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| 1 | Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer’s disease: randomised, double-blind, placebo-controlled, first-in-human study显示文摘 | Bengt Winblad Niels Andreasen Lennart Minthon Annette Floesser Georges Imbert Thomas Dumortier R Paul Maguire Kaj Blennow Joens Lundmark Matthias Staufenbiel Jean-Marc Orgogozo Ana Graf | 2012 | Lancet Neurology2012,,7: | 3 |
| 2 | Natural history, treatment and prevention of hepatitis C recurrence after liver transplantation: Past, present and future显示文摘Hepatitis C virus(HCV)-related liver disease, including cirrhosis and hepatocellular carcinoma is the main indication for liver transplantation(LT) worldwide. Posttransplant HCV re-infection is almost universal and results in accelerated progression from acute hepatitis to chronic hepatitis, and liver cirrhosis. Comprehension and treatment of recurrent HCV infection after LT have been major issues for all transplant hepatologists and transplant surgeons for the last decades. The aim of this paper is to review the evolution of our knowledge on the natural history of HCV recurrence after LT, including risk factors for disease progression, and antiviral therapy. We will focus our attention on possible ways(present and future) to improve the final longterm results of LT for HCV-related liver disease. | Jérme Dumortier Olivier Boillot Jean-Yves Scoazec | 2014 | World Journal of Gastroenterology2014,20,32: | 2 |
| 3 | 食管胶囊内镜与食管胃十二指肠内镜检查对门脉高压症的评价:一项性能和耐受性的前瞻性、对照研究显示文摘Background and study aims: Esophagogastroduodenoscopy (EGD) is the most effective method for examining the upper gastrointestinal tract, and particularly for evaluating portal hypertion cirrhotic patients, especially for screening purposes. The aim of this study was to assess the feasibility, safety, accuracy, and tolerance of PillCam ESO capsule endoscopy for this indication. Patients and methods: In this prospective study, unsedated EGD and capsule endoscopy examinations were conducted on the same day in cirrhotic patients at the time of diagnosis. The patients quantified the tolerability (relative to pain, nausea, choking sensations, etc.) of the two procedures using a 100 mm visual analogue scale. The time required for the recording and for diagnosis with the capsule examination were documented, as were the patients’ preferences in comparison with EGD. Two independent endoscopists blinded to the EGD diagnoses assessed the diagnostic accuracy of the images obtained. Results: Twenty-one patients were included in the study (mean age 62, mean Model for End-Stage Liver Disease score 10.5, mean Child-Pugh score 7.3). The procedure was safe. One patient was unable to swallow the capsule. The mean recording time was 213 s (range 6-1200 s); the procedure accurately assessed the presence or absence of esophageal varices in 16 of 19 patients (84.2 % ); and it correctly indicated a need for primary prophylaxis (esophageal varices of grade 2 or more and/or red signs) in 100 % of cases. The tolerability of the capsule endoscopy examination was significantly better, and all of the patients preferred capsule endoscopy to EGD (which was transnasal in 11 patients). Conclusions: Capsule endoscopy was feasible, safe, accurate, highly acceptable, and preferred by cirrhotic patients undergoing screening for portal hypertension. This new technique requires further and more extensive evaluation, as well as assessment of its cost-effectiveness. | Lapalus M.-G. Dumortier J. Fumex F. 纪泛扑 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006,2,5: | 2 |
| 4 | Safety and efficacy of protease inhibitors to treat hepatitis C after liver transplantation: A multicenter experience显示文摘 | Audrey Coilly Bruno Roche Jér?me Dumortier Vincent Leroy Danielle Botta-Fridlund Sylvie Radenne Georges-Philippe Pageaux Si-Nafaa Si-Ahmed Olivier Guillaud Teresa Maria Antonini Stéphanie Ha?m-Boukobza Anne-Marie Roque-Afonso Didier Samuel Jean-Charles Du | 2014 | Journal of Hepatology2014,,1: | 2 |
| 5 | Assessment of a new in vitro maturation system for mouse and human cumulus - enclosed oocytes:three - dimensional prematuration culture in the presence of a phosphodiesterase 3 - inhibitor 显示文摘 | Vanhoutte L Nogueira D Dumortier F | 2009 | Human Reproduction2009,24,8: | 1 |
| 6 | Eversion thrombectomy for portal vein thrombosis during liver transplantation显示文摘 | Dumortier J Czyglik O Poncet G | 2002 | Am J Transplant2002,2,10: | 1 |
| 7 | Quadratic Lienard Equations with Quadratic Damping显示文摘 | Dumortier Freddy Li Chengzhi | 1997 | Journal of Differential Equations1997,1391,: | 1 |
| 8 | Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication显示文摘 | Van-Mierlo G J Boonman Z F Dumortier H M | 2004 | J Immunol2004,173,11: | 1 |
| 9 | Generic technologies for single and multi-document summarization显示文摘 | MOENS M-F ANGHELUTA R DUMORTIER J | 2005 | Information Processing and Management2005,41,: | 1 |
| 10 | Generic 3-parameter family of planar vector fields, unfolding of saddle,focus and elliptic singularities with nilpotent limear parts显示文摘 | Dumortier F Roussarie R Sotomayor J | 1991 | Lecture Notes in Math1991,1480,: | 1 |
| 11 | Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells显示文摘 | Ivan Maillard Ute Koch Alexis Dumortier Olga Shestova Lanwei Xu Hong Sai Seth E. Pross Jon C. Aster Avinash Bhandoola Freddy Radtke Warren S. Pear | 2008 | Cell Stem Cell2008,,4: | 1 |
| 12 | Geometric Singular Perturbation Theory Beyond Normal Hyperbolicity显示文摘 | F Dumortier B Roussarie | 1998 | The IMA volumes in Mathematics and its Applications1998,122,: | 1 |
| 13 | Diagnosis and treatment of biliary obstruction caused by portal cavernoma显示文摘 | Dumortier J Vailant E Boillot O | 2003 | Endoscopy2003,35,5: | 1 |
| 14 | Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells显示文摘 | Ivan Maillard Ute Koch Alexis Dumortier Olga Shestova Lanwei Xu Hong Sai Seth E. Pross Jon C. Aster Avinash Bhandoola Freddy Radtke Warren S. Pear | 2008 | Cell Stem Cell2008,,4: | 1 |
| 15 | Perturbations from an elliptic hamiltonian of degree four I: saddle loop and two saddle cycle 显示文摘 | Dumortier F Li C Z | 2001 | J Diff Eq2001,176,: | 1 |
| 16 | Defferent mechanisms op- erating During different critieal time windows reduee rat fetal beta cell mass due to a matemal low- proteinor low-energy diet 显示文摘 | Dumortier O Blondeau B Duvillie B | 2007 | Diabetolo- gia2007,50,12: | 1 |
| 17 | Theoretical considerations on the modelling of transport in a three-phase electrode and application to a proton conducting solid oxide electrolysis cell 显示文摘 | Dumortier M Sanchez J Keddam M | 2012 | International Journal of Hydrogen Energy2012,37,11: | 1 |
| 18 | Ikaros regu-lates neutrophil differentiation 显示文摘 | Dumortier A Kirstetter P Kastner P | 2003 | Blood2003,101,6: | 1 |
| 19 | Balance of Substrate Oxidation during Submaximal Exercise in Lean and Obese People显示文摘 | PEREZ-MARTIN A DUMORTIER M RAYNAUD E | 2001 | Diabetes Metab2001,27,41: | 1 |
| 20 | Jaggedl-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation显示文摘 | Mancini SJC Mantei N Dumortier A | 2005 | Blood2005,105,62: | 1 |