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59篇 您的检索式:作者名="Esplugues"
    题名 作者 年代 出处 被引量
1Education-based approach to addressing non-evidence-based practice in preventing NSAID-associated gastrointestinal complications显示文摘AIM:To evaluate an evidence-based educational program for improving strategies for prevention of non-steroidal anti-inflammatory drug(NSAID)-associated gastrointestinal(GI)complications. METHODS:Four hundred and fifty-six specialists replied to a questionnaire that covered issues related to NSAID-induced adverse effects.They also collected data from their last five consecutive patients before and after they had attended an evidence-based seminar on GI prevention strategies. RESULTS:Four hundred and forty-one of 456 specialists(96.7%)participated in the survey,and 382(83.7%)in the education-based study that recorded data from 3728 patients.The specialists overestimated the risk of GI complications with NSAIDs,underestimated the GI safety profile of coxibs,but were aware of the risk factors and of the current prevention strategies.Proton pump inhibitors were co-prescribed with NSAIDs in>80% of patients with and without risk factors.The educational program had little impact on prescribing habits.CONCLUSION:Specialists are informed of advances in NSAID-associated adverse effects and have high rates of GI-prevention therapy.Our educational program did not alter these rates.Angel Lanas Juan V Esplugues Javier Zapardiel Eduardo Sobreviela 2009World Journal of Gastroenterology2009,15,47:5
2Thl7 cells express interleukin-10 receptor and are controlled by Foxp3- and Foxp3* regulatory D T cells in an interleukin-10 dependent manner显示文摘Huber S Gagliani N Esplugues E 2011Immunity2011,34,4:1
3Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells显示文摘Lark Kyun Kim Enric Esplugues Cornelia E. Zorca Niels J. Galjart Richard A. Flavell 2014Molecular Cell2014,,:1
4Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ in- hibition显示文摘Apostolova N Blas-Garcia A Esplugues J V 2011Trends Pharmacol Sci2011,32,12:1
5Thl7c-ells express interleukin-10 receptor and are controlled byFoxp3- and Foxp3+ regulatory CD4+ Tcells in an inter-leukin-10 -dependent manner 显示文摘HUBER S GAGLIANIN ESPLUGUES E 2011Immunity2011,34,4:1
6Thl7 cells ex- press interleukin-10 receptor and are continUed by Foxp3 - and Foxp3 + regulatory CIM + T cells in an interleukin-10-dependent manner 显示文摘Huber S Gagliani N Esplugues E 2011Immunity2011,34,4:1
7Complex 1 dysfunction and tolerance to nitroglycerin an approach based on mitochondrialtargeted antioxidants显示文摘Esplugues J V Rocha M Nunez C 2006Circ Res2006,99,10:1
8Role of free radicals in sepsis:antioxidant therapy显示文摘Victor VM Rocha M Esplugues JV 2005Curr Pharm Des2005,11,24:1
9Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases:perspective for drugs development显示文摘 Panes J and Esplugues JV 2001Curr Pharm Des2001,7,:1
10Role of free radicals in sepsis : antioxidant therapy 显示文摘Victor V M Rocha M Esplugues J V 2005Curr Pharm Des2005,11,24:1
11Twenty years of HIV-1 non-nucleoside reverse transcriptase inhibitors: time to ree valuate their toxicity显示文摘Esplugues J V Blas-Garcia A and Apostolova N 2011Curr Med Chem2011,18,10:1
12Thl7 cells ex-press interleukin - 10 receptor and are controlled by Foxp3 and Foxp3+ regulatory CD4 + T cells in an interleukin - 10 dependent manne显示文摘Samuel Huber Nicola Gagliani Enric Esplugues 2011Immunity2011,2234,4:1
13Th17 cells express inter- leukin-lO receptor and are controlled by Foxp3 (-) and Foxp3+ regulatory CD4 + T cells in an interleukin- 10- dependent manner 显示文摘Huber S Gagliani N Esplugues E 2011Immunity2011,34,4:1
14Enhanced antitumor immunity in mice deficient in CD69 显示文摘Esplugues E Sancho D Vega- Ramos J 2003J Exp Med2003,197,9:1
15MitochondnaI toxicity m HAART: an overview of in vitro evidence显示文摘Apostolova N Blas-Garcia A Esplugues JV 2011Curt Pharm Des2011,17,20:1
16The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation 显示文摘Pique J E Whittle B J R Esplugues J V 1989Eur J Pharmacol1989,174,:1
17Control of TH17 cells occurs in the small intestine显示文摘Esplugues E Huber S Gagliani N 2011Nature2011,475,7357:1
18Role of nitric oxide in gastrointestinal inflammatory and ulcerative diseases: perspective for drugs development 显示文摘Barrachina M D Panes J Esplugues J V 2001Curt Pharm Des2001,7,1:1
19NO as a signaling molecule in the nervous sys- tem 显示文摘Esplugues JV 2002Br J Pharmacol2002,135,5:1
20NO as a signalling molecule in the nervous system显示文摘Esplugues J V 2002Br J Pharamcol2002,135,5:1
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