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| 1 | 稳定化的零价Fe,FeS,Fe3O4纳米颗粒在土壤中的固砷作用机理显示文摘砷是一种广泛存在于土壤和地下水中的污染物.虽然多种铁基材料已被用于受污染土壤中砷的固定,但是关于稳定化的铁系纳米颗粒在该方面的研究鲜见报道.本文研究了3种经淀粉固定的铁系纳米颗粒(零价Fe,FeS,Fe3O4)对两种典型砷污染土壤(果园土壤、靶场土壤)的固砷作用.为了检测纳米颗粒对砷的去除效果,实验中采取了不同的Fe/As摩尔比(5:1~100:1)和接触时间(3或7d).土壤中砷的生物活性和浸出率分别用生理原理提取法(physiologically based extraction test,PBET)和毒性浸出程序(toxicity characteristic leaching procedure,TCLP)方法表征.在实验时间为3d、Fe/As摩尔比为100:1的实验中,果园砂质土壤中砷的生物活性从最初的71.3%±3.1%分别降至30.9%±3.2%(零价Fe)、37.6%±1.2%(FeS)和29.8%±3.1%(Fe3O4);靶场土壤中砷的浸出率从初始0.51%±0.11%分别降至0.24%±0.03%(零价Fe)、0.27%±0.04%(FeS)和0.17%±0.04%(Fe3O4).3种纳米颗粒中Fe3O4的固砷效率最高.比较两种土壤,可以看出该处理方法更适用于铁含量较低、砷初始浸出率较高的果园土壤.结果表明,对于砷污染的贫铁土壤、沉积物和固废等,环境友好的铁系纳米颗粒是十分有效的固砷材料. | 张美一 Wang Yu Zhao Dongye 潘纲 | 2009 | 科学通报2009，54，23： | 23 |
| 2 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 3 | Immobilization of arsenic in soils by stabilized nanoscale zero-valent iron, iron sulfide (FeS), and magnetite (Fe_3O_4) particles显示文摘Arsenic is a widespread contaminant in soils and groundwater. While various iron-based materials have been studied for immobilizing arsenic in contaminated soils, the feasibility of stabilized iron-based nanoparticles has not been reported. This study investigates the effectiveness of using three types of starch-stabilized iron-based nanoparticles, including zero-valent iron (ZVI), iron sulfide (FeS), and magnetite (Fe3O4), for immobilization of arsenic in two representative As-contaminated soils (an orchard soil and a fire range soil). To test the effect of the nanoparticles on the arsenic leachability, As-contaminated soils were amended with the nanoparticles at various Fe/As molar ratios (5:1―100:1) and contact time (3 and 7 d). After three days' treatments of a field-contaminated sandy soil, the PBET-based bioaccessibility of As decreased from an initial (71.3±3.1)% (mean±SD) to (30.9±3.2)% with ZVI, (37.6±1.2)% with FeS, and (29.8± 3.1)% with Fe3O4 at an Fe/As molar ratio of 100:1. The TCLP-based leachability of arsenic in a spiked fire range soil decreased from an initial (0.51±0.11)% to (0.24±0.03)%, (0.27±0.04)% and (0.17±0.04)% by ZVI, FeS, and Fe3O4 nanoparticles, respectively. The Fe3O4 nanoparticles appeared to be more effective (5% or more) than other nanoparticles for immobilizing arsenic. When the two soils were compared, the treatment is more effective on the orchard soil that has a lower iron content and higher initial leachability than on the range soil that already has a high iron content. These results suggest that these innocuous iron-based nanoparticles may serve as effective media for immobilization of As in iron-deficient soils, sediments or solid wastes. | ZHANG MeiYi WANG Yu ZHAO DongYe PAN Gang | 2010 | Chinese Science Bulletin2010，55，4： | 16 |
| 4 | Structural basis of AMPK regulation by adenine nucleotides and glycogen显示文摘激活安培的蛋白质 kinase (AMPK ) 为糖尿病,肥胖,和癌症的治疗是一个中央细胞的精力传感器和精力动态平衡,和一个有希望的药目标的管理者。这里我们人的 α 的现在的低分辨率的水晶结构; 1 β 2 γ 1 holo-AMPK 建筑群跳了到它的 allosteric 调节的人安培和肝糖模仿 cyclodextrin,两个在 phosphorylated (4.05 Å) 并且 non-phosphorylated (4.60 Å) 状态。另外,我们解决了 2.95 Å人的 kinase 领域(KD ) 的结构跳了到邻近的 autoinhibitory 领域(帮助) 并且表现了广泛生物化学并且 mutational 研究。一起,这些研究由安培和肝糖说明 allosteric AMPK 调整的内在的机制,其绑定改变在交替的帮助(安培) 和糖类绑定模块(肝糖) 之间的 equilibria 相互作用。 | Xiaodan Li Lili Wang X Edward Zhou Jiyuan Ke Parker W de Waal Xin Gu M H Eileen Tan Dongye Wang Donghai Wu H Eric Xu Karsten Melcher | 2015 | Cell Research2015，25，1： | 8 |
| 5 | CONTROL STRATEGY OF A PARALLEL HYBRID CAR WITH A METAL BELT-PLANETARY GEAR CONTINUOUSLY VARIABLE TRANSMISSION SYSTEM显示文摘The most remarkable characteristic of a metal belt-planetary gear continuously variable transmission is a wider ratio range and a bigger torque capacity than a conventional metal pushing belt continuously variable transmission. A parallel hybrid car with this transmission system not only can reduce fuel consumption and pollutant emission at a ECE city cycle, but also can keep the motor working in the most efficiency area and can be started by a lower power motor by oneself. At the same time, the continuously variable transmission system can realize the smooth switch between the motor and the engine. | Sun Dongye Qin Datong Wang HongyanState Key Laboratory of Mechanical Transmission, Chongqing University, Chongqing 400044, China | 2002 | Chinese Journal of Mechanical Engineering2002，15，3： | 5 |
| 6 | Novel mutation in OCRL leading to a severe form of Lowe syndrome显示文摘AIM: To investigate the phenotype and genotype of a family with X-linked recessive Lowe syndrome. METHODS: All the members in the Chinese pedigree underwent comprehensive ophthalmologic and systemic examinations. Genomic DNA was isolated from peripheral blood of the pedigree members and 100 unrelated healthy Chinese subjects. Direct sequencing was performed to screen the exons and intron boundaries of OCRL.RESULTS: The ophthalmological and systemic exami nations suggested that the affected individual had Lowe syndrome. The phenotype in the pedigree is severe and consistent among all the affected individuals except for an individual who additionally suffered from congenital heart disease and laryngeal cartilage dysplasia. Directio nal San ger sequenci ng identified a complex mutation c.(2368_2368delG;c.2370A>C) in the Rho-GTPase activating protein domain. This complex mutation causes termination of protein synthesis at amino acid 824 and result in a new peptide with 823 amino acids (p.Ala790ProfsX34). This mutation was not detected in 100 unrelated healthy Chinese subjects.CONCLUSION: Our findings expand the phenotypic and genotypic spectrum of Lowe syndrome. | Feng-Qi Zhou Qi-Wei Wang Zhen-Zhen Liu Xu-Lin Zhang Dong-Ni Wang Mei-Mei Dongye Hao-Tian Lin Wei-Rong Chen | 2019 | International Journal of Ophthalmology(English edition)2019，12，7： | 5 |
| 7 | Experimental study on electrical conductivity of dunite at high temperature and pressure——The evidence of electrical conductivity of cold mantle in the Gaize-Lugu area显示文摘The electrical conductivities of the dunite from the Qinghai-Xizang (Tibetan) Plateau were measured with the impedance spectra method at 1.0-4.0 GPa and 643-1093 K. The experimental results indicated that activation enthalpies of the dunite are smaller than 0.9 eV, the conduction mechanism in dunite may be attributed to the mixed electrical conduction involving grain interiors and boundaries. On the basis of the results of this experiment, we can deduce that there exists cold mantle in the area of Gaize-Lugu in the Qinghai-Xizang (Tibetan) Plateau by reverse methods from the magnetotelluric sounding data (conductivity-depths profile) available for western Tibet. The result provides the present cold mantle viewpoint with strong proof on the basis of high temperature and pressure experiments. | WANG Duojun LI Heping LIU Congqiang ZHAO Zhidan MO Xuanxue GUO Tieying SU Gengli DING Dongye | 2001 | Chinese Science Bulletin2001，46，24： | 5 |
| 8 | STUDY ON CONTROL STRATEGY OF CLUTCH STARTING FOR CAR WITH A METAL PUSHING BELT-PLANETARY GEAR CONTINUOUSLY VARIABLE TRANSMISSION SYSTEM显示文摘The automatic control of clutch startion in car with a metal pushing belt-planetary gear continuously variable transmission (CVT)is a complex problem.A suited control strategy is required to ralize quick and smooth start.A simulation state space equation is established on clutch startion control of a car startion process to weaken the jerk motion is introduced.The simulation results indicate that the jerk motion of clutch startiong is below 10m/s^3. | Sun Dongye Qin Datong Wang Hongyan State Key Laboratory of Mechanical Transmission, Chongqing University, Chongqing 400044,China | 2002 | Chinese Journal of Mechanical Engineering2002，15，1： | 5 |
| 9 | Effect of puerarin on myocardial perfusion and ventricular wall motion in patients with acute coronary syndrome显示文摘Objective To investigate the effects of puerarin (Pur) on myocardial perfusion and ventricular wall motion in patients with acute coronary syndrome (ACS).Methods Thirty-seven patients with ACS were randomly divided into two groups:conventional treatment group (n= 17,11 males,range of age:32-80 years,average age:60.9±4.9 years) and Pur treatment group (n=20,12 males,range of age:40-76 years,average age:62.7±3.5 years).Patients in the conventional treatment group received standard treatment according to the current guidelines,while patients in the Pur treatment group received intravenous administration of Pur (500 mg/day) for 10 days plus conventional treatment.Real-time myocardial contrast echocardiography (RT-MCE) was performed to evaluate the change in myocardial perfusion index (MPI) and ventricular wall motion index (VWMI) at admission and 10 days after treatment.Results At 10 days after treatment,MPI was significantly higher (P<0.01) and VWMI significantly lower (P<0.01) in the Pur group comparing with those in the conventional group.Conclusions Puerarin might improve myocardial microcirculation perfusion and ventricular wall motion in patients with ACS. | Ling Niu Dongye Li Yong Xia Defeng Pan Xiaoping Wang Yan Yan Li Liang Tongda Xu Cardiovascular Institute of Xuzhou Medical College, Department of Cardiology, Affiliated Hospital, Xuzhou Medical College, Xuzhou, Jiangsu 221002, China | 2008 | Journal of Geriatric Cardiology2008，5，3： | 3 |
| 10 | Impedance spectra of hot, dry gabbro at high temperature and pressure显示文摘Impedance spectra of hot, dry gabbro have been studied at 1.0~2.0 Gpa and 593~1173 K.The experimental results indicate that complex impedance depends on frequency of altering current. Impedance arcs representing grain interiors and grain boundaries conduction mechanism are displayed in the complex impedance plane. The impedance arc corresponding to grain interiors occurs over the range of 102~105 Hz, and the impedance arc corresponding to grain boundaries occurs over the range of 12~102 Hz. Each element of equivalent circuit corresponding to grain interiors is fit for complex nonlinear least square program. When garnet occurs in gabbro, the electrical conductivity of gabbro abruptly changes. | WANG Duojun, LIU Congqiang, LI Heping, YI Li, SU Genli and DING Dongye( Laboratory for Study of the Earth’s Interior and Geofluids, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China Institute of Geochemistry, Chinese Academy of Sciences, Guiyang 550002, China) | 2002 | Progress in Natural Science:Materials International2002，12，5： | 3 |
| 11 | Half mode substrate integrated waveguide,(HMSIW) bandpass filter显示文摘 | Wang Y Q HongW DongY D | | 0，，04： | 1 |
| 12 | Debris flow hazard mapping and land use planning显示文摘 | Dongye G L Wang L L Liu H Y | 2005 | Transactions of the CSAE2005，21，7： | 1 |
| 13 | Debris flow hazard mapping and land use planning显示文摘 | Dongye G L Wang L L Liu H Y etal | 2005 | Transactions of the CSAE2005，21，7： | 1 |
| 14 | Research on the dynamic characteristic of luffing tester for bucket wheel stackerreclaimer显示文摘 | WANG YUXING TANG YANQIN SUN DONGYE | 2001 | Chinese Society of Agricultural Machinery2001，37，11： | 1 |
| 15 | Debris flow hazard map- ping and land use planning 显示文摘 | DONGYE G L WANG L L LIU H Y | 2005 | Transactions of the CSCE2005，21，7： | 1 |
| 16 | Experimental behavior of stiffened concrete-filled thin-walled hollow steel structural (HSS) stub columns 显示文摘 | TAO Zhong HAN Linhai WANG Dongye | 2005 | Constructional Steel Research2005，61，7： | 1 |
| 17 | New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein显示文摘 | Xiujie Liu Xiaoli Huang Wanhua Lin Dongye Wang Yanyan Diao Honglin Li Xiaoyan Hui Yu Wang Aimin Xu Donghai Wu Ding Ke | 2011 | Bioorganic & Medicinal Chemistry Letters2011，，10： | 1 |
| 18 | CRUISE FUZZY CONTROL FOR AUTOMOBILE WITH CVT显示文摘To develop cruise control system of an automobile with the metal pushing V-belt type CVT,the dynamic model of automobile travelling longitudinally is established, and the fuzzy controller of control system is designed. Considering uncertainty system parameter and exterior resistance disturbances, the stability of controller is investigated by simulating. The results of its simulation show that the fuzzy controller designed has practicability. | Wang Hongyan,Qin Datong,Sun Dongye (State Key Laboratory of Mechanical Transmission, Chongqing University) | 2001 | Chinese Journal of Mechanical Engineering2001，14，3： | 1 |
| 19 | Experimental behaviour of concrete-filled stiffened thin-walled steel tubular columns显示文摘 | Tao Zhong Han Linhai Wang Dongye | 2007 | Thin-Walled Structures2007，45，5： | 1 |
| 20 | Inhibition of central sympathetic nervous tone improves cardiomyocyte contraction by increasing the response of beta 2-adrenergic receptor in aged rats显示文摘In the present study,selective β1-adrenergic receptor antagonist CGP20712A and selective β2-adrenergic receptor antagonist ICI 118551 were administered to isolated cardiomyocytes from young (4-6 months),aged (18-20 months),and clonidine-pretreated aged (18-20 months) Sprague-Dawley rats.Cardiomyocyte contraction amplitude was measured to assess cardiomyocyte response to the β-adrenergic receptor agonist,isoprenaline.CGP20712A reduced cardiomyocyte contraction amplitude in young and aged groups and significantly reduced contraction amplitude in cells from young rats.ICI 118551 had no effect on cardiomyocyte contraction amplitude in young rats,but significantly decreased contraction amplitude in the aged groups,in particular in the clonidine-pretreated aged rats.Results demonstrated that reduced central sympathetic tone improved cardiomyocyte contraction in aged rats by improving the response of β2-adrenergic receptor to isoprenaline. | Ying Wang Zhi Zhao Qin Wu Yanling Hao Chuanying Xu Yiwei Sun Hong Sun Changdong Yan Dongye Li | 2011 | Neural Regeneration Research2011，6，14： | 0 |
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