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| 1 | Predictive findings forHelicobacter pylori-uninfected, -infected and -eradicated gastric mucosa: Validation study显示文摘AIM:To validate the usefulness of screening endoscopy findings for predictingHelicobacter pylori (H. pylori) infection status. METHODS:H. pylori infection status was determined by histology, serology, and the urea breast test in 77 consecutive patients who underwent upper endoscopy. Based on the findings, patients were categorized as H. pylori -uninfected, -infected, or -eradicated cases. Using six photos of certain sites in the stomach per case, we determined the presence or absence of the following endoscopic findings:regular arrangement of collecting venules (RAC), linear erythema, hemorrhage, fundic gland polyp (FGP), atrophic change, rugal hyperplasia, edema, spotty erythema, exudate, xanthoma, and mottled patchy erythema (MPE). The diagnostic odds ratio (DOR) and inter-observer agreement (Kappa value) for these 11 endoscopic findings used in the determination of H. pylori infection status were calculated. RESULTS:Of the 77 patients [32 men and 45 women; mean age (SD), 39.7 (13.4) years] assessed, 28 were H. pylori uninfected, 28 were infected, and 21 were eradicated. DOR values were significantly high (< 0.05) for the following H. pylori cases:uninfected cases with RAC (11.5), linear erythema (24.5), hemorrhage (4.1), and FGP (34.5); for infected cases with atrophic change (8.67), rugal hyperplasia (15.8), edema (14.2), spotty erythema (11.5), and exudate (3.52); and for eradicated cases with atrophic change (32.4) and MPE (103.0). Kappa values were excellent for FGP (0.93), good for RAC (0.63), hemorrhage (0.79), atrophic change (0.74), and MPE (0.75), moderate for linear erythema (0.51), rugal hyperplasia (0.49), edema (0.58), spotty erythema (0.47), and exudate (0.46), and poor for xanthoma (0.19). CONCLUSION:The endoscopic findings of RAC, hemorrhage, FGP, atrophic change, and MPE will be useful for predicting H. pylori infection status. | Kazuhiro Watanabe Naoyoshi Nagata Ryo Nakashima Etsuko Furuhata Takuro Shimbo Masao Kobayakawa Toshiyuki Sakurai Koh Imbe Ryota Niikura Chizu Yokoi Junichi Akiyama Naomi Uemura | 2013 | World Journal of Gastroenterology2013，19，27： | 17 |
| 2 | A High-Precision US-Guided Robot-Assisted HIFU Treatment System for Breast Cancer显示文摘乳腺癌是女性中最常见的癌症。高强度聚焦超声(波)(HIFU)是一种很有前景的非介入式治疗方法。为了提高HIFU治疗的精确度和降低治疗成本,开发了一套基于超声引导(US)的五自由度辅助HIFU系统。搭建了一套功能齐全的样机,它可以轻松地实现三维超声图像重建、目标分割、治疗路径生成和HIFU自动照射等功能。利用线模型实现点定位,并且在异构组织模型上对凝固区域进行评估。在超声引导下,HIFU治疗区域的中心偏离目标治疗区域中心不到2 mm。规划治疗区域周围出现的超调值远低于在临床使用的允许值。对于乳腺癌的治疗,本系统有足够的准确性。 | Tianhan Tang Takashi Azuma Toshihide Iwahashi Hideki Takeuchi Etsuko Kobayashi Ichiro Sakuma | 2018 | Engineering2018，4，5： | 3 |
| 3 | Berth allocation in a container port: using a continuous location space approach显示文摘 | Akio Imai Xin Sun Etsuko Nishimura Stratos Papadimitriou | 2004 | Transportation Research Part B2004，，3： | 3 |
| 4 | Surgical resection of a solitary para-aortic lymph node metastasis from hepatocellular carcinoma显示文摘Lymph node (LN) metastases from hepatocellular carcinoma (HCC) are considered uncommon. We describe the surgical resection of a solitary para-aortic LN metastasis from HCC. A 65-year-old Japanese man with B-type liver cirrhosis was admitted for the evaluation of a liver tumor. He had already undergone radiofrequency ablation, transcatheter arterial chemoembolization, and percutaneous ethanol injection therapy for HCC. Despite treatment, viable regions remained in segments 4 and 8. We performed a right paramedian sectionectomy with partial resection of the left paramedian section of the liver. Six months later, serum concentrations of alpha-fetoprotein (189 ng/mL) and PIVKA-2 (507 mAU/mL) increased. Enhanced com- puted tomography of the abdomen revealed a tumor (20 mm in diameter) on the right side of the abdominal aorta. Fluorine-18 fluorodeoxyglucose positron emission tomography revealed an increased standard uptake value. There was no evidence of recurrence in other regions. Esophagogastroduodenoscopy and colonoscopy revealed no malignant tumor in the gastrointestinal tract. Para-aortic LN metastasis from HCC was thus diagnosed. We performed lymphadenectomy. Histopathological examination revealed that the tumor was largely necrotic, with poorly differentiated HCC on its surface, which confirmed the suspected diagnosis. After 6 mo tumor marker levels were normal, with no evidence of recurrence. Our experience suggests that a solitary para-aortic LN metastasis from HCC can be treated surgically. | Junji Ueda Hiroshi Yoshida Yasuhiro Mamada Nobuhiko Taniai Sho Mineta Masato Yoshioka Youichi Kawano Tetsuya Shimizu Etsuko Hara Chiaki Kawamoto Keiko Kaneko Eiji Uchida | 2012 | World Journal of Gastroenterology2012，18，23： | 3 |
| 5 | Hepatocellular carcinoma in patients with nonalcoholic steatohepatitis显示文摘 | Etsuko Hashimoto Satoru Yatsuji Maki Tobari Makiko Taniai Nobuyuki Torii Katsutoshi Tokushige Keiko Shiratori | 2009 | Journal of Gastroenterology2009，，19： | 3 |
| 6 | 巨噬细胞集落刺激因子对破骨细胞生物作用的实验研究显示文摘目的 探讨在实验条件下巨噬细胞集落刺激因子 (M CSF)在骨代谢过程中对破骨细胞的生物作用。方法 用不同浓度的M CSF和活化核因子κB的受体配体 (RANKL)与鼠骨髓细胞培养 ,在加入或不加入牛骨片的情况下诱导产生破骨细胞。分别用抗酒石酸酸性磷酸酶 (TRAP)染色法和骨小坑染色法检测TRAP阳性的破骨细胞量及破骨细胞功能。结果 在一定范围内 ,M CSF在RANKL存在的条件下诱导TRAP阳性破骨细胞成熟 ,并随M CSF剂量的增加TRAP阳性细胞数明显增加 (r =0 .75 0 4,P <0 .0 1) ;且骨小坑数量也与M CSF剂量呈明显正相关 (r=0 .93 65 ,P≤ 0 .0 0 0 1)。缺乏M CSF或RANKL均不能诱导TRAP阳性的破骨细胞产生 (P =0 .0 191)。结论 破骨细胞的增殖、分化及成熟是由M CSF和RANKL共同调节的。M CSF是破骨细胞代谢过程中的关键因子 ,具有促进破骨细胞对骨吸收的作用。M CSF对骨代谢的主要作用之一是上调破骨系统。 | 吴学宾 Abe Etsuko | 2004 | 现代医学2004，32，3： | 3 |
| 7 | Activation of Trifluoromethylthio Moiety by Appending Iodonium Ylide under Copper Catalysis for Electrophilic Trifluoromethylation Reaction显示文摘A 小说 iodonium-ylide 化合物 2 那添加 atrifluoromethylthio (SCF 3) 组是被揭示一新,架马厩 electrophilic trifluoromethylation 试剂。不同于已知的架马厩 electrophilic trifluoromethylation 试剂, 2 让稳定的 SCF 3 组织哪个被经由 sulfonium ylide 在铜催化作用下面添加 iodonium ylide 产生 cationic trifluoromethyl 激活(CF 3) 种类。试剂 2 被发现是为大量 silyl enol 醚的有效 electrophilic trifluoromethylation 试剂 3 在铜下面催化作用。周期、非循环的 α-trifluoromethyl 酉同类 4 被在的试剂 2 获得对好收益中等。在另一方面, 5 没影响的 difluoromethylthio 类似物分子间的转移 difluoromethylation 到底层。相反, intramolecular 1,4 迁居继续了类似于 Stevens 重新整理到在 21% 产量提供 6,独立于 nucleophiles 的存在 3。 | Ibrayim Saidalimu Shugo Suzuki Etsuko Tokunaga Norio Shibata | 2016 | Chinese Journal of Chemistry2016，34，5： | 3 |
| 8 | Hepatocarcinogenesis in non‐alcoholic fatty liver disease in J apan显示文摘 | Katsutoshi Tokushige Etsuko Hashimoto Kazuhiko Kodama | 2013 | J Gastroenterol Hepatol2013，，： | 2 |
| 9 | Prospective study of hepatocellular carcinoma in nonalcoholic steatohepatitis in comparison with hepatocellular carcinoma caused by chronic hepatitis C显示文摘 | Katsutoshi Tokushige Etsuko Hashimoto Satoru Yatsuji Maki Tobari Makiko Taniai Nobuyuki Torii Keiko Shiratori | 2010 | Journal of Gastroenterology2010，，9： | 2 |
| 10 | Decitabine—Bedside to bench显示文摘 | Yasuhiro Oki Etsuko Aoki Jean-Pierre J. Issa | 2006 | Critical Reviews in Oncology and Hematology2006，，2： | 2 |
| 11 | Characteristics of Patients With Nonalcoholic Steatohepatitis Who Develop Hepatocellular Carcinoma显示文摘 | Kohichiroh Yasui Etsuko Hashimoto Yasuji Komorizono Kazuhiko Koike Shigeki Arii Yasuharu Imai Toshihide Shima Yoshihiro Kanbara Toshiji Saibara Takahiro Mori Sumio Kawata Hirofumi Uto Shiro Takami Yoshio Sumida Toshinari Takamura Miwa Kawanaka Takeshi Oka | 2011 | Clinical Gastroenterology and Hepatology2011，，5： | 2 |
| 12 | Hepatocellular carcinoma in patients with nonalcoholic steatohepatitis显示文摘 | Etsuko Hashimoto Satoru Yatsuji Maki Tobari Makiko Taniai Nobuyuki Torii Katsutoshi Tokushige Keiko Shiratori | 2009 | Journal of Gastroenterology2009，，19： | 2 |
| 13 | Berth Allocation at Indented Berths for Megacontainerships显示文摘 | Akio Imai Etsuko Nishimura Masahiro Hattori | 2007 | European Journal of Operational Research2007，，179： | 1 |
| 14 | Posteroanterior cephalometric study of cranio- facial and arch width显示文摘 | Etsuko K Kosuke M | 1972 | J Jap Orhtodntic Society1972，31，2： | 1 |
| 15 | Ryegrass enhancement of biodegradation in diesel-contaminated soil显示文摘 | ETSUKO K TSUKASA M SHYOJI M | | Environmental and Experimental Botany0，55，： | 1 |
| 16 | The dynamic berth allocation problem for a container port 显示文摘 | Aikio Imai Etsuko Nishimura Stratos Papadimitriou | 2001 | Transportation Re- search Part B: Methodological2001，35，4： | 1 |
| 17 | Nitric oxide production by superficial and deep articular chondrocytes 显示文摘 | Takeshi H Etsuko A Tomoo Y | 1997 | Arthritis Rheum1997，，： | 1 |
| 18 | Berth allocation with service priority显示文摘 | Akio Imai Etsuko Nishimura Stratos Papadimitriou | 2003 | Transportation Research Part B: Methodologi- cal2003，37，5： | 1 |
| 19 | Effect of ultra- sonic irradiation on the behavior of primary nucleation of amino acids in supersaturated solutions 显示文摘 | Masahiro K Etsuko M Satomi E | 2009 | Journal of Crystal Growth2009，311，9： | 1 |
| 20 | The dynamic berth allocation problem for a container port显示文摘 | Akio Imai Etsuko Nishimura Stratos Papadimitriou | 2001 | Transpor- tation Research Part E2001，，35： | 1 |
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