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| 1 | Rapid screening for citrus canker resistance employing pathogen-associated molecular pattern-triggered immunity responses显示文摘Citrus canker,caused by the bacterial pathogen Xanthomonas citri ssp.citri(Xcc),has been attributed to millions of dollars in loss or damage to commercial citrus crops in subtropical production areas of the world.Since identification of resistant plants is one of the most effective methods of disease management,the ability to screen for resistant seedlings plays a key role in the production of a long-term solution to canker.Here,an inverse correlation between reactive oxygen species(ROS)production by the plant and the ability of Xcc to grow and form lesions on infected plants is reported.Based on this information,a novel screening method that can rapidly identify citrus seedlings that are less susceptible to early infection by Xcc was devised by measuring ROS accumulation triggered by a 22-amino acid sequence of the conserved N-terminal part of flagellin(flg22)from X.citri ssp.citri(Xcc-flg22).In addition to limiting disease symptoms,ROS production was also correlated with the expression of basal defense-related genes such as the pattern recognition receptors LRR8 and FLS2,the leucine-rich repeat receptor-like protein RLP12,and the defense-related gene PR1,indicating an important role for pathogen-associated molecular pattern-triggered immunity(PTI)in determining resistance to citrus canker.Moreover,the differential expression patterns observed amongst the citrus seedlings demonstrated the existence of genetic variations in the PTI response among citrus species/varieties. | Marco Pitino Cheryl M Armstrong Yongping Duan | 2015 | Horticulture Research2015，2，1： | 11 |
| 2 | 典型相关分析在中国青少年健康行为影响因素探讨中的应用显示文摘目的运用典型相关方法从多维度探讨几组中国青少年健康行为之间的相互关系。方法数据来自2003年全球学校学生健康状况调查——中国区(GSHS)。健康行为变量分为四组:健康行为、心理、其他个人行为和环境行为组。典型相关分析以SPSS13.0完成。结果不良心理状态主要由高水平的孤独、焦虑、有自杀想法、有自杀计划和抑郁来反映,健康行为主要由少吸烟、少饮酒、较少静坐行为和经常吃早餐来反映,其他不健康个人行为包括较少安全带使用、参与斗殴和旷课,而不良环境行为由较多被欺负、受到严重伤害和他人在面前吸烟决定。处于不良心理状态个体发生不健康行为的可能性越大,而暴露于不良环境行为越多者,其心理风险也越大。结论行为是一种多元变量,没有一个或一组心理或其他行为变量能够单独影响和解释中国青少年的健康行为。在进行这类因素的关联分析时,可更多地考虑应用典型相关分析方法。 | Teresa M. Merrick 张莹 Ian M Newman Duane Shell 钱玲 | 2008 | 中国卫生统计2008，25，2： | 6 |
| 3 | Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation显示文摘航线发炎是许多呼吸障碍的特点,例如气喘和膀胱的纤维变性。在发炎触发的航线基因表示的变化在这些疾病的致病起一个关键作用。基因连接研究建议 ESE-2 和 ESE-3,编码上皮特定的 Ets-domain-containing 抄写因素,是候选人气喘危险性基因。我们这里报导 et 家庭抄写因素 ESE-1 的另一个成员的表示,以及 ESE-3,起来在支气管的上皮的房间线由煽动性的 cytokines interleukin-1beta (IL-1beta ) 和肿瘤坏死 factor-alpha (TNF-alpha ) 调整了。有 IL-1beta 和 TNF-alpha 的这些房间的处理为 ESE-1 和 ESE-3 导致了信使 rna 表示的戏剧的增加。我们证明导致的表示被抄写因素 NF-kappaB 的激活调停。我们描绘了 ESE-1 和 ESE-3 倡导者并且识别了为导致 cytokine 的表达式被要求的 NF-kappaB 有约束力的序列。另外,我们也表明那 ESE-1 在上面调整 ESE-3 表示, down 由 cytokines 调整它的自己的正式就职。最后,我们在 Elf3 显示出那(对人的 ESE-1 相应) 猛烈老鼠,煽动性的 cytokine interleukin-6 (IL-6 ) 的表示是调整的 down。我们的调查结果建议 ESE-1 和 ESE-3 在航线发炎起一个重要作用。 | Jing Wu Rongqi Duan Huibi Cao Deborah Field Catherine M Newnham David R Koehler Noe Zamel Melanie A Pritchard Paul Hertzog Martin Post A Keith Tanswell Jim Hu | 2008 | Cell Research2008，18，6： | 6 |
| 4 | Heterogeneity of aberrant immunoglobulin expression in cancer cells显示文摘Accumulating evidence has shown that immunoglobulin(Ig)is‘unexpectedly’expressed by epithelial cancer cells and that it can promote tumor growth.The main purpose of this study was to explore the components of the cancerous Ig and its possible function.The presence of cancerous Ig in the Golgi apparatus was confirmed by immunofluorescence,indirectly suggesting that the cancerous Ig was processed and packaged in cancer cells.Western blot analysis and ELISA results indicated that cancer cells produced membrane Ig and secreted Ig into the supernatant fraction.The cancerous Ig consists of an a heavy chain and a k light chain.Finally,by analyzing the Ig components pulled down by protein A beads,the cancerous Ig was found to be structurally distinct from normal Ig.The cancerous Ig was truncated or aberrant.Although the underlying mechanism that causes the abnormalities has not been determined,our current discoveries strengthen our previous findings and promise fruitful future explorations. | Duosha Hu Zhi Duan Ming Li Yiqun Jiang Haidan Liu Hui Zheng Lili Li Ann M Bode Zigang Dong Ya Cao | 2011 | Cellular & Molecular Immunology2011，8，6： | 5 |
| 5 | Molecular mechanisms behind the accumulation of ATP and H_(2)O_(2) in citrus plants in response to‘Candidatus Liberibacter asiaticus’infection显示文摘Candidatus Liberibacter asiaticus(Las)is a fastidious,phloem-restricted pathogen with a significantly reduced genome,and attacks all citrus species with no immune cultivars documented to date.Like other plant bacterial pathogens,Las deploys effector proteins into the organelles of plant cells,such as mitochondria and chloroplasts to manipulate host immunity and physiology.These organelles are responsible for the synthesis of adenosine triphosphate(ATP)and have a critical role in plant immune signaling during hydrogen peroxide(H2O2)production.In this study,we investigated H2O2 and ATP accumulation in relation to citrus huanglongbing(HLB)in addition to revealing the expression profiles of genes critical for the production and detoxification of H2O2 and ATP synthesis.We also found that as ATP and H2O2 concentrations increased in the leaf,so did the severity of the HLB symptoms,a trend that remained consistent among the four different citrus varieties tested.Furthermore,the upregulation of ATP synthase,a key enzyme for energy conversion,may contribute to the accumulation of ATP in infected tissues,whereas downregulation of the H2O2 detoxification system may cause oxidative damage to plant macromolecules and cell structures.This may explain the cause of some of the HLB symptoms such as chlorosis or leaf discoloration.The findings in this study highlight important molecular and physiological mechanisms involved in the host plants’response to Las infection and provide new targets for interrupting the disease cycle. | Marco Pitino Cheryl M Armstrong Yongping Duan | 2017 | Horticulture Research2017，4，1： | 3 |
| 6 | Epicardium-to-fat transition in injured heart显示文摘 | Qiaozhen Liu Xiuzhen Huang Jin-Hee Oh Ruei-Zeng Lin Shengzhong Duan Ying Yu Rui Yang Ju Qiu Juan M Melero-Martin William T Pu Bin Zhou | 2014 | Cell Research2014，24，11： | 2 |
| 7 | Isoprene and its degradation products as strong ozone precursors in Insubria, Northern Italy显示文摘 | M Duane B Poma D Rembges C Astorga B.R Larsen | 2002 | Atmospheric Environment2002，，24： | 2 |
| 8 | 文化定位与高中生饮酒行为之间的关系显示文摘目的旨在探讨文化和饮酒之间的关系。方法于2002年1月对北京市5所高中的1091名高一至高三学生用文化定位量表和饮酒行为量表进行了匿名问卷调查。结果三类不同饮酒行为组的文化定位均值之间差异有显著性(F=30.64,P=0.03)。两两比较的结果表明这种差异表现在非饮酒组[(2.98±0.28)分]和偶尔饮酒组[(3.08±0.27)分]、非饮酒组和经常饮酒组[(3.13±0.26)分]之间。结论本调查结果表明,越“西方”化的学生越可能成为饮酒者,越“传统”化的学生成为饮酒者的可能性越低,同时它也表明西方文化可能对我国青少年的饮酒行为有影响。 | 薛建平 Ian M Newman Duane F Shell 方晓义 | 2005 | 中国行为医学科学2005，14，11： | 2 |
| 9 | Emergence of the GII4/2006b variant and recombinant noroviruses in China显示文摘 | Jin M Xie HP Duan ZJ | 2008 | J Med Viro12008，80，11： | 1 |
| 10 | Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats 显示文摘 | Zhao L R Duan W M Reyes M | 2002 | Exp Neurol2002，174，1： | 1 |
| 11 | ATP-induced changes in energy status and membrane integrity of harvested litchi fruit and its relation to pathogen resistance 显示文摘 | YI C QU H X JIANG Y M SHI J DUAN X W JOYCE D C LI Y B | 2008 | Journal of Phytopathology2008，156，： | 1 |
| 12 | Structural,gene expression,and functional analysis of the fugu(Takifugu rubripes) insulin-like growth factor binding protein-4 gene显示文摘 | Li M Li Y Duan C | 2009 | J Endocrin2009，296，3： | 1 |
| 13 | The Impact of Auditor Tenure on Initial Bond Ratings 显示文摘 | Aaron D Crabtree Duane M Brandon John J Maher | 2006 | Advances in Accounting2006，22，6： | 1 |
| 14 | Vegetation uptake of nitrogen and base cations in China and its role in soil acidification显示文摘 | Duan L Huang Y M Hao J M | 2004 | Science of the Total Environment2004，330，： | 1 |
| 15 | Microdiffraction Used to Study Domain Switching of Ferroelectric Thin Films 显示文摘 | Eatough M O Rodriquez M A Duane D | 1995 | The Rigaku Journal1995，12，2： | 1 |
| 16 | Human bone marrow stein cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the isehemic brain of rats显示文摘 | Zhao LR Duan WM Reyes M | 2002 | Exp Neurol2002，174，1： | 1 |
| 17 | Integrated flight propulsion control system design based on a centralized approach显示文摘 | Sanjay G Duane L M Bullard R E | 1991 | Journal of Guidance Control and Dynamics1991，14，1： | 1 |
| 18 | Highly polarized photoluminescence and photodetection from single indium phosphide nanowires 显示文摘 | Wang J F Gudiksen M S Duan X F Cui Y Lieberet H M | 2001 | Science2001，293，5534： | 1 |
| 19 | Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats显示文摘 | Zhao LR Duan WM Reyes M | 2002 | Exp Neurol2002，174，1： | 1 |
| 20 | Synthesis and properties of the geometrically controlled mixed-valence tetrahedral Ru^Ⅱ2 Ru^Ⅲ2 L6 cluster 显示文摘 | Cai P Li M Duan C | 2005 | Eur J Inorg Chem2005，，： | 1 |
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