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    题名 作者 年代 出处 被引量
1Association of serum lipid levels with diabetic retinopathy显示文摘AIM: To assess the association between serum lipids and diabetic retinopathy (DR). · METHODS: Sixty -one diabetic patients without retinopathy (NDR), 55 diabetic patients with non - proliferative retinopathy (NPDR) and 75 diabetic patients with proliferative retinopathy (PDR) according to ETDRS grading scale were enrolled in this study. Total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and triglyceride values were compared between the groups. ·RESULTS: The groups were well-balanced in terms of age and gender (P =0.071, P =0.265 respectively). The mean HbA1c values were significantly lower in NDR group than the NPDR and PDR groups(P =0.004, P =0.009 respectively). Mean total cholesterol, triglyceride, LDL, HDL and VLDL levels were not significantly different between the groups (P =0.693, P =0.774, P =0.644, P = 0.910 and P =0.967 respectively, one way ANOVA). Mean total cholesterol, triglyceride, LDL, HDL and VLDL levels were not significantly different between the patients with ME and patients without ME(P =0.622, P =0.113, P =0.955, P =0.735 and P =0.490 respectively, t -test). The mean blood glucose significantly correlated with total cholesterol (r =0.173, P =0.017) and LDL (r =0.190, P = 0.008). The mean HbA1c significantly correlated with total cholesterol (r =0.158, P =0.030) and triglyceride (r =0.148, P =0.042). ·CONCLUSION: Serum lipid levels were not significantly associated with the severity of DR or existence of ME despite the significant correlation between the mean blood glucose, HbA1c and total cholesterol.Ebru Nevin Cetin Yunus Bulgu Seyfullah Ozdemir Senay Topsakal Fulya Akln Hulya Aybek Cem Ylldlrlm 2013International Journal of Ophthalmology(English edition)2013,6,3:14
2Clinical role and importance of fluorescence in situ hybridization method in diagnosis of H pylori infection and determination of clarithromycin resistance in H pylori eradication therapy显示文摘H pylori is etiologically associated with gastritis, gas-tric and duodenal ulcers, gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. Eradicating H pylori may convert rapidly the outcome of related diseases with the use of more accurate diagnostic molecular tests. Indeed some of the tests cannot give the evidence of current infection; H pylori can be detected by noninvasive and invasive methods, the latter requiring an endoscopy. Eradication failure is a big problem in H pylori infection. Recently, clarithromycin resistance in H pylori strains is increasing and eradicati-on therapy of this bacterium is becoming more difficult. Molecular methods have frequently been applied besides phenotypic methods for susceptibility testing to detect clarithromycin resistance due to mutations in the 2143 and 2144 positions of 23S rRNA gene. Fluorescence in situ hybridization (FISH) method on paraffin embedded tissue is a rapid, accurate and cost-effective method for the detection of H pylori infection and to determine clarithromycin resistance within three hours according to the gold standards as a non-culture method. This method can also be applied to fresh biopsy samples and the isolated colonies from a culture of H pylori, detecting both the culturable bacillary forms and the coccoid forms of H pylori, besides the paraffin embedded tissue secti-ons. This technique is helpful for determining the bac-terial density and the results of treatment where clarith-romycin has been widely used in populations to increase the efficacy of the treatment and to clarify the treatment failure in vitro.zlem Yilmaz Ebru Demiray 2007World Journal of Gastroenterology2007,13,5:10
3Unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis显示文摘AIM: To investigate the prevalence and implications of unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis. METHODS: The demographic and histopathological data of 1621 patients (≥ 16 years-old) who underwent appendectomy to treat an initial diagnosis of acute appendicitis between January 1999 and November 2011 were retrospectively assessed. Microscopic findings were used to classify the patients under six categories: appendix vermiformis, phlegmonous appendicitis, gan- grenous appendicitis, perforated appendicitis, supurative appendicitis, and unusual histopathologic findings. The demographic and clinicopathologic characteristics of patients with unusual histopathologic findings were evaluated in detail, and re-analysis of archived resected appendix specimens was carried out. RESULTS: A total of 912 males and 709 females, from16 to 94 years old, were included in the study and comprised 789 cases of suppurative appendicitis, 370 cases of appendix vermiformis, 243 cases of perforated gangrenous appendicitis, 53 cases of flegmaneous appendicitis, 32 cases of gangrenous appendicitis, and 134 (8.3%) cases of unusual histopathological findings. The unusual histopathological findings included fibrous obliteration (n = 62), enterobius vermicularis (n = 31), eosinophilic infiltration (n = 10), mucinous cystadenoma (n = 8), carcinoid tumor (n = 6), granulomatous inflammation (n = 5), adenocarcinoma (n = 4; one of them mucinous), and mucocele (n = 3), adenomatous polyp (n = 1), taenia sup (n = 1), ascaris lumbricoides (n = 1), appendiceal diverticula (n = 1), and B cell non-hodgkin lymphoma (n = 1). None of the 11 patients with subsequent diagnosis of tumor were suspected of cancer prior to the appendectomy. CONCLUSION: Even when the macroscopic appearance of appendectomy specimens is normal, histopathological assessment will allow early diagnosis of many unusual diseases.Mehmet Yilmaz Sami Akbulut Koray Kutluturk Nurhan Sahin Ebru Arabaci Cengiz Ara Sezai Yilmaz 2013World Journal of Gastroenterology2013,19,25:9
4Comparison of subconjunctivally injected bevacizumab, ranibizumab, and pegaptanib for inhibition of corneal neovascularization in a rat model显示文摘AIM: To compare the efficacies of subconjunctival bevacizumab, ranibizumab, and pegaptanib sodium injections for the inhibition of corneal neovascularization in an experimental rat model. METHODS: Sixteen corneas of 16 rats were chemically cauterized and randomized into four groups: bevacizumab group that treated with 0.05mL/1.25mg bevacizumab, ranibizumab group that treated with 0.05mL/0.5mg ranibizumab, pegaptanib group that treated with 0.05mL/0.15mg pegaptanib sodium, and control group that treated with 0.05mL saline solution. Digital photographs of the corneas were taken and analyzed using an image analysis software program. All corneas were excised and examined histologically on the 15 th day. RESULTS: Each treatment group had significantly less neovascularized corneal areas and fewer blood vessels than the control group (all P <0.05). In addition, bevacizumab group had significantly less neovascu-larized corneal areas and fewer blood vessels than ranibizumab and pegaptanib groups (both P <0.05). However, there was no significant difference between the ranibizumab and pegaptanib groups regarding percentage of neovascularized corneal areas and number of blood vessels (both P >0.05). CONCLUSION: Subconjunctival bevacizumab, ranibiz-umab, and pegaptanib sodium were effective with no corneal epitheliopathy for inhibiting corneal neovascularization after corneal burn in rats .Bevacizumab was more effective than ranibizumab and pegaptanib sodium.Ebru Eren Akar Veysi ner Cem Küükerdnmez Yonca Aydin Akova 2013International Journal of Ophthalmology(English edition)2013,6,2:9
5Gastric polypoid lesions:Analysis of 150 endoscopic polypectomy specimens from 91 patients显示文摘AIM: To analyze gastric polypoid lesions in our patientpopulation with respect to histopathologic features and demographic, clinical, and endoscopic characteristics of patients.METHODS: Clinical records and histopathologic reports of patients with gastric polypoid lesions were analyzed retrospectively. All lesions had been totally removed by either endoscopic polypectomy or hot biopsy forceps. The histopathologic slides were re-evaluated by the same histopathologist.RESULTS: One-hundred and fifty gastric polypoid lesions were identified in 91 patients. There were 53 (58%) women and 38 (42%) men with a median age of 53 (range, 31 to 82) years. The most frequent presenting symptom was dyspepsia that was observed in 35 (38.5%) patients.Symptoms were mostly related to various associated gastric abnormalities such as chronic gastritis or H pylori infection rather than polypoid lesion itself. Polypoid lesions were commonly located in the antrum followed by cardia. Out of 150 lesions, 80 (53%) had the largest dimensions less than or equal to 5 mm and only 7 were pedunculated. The frequencies of hyperplastic polyps, foveolar hyperplasia, and fundic gland polyps were 46%, 18%, and 14% respectively.We also detected gastritis varioliformis in 12 specimens,lymphoid follicles in 9, 4 adenomatous polyps in 4, polypoid lesions with edematous mucosa in 4, inflammatory polyps in 3, and carcinoid tumor in 1. Adenomatous changes were observed within two hyperplastic polyps and low grade dysplasia in one adenoma. Histopathologic evaluation of the surrounding gastric mucosa demonstrated chronic gastritis in 72 (79%) patients and H pylori infection in 45 (49%).CONCLUSION: Hyperplastic polyps are the most frequently encountered subtype of gastric polypoid lesions. They are usually associated with chronic gastritis or H pylori gastritis. Contrary to the previous belief, they may harbour adenomatous changes or dysplastic foci.Therefore, endoscopic polypectomy seems as a safe and fast procedure for both diagnosis and treatment of gastric polypoid lesions at the same session. In addition,edematous mucosa may appear misleadingly as a polypoid lesion in some instances and it can be ruled out only by histopathologic examination.Rasim Gencosmanoglu Ebru Sen-Oran Ozlem Kurtkaya-Yapicier Erol Avsar Aydin Sav Nurdan Tozun 2003World Journal of Gastroenterology2003,9,10:8
6Importance of antimicrobial susceptibility testing for the management of eradication in Helicobacter pylori infection显示文摘The management of Helicobacter pylori(H. pylori) infection treatment differs from the common treatment protocol for other infectious diseases. Because culture-or molecular-guided approaches face several practical issues, such as the invasive procedures required to obtain gastric biopsy specimens and the lack of availability of routine laboratory testing in some places, H. pylori treatment includes the administration of two or three empirically selected antibiotics combined with a proton pump inhibitor rather than evidence-based eradication treatment. The efficacy of empirical therapy is decreasing, mostly due to increasing multiple resistance. Multiresistance to levofloxacin, clarithromycin, and metronidazole, which are commonly used in empirical treatments, appears to have increased in many countries. Mutations play a primary role in the antimicrobial resistance of H. pylori, but many different mechanisms can be involved in the development of antibiotic resistance. Determining and understanding these possible mechanisms might allow the development of new methods for the detection of H. pylori and the determination of antimicrobial resistance. A treatment based on the detection of antimicrobial resistance is usually more effective than empirical treatment. Nevertheless, such an approach before treatment is still not recommended in the Maastricht guidelines due to the difficulty associated with the routine application of available cultureor molecular-based susceptibility tests, which are usually administered in cases of treatment failure. The management of first and rescue treatments requires further research due to the steadily increase in antimicrobial resistance.Nazli Arslan ozlem Yilmaz Ebru Demiray-Gürbüz 2017World Journal of Gastroenterology2017,23,16:7
7Clinical and hemodynamic profiles of elderly patients with pulmonary arterial hypertension: a single center, prospective study显示文摘sPulmonary 动脉的高血压(哼) 以前被认为主要影响幼仔的病,但是现在,它逐渐地也被认出在老。这研究的目的是比较诊断与的老对更年轻的病人的特征,并且定义影响他们的长期的 survival.MethodsIn 的预示的因素哼这未来的、单个中心研究,临床, echocardiographic ,血液动力学的特征,并且结果更年轻( 18-65 年)并且老( 65 年)有 precapillary 的权威的诊断的病人哼 119 个病人全部的 compared.ResultsA 在这研究被分析;43 是老的(吝啬的年龄:71.5 ? 灡牰灯楲瑡 ? 慣摮摩瑡 ? 景瀠汵潭慮祲愠瑲牥慩? 票数瑲湥楳湯 ? 灳 ' 虝娹娆 _ 敨慲祰椠 ? 汥敤汲 ? 慰楴湥獴眠瑩 ? 異浬湯牡 ?Ebru Ozpelit Bahri Akdeniz Dilek Sezgin Can Sevinc Kemal Can Tertemiz Mehmet Emre Ozpelit Mustafa Baris Nezihi Baris 2017Journal of Geriatric Cardiology2017,14,1:5
8Voltage gated calcium channel antibody-related neurological diseases显示文摘Voltage gated calcium channel(VGCC) antibodies are generally associated with Lambert-Eaton myasthenic syndrome. However the presence of this antibody has been associated with paraneoplastic as well as nonparaneoplastic cerebellar degeneration. Most patients with VGCC-antibody-positivity have small cell lung cancer(SCLC). Lambert-Eaton myasthenic syndrome(LEMS)is an autoimmune disease of the presynaptic part of the neuromuscular junction. Its classical clinical triadis proximal muscle weakness, areflexia and autonomic dysfunction. Fifty to sixty percent of LEMS patients have a neoplasia, usually SCLC. The co-occurrence of SCLC and LEMS causes more severe and progressive disease and shorter survival than non-paraneoplastic LEMS. Treatment includes 3,4 diaminopyridine for symptomatic purposes and immunotherapy with prednisolone, azathioprine or intravenous immunoglobulin in patients unresponsive to 3,4 diaminopyridine. Paraneoplastic cerebellar degeneration(PCD) is a syndrome characterized with severe, subacute pancerebellar dysfunction. Serum is positive for VGCC antibody in 41%-44% of patients, usually with the co-occurrence of SCLC. Clinical and electrophysiological features of LEMS are also present in 20%-40% of these patients. Unfortunately, PCD symptoms do not improve with immunotherapy. The role of VGCC antibody in the immunopathogenesis of LEMS is well known whereas its role in PCD is still unclear. All patients presenting with LEMS or PCD must be investigated for SCLC.Can Ebru Bekircan-Kurt Eda DerleÇiftçi Aslι Tuncer Kurne Banu Anlar 2015World Journal of Clinical Cases2015,3,3:5
9Adipokines and ghrelin in gastric cancer cachexia显示文摘AIM:To investigate the roles of the adipocytokines,ghrelin and leptin in gastric cancer cachexia. METHODS:Resistin,ghrelin,leptin,adiponectin,insulin and insulin-like growth factor(IGF-Ⅰ),were measured in 30 healthy subjects,and 60 gastric cancer patients of which 30 suffered from cancer-induced cachexia and 30 served as a control group. The relationships between hormones,body mass index(BMI) loss ratio,age,gender,and Glasgow Prognostic Score(GPS) were investigated. RESULTS:Cachexia patients had higher tumor stage and GPS when compared with non-cachexia patients(P < 0.05). Ghrelin,resistin,leptin,adiponectin and IGF-Ⅰ,showed a significant correlation with BMI loss ratio and GPS(P < 0.05). A strong correlation was seen between GPS and BMI loss(R = -0.570,P < 0.0001). Multivariate analysis indicated that BMI loss was significantly independent as a predictor of ghrelin,resistin,leptin and IGF-Ⅰ(P < 0.05). Existence of an important significant relationship between resistin and insulin resistance was also noted. CONCLUSION:These results showed that serum ghrelin,leptin,adiponectin,and IGF-Ⅰ play important roles in cachexia-related gastric cancers. No relationshipwas found between resistin and cancer cachexia. Also,because of the correlation between these parameters and GPS,these parameters might be used as a predictor factor.Mustafa Kerem Zafer Ferahkose Utku Tonguc Yilmaz Hatice Pasaoglu Ebru Ofluoglu Abdulkadir Bedirli Bulent Salman Tevfik Tolga Sahin Murat Akin 2008World Journal of Gastroenterology2008,14,23:4
10Kefir treatment ameliorates dextran sulfate sodium-induced colitis in rats显示文摘AIM: To investigate the preventive effect of kefir on colitis induced with dextran sulfate sodium(DSS) in rats.METHODS: Twenty-four male Wistar-albino rats were randomized into four groups: normal control,kefircontrol,colitis,and kefir-colitis groups. Rats in the normal and kefir-control groups were administered tap water as drinking water for 14 d. Rats in the colitis and kefir-colitis groups were administered a 3% DSS solution as drinking water for 8-14 d to induce colitis. Rats in the kefir-control and kefir-colitis groups were administered 5 m L kefir once a day for 14 d while rats in the normal control and colitis group were administered an identical volume of the placebo(skim milk) using an orogastric feeding tube. Clinical colitis was evaluated with reference to the disease activity index(DAI),based on daily weight loss,stool consistency,and presence of bleeding in feces. Rats were sacrificed on the 15 th day,blood specimens were collected,and colon tissues were rapidly removed. Levels of myeloperoxidase(MPO),tumor necrosisfactor(TNF)-α,interleukin(IL)-10,malondialdehyde,and inducible nitric oxide synthase(i NOS) were measured in colon tissue.RESULTS: The DAI was lower in the kefir-colitis group than in the colitis group(on the 3rd and 5th days of colitis induction; P < 0.01). The DAI was also significantly higher in the colitis group between days 2 and 6 of colitis induction when compared to the normal control and kefir-control groups. The DAI was statistically higher only on the 6th day in the kefircolitis group when compared to that in the normal control groups. Increased colon weight and decreased colon length were observed in colitis-induced rats. Mean colon length in the colitis group was significantly shorter than that of the kefir-control group. Kefir treatment significantly decreased histologic colitis scores(P < 0.05). MPO activity in the colitis group was significantly higher than in the kefir-control group(P < 0.05). Kefir treatment significantly reduced the DSS colitis-induced TNF-α increase(P < 0.01). No statistically significant differences were observed among groups for IL-10 and MDA levels. Colon tissue i NOS levels in the colitis group were significantly higher than those in the control and kefir-colitis groups(P < 0.05).CONCLUSION: Kefir reduces the clinical DAI and histologic colitis scores in a DSS-induced colitis model,possibly via reduction of MPO,TNF-α,and i NOS levels.Altug Senol Mehmet Isler Recep Sutcu Mete Akin Ebru Cakir Betul M Ceyhan M Cem Kockar 2015World Journal of Gastroenterology2015,21,46:3
11Evaluation of an erosion-sediment transport model for a hillslope using laboratory flume data显示文摘Climate change can escalate rainfall intensity and cause further increase in sediment transport in arid lands which in turn can adversely affect water quality. Hence, there is a strong need to predict the fate of sediments in order to provide measures for sound erosion control and water quality management. The presence of microtopography on hillslopes influences processes of runoff generation and erosion, which should be taken into account to achieve more accurate modelling results. This study presents a physically based mathematical model for erosion and sediment transport coupled to one-dimensional overland flow equations that simulate rainfall-runoff generation on the rill and interrill areas of a bare hillslope. Modelling effort at such a fine resolution considering the flow connection between interrill areas and rills is rarely verified. The developed model was applied on a set of data gathered from an experimental setup where a 650 cm×136 cm erosion flume was pre-formed with a longitudinal rill and interrill having a plane geometry and was equipped with a rainfall simulator that reproduces natural rainfall characteristics. The flume can be given both longitudinal and lateral slope directions. For calibration and validation, the model was applied on the experimental results obtained from the setup of the flume having 5% lateral and 10% longitudinal slope directions under rainfall intensities of 105 and 45 mm/h, respectively. Calibration showed that the model was able to produce good results based on the R2(0.84) and NSE(0.80) values. The model performance was further tested through validation which also produced good statistics(R2=0.83, NSE=0.72). Results in terms of the sedigraphs, cumulative mass curves and performance statistics suggest that the model can be a useful and an important step towards verifying and improving mathematical models of erosion and sediment transport.Anya Catherine CARGUELLES MinJae JUNG Kristine Joy BMALLARI GiJung PAK Hafzullah AKSOY Levent M KAVVAS Ebru ERIS JaeYoung YOON YoungJoon LEE SeonHwa HONG 2014Journal of Arid Land2014,6,6:3
12Characterization of H3K9me3- and H4K20me3-associated circulating nucleosomal DNA by high-throughput sequencing in colorectal cancer显示文摘Ugur Gezer Duran üstek Ebru E. Y?rüker Aris Cakiris Neslihan Abaci Gloria Leszinski Nejat Dalay Stefan Holdenrieder 2013Tumor Biology2013,,1:2
13Determination of Elements by Atomic Absorption Spectrometry in Medicinal Plants Employed to Alleviate Common Cold Symptoms显示文摘Eleven important medicinal plants generally used by the people of Turkey for the treatment of common cold have been studied for their mineral contents.Eleven minor and major elements(essential,non-essential and toxic)were identified in the Asplenium adiantum-nigrum L.,Althaea officinalis L.,Verbascum phlomoides L.,Euphorbia chamaesyce L.,Zizyphus jujube Miller,Peganum harmala L.,Arum dioscoridis Sm.,Sambucus nigra L.,Piper longum L.,Tussilago farfara L.and Elettaria cardamomum Maton by employing flame atomic absorption and emission spectrometry and electro-thermal atomic absorption spectrometry.Microwave digestion procedure for total concentration was applied under optimized conditions for dissolution of medicinal plants.Plant based biological certified reference materials(CRMs)served as standards for quantification.These elements are found to be present in varying concentrations in the studied plants.The baseline data presented in this work can be used in understanding the role of essential,non-essential and toxic elements in nutritive,preventive and therapeutic properties of medicinal plants.F Zehra Kücükbay Ebru Kuyumcu 2014光谱学与光谱分析2014,34,9:2
14A Comparative Analysis of Disclosures in Annual Reports显示文摘Ebru Esendemirli 2014Journal of Modern Accounting and Auditing2014,10,4:2
15Antimicrobial resistance and underlying mechanisms in Staphylococcus aureus isolates显示文摘Objective: To investigate the antimicrobial susceptibility of 97 clinical Staphylococcus aureus(S. aureus) strains against 14 antimicrobials and corresponding resistance mechanisms.Methods: The antimicrobial susceptibility of the isolates was determined using a disk diffusion method and antimicrobial resistance genes were screened by polymerase chain reaction. Mutations responsible for ciprofloxacin and rifampicin resistance were investigated by polymerase chain reaction and DNA sequencing.Results: All isolates were found to be susceptible to vancomycin. Various rates of resistance to penicillin(83.5%), ampicillin(77.3%), erythromycin(63.9%), tetracycline(16.5%), amoxicillin/clavulanic acid(16.5%), ciprofloxacin(15.5%), trimethoprim/sulfamethoxazole(15.5%), oxacillin(13.4%), fusidic acid(12.4%), rifampin(6.2%), clindamycin(6.2%), gentamicin(6.2%) and mupirocin(5.2%) were determined. In addition,different combinations of resistance genes were identified among resistant isolates.Ciprofloxacin resistant isolates had mutations in codon 84(Ser84 Leu) and 106(Gly106 Asp) in the gyr A gene. Mutations in grl A were mostly related to Ser80 Phe substitution. Leu466 Ser mutation in the rpo B gene was detected in all rifampin resistant isolates. All methicillin resistant S. aureus isolates were SCCmec type V.Conclusions: In conclusion, it was determined that the isolates were resistant to different classes of antimicrobials at varying rates and resistance was mediated by different genetic mechanisms. Therefore, continuous monitoring of resistance in S. aureus strains is necessary to control their resistance for clinically important antimicrobials.Ebru Sebnem Yilmaz Ozkan Aslantas 2017Asian Pacific Journal of Tropical Medicine2017,10,11:2
16Structural and Optical Properties of Zinc Nitride Films Prepared by Pulsed Filtered Cathodic Vacuum Arc Deposition显示文摘多晶的锌氮化物电影被搏动的过滤 cathodic 真空弧免职(PFCVAD ) 在 Corning 7059 玻璃底层上扔。结晶的结构借助于 X 光衍射被学习。这些大小证明所有这些电影在立方的结构被使结晶,在比较喜欢的取向沿着(332 ) 并且(631 ) 方向。弱 XRD 信号显示出在非结晶的纸巾散布的小雏晶。crystallinity 的小改进与退火被观察。光参数象吸收那样,精力乐队差距, Urbach 尾巴,扑灭系数被决定了。Urbach 尾巴精力与在 500 ° C 退火一个小时被减少。精力乐队差距价值被发现被退火增加。SENADIM TUZEMEN Ebru KAVAK Hamide ESEN Ramazan 2007Chinese Physics Letters2007,24,12:2
17Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors显示文摘Tuba Kara Ebru Serinsoz Rabia Bozdogan Arpaci Ozlem Gubur Gulhan Orekici Alper Ata Tahsin Colak Ali Arican 2013Pathology - Research and Practice2013,,7:2
18Rank‐Order Tournaments and Incentive Alignment: The Effect on Firm Performance显示文摘JAYANT R. KALE EBRU REIS ANAND VENKATESWARAN 2009The Journal of Finance2009,,3:2
19Toxicity, inheritance and biochemistry of clofentezine resistance in Tetranychus urticae显示文摘这研究评估 two-spotted 蜘蛛螨的毒物学、生物化学的反应到 clofentezine 选择压力。在成年女性的 Tetranychus urticae 的死亡率取决于集中和 clofentezine 被发现对女性有效的增加的 clofentezine。与 clofentezine 每产生选择 12 次一次的 CUM 紧张的抵抗率从 1.28- 被增加到 105.27 褶层。有 clofentezine 的一些信仰神人协力合作说者的相互作用在 clofentezine 抵抗的 CLOF 12 紧张被分析。信仰神人协力合作说者没在 clofentezine 毒性上有效果。clofentezine 抵抗的 CLOF 12 紧张对 chlorpyrifos, abamectin, propargite, fenpyroximate 和 amitraz 显示出抵抗。到 clofentezine 的抵抗的继承的模式被发现不完全地主导、不由性的染色体遗传。Esterase 酶活动被胶化电气泳动和 microplate 读者方法两个都检测,当时谷胱甘肽 S-transferase (GST ) 和 monooxygenase (P450 ) 活动仅仅由 microplate 读者方法被检测。在选择时期期间, esterase, GST 和 P450 酶活动分别地从 7.69, 7.09 和 0.003 3 ~ 18.40, 13.11 和 0.003 7 毫光的 density/min/mg 蛋白质被提起。增加在 esterases 的乐队紧张被观察, esterase 酶可以在 T 在 clofentezine 抵抗起一个作用。urticae。Recep Ay Fatma Ebru Kara 2011Insect Science2011,18,5:2
20A laboratory modification to testicular sperm preparation technique improves spermatogenic cell yield显示文摘阴囊的精子抽取是过去常与 nonobstructive 精子缺乏在人发现 spermatogenic 房间的一个普通过程。biopsied 处理阴囊的纸巾的实验室需要细致地被表现获得房间的高收益。在这研究,在阴囊的活体检视以后切碎纸巾的有效性用组织学的评估被估计,作为在密度坡度 centrifugation 期间是 spermatogenic 房间的迁居上的剩余织物的可能的不利效果。当与精子一起在密度坡度媒介上放了时,我们的结果显示那阴囊的剩余纸巾洗,妨碍 spermatogenic cells’在 centrifugation 期间形成一个小团,并且因此损害 intracytoplasmic 精子注射过程。而从精子的恢复房间的吝啬的数字与剩余织物洗媒介(SWM ) 是 39.435 ±24.849,它尤其是更高(60.189 ±28.214 个房间) 在没有切碎的纸巾的 SWM。留下的织物没在组织学的节包含功能的生精的小管或 spermatogenic 房间。在结论,在切碎阴囊的织物不增加的 biopsied 以后的留下的剩余织物对 spermatogenic 房间检索的任何功能或细胞的贡献;事实上,它可以阻止通过坡度层移居在 centrifugation 和 spermatogenic 房间的原因损失期间形成一个小团在伴随的房间暂停接近细胞的元素。Sinan Ozkavukcu Ebru Ibis Sule Kizil Suheyla Isbacar Kaan Aydos 2014Asian Journal of Andrology2014,16,6:2
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