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| 1 | One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system显示文摘 | Haifeng Wan Chunjing Feng Fei Teng Shihua Yang Baoyang Hu Yuyu Niu Andy Peng Xiang Weizhen Fang Weizhi Ji Wei Li Xiaoyang Zhao Qi Zhou | 2015 | Cell Research2015，25，2： | 39 |
| 2 | Hydroxytyrosol and olive leaf extract exert cardioprotective effects by inhibiting GRP78 and CHOP expression显示文摘Myocardial infarction triggers massive biochemical changes, even cardiac cell death. Endoplasmic reticulum stress is involved in the pathology of myocardial infarction-mediated apoptosis. In the present study, myocardial cell line H9c2 cells were treated with cobalt chloride(CoCl_2) to induce hypoxia. Isoproterenol was used for two successive days to induce myocardial infarction in SD rats. The cardioprotective effect of olive leaf extract(OLE) and its main constituent hydroxytyrosol and the underlying mechanisms were evaluated. The results showed that hydroxytyrosol markedly protected H9c2 cells against CoCl_2-induced apoptosis. Hydroxytyrosol could reduce the mRNA and protein expression of GRP78 and CHOP induced by CoCl_2 in vitro. In vivo, the decreased ejection fraction and fractional shortening, increased heart weight/body ratio, the formation of infarction, disordered cardiac muscle fibers and infiltration of inflammatory cells induced by isoproterenol could be significantly ameliorated by pretreatment with OLE for a month. Similarly, OLE could also reverse the increase of GRP78 and CHOP expression induced by isoproterenol. Therefore, OLE and hydroxytyrosol exert a cardioprotective effect through endoplasmic reticulum stress, which could be a new target for the prevention and treatment of cardiovascular diseases. | Lixing Wu Yuyu Xu Zhijian Yang Qing Feng | 2018 | The Journal of Biomedical Research2018，32，5： | 4 |
| 3 | Principle and application of three-band gradient difference vegetation index显示文摘Vegetation index is a simple, effective and experiential measurement of terrestrial vegetation activity, and plays a very important role in qualitative and quantitative remote sensing. Aiming at shortages of current vegetation indices, and starting from the analysis of vegetation spectral characteristics, we put forward a new vegetation index, the three-band gradient difference vegetation index (TGDVI), and established algorithms to inverse crown cover fraction and leaf area index (LAI) from it. Theoretical analysis and model simulation show that TGDVI has high saturation point and the ability to remove the influence of background to some degree, and the explicit functional relation with crown cover fraction and LAI can be established. Moreover, study shows that TGDVI also has the ability to partly remove the influence of thin cloud. Experiment in the Shunyi District, Beijing, China shows that reasonable result can be reached using the vegetation index to retrieve LAI. We also theoretically analyzed the reason why the normalized difference vegetation index (NDVI) owns the low saturation point, and show that it is determined by the definition of NDVI and the characteristic of vegetation spectra, and is unavoidable to some degree. Meanwhile, through model simulation, we also indicate that the relationship between simple ratio vegetation index (SR) and LAI closes to a piecewise linear one instead of a linear one, which is mainly caused by the influence of background and different change rates of reflectance in red and infrared bands with LAI increasing. | TANG Shihao, ZHU Qijiang, WANG Jindi, ZHOU Yuyu & ZHAO Feng Research Center for Remote Sensing and GIS, Department of Geography, Beijing Normal University, Beijing 100875, China National Satellite Meteorological Center, China Meteorological Administration, Beijing 100081, China | 2005 | Science China Earth Sciences2005，48，2： | 4 |
| 4 | Reconfigurable photovoltaic effect for optoelectronic artificial synapse based on ferroelectric p-n junction显示文摘Neuromorphic machine vision has attracted extensive attention on wide fields.However,both current and emerging strategies still suffer from power/time inefficiency,and/or low compatibility,complex device structure.Here we demonstrate a driving-voltage-free optoelectronic synaptic device using non-volatile reconfigurable photovoltaic effect based on MoTe_(2)/α-In_(2)Se_(3) ferroelectric p-n junctions.This function comes from the non-volatile reconfigurable built-in potential in the p-n junction that is related to the ferroelectric polarization inα-In_(2)Se_(3).Reconfigurable rectification behavior and photovoltaic effect are demonstrated firstly.Notably,the figure-of-merits for photovoltaic effect like photoelectrical conversion efficiency non-volatilely increases more than one order.Based on this,retina synapse-like vision functions are mimicked.Optoelectronic short-term and long-term plasticity,as well as basic neuromorphic learning and memory rule are achieved without applying driving voltage.Our work highlights the potential of ferroelectric p-n junctions for enhanced solar cell and low-power optoelectronic synaptic device for neuromorphic machine vision. | Yanrong Wang Feng Wang Zhenxing Wang Junjun Wang Jia Yang Yuyu Yao Ningning Li Marshet Getaye Sendeku Xueying Zhan Congxin Shan Jun He | 2021 | Nano Research2021，14，11： | 2 |
| 5 | Application of silver nanoparticles to cotton fabric as an antibacterial textile finish显示文摘 | ZHANG Feng WU Xiaolan CHEN Yuyue | | 0，，04： | 1 |
| 6 | A sequence of piecewise orthogonal polynomials显示文摘 | Feng Yuyu Qi Dongxu | 1984 | SIAM Journal on Mathematical Analysis1984，15，4： | 1 |
| 7 | Study of magnetorheological brush finishing (MRBF) for concave surface of conformal optics显示文摘 | ZHANG Yun FENG Zhijing WANG Yuyue | 2012 | Advanced Materials Research2012，497，： | 1 |
| 8 | Synthesis of an amino-terminate Hyperbranched polymer and its ap- plication in reactive dyeing on cotton as a salt-free dyeing auxiliary显示文摘 | ZHANG Feng CHEN Yuyue LIN Hong | 2007 | Society of Dyes and Coloration Technology2007，123，6： | 1 |
| 9 | HBP-NH2 grafted cotton fiber: preparation and salt-free dyeing properties 显示文摘 | ZHANG Feng CHEN Yuyue LIN Hong | 2008 | Carbohydrate Polymers2008，74，： | 1 |
| 10 | Best one-sided approximation of polynomials under L1 norm显示文摘 | Deng Jiansong Feng Yuyu Chen Falai | 2002 | Journal of Computational and Applied Mathematics2002，144，12： | 1 |
| 11 | A sequence of piecewise orthogonal polynomials显示文摘 | FENG Yuyu QI Dongxu | 1984 | SlAM Journal of Mathematics1984，15，4： | 1 |
| 12 | Synthesis of an amino-terminated hyperbranched polymer and its application in reactive dyeing on cotton as a salt-free dyeing auxiliary显示文摘 | ZHANG Feng CHEN Yuyue LIN Hong | 2007 | Coloration Technology2007，123，： | 1 |
| 13 | A sequence of piecewise orthogonal polynomials显示文摘 | Feng Yuyu Qi Dongxu | 1984 | Society for Industrial and Applied Mathematics Journal of Mathematic Annual1984，15，4： | 1 |
| 14 | Synthesis of an ami-no-terminated hyperbranched polymer and its application in reactive dyeing on cotton as a salt-free dyeing auxiliary 显示文摘 | Feng Zhang Yuyue Chen Hong Lin | 2007 | Coloration Technology2007，123，： | 1 |
| 15 | Performance of Cotton Fabric Treated with an Amino-terminated Hyperbranched Pol- ymer 显示文摘 | Feng Zhang Desuo Zhang Yuyue Chert | 2008 | Fibers and Polymers2008，9，5： | 1 |
| 16 | Synthesis of an amino-terminated hyperbranched polymer and its application in reactive dyeing on cotton as a salt- free dyeing auxiliary 显示文摘 | ZHANG Feng CHEN Yuyue LIN Hong | 2007 | Coloration Technology2007，123，6： | 1 |
| 17 | HBP-NI-I2 grafted cotton fiber: Preparation and salt-free dyeing properties 显示文摘 | Feng Zhang Yuyue Chen Hong Lin | 2008 | Car- bohydrate Polymers2008，74，： | 1 |
| 18 | HBP- NH2 grafted cotton fiber: preparation and salt-free dyeing properties 显示文摘 | ZHANG Feng CHEN Yuyue LIN Hong | 2008 | Carbohydrate Polymers2008，74，2： | 1 |
| 19 | A sequence of piecewise orthogonal polynomials显示文摘 | Feng Yuyu Qi Dongxu | 1984 | Journal of Mathematic Annual1984，15，4： | 1 |
| 20 | Application of silver nanoparticles to cotton fabric as an antibacterial textile finish 显示文摘 | ZHANG Feng WU Xiaolan CHEN Yuyue | 2009 | Fibers and Polymers2009，10，4： | 1 |
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