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| 1 | FAM19A4 is a novel cytokine ligand of formyl peptide receptor I (FPR 1) and is able to promote the migration and phagocytosis of macrophages显示文摘FAM19A4 是为有顺序类似 19 的家庭的缩写(chemokine (C-C 主题)-like) 成员 A4,它能分泌的蛋白质在正常纸巾在底层被表示。坚定的 FAM19A4 遗体的生物功能,和它的潜在的受体是 unclarified。在这研究,我们证明 FAM19A4 是古典能分泌的蛋白质,我们第一次证实它的成熟蛋白质由 95 氨基酸组成。我们发现这新奇 cytokine 的表示是 upregulated 在里面 lipopolysaccharide (LPS ) 刺激了单核白血球和巨噬细胞并且典型地在极化的 M1。FAM19A4 在巨噬细胞上显示出趋化性的活动并且随蛋白质 kinase B (Akt ) 的 phosphorylation 的显著增加在 vitro 并且在 vivo 提高 zymosan 的巨噬细胞吞噬作用。FAM19A4 能也在 zymosan 刺激之上增加反应的氧种类(ROS ) 的版本。基于受体成为主观,收音机 ligand 绑定试金和受体阻塞,而且,我们第一次证明 FAM19A4 是甲酰肽受体 1 的新奇 ligand (FPR1 ) 。上述数据显示在煽动性的刺激之上, monocyte/macrophage-derived FAM19A4 可以在病原的感染期间在巨噬细胞的移植和激活起一个关键作用。 | Wenyan Wang Ting Li Xiaolin Wang Wanxiong Yuan Yingying Cheng Heyu Zhang Enquan Xu Yingmei Zhang Shuang Shi Dalong Ma Wenling Han | 2015 | Cellular & Molecular Immunology2015，12，5： | 8 |
| 2 | Fine equiaxed β grains and superior tensile property in Ti-6Al-4V alloy deposited by coaxial electron beam wire feeding additive manufacturing显示文摘Coarse columnar β grains result in anisotropic mechanical properties in Ti alloys deposited by additive manufacturing. This study reports that Ti-6Al-4V alloy fabricated by coaxial electron beam wire feeding additive manufacturing presents a weak anisotropy, high strength and ductility. The superior tensile property arises from a microstructure with fine equiaxed β grains(EGβ), discontinuous grain boundary α phase and short intragranular α lamellae. A large region of fine EGβ arises from a special combination of the temperature gradient and solidification rate, and attractive α morphology is caused by solid phase transformations during interpass thermal cycling and post heat treatments. | Jiahua Zhang Yi Yang Sheng Cao Zhiqiang Cao Dmytro Kovalchuk Songquan Wu Enquan Liang Xi Zhang Wei Chen Fan Wu Aijun Huang | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，10： | 5 |
| 3 | Behavior and adrenal activity in a group of zoo golden snub-nosed monkeys,Rhinopithecus roxellana,following social structure change显示文摘The effects of individual removal by zoo managers on behavior and fecal glucocorticoid changes in snub-nosed monkeys(Rhinopithecus roxellana) were investigated at Beijing Zoo.The results showed that the effect of the removal of three subordinate individuals(DD,male,4 years;XZZ,male,3 years and LL,female,3 years) from a group varied across the remaining group members that may be related to individual's social status,gender and age.The dominant male was impacted less than subordinate individuals in both the frequency and time duration for the four main behavioral categories.The frequency of stereotypic behavior significantly decreased in the dominant female after the removal of three animals(Z= 2.862,P=0.003).Fluctuations were found in both the behavioral frequency and time duration in other remaining individuals.These findings suggest that small,socially stable groups were somewhat resilient to changes in member composition.Moreover,the cortisol level did not change significantly in the remaining members.An alternative method of hormone assay using fecal samples for vulnerable animals was presented,and that may be useful for monitoring wild golden monkeys and other endangered species of animal. | ZHANG XiaoLii HE Xini LIU DingZheni YAO XiuLini ZHANG YiZhuo ZHANG EnQuan ZHANG JinGuo JIANG GuoHua ZHAO ChangQi | 2013 | Chinese Science Bulletin2013，58，17： | 4 |
| 4 | Optimized design and experiment of a fully automated potted cotton seedling transplanting mechanism显示文摘In order to improve the accuracy and stability of transplanting machine seedling picking,a seedling pick-up mechanism was designed,which was controlled by a controller and driven by brushless DC servo motor.At the same time,the parameters of the seedling manipulator were optimized:the mathematical model for the seedling pick-up mechanism was established.According to the predetermined trajectory requirements,the objective function and constraint conditions were proposed,and then the optimal size was obtained by a multi-objective genetic algorithm.At last,Automatic Dynamic Analysis of Mechanical Systems(ADAMS)software was used to simulate and analyze the kinematics and trajectory of the seedling pick-up mechanism,and the mechanism was tested to verify the effectiveness of the mechanism prototype.The experiments showed that the success rate of seedling picking was 94.32%,the rate of acceptably planted seedlings was 96.67%,and the rate of excellently planted seedlings was 63.48%. | Xianglei Xue Lianhao Li Chunlin Xu Enquan Li Yujie Wang | 2020 | International Journal of Agricultural and Biological Engineering2020，13，4： | 3 |
| 5 | Effects of odors on behaviors of captive Amur leopards Panthera pardus orientalis显示文摘Captive environments often fail to resemble the wild environment in respects of limited space,unchanging habitat,lack of stimulus and contingency. Common animal welfare problems which occur in captive animals include low behavioral diversity,abnormal behavior and excessive inactivity. Environmental enrichment,as an effective strategy to tackle these problems and promote mental health of captive animals,has been recognized as an important principal for captive animal management. Among all the enrichment techniques,olfactory enrichment is a simple and effective method for improving the well-being of the olfactory sensitive felids. Behavioral problems were observed in six Amur leopards Panthera pardus orientalis at Beijing Zoological Garden. These were held in the older type exhibits which have now been rebuilt. These behaviors include stereotypic behavior and excessive inactivity caused by the spatially limited enclosures with low levels of stimuli. To determine the effects of predator,prey,and herb odors as potential enrichment materials for captive leopards,we conducted olfactory enrichment experiments for the leopards and tested the effects of nutmeg Myristica fragrans,feces of roe deer Capreolus capreolus and urine of Amur tiger Panthera tigris altaica to test for an increase in behavioral repertoire and activity. Odors provided in this study were also believed to improve the psychological and physiological health of individuals. To standardize the method of presentation the odors were introduced to the enclosures by rubbing or spraying onto a clean towel. Our results show that the selected three odors effectively increased the behavioral diversity. Ten new behavior types were observed in the nutmeg experiment,eight in the feces of roe deer experiment and six in the tiger urine experiment. Among the three odors,cats responded to nutmeg for the longest duration,followed by tiger urine and feces of roe deer. Leopards showed more play behavior in presence of nutmeg while more investigatory behavior in presences of feces of roe deer and tiger urine. Providing novel odors increased the spatial use of the exhibit and the animal's increased use of the logs,sleeping platforms and bars in the cages. Novel odors also significantly increased the overall activity of the leopards,but the effects were diminished in about three | Shuangying YU Zhigang JIANG Hui ZHU Chunwang LI Enquan ZHANG Jinguo ZHANG Carin HARRINGTON | 2009 | Current Zoology2009，55，1： | 2 |
| 6 | Synthesis of single phase β-SiAlON ceramics by reaction-bonded sintering using Si and Al2O3 as raw materials显示文摘 | He Enquan Yue Jianshe Fan Lei | 2011 | Scripta Mater2011，65，2： | 1 |
| 7 | Synthesis of single phase β-SiAlON ceramics by reaction-bonded sintering using Si and Al 2 O 3 as raw materials显示文摘 | Enquan He Jianshe Yue Lei Fan Chao Wang Hongjie Wang | 2011 | Scripta Materialia2011，，2： | 1 |
| 8 | Synthesis of single phase B-SiAION ceramics by reaction-bonded sintering using Si and AI~O3 as raw materials显示文摘 | He Enquan Yue Jianshe Fan Lei | 2011 | Scripta Materialia2011，65，2： | 1 |
| 9 | Application of Continuous Scanning Method in Phase-measuring of Underwater Acoustic Signals 显示文摘 | Guo Enquan | 2002 | NIWEEK97 Proceeding2002，2002，： | 1 |
| 10 | Synthesis of single phaseβ-SiAlON ceramics by reaction-bonded sintering using Si and Al2O3asraw materials显示文摘 | HE Enquan YUE Jianshe Fan Lei | 2011 | Scri Mater2011，65，15： | 1 |
| 11 | Characterization of the sphingolipid profiling of Emiliania huxleyi against virus infection显示文摘Lipidomics approach by UPLC-Q-Exactive-MS was used for the identification,quantification,comparison,and characterization of sphingolipids in virus infected marine Emiliania huxleyi BOF92 cells.The results show that 16 significantly changed sphingolipids(including Cer,CerG1,and SPHm)were identified during viral infection.Our data confirmed previously recognized facts that viral infection led to a shift toward virus-specific sphingolipids,which is consistent with the down-regulation of genes involved in the host de novo sphingolipid biosynthesis.Moreover,we revealed the upregulation of virusencoded homologous genes participating in de novo sphingolipids biosynthesis and virus-specific hydroxylated long chain bases(LCBs)as phytoCer,suggesting the competitive inhibition of host sphingolipid synthesis to produce the required building blocks for viral production,replication,and assembly.Additionally,Cer 40꞉1;2,Cer 40꞉2;2 isomer,and CerG139꞉0;2,Cer 39꞉0;2 as novel metabolite markers might indicate the general dysfunctions in E.huxleyi in response to viral infection.Our results show that viral infection led to a profound remodeling of host sphingolipidome,by which viruses depend on the hijacking of host sphingolipid metabolism to support the viral life cycle. | Jingwen LIU Jingjing GAO Enquan ZHANG Hanrui JIANG Guiling LI Jian LI Jun ZENG Daren WU | 2023 | Journal of Oceanology and Limnology2023，41，4： | 0 |
| 12 | Seismic stability of expansive soil slopes reinforced by anchor cables using a modified horizontal slice method显示文摘Earthquake-induced slope failures are common occurrences in engineering practice and pre-stressed anchor cables are an effective technique in maintaining slope stability,especially in areas that are prone to earthquakes.Furthermore,the soil at typical engineering sites also exhibit unsaturated features.Explicit considerations of these factors in slope stability estimations are crucial in producing accurate results.In this study,the seismic responses of expansive soil slopes stabilized by anchor cables is studied in the realm of kinematic limit analysis.A modified horizontal slice method is proposed to semi-analytically formulate the energy balance equation.An illustrative slope is studied to demonstrate the influences of suction,seismic excitations and anchor cables on the slope stability.The results indicate that the stabilizing effect of soil suction relates strongly to the seismic excitation and presents a sine shape as the seismic wave propagates.In higher and steeper slopes,the stabilizing effect of suction is more evident.The critical slip surface tends to be much more shallow as the seismic wave approaches the peak and vice versa. | Wang Long Chen Guoxing Hu Wei Zhou Enquan Feng Jianxue Huang Anping | 2024 | Earthquake Engineering and Engineering Vibration2024，23，2： | 0 |
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