维普期刊资源整合服务平台（V6.5）

73篇 您的检索式：作者名="FENG SJ"

选中清除导出查看参考文献查看引证文献引用追踪共4页首页上一页第1页下一页末页 /4 跳转

	题名	作者	年代	出处	被引量
1	LMP2-DC Vaccine Elicits Specific EBV-LMP2 Response to Effectively Improve Immunotherapy in Patients with Nasopharyngeal Cancer显示文摘Objective To evaluate the safety and effectiveness of a vaccine based on latent membrane protein 2(LMP2)modified dendritic cells(DCs)that boosts specific responses of cytotoxic T lymphocytes(CTLs)to LMP2 before and after intradermal injection in patients with nasopharyngeal carcinoma(NPC).Methods DCs were derived from peripheral blood monocytes of patients with NPC.We prepared LMP2-DCs infected by recombinant adenovirus vector expressing LMP2(rAd-LMP2).NPC patients were immunized with 2×105 LMP2-DCs by intradermal injection at week 0 and after the second and fourth weeks.Specific responses to LMP2 were detected by enzyme-linked immunospot(ELISPOT)assay at week 0 and at the fifth and eighth weeks.Local clinicians performed the follow-up and tracking of patients.Results We demonstrated that DCs derived from monocytes displayed typical DC morphologies;the expression of LMP2 in the LMP2-DCs vaccine was confirmed by immunocytochemical assay.Twenty-nine patients with NPC were enrolled in this clinical trial.The LMP2-DCs vaccine was well tolerated in all of the patients.Boosted responses to LMP2 peptide sub-pools were observed in 18 of the 29 patients with NPC.The follow-up data of 29 immunized patients from April,2010 to April 2015 indicated a five-year survival rate of 94.4%in responders and 45.5%in non-responders.Conclusion In this pilot study,we demonstrated that the LMP2-DCs vaccine is safe and effective in patients with NPC.Specific CTLs responses to LMP2 play a certain role in controlling and preventing the recurrence and metastasis of NPC,which warrants further clinical testing.	ZENG Yi SI Yong Feng LAN Gui Ping WANG Zhan ZHOU Ling TANG Min Zhong SJ O`Brien LAN Jiao ZHOU Xiang Yang WANG Yong Li TANG Juan ZHOU Zhi Xiang DU Hai Jun LIN Hui	2020	Biomedical and Environmental Sciences2020，33，11：	2
2	PEDF improves cardiac function in rats with acute myocardial infarction via inhibiting vascular permeability and cardiomyocyte apoptosis显示文摘	ZHANG H WANG Z FENG SJ et ol	2015	Int J Mol Sci2015，16，3：	1
3	Measuring fracture orientation at exposed rock faces by using a non-reflector total station显示文摘	FENG Q SJ(O)GREN P STEPHANSSON O	2001	Engineering Geology2001，59，12：	1
4	Dynamic properties of blood flow and leukocyte mobilization in infection flaps 显示文摘	Feng LJ Price DC Mathes SJ	1990	World J Surg1990，14，：	1
5	Cyclin degradation for cancer therapy and ehemoprevention 显示文摘	Freemantle SJ Liu X Feng Q	2007	Cell Biochem2007，102，4：	1
6	Cyclin degradation for cancer therapy and chemoprevention显示文摘	Freemantle SJ Liu X Feng Q	2007	Cell Biochem2007，102，4：	1
7	Short-wave near-infrared spectroscopy analysis of major compounds in milk powder and wavelength assignment显示文摘	Wu D He Y Feng SJ	2008	Anal Chim Acta2008，610，2：	1
8	On the Nevanlinna characteristic of f( z + TJ) and difference equations in the complex plane显示文摘	Chiang Y M Feng SJ	2008	The RamanujanJournal2008，16，：	1
9	Effects of APP 5-mer peptide analogue P165on the synaptic proteins and insulin signal transduction proteins显示文摘	Feng B Hu P Lu SJ	2014	Int J Clin Exp Med2014，7，3：	1
10	Complete withdrawal and subsequent allo~aft /'unction among pediatric recipi- ents of parental living donor liver transplants 显示文摘	Feng S Ekong UD Lobritto SJ	2012	JAMA2012，307，3：	1
11	Shotgun bisulphite se- quencing of the Arabidopsis genome reveals DNA methylation patterning显示文摘	COKUS SJ FENG S ZHANG X	2008	Nature2008，452，：	1
12	PEDF improves cardiac function in rats with acute myocardial infarction via inhibiting vascular permeability and cardiomyocyte apoptosis显示文摘	Zhang H Wang Z Feng SJ	2015	Interna- tional Journal of Molecular Sciences2015，16，5：	1
13	Outsourcing CO2 within China 显示文摘	FENG K SJ DAVIS X LI D GUAN L SUN Z LIU AND K HUBACEK	2013	Proceedings of the National Academy of Sciences2013，，110：	1
14	EPO-dependent activation of PI3K/Akt/FoxO3a signalling mediates neuroprotection in in vitro and in vivo models of Parkinson′s disease显示文摘	Jia Y Mo SJ Feng QQ	2014	J Mol Neurosci2014，53，1：	1
15	Generation of functional hemangioblasts from human embryonic stem ceils 显示文摘	Lu SJ Feng Q Caballero S	2007	Nat Methods2007，4，6：	1
16	64-slice CT perfusion imaging of pancreatic adenocarcinoma and mass-forming chronic pancreati- tis显示文摘	Lu N Feng XY Hao SJ	2011	Acad Radiol2011，18，1：	1
17	Identification and fine map- ping of AvrPil5, a novel avirulence gene of Magnaporthe grisea 显示文摘	Ma JkI Wang L Feng SJ	2006	Theoretical and Applied Genetics2006，113，5：	1
18	Cyclin degradation for cancer therapy and chemoprevention 显示文摘	Freemantle SJ Liu X Feng Q	2007	Cell Biochem2007，102，4：	1
19	The day when infection is confirmed is a better time point for mortality prediction in patients with severe acute pancreatitis显示文摘	Wang SQ Feng QX Li SJ	2012	Pancreas2012，41，4：	1
20	TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway 显示文摘	Tai YL Feng SJ Ge RL	2008	J Cell Sci2008，121，：	1

返回顶部每页显示：

共4页首页上一页第1页下一页末页 /4 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示