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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Developments in on-line,electron-beam emittence measurements using optical-transition radiation techniques显示文摘 | Feldman R B Lumpkin A H | 1990 | Nuclear Instruments and Methods in Physics Research1990，296，： | 2 |
| 3 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 4 | The design and fabrication of a 40 cm diameter,SiC coated,normal incidence telescope and spectrometer显示文摘 | Stephan R McCandliss Mel E Martinez Paul D Feldman | 1994 | SPIE1994，2011，： | 1 |
| 5 | Comparism between optical and electrical interconnects based on power and speedconsiderations 显示文摘 | | 1992 | ApplOpt1992，31，2： | 1 |
| 6 | New reactor for production of tungsten disulfide hollow onion-like (inorganic fullerene-like) nanoparticles显示文摘 | Zak A Popovita-Biro R | 2000 | Solid State Sci2000，2，： | 1 |
| 7 | A 50% reduction in the Psoriasis Area and Severity Index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis显示文摘 | Carlin C S Feldman S R Krueger J G | 2004 | J Am Acad Dermatol2004，50，6： | 1 |
| 8 | Investigation of the rapid chloride permeability test显示文摘 | FELDMAN R F CHAN G W BROUSSEAU R J | 1994 | ACI Materials Journal1994，91，3： | 1 |
| 9 | Alefacept treatment for chronic plaquepsoriasis显示文摘 | DunnL K Feldman S R | 2010 | Skin Therapy Lett2010，15，4： | 1 |
| 10 | Solar wind electrons 显示文摘 | FELDMAN W C ASBRIDGE J R BAME S J | 1975 | J Geophys Res1975，80，： | 1 |
| 11 | Retinoic acid signaling restricts the cardiac progenitor pool 显示文摘 | KEEGAN B R FELDMAN J L BEGEMANN G | 2005 | Science2005，307，5707： | 1 |
| 12 | Hydride generation activity of arsenosugars and thioarsenicals显示文摘 | REGMI R MILNE B F FELDMAN J | 2007 | Anal Bioanal Chem2007，388，： | 1 |
| 13 | Concrete Science显示文摘 | V S Ramachandran R F Feldman J J Beaudoin | 1981 | Hayden & Son Ltd1981，，： | 1 |
| 14 | Managing rosacea:a review of the use of metronidazole alone and in combination with oral antibiotics显示文摘 | Conde JF Yelveton CB Balkrishnan R Fleischer AB Jr Feldman SR | 2007 | 6:495-4982007，6，： | 1 |
| 15 | Parent - infant synehrony and the social - emotional development of triplets显示文摘 | Feldman R Eidelman AI | 2004 | Dev Psycho2004，40，6： | 1 |
| 16 | The Ex-ante assess- ment of knowledge spillovers: government R&D policy, economic incentives and private firm behavior显示文摘 | FELDMAN M P KELLEY M R | 2006 | Re- search Policy2006，35，10： | 1 |
| 17 | The giants among us显示文摘 | Ewing T Feldman R | | 0，，： | 1 |
| 18 | Hopeful choices: A school counselorg guide to hope theory显示文摘 | Snyder C R Feldman D Shorey H Rand K | 2002 | Journal of Personality2002，5，5： | 1 |
| 19 | High temperature, high pressure electrostatic precipitation显示文摘 | Bush J R Feldman P L Robinson M | 1979 | Journal of the Air Pollution Control Association1979，29，4： | 1 |
| 20 | A new estimate of the welfare loss of Excess health insurance 显示文摘 | Feldman R Dowd B | 1991 | The American Economic Review1991，81，1： | 1 |
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