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| 1 | In vivo evaluation of urokinase-loaded hollow nanogels for sonothrombolysis on suture embolization-induced acute ischemic stroke rat model显示文摘The urokinase-type plasminogen activator(uPA)loaded hollow nanogels(nUK)were synthesized by a one-step reaction of glycol chitosan and aldehyde capped poly(ethylene oxide).The resultant formulation is sensitive to diagnostic ultrasound(US)of 2 MHz.Herein,we evaluated the in vivo sonothrombolysis performance of the nUK on acute ischemic stroke rat model which was established by suture embolization of middle cerebral artery(MCA).Via intravenous(i.v.)administration,the experimental data prove a controlled release of the therapeutic protein around the clots under ultrasound stimulation,leading to enhanced thrombolysis efficiency of the nUK,evidenced from smaller infarct volume and better clinical scores when compared to the i.v.dose of free uPA no matter with or without US intervention.Meanwhile,the preservation ability of the nanogels not only prolonged the circulation duration of the protein,but also resulted in the better blood-brain barrier protection of the nUK formulation,showing no increased risk on the hemorrhagic transformation than the controls.This work suggests that the nUK is a safe sonothrombolytic formulation for the treatment of acute ischemic stroke. | Yuming Teng Haiqiang Jin Ding Nan Mengnan Li Chenghe Fan Yuanyuan Liu Pu Lv Wei Cui Yongan Sun Hongjun Hao Xiaozhong Qu Zhenzhong Yang Yining Huang | 2018 | Bioactive Materials2018,3,1: | 7 |
| 2 | Catalytic dehydrogenation of propane to propylene over highly active PtSnNa/γ-Al2O3 catalyst显示文摘PtSnNa/γ-Al_2 O_3 catalyst is widely used in the dehydrogenation of light alkane. This paper reports a new fabrication method of the catalyst. In the work, γ-Al_2 O_3, SnCl_4 and NaCl were ball milled to upload Sn and Na^+ onto the support instead of the conventionally used immersion method. The subsequent baking procedures frimly fixed Sn onto the support, which could disperse Pt introduced by immersion. The effects of Sn and Na^+ additives on the catalytic performance of PtSnNa/γ-Al_2 O_3 catalyst were investigated. It was found that the appropriate molar ratio of Sn/Pt was 6:1 while the favorable weight percentage of Na^+was 0.90%. Compared with the reaction catalyzed by the industrially employed PtSnNa/γ-Al_2 O_3 catalyst, the conversion of propane and the selectivity of propylene had been greatly improved,which were 26.97% and 99.18% respectively after 12 h reaction. | Shiyong Zhao Bolian Xu Lei YU Yining Fan | 2018 | Chinese Chemical Letters2018,29,3: | 4 |
| 3 | Honeycomb-shaped Pt Sn Na/y-Al2O3/cordierite monolithic catalyst with improved stability and selectivity for propane dehydrogenation显示文摘novel honeycomb-shaped Pt Sn Na/g-Al_2 O_3/cordierite monolithic catalyst(Pt 0.5%, Sn 0.9%, Na 1.0%,relative to Al2 O3 weight) was developed and its catalytic performances in propane dehydrogenation were tested and compared with the classical granule catalyst with same Pt, Sn and Na contents under the conditions of 0.1 MPa, 590C, C_3 H_8/H_2 at 3/1(molar ratio) and gas hourly space velocity(GHSV) at155 h^(-1). Interestingly, despite the generated coke amount and exposed Pt fraction, the honey combshaped structure of monolithic catalyst exerted important influences on its catalytic activities and led to the advanced catalytic performances over the granule catalyst. | Shiyong Zhao Bolian Xu Lei Yu Yining Fan | 2018 | Chinese Chemical Letters2018,29,6: | 2 |
| 4 | Factors influencing Li^(+)migration in garnet-type ceramic electrolytes显示文摘Garnet-type ceramic electrolyte with exceptionally high Li^(+) conductivity has attracted wide interests for the development of safe electrochemical devices.However,the factors affecting the ionic migration still deserve more attentions.In this study,five garnet-types ceramic electrolyte were chosen to investigate the factors.The thermal behavior of garnet-type electrolyte during sintering was studied to achieve high conductivity.The electrochemical properties are correlated with crystal structure,migrating route and lattice parameters.Nine influening factors were discussed to analyze the ionic migration in garnet-type ceramic electrolyte. | Yu Huan Yi Fan Yining Li Baoyi Yin Xun Hu Dehua Dong Tao Wei | 2019 | Journal of Materiomics2019,5,2: | 2 |
| 5 | Pore diffusion simulation model of bi modal catalyst for Fischer-Tropsch synthesis 显示文摘 | Xu Bolian Fan Yining | 2005 | AIChE Journal2005,51,7: | 1 |
| 6 | A novel method for preparation of nanocrystalline mtile TiO2 powders by liquid hydrolysis of TiCl4显示文摘 | LI Yuanzhi FAN Yining CHEN Yi | 2002 | J Mater Chem2002,12,: | 1 |
| 7 | The effect of titania polymorph on the strong metal-support interaction of Pd/TiO2 catalysts and their application in the liquid phase selective hydrogenation of long chain alkadienes显示文摘 | Li Yuanzhi Xu Bolian Fan Yining | 2004 | J Mol Catal A:Chem2004,216,: | 1 |
| 8 | Structure and reactivity of ultrafine CE-MO oxide particles显示文摘 | WENXING KUANG YINING FAN YI CHEN | 2001 | Catalysis Today2001,68,: | 1 |
| 9 | Partial oxidation of toluene over ultrafine mixed Mo-based oxide particles 显示文摘 | Kuang Wenxing Fan Yining Chen Kaidong | 1999 | Journal of Catalysis1999,186,2: | 1 |
| 10 | Selective liquid hydrogenation of long chain linear alkadienes on molybdenum nitride and carbide modified by oxygen显示文摘 | LI Yuanzhi FAN Yining HE Jie | 2004 | Chem Eng J2004,99,3: | 1 |
| 11 | Preparation and characterization of ultrafine rare earth molybdenum complex oxide particles显示文摘 | KUANG Wenxing FAN Yining YAO Kaiwen | 1998 | Journal of Solid State Chemistry1998,140,2: | 1 |
| 12 | A novel method for preparation of nanocrystalline futile TiO2 powders by liquid hydrolysis of TiCl4显示文摘 | Yuanzhi Li Yining Fan Yi Chen | 2002 | J Mater Chem2002,,12: | 1 |
| 13 | Propane dehydrogenation over the PtSn catalyst supported on alumina-modified SBA-15显示文摘 | Lihua Huang Bolian Xu Lili Yang Yining Fan | 2008 | Catalysis Communications2008,,15: | 1 |
| 14 | Cilostazol as an alternative to aspirin after ischaemic stroke: a randomised, double-blind, pilot study显示文摘 | Yining Huang Yan Cheng Jiang Wu Yansheng Li En Xu Zhen Hong Zhengyi Li Weiwei Zhang Meiping Ding Xuguang Gao Dongsheng Fan Jinsheng Zeng Kasing Wong Chuanzhen Lu Jiangxi Xiao Chen Yao | 2008 | Lancet Neurology2008,,6: | 1 |
| 15 | Thermostable Nitrogen-Doped HTiNbO5 Nanosheets with a High Visible-Light Photocatalytic Activity显示文摘做氮的 HTiNbO5 nanosheets 被第一 exfoliating 成功地综合了在 tetrabutylammonium 氢氧化物(TBAOH ) 到的分层的 HTiNbO5 获得 HTiNbO5 nanosheets 然后与脲加热 nanosheets。产生样品被 X 光检查描绘衍射(XRD ) ,传播电子显微镜学(TEM ) ,扫描电子显微镜学(SEM ) ,精力散的 X 光检查(EDX ) , X 光检查光电子光谱学(XPS ) ,紫外力的光谱学和 N2 吸附解吸附作用大小。在分层的结构,内在的 bandgap 变窄和可见轻回答的高得多的 thermostability 结果,被发现那做 N。做的氮原子主要位于 TiNbO5 lamellae 的空隙的地点并且化学上跳了到氢离子。与做 N 的 HTiNbO5 相比,做 N 的 HTiNbO5 nanosheets 由于 titanoniobate nanosheets 的相当松开、不规则的安排有一个大得多的特定的表面区域和更富有的 mesoporosity。做 N 的分层的 HTiNbO5 和 HTiNbO5 nanosheets 为玫瑰精 B (RhB ) 的降级显示出一项很高可见光的 photocatalytic 活动水的答案。而且由于更加更大的表面区域,更富有的 mesoporosity 和更强壮的酸味,做 N 的 HTiNbO5 nanosheets 比做 N 的 HTiNbO5 举办了一项甚至更高的活动,尽管后者在可见区域有更强壮的吸收。染料分子主要被降级到脂肪族的有机化合物并且部分使矿物化到 CO2 或公司,而非简单地被将脱色。photosensitization 的效果是不足道的, RhB 主要经由典型 photocatalytic 反应线路被降级。为在在做 N 的 HTiNbO5 nanosheets 上的可见轻照耀下面的 RhB 的 photodegradation 的二条不同反应线路被建议了。现在的方法能被扩大到有置闰和脱落的特征的很多分层的金属氧化物,因此为高度有效、潜在地实际的可见光的光催化剂的制造提供新机会。 | Zheng Zhai Yucheng Huang Lin Xu Xiaoyan Yang Chenhui Hu Lihong Zhang Yining Fan Wenhua Hou | 2011 | Nano Research2011,4,7: | 1 |
| 16 | Surface Structure and Catalyric Performance of Supported PtSn Catalysts 显示文摘 | Yang Weisheng Lin Liwu Fan Yining | 1992 | Catal Lett1992,12,13: | 1 |
| 17 | Study on the Reduction Behavior of Zirconia Supported Iron Oxide Catalysts by Temperature-programmed Reduction Combined with in Situ Moessbauer Spectroscopy显示文摘 | CHEN Kaidong FAN Yining HU Zheng | 1996 | Journal of Solid State Chemistry (S0022-4596)1996,121,1: | 1 |
| 18 | Preparation and Characterization of Ultrafine Rare Earth Molybdenum Complex Oxide Particles 显示文摘 | Kuang Wenxing Fan Yining Yao Kaiwen | 1998 | Joumal of solid state chemistry1998,140,: | 1 |
| 19 | Cilostazol as an alternative to aspirin after ischaemic stroke: a randomised, double-blind, pilot study显示文摘 | Yining Huang Yan Cheng Jiang Wu Yansheng Li En Xu Zhen Hong Zhengyi Li Weiwei Zhang Meiping Ding Xuguang Gao Dongsheng Fan Jinsheng Zeng Kasing Wong Chuanzhen Lu Jiangxi Xiao Chen Yao | 2008 | Lancet Neurology2008,,6: | 1 |
| 20 | Partial oxidation of toluene over ultrafine mixed Mo-based oxide particles显示文摘 | Kuang Wenxing Fan Yining Chen Kaidong | 1999 | Journal of Catalysis1999,186,2: | 1 |