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| 1 | A review on thermal conductivity of magnesium and its alloys显示文摘This review summarizes recent researching works the thermal conductivity of Mg–Zn,Mg–Al,Mg–Mn and Mg–RE alloys.Solute atoms,heat treatment,deformation and temperature,which have significant influence on the thermal conductivity of magnesium alloys,are highlighted.For an individual solute atom,its effects on thermal conductivity are highly dependent on its chemical valence,radius and extra-nuclear electrons.The thermal conductivity of Mg alloys is decreased by solution treatment,but improved by aging and/or annealing treatments.As for the deformed Mg alloys,the thermal conductivity along transverse or normal direction is superior to that of along extrusion or rolling direction.We expect this review is helpful for those who are working on developing Mg alloys with superior thermal conductivity.©2020 Published by Elsevier B.V.on behalf of Chongqing University. | Shubo Li Xinyu Yang Jiangtao Hou Wenbo Du | 2020 | Journal of Magnesium and Alloys2020，8，1： | 18 |
| 2 | Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2显示文摘Host cellular receptors play key roles in the determination of virus tropism and pathogenesis.However,little is known about SARS-CoV-2 host receptors with the exception of ACE2.Furthermore,ACE2 alone cannot explain the multi-organ tropism of SARS-CoV-2 nor the clinical differences between SARS-CoV-2 and SARS-CoV,suggesting the involvement of other receptor(s).Here,we performed genomic receptor profiling to screen 5054 human membrane proteins individually for interaction with the SARS-CoV-2 capsid spike(S)protein.Twelve proteins,including ACE2,ASGR1,and KREMEN1,were identified with diverse S-binding affinities and patterns.ASGR1 or KREMEN1 is sufficient for the entry of SARS-CoV-2 but not SARS-CoV in vitro and in vivo.SARS-CoV-2 utilizes distinct ACE2/ASGR1/KREMEN1(ASK)receptor combinations to enter different cell types,and the expression of ASK together displays a markedly stronger correlation with virus susceptibility than that of any individual receptor at both the cell and tissue levels.The cocktail of ASK-related neutralizing antibodies provides the most substantial blockage of SARS-CoV-2 infection in human lung organoids when compared to individual antibodies.Our study revealed an interacting host receptome of SARS-CoV-2,and identified ASGR1 and KREMEN1 as alternative functional receptors that play essential roles in ACE2-independent virus entry,providing insight into SARS-CoV-2 tropism and pathogenesis,as well as a community resource and potential therapeutic strategies for further COVID-19 investigations. | Yunqing Gu Jun Cao Xinyu Zhang Hai Gao Yuyan Wang Jia Wang Juan He Xiaoyi Jiang Jinlan Zhang Guanghui Shen Jie Yang Xichen Zheng Gaowei Hu Yuanfei Zhu Shujuan Du Yunkai Zhu Rong Zhang Jianqing Xu Fei Lan Di Qu Guoliang Xu Yun Zhao Dong Gao Youhua Xie Min Luo Zhigang Lu | 2022 | Cell Research2022，32，1： | 8 |
| 3 | Self-powered nanofiber-based screen-print triboelectric sensors for respiratory monitoring显示文摘科学、商业的进展将高要求放为便携电子学。然而,便携电子学的电源供应, breathability,和大量生产仍然有需要被克服的许多挑战。在这研究,一个自我动力的基于 nanofiber 的摩擦电传感器(SNTS ) 被批规模制造技术用 electrospinning 制作并且为经由呼吸监视监视的健康打印屏幕。典型地,一个拱门结构的 SNTS 被 nanofiber 膜和一个 Ag nanoparticle 电极装配。nanofibers 的堆积和 Ag nanoparticles 的传导性的网络越过整个设备保证一条煤气的隧道。当时, SNTS 的煤气的渗透象 6.16 mm/s 一样高,它有压到优势的优点与由密封演员组电影组成的通常使用的便携设备相比。由于 nanofiber 膜的柔软,不管它是否被弄弯,扭曲,或合拢, SNTS 显示出优秀电子输出性能。优异性质 SNTS 的皮友好,自我力量,和批制造例如 breathability,在保健监视和多功能的聪明的系统为他们的申请提供巨大的潜力。 | Ran Cao diaona Wang Shuyu Zhao Wei Yang Zuqing Yuan Yingying Yin Xinyu Du Nian-Wu Li Xiuling Zhang Xiuyan Li Zhong Lin Wang Congju Li | 2018 | Nano Research2018，11，7： | 8 |
| 4 | Medical expenditures for colorectal cancer diagnosis and treatment: A 10-year high-level-hospital-based multicenter retrospective survey in China, 2002-2011显示文摘Objective: Colorectal cancer(CRC) causes a substantial burden of disease in China and the evidence of economic burden triggered is fundamental for priority setting. The aim of this survey was to quantify medical expenditures and the time trends for CRC diagnosis and treatment in China.Methods: From 2012 to 2014, a hospital-based multicenter retrospective survey was conducted in 13 provinces across China. For each eligible CRC patient diagnosed from 2002 to 2011, clinical information and expenditure data were extracted using a uniform questionnaire. All expenditure data were reported in Chinese Yuan(CNY)using 2011 values.Results: Of the 14,536 CRC patients included, the average age at diagnosis was 58.2 years and 15.8% were stageI cases. The average medical expenditure per patient was estimated at 37,902 CNY [95 % confidence interval(95%CI): 37,282-38,522], and the annual average increase rate was 9.2% from 2002 to 2011(P for trend <0.001), with a cumulative increase of 2.4 times(from 23,275 CNY to 56,010 CNY). The expenditure per patient in stages Ⅰ, Ⅱ, Ⅲ and Ⅳ were 31,698 CNY, 37,067 CNY, 38,918 CNY and 42,614 CNY, respectively(P<0.001). Expenditure significantly differed within various subgroups. Expenses for drugs contributed the largest proportion(52.6%).Conclusions: These conservative estimates illustrated that medical expenditures for CRC diagnosis and treatment in tertiary hospitals in China were substantial and increased rapidly over the 10 years, with drugs continually being the main expense by 2011. Relatively, medical expenditures are lower for CRC in the earlier stages. These findings will facilitate the economic evaluation of CRC prevention and control in China. | Jufang Shi Guoxiang Liu Hong Wang Ayan Mao Chengcheng Liu Lanwei Guo Huiyao Huang Jiansong Ren Xianzhen Liao Yana Bai Xiaojie Sun Xinyu Zhu Jialin Wang Bingbing Song Jinyi Zhou Lin Zhu Haike Lei Yuqin Liu Yunyong Liu Lingbin Du Yutong He Kai Zhang Ni Li Wanqing Chen Min Dai Jie He | 2019 | Chinese Journal of Cancer Research2019，31，5： | 8 |
| 5 | Research progress of in-situ gelling ophthalmic drug delivery system显示文摘Blindness and vision impairment are the most devastating global health problems resulting in a substantial economic and social burden.Delivery of drug to particular parts of the anterior or posterior segment has been a major challenge due to various protective barriers and elimination mechanisms associated with the unique anatomical and physiological nature of the ocular system.Drug administration to the eye by conventional delivery systems results in poor ocular bioavailability(<5%).The designing of a novel approach for a safe,simple,and effective ocular drug delivery is a major concern and requires innovative strategies to combat the problem.Over the past decades,several novel approaches involving different strategies have been developed to improve the ocular delivery system.Among these,the ophthalmic in-situ gel has attained a great attention over the past few years.This review discussed and summarized the recent and the promising research progress of in-situ gelling in ocular drug delivery system. | Yumei Wu Yuanyuan Liu Xinyue Li Dereje Kebebe Bing Zhang Jing Ren Jun Lu Jiawei Li Shouying Du Zhidong Liu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，1： | 7 |
| 6 | PRODUCTS RANKING THROUGH ASPECT-BASED SENTIMENT ANALYSIS OF ONLINE HETEROGENEOUS REVIEWS显示文摘 | Chonghui Guo Zhonglian Du Xinyue Kou | 2018 | Journal of Systems Science and Systems Engineering2018，27，5： | 5 |
| 7 | In vitro and in silico analysis of dual-function peptides derived from casein hydrolysate显示文摘There is no study on food-derived peptide with both anticoagulant and angiotensin I-converting enzyme inhibitory (ACEI) activities yet. In this work, the anticoagulant and ACEI activities of the casein hydrolysates released by pepsin digestion were evaluated for the first time to the best of our knowledge. Results indicated that the casein hydrolysate exhibited potent anticoagulant activity by prolonging the thrombin time (TT) and the activated partial thromboplastin time (APTT). Compared with control samples, at 10 mg/mL, the TT and APTT of casein hydrolysate were 186.0 % ± 6.6 % and 163.5 % ± 7.4 %, respectively. The casein hydrolysate also showed a strong ACEI activity with an IC50 value of 1.775 mg/mL. The components of the bioactive casein hydrolysate were analyzed by nanoscale liquid chromatography quadrupole time-of-flight tandem mass spectrometry (NanoLC-Q-TOF-MS/MS). Total of 115 peptides were identified, among which 34, 9, 55 and 17 peptides were derived from α_(s1-), α_(s2-), β-, and κ-casein, respectively. The results of PeptideRanker and PepSite 2 analysis showed that 6 peptides (FRQFYQL, NENLLRF, NPWDQVKR, PVVVPPFLQ, PVRGPFPIIV, and ARHPHPHLSF) have both ACEI and anticoagulant activities by binding to the active sites of ACE and thrombin. This study indicated that casein is a potential functional food supplement that can be used for medical purposes. | Maolin Tu Xinyu Qiao Cong Wang Hanxiong Liu Shuzhen Cheng Zhe Xu Ming Du | 2021 | Food Science and Human Wellness2021，10，1： | 4 |
| 8 | Natural polymer-derived photocurable bioadhesive hydrogels for sutureless keratoplasty显示文摘Keratoplasty is the gold standard treatment for visual impairment caused by corneal damage.The use of suturing as the bonding method is the source of many complications following keratoplasty.Currently available corneal adhesives do not have both adequate adhesive strength and acceptable biocompatibility.Herein,we developed a photocurable bioadhesive hydrogel which was composed of gelatin methacryloyl and oxidized dextran for sutureless keratoplasty.The bioadhesive hydrogel exhibited high light transmittance,resistance to enzymatic degradation and excellent biocompatibility.It also had higher adhesive strength than commercial adhesives(fibrin glue).In a rabbit model of lamellar keratoplasty,donor corneal grafts could be closely bonded to the recipient corneal bed and remained attached for 56 days by using of this in situ photopolymerized bioadhesive hydrogel.The operated cornea maintained transparent and noninflamed.Sutureless keratoplasty using bioadhesive hydrogel allowed rapid graft re-epithelialization,typically within 7 days.In vivo confocal microscopic and histological evaluation of the operated cornea did not show any apparent abnormalities in terms of corneal cells and ultrastructure.Thus,this bioadhesive hydrogel is exhibited to be an appealing alternative to sutures for keratoplasty and other corneal surgeries. | Xuan Zhao Saiqun Li Xinyue Du Weihua Li Qian Wang Dalian He Jin Yuan | 2022 | Bioactive Materials2022，7，2： | 4 |
| 9 | Tunable oxygen vacancy concentration in vanadium oxide as mass-produced cathode for aqueous zinc-ion batteries显示文摘Oxygen vacancy(Vö)is important in the modification of electrode for rechargeable batteries.However,due to the scarcity of suitable preparation strategy with controllable Vöincorporation,the impact of Vöconcentration on the electrochemical performances remains unclear.Thus,in this work,Vö-V_(2)O_(5)-PEDOT(VöVP)with tunable Vöconcentration is achieved via a spontaneous polymerization strategy,with the capability of mass-production.The introduction of poly(2,3-dihydrothieno-1,4-dioxin)(PEDOT)not only leads to the formation of Vöin V_(2)O_(5),but it also results in a larger interlayer spacing.The as-prepared Vö-V_(2)O_(5)-PEDOT-20.3%with Vöconcentration of 20.3%(denoted as VöVP-20)is able to exhibit high capacity of 449 mAh·g^(−1) at current density of 0.2 A·g^(−1),with excellent cyclic performance of 94.3% after 6,000 cycles.It is shown in the theoretical calculations that excessive Vöin V_(2)O_(5) will lead to an increase in the band gap,which inhibits the electrochemical kinetics and charge conductivity.This is further demonstrated in the experimental results as the electrochemical performance starts to decline when Vöconcentration increases beyond 20.3%.Thus,based on this work,scalable fabrication of high-performance electrode with tunable Vöconcentration can be achieved with the proposed strategy. | Yehong Du Xinyu Wang Juncai Sun | 2021 | Nano Research2021，14，3： | 4 |
| 10 | Ultrathin lanthanide oxides nanomaterials: synthesis, properties and applications显示文摘Over the past decade, ultrathin lanthanide oxides(Ln_2O_3, Ln = La to Lu) nanomaterials have been intensively studied in the fields of rare earth materials science. This unique class of nanomaterials has shown many unprecedented properties(big surface area, high surface effect, physical and chemical activities) and is thus being explored for numerous promising applications. In this review, a brief introduction of ultrathin Ln_2O_3 nanomaterials was given and their unique advantages were highlighted. Then, the typical synthetic methodologies were summarized and compared(thermal decomposition, solvothermal, soft template, co-precipition and microwave etc.). Due to the high surface effect, some promising applications of ultrathin Ln_2O_3 nanomaterials, such as drug delivery and catalysis of CO oxidation, were reviewed. Finally, on the basis of current achievements on ultrathin Ln_2O_3 nanomaterials, personal perspectives and challenges on future research directions were proposed. | Xinyu Zhang Yongwei Wang Fenghua Cheng Zhiping Zheng Yaping Du | 2016 | Science Bulletin2016，61，18： | 3 |
| 11 | INTERFERENCE BY NON-HOST PLANT ROOTS AND ROOT EXUDATES IN THE INFECTION PROCESSES OF PHYTOPHTHORA NICOTIANAE显示文摘Crop rotations are widely used because they can significantly reduce the incidence of pests and diseases.The interactions between non-host roots and pathogens may be key in the inhibition of soilborne pathogens in crop rotations.Interactions between fennel(Foeniculum vulgare)roots/root exudates and Phytophthora nicotianae were investigated because of the known allelopathy between fennel and tobacco(Nicotiana tabacum).The effects of the key compounds in the fennel rhizosphere on the mycelial growth and zoospore behavior of P.nicotianae were assessed.The roots of fennel attracted P.nicotianae zoospores and inhibited their motility and the germination of cystospores,with some cystospores rupturing.4-ethylacetophenone,vanillin and N-formylpiperidine were consistently identified in the fennel rhizosphere and were found to interfere with the infection of P.nicotianae,especially vanillin.Hyphae treated with these compounds produced more abnormal branches and accumulated reactive oxygen species.These interspecific interactions between non-host roots and pathogens were found to be an important factor in the inhibition by fennel of infection by P.nicotianae. | Yuxin YANG He ZHANG Yuting FANG Ying LI Xinyue MEI Huichuan HUANG Fei DU Shusheng ZHU Min YANG Yixiang LIU | 2021 | Frontiers of Agricultural Science and Engineering2021，8，3： | 3 |
| 12 | A deep learning-integrated phenotyping pipeline for vascular bundle phenotypes and its application in evaluating sap flow in the maize stem显示文摘Plant vascular bundles are responsible for water and material transportation, and their quantitative and functional evaluation is desirable in plant research. At the single-plant level, the number, size, and distribution of vascular bundles vary widely, posing a challenge to automatically and accurately identifying and quantifying them. In this study, a deep learning-integrated phenotyping pipeline was developed to robustly and accurately detect vascular bundles in Computed Tomography(CT) images of stem internodes. Two semantic indicators were used to evaluate and identify a suitable feature extraction network for semantic segmentation models. The epidermis thickness of maize stem was evaluated for the first time and adjacent vascular bundles were improved using an adaptive watershed-based approach. The counting accuracy(R^(2)) of vascular bundles was 0.997 for all types of stem internodes, and the measured accuracy of size traits was over 0.98. Combining sap flow experiments, multiscale traits of vascular bundles were evaluated at the single-plant level, which provided an insight into the water use efficiency of the maize plant. | Jianjun Du Ying Zhang Xianju Lu Minggang Zhang Jinglu Wang Shengjin Liao Xinyu Guo Chunjiang Zhao | 2022 | The Crop Journal2022，10，5： | 3 |
| 13 | Effect of co-existing organic compounds on adsorption of perfluorinated compounds onto carbon nanotubes显示文摘共存的有机化合物可以在水的环境影响 perfluorinated 混合物(陆军) 和碳 nanotubes 的吸附。 perfluorooctane sulfonate ( PFOS )的吸附, perfluorooctane 酸( PFOA ), perfluorobutane sulfonate ( PFBS ),和 perfluorohexane sulfonate ( PFH x S )在太古的多围的碳 nanotubes ( MWCNTs-Pri )上, carboxyl functionalized MWCNT ( MWCTNs-COOH ),并且氢氧根 functionalized MWCNT ( MWCNT --哦)面对腐殖的酸,1萘粉,酚,和安息香的酸被学习。PFOS 的吸附动力学被 pseudo-second-order 模型描述很好,吸着平衡几乎在 24 h 以内被到达。PFOS 吸附上的共存的有机化合物的效果跟随了腐殖的酸的减少的顺序 >1 萘粉 > 安息香的酸 > 酚。PFOS 的吸附的数量面对共存显著地减少了或预装腐殖的酸,和两个吸附精力,导致 PFOS 的减少并且三 MWCNT 上的有效吸附地点减少了吸附。与增加 pH,由三 MWCNT 的 PFOS 移动面对腐殖的酸和酚减少了。MWCNT 上的不同陆军的吸附的数量在 PFBS x S < PFOA < PFOS。起始的集中的增加和共存的有机化合物的芳香的戒指的数字在 MWCNT 上压制了 PFOS 吸附。 | Shubo DENG Yue BEI Xinyu LU Ziwen DU Bin WANG Yujue WANG Jun HUANG Gang YU | 2015 | Frontiers of Environmental Science & Engineering2015，9，5： | 3 |
| 14 | Cellulose Nanopaper:Fabrication,Functionalization,and Applications显示文摘Cellulose nanopaper has shown great potential in diverse fields including optoelectronic devices,food packaging,biomedical application,and so forth,owing to their various advantages such as good flexibility,tunable light transmittance,high thermal stability,low thermal expansion coefficient,and superior mechanical properties.Herein,recent progress on the fabrication and applications of cellulose nanopaper is summarized and discussed based on the analyses of the latest studies.We begin with a brief introduction of the three types of nanocellulose:cellulose nanocrystals,cellulose nanofibrils and bacterial cellulose,recapitulating their differences in preparation and properties.Then,the main preparation methods of cellulose nanopaper including filtration method and casting method as well as the newly developed technology are systematically elaborated and compared.Furthermore,the advanced applications of cellulose nanopaper including energy storage,electronic devices,water treatment,and high-performance packaging materials were highlighted.Finally,the prospects and ongoing challenges of cellulose nanopaper were summarized. | Wei Liu Kun Liu Haishun Du Ting Zheng Ning Zhang Ting Xu Bo Pang Xinyu Zhang Chuanling Si Kai Zhang | 2022 | Nano-Micro Letters2022，14，6： | 2 |
| 15 | Ultra-robust triboelectric nanogenerator for harvesting rotary mechanical energy显示文摘 | Xinyu Du Nianwu Li Yuebo Liu Jiaona Wang Zuqing Yuan Yingying Yin Ran Cao Shuyu Zhao Bin Wang Zhong Lin Wang Congju Li | 2018 | Nano Research2018，11，5： | 2 |
| 16 | Ligand assisted copper-catalyzed Ullmann cross coupling reaction of bromaminic acid with amines显示文摘Three types of ligands have been developed for copper-catalyzed Ullmann cross coupling reaction of bromaminic acid with amines in aqueous solution. Ligands with large steric hindrance and strong electron-donating capacity were beneficial to the reaction. UV–Vis and CV analyses demonstrated that these ligands had strong coordination with copper(I), implying the effect of ligand coordination ability on the stability and catalytic activity of catalytic system. | Beibei Shao Hongying Du Xinyu Hao Rongwen Lu Yi Luo Shufen Zhang | 2016 | Chinese Journal of Chemical Engineering2016，24，8： | 2 |
| 17 | Dynamic analysis of a concentrating photovoltaic/concentrating solar power (CPV/CSP) hybrid system显示文摘Concentrating photovoltaic/concentrating solar power(CPV/CSP)systems suffer from varying irradiation and extreme working conditions.In this study,a dynamic physical model is developed for the CPV/CSP hybrid system to analyze the dynamic responses of several key parameters,such as the solar radiation saltation or linear variation to represent the typical weather variations.The results show that the hybrid system could rapidly reach the steady state in less than about 53 s after the solar radiation saltation increases or decreases by 10%.The response time reflects that the thermal hysteresis of the hybrid system is mainly determined by varying the outlet temperature of R134a from the solar thermal receiver.Meanwhile,when the solar radiation changes linearly,a lower gradient is beneficial to remit the thermal hysteresis of the hybrid system and improve the thermal stability,and the parameters could be treated as the steady state values with a gradient of less than 0.2 W m^-2 s^-1.Afterward,the quasi-steady state model was used to analyze the all-day dynamic performance of the hybrid system.It shows that the power output and the flow rate are directly related to the direct normal irradiance(DNI),while the outlet temperature of R134a vapor could be almost constant except for the starting and stopping periods. | HAN Xue XU Chao PAN XinYu JU Xing DU XiaoZe | 2019 | Science China(Technological Sciences)2019，62，11： | 2 |
| 18 | Heavy Metal Remediation in Sludge Compost: Recent Progress显示文摘The safe and efficient disposal and utilization of sludge are major issues to be solved in solid waste treatment and environmental protection due to the complex characteristics of sludge and the low rate of innocuous treatments.Composting is a process of decomposing organic matter and transformed low-molecular organic acids into high-molecular humus substances under the action of microorganisms.Although land-use after composting has become an important direction for sludge treatment,heavy metal pollution is still the bottleneck problem restrict-ing land use of sludge compost.Adding zeolite,hydroxyapatite,and other conditioning agents to the composting process affects the concentration or form of some heavy metals and effectively reduces the environmental risk.Lime and phosphorus modifiers change heavy metal speciation in samples,playing a role in decreasing biological availability and mobility.In this study,the effects of sludge composting treatment and conditioning agents on the concentrations and forms of heavy metals are reviewed.This review will provide a theoretical basis to treat heavy metals in sludge composting and lay the foundation for the land utilization and waste recycling of sludge. | Rongwei Xiong Xiufang Gao Xinyue Tu Yilin Mao Li Jiang Lu Zheng Yitong Du | 2022 | Journal of Renewable Materials2022，10，2： | 2 |
| 19 | Compatibilization of PPO/LCP blends by semi-interpenetrating liquid crystalline polymer networks LCP/PS显示文摘 | Xinyu Du Deshan Liu | 2001 | Macromol Mater Eng2001，274，1： | 1 |
| 20 | Curcumin promotes apoptosis in human lung adenocarcinoma cells throughmiR-186* signaling pathway显示文摘 | Jian Zhang Yongping Du Changgui Wu Xinling Ren Xinyu Ti Jieran Shi Feng Zhao Hong Yin | 2010 | Oncology Reports2010，，5： | 1 |
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