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| 1 | Nationwide trends and predictors of inpatient mortality in 83884 transjugular intrahepatic portosystemic shunt显示文摘AIM: To evaluate and validate the national trends and predictors of in-patient mortality of transjugular intrahepatic portosystemic shunt(TIPS) in 15 years.METHODS: Using the National Inpatient Sample which is a part of Health Cost and Utilization Project, we identified a discharge-weighted national estimate of 83884 TIPS procedures performed in the United States from 1998 to 2012 using international classification of diseases-9 procedural code 39.1. The demographic, hospital and co-morbility data were analyzed using a multivariant analysis. Using multi-nominal logistic regression analysis, we determined predictive factors related to increases in-hospital mortality. Comorbidity measures are in accordance to the Comorbidity Software designed by the Agency for Healthcare Research and Quality.RESULTS: Overall, 12.3% of patients died during hospitalization with downward trend in-hospitalmortality with the mean length of stay of 10.8 ± 13.1 d. Notable, African American patients(OR = 1.809 vs Caucasian patients, P < 0.001), transferred patients(OR = 1.347 vs non-transferred, P < 0.001), emergency admissions(OR = 3.032 vs elective cases, P < 0.001), patients in the Northeast region(OR = 1.449 vs West, P < 0.001) had significantly higher odds of inhospital mortality. Number of diagnoses and number of procedures showed positive correlations with in-hospital death(OR = 1.249 per one increase in number of procedures). Patients diagnosed with acute respiratory failure(OR = 8.246), acute kidney failure(OR = 4.359), hepatic encephalopathy(OR = 2.217) and esophageal variceal bleeding(OR = 2.187) were at considerably higher odds of in-hospital death compared with ascites(OR = 0.136, P < 0.001). Comorbidity measures with the highest odds of in-hospital death were fluid and electrolyte disorders(OR = 2.823), coagulopathy(OR = 2.016), and lymphoma(OR = 1.842).CONCLUSION: The overall mortality of the TIPS procedure is steadily decreasing, though the length of stay has remained relatively constant. Specific patient ethnicity, location, transfer status, primary diagnosis and comorbidities correlate with increased odds of TIPS in-hospital death. | Edward Wolfgang Lee Andrew Kuei Sammy Saab Ronald W Busuttil Francisco Durazo Steven-Huy Han Mohamed M El-Kabany Justin P Mc Williams Stephen T Kee | 2016 | World Journal of Gastroenterology2016，22，25： | 7 |
| 2 | Gastric intestinal metaplasia is associated with gastric dysplasia but is inversely correlated with esophageal dysplasia显示文摘AIM To determine which clinical factors might be associated with gastric intestinal metaplasia(IM) in a North American population.METHODS Pathology and endoscopy databases at an academicmedical center were reviewed to identify patients with and without gastric IM on biopsies for a retrospective cohort study. Patient demographics, insurance status, and other clinical factors were reviewed.RESULTS Four hundred and sixty-eight patients with gastric IM(mean age: 61.0 years ± 14.4 years, 55.5% female) and 171 without gastric IM(mean age: 48.8 years ± 20.8 years, 55.0% female) were compared. The endoscopic appearance of atrophic gastritis correlated with finding gastric IM on histopathology(OR = 2.05, P = 0.051). Gastric IM was associated with histologic findings of chronic gastritis(OR = 2.56, P < 0.001), gastric ulcer(OR = 6.97, P = 0.015), gastric dysplasia(OR = 6.11, P = 0.038), and gastric cancer(OR = 6.53, P = 0.027). Histologic findings of Barrett's esophagus(OR = 0.28, P = 0.003) and esophageal dysplasia(OR = 0.11, P = 0.014) were inversely associated with gastric IM. Tobacco use(OR = 1.73, P = 0.005) was associated with gastric IM.CONCLUSION Patients who smoke or have the endoscopic finding of atrophic gastritis are more likely to have gastric IM and should have screening gastric biopsies during esophagogastroduodenoscopy(EGD). Patients with gastric IM are at increased risk for having gastric dysplasia and cancer, and surveillance EGD with gastric biopsies in these patients might be reasonable. | Justin M Gomez James T Patrie Wissam Bleibel Jeanetta W Frye Bryan G Sauer Vanessa M Shami Edward B Stelow Christopher A Moskaluk Andrew Y Wang | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，2： | 3 |
| 3 | Do viscous polysaccharides slow absorption by inhibiting diffusion or convection?显示文摘 | Edwards C A Johnson I T Read N W | 1988 | European Journal of Clinical Nutrition1988，42，： | 1 |
| 4 | Increasing scientific confidence in adverse outcome pathways:application of tailored Bradford - Hill considerations for evaluating weight of evidence 显示文摘 | BECKER R A ANKLEY G T EDWARDS S W | 2015 | Regul Toxicol Pharmacol2015，72，3： | 1 |
| 5 | 13C response surface resolves humidity and temperature signals in trees 显示文摘 | EDWARDS T GRAF W TRIMBORN P | 2000 | Geochim Cosmochim Acta2000，64，： | 1 |
| 6 | OMEGA EP high-energy petawatt laser: progress and prospects显示文摘 | D N Maywar J H Kelly L J Waxer S F B Morse I A Begishev J Bromage C Dorrer J L Edwards L Folnsbee M J Guardalben S D Jacobs R Jungquist T J Kessler R W Kidder B E Kruschwitz S J Loucks J R Marciante R L McCrory D D Meyerhofer A V Okishev J B Oliver G Pien | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 7 | A biomarker panel for peripheral arterial disease显示文摘 | Fung E T Wilson A M Zhang F Harris N Edwards K A Olin J W | 2008 | Vasc Med2008，13，： | 1 |
| 8 | Nonlinear aeroelasticity显示文摘 | Dowell E Edward J Strganac T W | 2003 | Journal of Aircraft2003，40，3： | 1 |
| 9 | Analysis of capacity fade in a lithium ion battery 显示文摘 | ANDREW T S CHARLES E H PALPH E W EDWARD P G | | Journal of Power Sources0，150，4： | 1 |
| 10 | Community genomics among stratified microbial assemblages in the ocean's interior显示文摘 | DeLong E F Preston C M Mincer T Rich V Hallam S J Frigaard N U Martinez A Sullivan M B Edwards R Brito B R Chisholm S W Karl D M | | 0，，5760： | 1 |
| 11 | Small-Angle Neutron Scattering From a Polystyrene-b-Poly (methyl methacrylate) Diblock Copolymer in a Selective Solvent显示文摘 | Edwards C J C Richards R W Stepto R F T | 1986 | Polymer1986，27，5： | 1 |
| 12 | The microbiology of asthma显示文摘 | Edwards M R Bartlett N W Hussell T Openshaw P Johnston S L | 2012 | Nat Rev Microbiol2012，10，： | 1 |
| 13 | Multiplex PCR- DNA probe assay for the detection of pathogenic Escherichia coli 显示文摘 | LEIGH W EDWARD T HEIDI S | 2005 | Journal of Microbiological Methods2005，60，： | 1 |
| 14 | Trace fossils in the Lower Beacon sediments (Devonian),Darwin mountains,Southern Victoria Land,Antarctica显示文摘 | Gevers T W Frakes L A Edwards L N | 1971 | Journal of Paleontology1971，45，1： | 1 |
| 15 | Temperature-independent du- al variation in soil respiration observed from atemperature deciduous forest显示文摘 | Liu Q Edwards N T Post W M | 2006 | Global Change Biology2006，12，： | 1 |
| 16 | A biomechanical study of the fatigue characteristics of thorscolumbar fixation implants in a calf spine model显示文摘 | WITTENBERG R H SHEA M EDWARDS W T | 1992 | Spine1992，17，： | 1 |
| 17 | Surgical management of renal artery aneurysms显示文摘 | English W P Pearce J D Craven T E Wilson D B Edwards M S Ayerdi J | 2004 | J Vasc Surg2004，40，： | 1 |
| 18 | Incidence and size of patent foramen ovale during the first 10 decades of life: an autopsy study of 965 normal hearts 显示文摘 | Hagen P T Scholz D G Edwards W D | 1984 | Mayo Clin Proc1984，59，1： | 1 |
| 19 | Universal alignment probabilities and subset selection for ordinal optimization显示文摘 | Edward T W Ho Y C | 1997 | Journal of Optimization Theory and Applications1997，93，3： | 1 |
| 20 | A survey of the Brassica rapa genome by BAC-end sequence analysis and comparison with Arabidopsis thaliana显示文摘 | Hong C P Plaha P Koo D H Yang T J Choi S R Lee Y K Uhm T Bang J W Edwards D Bancroft Ⅰ Park B S Lee J Lim Y P | | 0，，： | 1 |
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