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7篇 您的检索式：作者名="Dorothee W"

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		题名	作者	年代	出处	被引量
	1	Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound显示文摘AIM:To evaluate whether contrast enhanced ultrasound(CEUS) might also be used for response prediction and early response evaluation in patients receiving bevacizumab based chemotherapy for metastasized colorectal cancer.METHODS:Thirty consecutive patients with non primary resectable liver metastases from colorectal cancer underwent CEUS before treatment(CEUS date 1) and before the second(CEUS date 2) and fourth(CEUS date 3) cycle of bevacizumab based chemotherapy.Three parameters [PEAK,Time to peak(TTP) and RISE RATE]were correlated with radiological response.RESULTS:For neoadjuvant purpose a reduction of tumour mass was required to assume clinical response.Based on these response criteria there was a significant(P < 0.001) correlation in TTP between metastases of responders(9.08 s) and non-responders(14.76 s) archived on CEUS date 1.By calculating a standardized quotient(metastases divided by normal liver tissue) we were able to define a cut off,predicting response with a sensitivity of 92.3 % and a specificity of 100 %.To reflect a palliative intention only those patients with progressive disease were classified as non-responders.In this stetting TTP was also significantly(P < 0.01) different between responders and non-responders.In contrast,Peak and Rise rate did not show any significant difference between responder and non-responder.CONCLUSION:CEUS might serve as a surrogate marker to predict treatment response in patients with metastasized colorectal cancer who receive antiangiogenic therapy.	Ramin Schirin-Sokhan Ron Winograd Christoph Roderburg Jhenee Bubenzer Nicole Cabral do ó Dorothee Guggenberger Hartmut Hecker Christian Trautwein Jens J W Tischendorf	2012	World Journal of Gastroenterology2012，18，6：	16
	2	Spatial discrimination learning of electrocutaneous stimuli isinfluenced by the type of stimulation 显示文摘	Katfin W Thomas W Dorothee S	2009	Brain Research2009，1281，：	1
	3	Arterio - venous differences of oxygen and transcranial Doppler sonography in the management of aneurysmatic subarachnoid hemor- rhage显示文摘	Matthias F Wlofram S Dorothee W	2008	J Clin Neuro2008，15，1：	1
	4	Scald burns in children aged 14 and younger in Australia and New Zealand—An analysis based on the Burn Registry of Australia and New Zealand (BRANZ)显示文摘	Ms Dorothee I Riedlinger Paul A Jennings Dale W Edgar John G Harvey Ms Heather J Cleland Fiona M Wood Peter A Cameron	2014	Burns2014，，：	1
	5	Protein kinase c translocation and src protein tyrosine activation mediate isofluraneinduced preconditioning:potential downstream taigets of mitochondrial adenosine triphosphate-sensitive potassiun channels and reactive oxygn species显示文摘	LYNDA M LUDWIG B S DOROTHEE W	2004	Anesthesiology2004，100，：	1
	6	Perfluorinated compounds - exposure assessment for the general population in western countries显示文摘	Frommea H Sheryl AT Wolfgang V Michael W Dorothee T	2009	International Journal of Hygiene and Environmental Health2009，212，：	1
	7	Microsurgery can cure most intracraniai dural arteriovenous fistulae of the sinus and non-sinus type显示文摘	Dorothee W Franz H Marios N P	2011	Neurosurgical Review2011，34，3：	1

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