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| 1 | 健康成人动脉粥样硬化斑块易感性和血栓形成的生物标志物变化与极端空气污染水平相关:北京AIRCHD研究显示文摘空气污染与心血管事件恶化的病理生理机制尚不完全清楚。该文探讨环境空气污染是否可以触发易损斑块.通过全身炎症途径促进血栓形成。方法:在北京AIRCHD研究中.2014-2016年间对73名健康成年人[年龄(23.3±5.4)岁]进行了随访。研究者使用线性混合效应模型评估了空气污染物与动脉粥样硬化斑块易损性、血栓形成和炎症相关生物标志物之间的关系,并使用中介效应分析(mediation analyses)探讨涉及的生物学途径。通过受试者工作特征(receiver operating characteristic,ROC)曲线分析评估每种生物标记物预测环境空气污染暴露的能力。 | 刘青 叶鹏 Xu H Wang T Liu S Brook RD Feng B Zhao Q Song X Yi T Chen J Zhang Y Wang Y Zheng L Rajagopalan S Li J Huang W | 2019 | 中华高血压杂志2019，27，4： | 13 |
| 2 | Oxidative stress and extracellular matrices after hepatectomy and liver transplantation in rats显示文摘AIM:To investigate oxidative stress(OS)-mediated damage and the behavior of extracellular matrices in various rat models because shear stress with portal hypertension and cold ischemia/warm reperfusion injury trigger the liver regeneration cascade after surgery. These injuries also cause fatal liver damage.METHODS: Rats were divided into four groups according to the surgery performed: control; hepatectomy with 40% liver remnant(60% hepatectomy); orthotopic liver transplantation(OLT) with whole liver graft(100% OLT); and split OLT(SOLT) with 40% graft(40% SOLT). Survival was evaluated. Blood and liver samples were collected at 6 h after surgery. Biochemical and histopathological examinations were performed. OSinduced damage, 4-hydroxynonenal, ataxia-telangiectasia mutated kinase, histone H2AX, phosphatidylinositol 3-kinase(PI3K) and Akt were evaluated by western blotting. Behavior of extracellular matrices, matrix metalloproteinase(MMP)-9, MMP-2, tissue inhibitor of metalloproteinase(TIMP)-1 and TIMP-2 were also evaluated by western blotting and zymography. RESULTS: Although 100% OLT survived, 60% hepatectomy and 40% SOLT showed poor survival. Histopathological, immunohistological, biochemical and protein assays revealed that 60% hepatectomy, 100% OLT and 40% SOLT showed liver damage. PI3K and Akt were decreased in 60% hepatectomy and 40% SOLT. For protein expression, 40% SOLT showed differences in MMP-9, MMP-2 and TIMP-2. TIMP-1 showed differences in 60% hepatectomy and 40% SOLT. For protein activity, MMP-9 demonstrated significant differences in 60% hepatectomy, 100% OLT and 40% SOLT. CONCLUSION: Under conditions with an insufficient liver remnant, prevention of OS-induced damage via the Akt/PI3K pathway may be key to improve the postoperative course. MMP-9 may be also a therapeutic target after surgery. | Tomohide Hori Shinji Uemoto Feng Chen Lindsay B Gardner Ann-Marie T Baine Toshiyuki Hata Takayuki Kogure Justin H Nguyen | 2014 | World Journal of Hepatology2014，6，2： | 7 |
| 3 | Src homology 2 domain-containing inositol-5-phosphatase 1 (SHIP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism显示文摘 | An H Xu H Zhang M Zhou J Feng T Qian C Qi R Cao X | 2006 | 第二军医大学学报2006，27，1： | 6 |
| 4 | Simple and reproducible hepatectomy in the mouse using the clip technique显示文摘AIM: To investigate the reliability of massive hepatectomy models by using clip techniques. METHODS: We analyzed anatomical findings in 100 mice following massive hepatectomy induced by liver reduction > 70%. The impact of various factors in the different models was also analyzed, including learning curves, operative time, survival curves, and histopathological findings.RESULTS: According to anatomical results, models with 75%, 80%, and 90% hepatectomy produced massive hepatectomy. Learning curves and operative times were most optimal with the clip technique. Each hepatectomy performed using the clip technique produced a reasonable survival curve, and there were no differences in histopathological findings between the suture and clip techniques. CONCLUSION: Massive hepatectomy by the clip technique is simple and can provide reliable and relevant data. | Tomohide Hori Norifumi Ohashi Feng Chen Ann-Marie T Baine Lindsay B Gardner Toshiyuki Hata Shinji Uemoto Justin H Nguyen | 2012 | World Journal of Gastroenterology2012，18，22： | 4 |
| 5 | Variations in Wool Growth with Nutrient Supply in Northern China显示文摘Field studies on essessment of nutritional status of the grazing sheep were carried out in each of the three major grassland regions, the eastern Inner Mongolia and beyond grassland, the Inner Mongolia - Ningxia - Gansu grassland and the Xinjiang grassland, in northern China. The results obtained showed that the wool production of fine wool sheep in these regions varied between regions and seasons, with similar seasonal patterns in all regions and that reducing the seasonal variations in nutrient supply would enhance wool production substantially. Nutritional limitations to wool growth of the grazing sheep in these regions were suggested, those were: the shortage of protein supply in winter and early spring; the poor quality of much of the pasture and the hay used as supplements, the low energy intake during winter which probably necessitated the use of body stores to maintain body temperature. | D X Lu,Iner(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)Z C Feng,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)H R Wang,(Mongolia Academy of Animal Sciences.Hohhot City.Inner Mongolia Autgolia Autonmous Region.PRC)R Z Yang,(Xinjiang Institute of Animal Science.Xinjiang Academy of Animal Science.Yiu Hou Road.Urumqi.Xinjiang Uygur Autonomous Region PRC)C T Ma,(Chinese Academy of Agricultural Sciences.Lanzhou.Gansu.PRC)D B Purser,(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)J R Lindsay(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014)D W Peter(CSIRO Division of Animal Production.Laboratory for Rural Research.Private Bag.P.O.Wembley.Western Australia 6014) | 1997 | 畜牧与饲料科学1997，22，S1： | 3 |
| 6 | Factors affecting phosphate adsorption equilibria in lake sediments显示文摘 | Ku W C Digiano F A Feng T H | 1978 | Water Res1978，12，： | 2 |
| 7 | Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study显示文摘 | Hongjie Yu Joseph T Wu Benjamin J Cowling Qiaohong Liao Vicky J Fang Sheng Zhou Peng Wu Hang Zhou Eric H Y Lau Danhuai Guo Michael Y Ni Zhibin Peng Luzhao Feng Hui Jiang Huiming Luo Qun Li Zijian Feng Yu Wang Weizhong Yang Gabriel M Leung | 2013 | The Lancet2013，，： | 2 |
| 8 | Interfacial microstructure and mechanical properties of aluminium-zinc-coated steel joints made by a modified metal inert gas welding-brazing process显示文摘 | ZHANG H T FENG J C HE P HACKL H | 2007 | Materials Characterization2007，58，7： | 1 |
| 9 | Materials Science and Engineering A显示文摘 | Zhang H T He P Feng J C | 2006 | 425:2552006，425，： | 1 |
| 10 | Specular surface measurement by using least squares light tracking technique显示文摘 | GUO H FENG P TAO T | 2010 | Optics and Lasers in Engineering2010，48，2： | 1 |
| 11 | Specific antibodies to moe- sin,a membrane-cytoskeleton linker protein,are frequently detected in patients with acquired aplastie anaemia显示文摘 | Takamatsu H Feng X Chuhjo T | 2007 | Blood2007，109，6： | 1 |
| 12 | Ambient salinity modulates the expression of sodium pumps in branchial mitochondria-fich cells of Mozambique tilapia,Oreochromis mossambicus 显示文摘 | LEE T H FENG S HILIN C H | | Zool Sci0，20，： | 1 |
| 13 | Flow patterns in the sedimentation of an elliptical particle显示文摘 | Xia Z H Connington K W Rapaka S Yue P T Feng J J Chen S Y | 2009 | J Fluid Mech2009，625，： | 1 |
| 14 | Cyclooxygenase-2- deficient mice are resistant to 1-methyl-4-phenyl 1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neu- rons in the substantia nigra 显示文摘 | Feng Z H Wang T G Li D D | 2002 | Neurosci Lett2002，329，3： | 1 |
| 15 | The protein data bank显示文摘 | Berman H M Westbrook J Feng Z K Gilliland G Bhat T N Weissig H Shindyalov L N Bourne P E | | 0，，01： | 1 |
| 16 | Hydrothermal synthesis of copper complexes of 4'-pyridyl terpyridine: from discrete monomer to zigzag chain polymer original research article显示文摘 | Feng H Zhou X P Wu T | 2006 | Inorg Chim Acta2006，359，： | 1 |
| 17 | Determination of volatile organic compounds in workplace air by multisorbent adsorption/thermal desorption-GC/MS显示文摘 | WU C H FENG C T LO Y S | 2004 | Chemosphere2004，56，1： | 1 |
| 18 | 显示文摘 | Feng P Wan Q Wang T H | 2005 | Appl Phys Lett2005，87，： | 1 |
| 19 | Decomposition of Polygons Into Simpler Components:Feature Extraction for Syntactic Pat tern Recognition 显示文摘 | FENG H Y PAVLIDIS T | 1975 | IEEE Transaction on Computers1975，24，： | 1 |
| 20 | Estimation of in situ stress along deep tunnels buried in complex geological conditions显示文摘 | ZHANG C Q FENG X T ZHOU H | 2012 | International Journal of Rock Mechanics and Mining Sciences2012，52，6： | 1 |
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