equilibrium pressure can be described by a quadratic function.During the processes of depressurization and desorption,the resistivity of coal rebounds slightly,due to decalescence of methane desorption,coal matrix shrinkage and water-gas displacement,and the relationship coincides with a linear function.Methane adsorption leads to irreversible changes in coal internal structure and enhances the coal conductivity,and resistivity can not be restored to the initial level even after methane desorption.The resistivity and reduction rate of durain are higher than those of vitrain,with relatively greater homogeneous pore throat structure and fewer charged particles in the double electric layer.In addition,moisture can enhance the conductivity of coal and makes it change more complexly during methane adsorption and desorption. | CHEN Yue MA Dongmin GUO Chen YANG Fu MU Tian GAO Zheng | 2019 | Acta Geologica Sinica(English Edition)2019，93，3： | 3 |
| 4 | Pore Structure and Permeability Characterization of Highrank Coal Reservoirs: A Case of the Bide-Santang Basin, Western Guizhou, South China显示文摘The methods of nuclear magnetic resonance(NMR)spectroscopy,mercury injection porosimetry(MIP),and gas-water relative permeability(GWRP)were used to reveal the pore structure and permeability characteristics of high-rank coal reservoirs in the Bide-Santang basin,western Guizhou,South China,to provide guidance for coalbed methane(CBM)exploration and exploitation and obtain direct insights for the development of CBM wells.The results indicate that the coal reservoirs in the study area are characterized by well-developed adsorption pores and poorly developed seepage pores.The bimodal NMR transverse relaxation time(T2)spectra and the mutation in the fractal characteristic of the MIP pore volume indicate poor connectivity between the adsorption pores and the seepage pores.As a result,the effective porosity is relatively low,with an average of 1.70%.The irreducible water saturation of the coal reservoir is relatively high,with an average of 66%,leading to a low gas relative permeability under irreducible water saturation.This is the main reason for the low recovery of high-rank CBM reservoirs,and effective enhanced CBM recovery technology urgently is needed.As a nondestructive and less time-consuming technique,the NMR is a promising method to quantitatively characterize the pores and fractures of coals. | GUO Chen QIN Yong MA Dongmin XIA Yucheng BAO Yuan CHEN Yue LU Lingling | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 3 |
| 5 | Single-cell RNA sequencing reveals B cell-T cell interactions in vascular adventitia of hyperhomocysteinemia-accelerated atherosclerosis显示文摘Dear Editor Cardiovascular disease(CVD)is the leading cause of death around the world(Truelsen,et al.,2015).Atherosclerosis,the dominant underlying cause of CVD,is a chronic inflam-matory disease characterized by lipid accumulation and immune cell infiltration in plaques and vessels(Weber,et al.,1950).The immune microenvironment is critical for the development of atherosclerosis.Homocysteine(Hcy)is an intermediate product of methionine metabolism,and its ele-vation in plasma(>15μmol/L),known as hyperhomocys-teinemia(HHcy),is an independent risk factor for atherosclerosis.HHcy is more common in Asia because of genetic factors and dietary habits(Huo,et al.,2015).folic acid supplement is one of the most important way to treat HHcy in clinic.Although HHcy potentiates atherosclerosis mainly through endothelial injury and inflammatory activa-tion(Luo,et al.,2016),a comprehensive understanding of the immune microenvironment and potential mechanisms in HHcy-accelerated atherosclerotic aortas(HHcy-AA)is still lacking. | Xiaolong Ma Jiacheng Deng Lulu Han Yuwei Song Yutong Miao Xing Du Guohui Dang Dongmin Yang Bitao Zhong Changtao Jiang Wei Kong Qingbo Xu Juan Feng Xian Wang | 2022 | Protein & Cell2022，13，7： | 2 |
| 6 | Microbial community structure analyses and cultivable denitrifier isolation of Myriophyllum aquaticum constructed wetland under low C/N ratio显示文摘With the rapid expansion of livestock production,the amount of livestock wastewater accumulated rapidly.Lack of biodegradable organic matter makes denitrification of livestock wastewater after anaerobic digestion more difficult.In this study,Myriophyllum aquaticum constructed wetlands(CWs)with efficient nitrogen removal performance were established under different carbon/nitrogen(C/N)ratios.Analysis of community composition reveals the change of M.aquaticum CWs in microbial community structure with C/N ratios.The proportion of Proteobacteria which is one of the dominant phyla among denitrifier communities increased significantly under low C/N ratio conditions.Besides,to obtain cultivable denitrifier that could be added into CWs in situ,33 strains belonging to phylum Proteobacteria were isolated from efficient M.aquaticum CWs,while the best-performing denitrification strain M3-1 was identified as Bacillus velezensis JT3-1(GenBank No.CP032506.1).Redundancy analysis and quadratic models showed that C/N ratio had significant effects on disposal of nitrate(NO_(3)^(−)-N)and the strains isolated could perform well in denitrification when C/N ratio is relatively low.In addition,they have relatively wide ranges of carbon sources,temperature and a high NO_(3)^(−)removal rate of 9.12 mg/(L·hr)at elevated concentrations of 800 mg/L nitrate.Thus,strains isolated from M.aquaticum CWs with low C/N ratio have a practical application value in the treatment of nitrate-containing wastewater.These denitrifying bacteria could be added to CWs to enhance nitrogen removal efficiency of CWs for livestock wastewater with low C/N ratio in the future. | Jialiang Zuo Lina Xu Jianlin Guo Shengjun Xu Shuanglong Ma Cancan Jiang Dongmin Yang Danhua Wang Xuliang Zhuang | 2023 | Journal of Environmental Sciences2023，，5： | 2 |
| 7 | B cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis显示文摘Hyperhomocysteinemia(HHcy)is a risk factor for chronic kidney diseases(CKDs)that affects about 85%CKD patients.HHcy stimulates B cells to secrete pathological antibodies,although it is unknown whether this pathway mediates kidney injury.In HHcytreated 2-kidney,1-clip(2K1C)hypertensive murine model,HHcy-activated B cells secreted anti-beta 2 glycoprotein I(β2GPI)antibodies that deposited in glomerular endothelial cells(GECs),exacerbating glomerulosclerosis and reducing renal function.Mechanistically,HHcy 2K1C mice increased phosphatidylethanolamine(PE)(18:0/20:4,18:0/22:6,16:0/20:4)in kidney tissue,as determined by lipidomics.GECs oxidative lipidomics validated the increase of oxidized phospholipids upon Hcy-activated B cells culture medium(Hcy-B CM)treatment,including PE(18:0/20:4+3[O],PE(18:0a/22:4+1[O],PE(18:0/22:4+2[O]and PE(18:0/22:4+3[O]).PE synthases ethanolamine kinase 2(etnk2)and ethanolamine-phosphate cytidylyltransferase 2(pcyt2)were increased in the kidney GECs of HHcy 2K1C mice and facilitated polyunsaturated PE synthesis to act as lipid peroxidation substrates.In HHcy 2K1C mice and Hcy-B CM-treated GECs,the oxidative environment induced by iron accumulation and the insufficient clearance of lipid peroxides caused by transferrin receptor(TFR)elevation and down-regulation of SLC7A11/glutathione peroxidase 4(GPX4)contributed to GECs ferroptosis of the kidneys.In vivo,pharmacological depletion of B cells or inhibition of ferroptosis mitigated the HHcy-aggravated hypertensive renal injury.Consequently,our findings uncovered a novel mechanism by which B cell-derived pathogenic anti-β2GPI IgG generated by HHcy exacerbated hypertensive kidney damage by inducing GECs ferroptosis.Targeting B cells or ferroptosis may be viable therapeutic strategies for ameliorating lipid peroxidative renal injury in HHcy patients with hypertensive nephropathy. | Xing Du Xiaolong Ma Ying Tan Fangyu Shao Chun Li Yang Zhao Yutong Miao Lulu Han Guohui Dang Yuwei Song Dongmin Yang Zhenling Deng Yue Wang Changtao Jiang Wei Kong Juan Feng Xian Wang | 2023 | Signal Transduction and Targeted Therapy2023，8，4： | 2 |
| 8 | A study of sequence stratigraphy of the Early Cretaceous coal-bearing series in the southeastern Songliao Basin, NE China显示文摘The Early Cretaceous is an important coal accumulation period in China.Abundant coal resources were formed in the southeastern margin of Songliao Basin.Sequence stratigraphy and coal accumulation of the Early Cretaceous in the southeastern margin of Songliao Basin have been studied on the basis of extensive outcrop and borehole data.Based on regional unconformity,basal erosional surfaces of incised valley fills,and abrupt depositional facies-reversal surface,six sequence boundaries have been identified,which subdivide the Early Cretaceous coal-bearing series into 5 third-order sequences.Sequence I corresponds to Huoshiling Formation,sequences II and III correspond to member I and member II of Shahezi Formation.Sequences IV and V correspond to member I and member II of Yingcheng Formation.Sequence I developed at the initial subsiding stage,sequence II and III developed during the stable subsiding stage,while sequence IV and V developed during the basin shrinkage stage.The major coal seams were developed in the sequence II and III,which ensured the relative balance between the increase rate of the accommodation space and the rate of peat accumulation for a longer period,thus forming a thick coal seam. | Kai Shao Longyi Shao Dongmin Ma Dongdong Wang Shuai Wang Di Gao | 2020 | International Journal of Coal Science & Technology2020，7，2： | 1 |
| 9 | Displacement desorption test of coalbed methane and its mechanism exploring显示文摘Through the test of CH4 displaced by CO2 using the coal sample as the adsorbent, this paper has found the coalbed methane (CBM) displacement desorption phenomenon under the natural conditions and CBM mining conditions. With the help of the adsorption theory of the modern physical chemistry and interfacial chemistry, the CBM competitive adsorption and displacement desorption mechanism are intensively discussed, and a new path for studying the CBM desorption mechanism in the CBM exploitation process is explored. | ZHANG Suian HUO Yongzhong YE Jianping TANG Shuheng MA Dongmin | 2005 | Chinese Science Bulletin2005，50，S1： | 1 |
| 10 | Synthesis and characterization of polyurethane/SiO2 nanoeomposites 显示文摘 | Gao Xiaoyan Zhu Yanchao Zhao Xu Wang Zichen An Dongmin Ma Yuejia | 2011 | Applied Surface Science2011，25，： | 1 |
| 11 | Implementing Routine HIV Screening in Hospitals:An Effective Practice to Expand HIV Testing—Xishuangbanna Prefecture,Yunnan Province,China,2019–2020显示文摘Summary What is already known about this topic?Research evidence is insufficient to suggest whether routine human immunodeficiency virus(HIV)screening in healthcare settings is effective in promoting greater awareness of HIV-positive status.What is added by this report?This study found that,following the implementation of routine HIV screening in hospitals in Xishuangbanna Prefecture,Yunnan Province,there was a significant increase in the number of HIV screenings,positive results,and the positive rate of HIV screening in primary-level hospitals.What are the implications for public health practice?Routine hospital-based HIV screening is effective in identifying HIV infections in areas with concentrated epidemics. | Yidan Wang Yanling Ma Qiyu Zhu Wenyue Xu Haolan Sun Dongmin Li Cong Jin | 2023 | China CDC weekly2023，5，13： | 0 |
| 12 | Adsorption and desorption behavior under coal–water–gas coupling conditions of high- and low-rank coal samples显示文摘High-and low-rank coalbed methane(CBM)are both important fields of CBM development in China,but their formation and production mechanisms differ considerably.The adsorption/desorption behavior of high-and low-rank coals under the coupling of coal–water–gas was investigated using two series of samples.Coal samples from Zhangjiamao(ZJM)coal mine,Ordos basin,and Sihe(SH)coal mine,Qinshui basin,were tested by isothermal adsorption–desorption experiment,natural imbibition experiment,nuclear magnetic resonance,mercury injection porosimetry,contact angle test,and permeability test.Isothermal adsorption and desorption experiments under dry,equilibrium water,and saturated water,were performed to explore the differences between the adsorption and desorption characteristics.The results show that the wettability and permeability of the ZJM low-rank coal sample was considerably higher than that of the SH high-rank coal sample.The imbibition process of the ZJM sample exhibited a high imbibition rate and high total-imbibition volume,whereas the SH sample exhibited a slow imbibition rate and low total-imbibition volume.The ZJM sample had a complex pore structure and diverse pore-size distribution with a lower mercury withdrawal efficiency at 59.60%,whereas the SH sample had a relatively uniform pore-size distribution with a higher mercury withdrawal efficiency at 97.62%.The response of adsorption and desorption of the ZJM sample to water was more significant than that of the SH sample.The desorption hysteresis of the ZJM sample was stronger than that of the SH sample and was more prominently affected by water,which was consistent with its strong wettability and complex pore-throat configuration.A comprehensive adsorption and desorption mode was constructed for high-and low-rank coal samples under coal–water–gas coupling condition.The research results are important to enrich the geological theory of high-and low-rank CBM and to guide efficient CBM recovery. | Chen GUO Jiang GOU Dongmin MA Yuan BAO Qingmin SHI Jiahao MENG Junzhe GAO Lingling LU | 2023 | Frontiers of Earth Science2023，17，1： | 0 |
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