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| 1 | 评估大气细颗粒物暴露引起的全球疾病负担的一个综合风险函数显示文摘[背景]评估由于环境空气中细颗粒物(PM2.5)长期暴露引起的疾病负担,需要了解相对风险度(RR)函数的图形和幅度。然而,在世界上很多观察到高PM2.5环境浓度的地方,都缺乏足够的直接证据确定死亡RR函数的图形。[目的]建立可用于全球PM2.5暴露范围内成人死因的RR函数:缺血性心脏病(IHD)、脑血管疾病(脑卒中)、慢性阻塞性肺病(COPD)和肺癌(LC)。建立急性下呼吸道感染(ALRI)发病的RR函数,用于估算〈5岁的儿童中死亡率和健康生活损失年数。[方法]通过整合现有的来自于环境空气污染(AAP)、二手烟草烟雾、家用固体烹饪用燃料和主动吸烟(AS)等研究的RR信息,拟合综合暴露-反应(IER)模型。采用颗粒物质的吸入剂量,通过转化AS暴露来估计全年PM2.5的暴露当量。在估算全球环境PM2.5浓度的基础上,得出各国的人群归因分数(PAFs)。[结果]与以往负担评估中使用的其他7种模型相比,IER模型是一种优越的RR预测方法。在不同国家中,归因于AAP暴露的PAF百分数各不相同,分别为:IHD,2~41;脑卒中,1~43;COPD,〈1~21;LC,〈1~25;ALRI,〈1~38。[结论]我们建立了一种以细颗粒物为基础的RR模型,它通过整合来自不同类型的燃烧所产生颗粒物排放的RR信息,涵盖全球范围的暴露。当获得新的RR信息时,可以对这个模型进行更新。 | Richard T.Burnett C.Arden Pope III Majid Ezzati Casey Olives Stephen S.Lim Sumi Mehta Hwashin H.Shin Gitanjali Singh Bryan Hubbell Michael Brauer H.Ross Anderson Kirk R.Smith John R.Balmes Nigel G.Bruce Haidong Kan Francine Laden Annette Prüss-Ustün Michelle C.Turner Susan M.Gapstur W.Ryan Diver Aaron Cohen 何蓉 张伊人 金泰廙 | 2014 | 环境与职业医学2014,31,11: | 80 |
| 2 | A community-derived classification for extant lycophytes and ferns显示文摘发展史长通知了蕨类植物分类。当我们推断进化的树的能力改善了,针对认出生来的组的分类变得逐渐地预兆、稳定。这里,我们为 lycophytes 和蕨纲植物提供一个现代、全面分类,在下面,利用一条基于社区的途径类水平。我们 monophyly 用作主要标准让 taxa,而且目的识别保存两个广泛地被接受的存在 taxa 和界限并且与我们蕨类植物发展史的理解一致。总共,这个分类对待一在 337 个类, 51 个家庭, 14 目,和二个班估计了 11 916 种类。这个分类没在 lycophyte 和蕨纲植物上作为最后的词被打算分类,而是当前的假设的概括陈述,源于最好的可得到的数据并且在问题由熟悉植物的那些大多数塑造了。我们希望它将在蕨类植物上为最近的文学的那些想要的参考用作一个资源发展史和分类,为指导未来调查的一个框架,和推进讲话的刺激。 | Eric Schuettpelz Harald Schneider Alan R. Smith Peter Hovenkamp Jefferson Prado Germinal Rouhan Alexandre Salino Michael Sundue Thafs Elias Almeida Barbara Parris Emily B. Sessa Ashley R. Field Andre Luis de Gasper Carl J. Rothfels Michael D. Windham Marcus Lehnert Benjamin Dauphin Atsushi Ebihara Samuli Lehtonen Pedro Bond Schwartsburd Jordan Metzgar Li-Bing Zhang Li-Yaung Kuo Patrick J. Brownsey Masahiro Kato Marcelo Daniel Arana Francine C. Assis Michael S. Barker David S. Barrington Ho-Ming Chang Yi-Han Chang Yi-Shan Chao Cheng-Wei Chen De-Kui Chen Wen-Liang Chiou Vinicius Antonio de Oliveira Dittrich Yi-Fan Duan Jean-Yves Dubuisson Donald R. Farrar Susan Fawcett Jose Maria Gabriel y Galan Luiz Armando de Araujo Goes-Neto Jason R. Grant Amanda L. Grusz Christopher Haufler Warren Hauk Hai He Sabine Hennequin Regina Yoshie Hirai Layne Huiet Michael Kessler Petra Korall Paulo H. Labiak Anders Larsson Blanca Leen Chun-Xiang Li Fay-Wei Li Melanie Link-Perez Hong-Mei Liu Ngan Thi Lu Esteban I. Meza-Torres Xin-Yuan Miao Robbin Moran Claudine Massi Mynssens Nathalie Nagalingum Benjamin Ollgaard Alison M. Paul Jovani B. de S. Pereira Leon R. Perrie Monica Ponce Tom A. Ranker Christian Schulz Wataru Shinohara Alexander Shmakov Erin M. Sigel Filipe Soares de Souza Lana da Silva Sylvestre Weston Testo Luz Amparo Triana-Moreno Chie Tsutsumi Hanna Tuomisto IvAn A. Valdespino Alejandra Vasco Raquel Stauffer Viveros Alan Weakley Ran Wei Stina Weststrand Paul G. Wolf George Yatskievych Xiao-Gang Xu Yue-Hong Yan Liang Zhang Xian-Chun Zhang Xin-Mao Zhou | 2016 | Journal of Systematics and Evolution2016,54,6: | 44 |
| 3 | Spontaneous rupture of hepatic hemangiomas:A review of the literature显示文摘Hepatic hemangiomas are congenital vascular malformations,considered the most common benign mesenchymal hepatic tumors,composed of masses of blood vessels that are atypical or irregular in arrangement and size. Hepatic hemangiomas can be divided into two major groups:capillary hemangiomas and cavernous hemangiomas These tumors most frequently affect females (80%) and adults in their fourth and fifth decades of life. Most cases are asymptomatic although a few patients may present with a wide variety of clinical symptoms,with spontaneous or traumatic rupture being the most severe complication. In cases of spontaneous rupture,clinical manifestations consist of sudden abdominal pain,and anemia secondary to ahaemoperitoneum. Disseminated intravascular coagulopathy can also occur. Haemodynamic instability and signs of hypovolemic shock appear in about one third of cases. As the size of the hemangioma increases,so does the chance of rupture. Imaging studies used in the diagnosis of hepatic hemangiomas include ultrasonography,dynamic contrast-enchanced computed tomography scanning,magnetic resonance imaging,hepatic arteriography,digital subtraction angiography,and nuclear medicine studies. In most cases hepatic hemangiomas are asymptomatic and should be followed up by means of periodic radiological examination. Sur gery should be restricted to specific situations. Absolute indications for surgery are spontaneous or trau m atic rupture with hemoperitoneum,intratumoral blee ding and consumptive coagulopathy (Kassabach-Merrit syndrome). In a patient presenting with acute abdo minal pain due to unknown abdominal disease,sponta neous rupture of a hepatic tumor such as a hemangio ma should be considered as a rare differential diagnosis. | Marcelo AF Ribeiro Francine Papaiordanou Juliana M Gonalves Eleazar Chaib | 2010 | World Journal of Hepatology2010,2,12: | 12 |
| 4 | cDNA-AFLP结合BSA研究马铃薯晚疫病菌小种特异无毒基因差异表达片段显示文摘通过对具有 6个无毒基因不同表型的马铃薯晚疫病菌构建的 4个混合池进行cDNA AFLP分析 ,得到与 6个与无毒基因相关的差异表达片段 (TDFs) 85条 ,其中与无毒基因Avr1相关的为 2 0条 ,Avr2 2 8条 ,Avr3 Avr10 Avr1116条 ,Avr4 2 1条。差异表达片段大小主要分布在 10 0bp和 30 0bp之间 ,最小片段为 6 0bp ,最大片段 4 40bp。 | 郭军 屈冬玉 王晓武 金黎平 谢开云 Rays Jiang Francine Govers | 2004 | 中国马铃薯2004,18,1: | 12 |
| 5 | Technical and conceptual considerations forusing animated stimuli in studies of animalbehavior显示文摘Rapid technical advances in the field of computeropened new avenues in animal behavior research.animation (CA) and virtual reality (VR) haveAnimated stimuli are powerful tools as theyoffer standardization, repeatability, and complete control over the stimulus presented, thereby"reducing" and "replacing" the animals used, and "refining" the experimental design in line withthe 3Rs. However, appropriate use of these technologies raises conceptual and technical questions.In this review, we offer guidelines for common technical and conceptual considerations related tothe use of animated stimuli in animal behavior research. Following the steps required to create ananimated stimulus, we discuss (I) the creation, (11) the presentation, and (111) the validation of CAsand VRs. Although our review is geared toward computer-graphically designed stimuli, consider-ations on presentation and validation also apply to video playbacks. CA and VR allow both new be-havioral questions to be addressed and existing questions to be addressed in new ways, thus weexpect a rich future for these methods in both ultimate and proximate studies of animal behavior. | Laura CHOUINARD-THULY Stefanie GIERSZEWSKI Gil G. ROSENTHAL Simon M. READER Guillaume RIEUCAU Kevin L. Woo Robert GERLAI Cynthia TEDORE Spencer J. INGLEY John R. STOWERS Joachim G.FROMMENI Francine L. DOLINS Klaudia WITTE | 2017 | Current Zoology2017,63,1: | 10 |
| 6 | 与马铃薯晚疫病菌无毒基因Avr1连锁的AFLP标记显示文摘以具有和不具有无毒基因Avr1表现型的马铃薯晚疫病菌株80029(AVR1)和88133(avr1)以及其杂交F1代50个菌株群体为试材,限制性内切酶PstI和HhaI为酶切组合,采用荧光AFLP技术和混合分组分析法(BSA),通过256对引物筛选得到了5个与Avr1连锁的候选AFLP标记并进行了菌株个体验证,遗传分析表明5个标记中有2个标记与Avr1连锁且在F1代中共分离,无交换重组发生。 | 郭军 Rob Weide 屈冬玉 王晓武 谢开云 Francine Govers | 2005 | 中国农业科学2005,38,9: | 10 |
| 7 | EMDR治疗:适应性信息加工、临床应用及研究介绍显示文摘恭祝中国EMDR学组的成立,同时对所有致力于帮助那些遭遇痛苦的人们减轻伤痛的同仁们致以敬意。谢谢给我这个机会,让我能够对EMDR(眼动脱敏再加工)的最新进展及其理论基础作些阐述。过去二十年来,很多事情都发生了变化,也需要作些澄清。 | Francine Shapiro 杨渝川 | 2011 | 西华大学学报(哲学社会科学版)2011,30,1: | 6 |
| 8 | 马铃薯晚疫病菌小种特异无毒基因候选表达序列的cDNA-AFLP鉴定显示文摘利用具有6个无毒基因不同表现型且处于萌发中的静孢子时期的马铃薯晚疫病菌构建4个混 合池,通过cDNA AFLP分析,共获得85个与无毒基因相关的差异表达片段,其中与无毒基因Avr1、Avr2、 Avr3 Avr10 Avr11、Avr4相关的差异表达片段分别为20,28,16和21个。将这些差异表达片段对20个晚疫 病病菌个体进行无毒基因差异表达验证,得到1个无毒基因连锁群Avr3 Avr10 Avr11的候选片段,即 A11T13Avr3 10 11S157;无毒基因Avr4的候选片段2个,即A24T19Avr4S122和A24T24Avr4S142。Blast分析 表明:A11T13Avr3 10 11S157与马铃薯晚疫病菌萌发孢子囊(germinatingsporangium)EST(expressed sequencetag)库中的序列PG001F10.XT7同源;A24T19Avr4S122与晚疫病菌萌发中静孢子(germinating cyst)EST库中的PH051G10.XT7部分序列完全一致,而A24T24Avr4S142与PH051G10.XT7具有98%的 同源性。这些结果将促进通过电子克隆并结合RACE(RapidAmplificationofcDNAEnds)技术获得全长的无 毒基因Avr4。 | 郭军 屈冬玉 王晓武 金黎平 谢开云 Rays H.Y.Jiang Francine Govers | 2005 | 园艺学报2005,32,1: | 6 |
| 9 | Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice显示文摘 | Tiphaine Le Roy Marta Llopis Patricia Lepage Aurélia Bruneau Sylvie Rabot Claudia Bevilacqua Patrice Martin Catherine Philippe Francine Walker André Bado Gabriel Perlemuter Anne-Marie Cassard-Doulcier Philippe Gérard | 2013 | Gut2013,,12: | 3 |
| 10 | The metabolic syndrome in children and adolescents显示文摘 | Paul Zimmet George Alberti Francine Kaufman Naoko Tajima Martin Silink Silva Arslanian Gary Wong Peter Bennett Jonathan Shaw Sonia Caprio | 2007 | The Lancet2007,,9579: | 3 |
| 11 | Edge Computing Based Applications in Vehicular Environments:Comparative Study and Main Issues显示文摘Despite the expanded efforts,the vehicular ad-hoc networks(VANETs)are still facing many challenges such as network performances,network scalability and context-awareness.Many solutions have been proposed to overcome these obstacles,and the edge computing,an extension of the cloud computing,is one of them.With edge computing,communication,storage and computational capabilities are brought closer to end users.This could offer many benefits to the global vehicular network including,for example,lower latency,network off-loading and context-awareness(location,environment factors,etc.).Different approaches of edge computing have been developed:mobile edge computing(MEC),fog computing(FC)and cloudlet are the main ones.After introducing the vehicular environment background,this paper aims to study and compare these different technologies.For that purpose their main features are compared and the state-of-the-art applications in VANETs are analyzed.In addition,MEC,FC,and cloudlet are classified and their suitability level is debated for different types of vehicular applications.Finally,some challenges and future research directions in the fields of edge computing and VANETs are discussed. | Leo Mendiboure Mohamed-Aymen Chalouf Francine Krief | 2019 | Journal of Computer Science & Technology2019,34,4: | 3 |
| 12 | Further extension of the opine concept: Plasmids in Agrobacterium rhizogenes cooperate for opine degradation显示文摘 | Annik Petit Chantal David Gary A. Dahl Jeffrey G. Ellis Pierre Guyon Francine Casse-Delbart Jacques Tempé | 1983 | MGG Molecular & General Genetics1983,,2: | 3 |
| 13 | Prospective Study of Sudden Cardiac Death Among Women in the United States显示文摘 | Christine M. Albert Claudia U. Chae Francine Grodstein Lynda M. Rose Kathryn M. Rexrode Jeremy N. Ruskin Meir J. Stampfer JoAnn E. Manson | 2003 | Circulation: Journal of the American Heart Association2003,,16: | 3 |
| 14 | 乳汁免疫和猪流行性腹泻病毒病疫苗:历史和现状(译文)显示文摘由于肠道病毒感染导致仔猪在发病率、死亡率和生产能力丧失方面的影响,每年给养猪者带来数百万美元的损失。2013—2014年间,猪流行性腹泻病毒(PEDV)病的暴发给美国养猪业带来了9亿~18亿美元的经济损失。被动乳汁免疫被认为是保护新生哺乳仔猪免受PED等肠道疾病危害的最有希望和有效的方法。通过乳汁免疫被动保护哺乳仔猪的效果依赖于病原特异性IgA浆细胞转运至乳腺的数量和乳汁中分泌型IgA的积累程度,这种免疫途径被定义为'肠-乳腺-sIgA轴'。由于胎盘的不可穿透性,新生仔猪处于无免疫球蛋白的状态,对很多的传染性病原体极易感。它们仅依靠来源于母源的初乳和乳汁抗体获得被动保护。先前开发的关于猪传染性胃肠炎病毒(TGEV)病的活疫苗和灭活疫苗,提供了对母源性免疫和仔猪被动保护机制的理解。在这篇文章中,综述了猪传染性胃肠炎病毒诱导乳汁免疫的研究进展,并指出对当前养猪业正努力控制的猪流行性腹泻病毒感染和相关疫苗的研究方向。同时研究和鉴别出影响乳汁免疫和'肠-乳腺-sIgA轴'的各种因素,有助于改善妊娠母猪预防猪流行性腹泻病毒感染以及改进其它肠道病原用疫苗方案,从而达到提升整个猪群的免疫力、猪群健康和企业生产力的目的。 | Langel Stephanie N Paim Francine Chimelo Lager Kelly M Vlasova Anastasia N Saif Linda J 吕茂杰 | 2017 | 养猪2017,,1: | 3 |
| 15 | Larvicidal activities of hydro-ethanolic extracts of three Cameroonian medicinal plants against Aedes albopictus显示文摘Objective: To investigate the larvicidal activity of Syzygium guineense(Myrtaceae)(S. guineense), Monodora myristica and Zanthoxylum heitzii(Rutaceae)(Z. heitzii) extracts against Aedes albopictus(Ae. albopictus).Methods: The larvicidal activity of the hydro-ethanolic extracts from these plant species was assessed at three different concentrations(50, 100 and 200 mg/L) on first-instar of Ae. albopictus larvae in comparison with untreated controls. Mortality rate was recorded daily for a period of 12 days. The values of LC_(50) and lethal time killing 50% of the tested individuals(LT_(50)) were calculated using the log-probit analysis.Results: The root extract of S. guineense exhibited the best activity with 100% mortality after 8 days of treatment at 200 mg/L, followed by the fruit extract of Z. heitzii with83.33% mortality at the same concentration. Nonetheless, larvae were most susceptible to the fruit extract of Z. heitzii both in terms of LC_(50)(39.89 mg/L) and LT_(50)(145.68 h). A statistically significant difference between the control and the group treated at 200 mg/L was noticed in all the extracts.Conclusions: The present study shows that the hydro-ethanolic extracts of S. guineense,Monodora myristica and Z. heitzii tested have significant larvicidal activity. These preliminary results are of great interest and some of these plant species can be proposed for the formulation of new bioinsecticides to control Ae. albopictus populations. | Tankeu Nzufo Francine Biapa Nya Prosper Cabral Pieme Constant Anatole Moukette Moukette Bruno Nanfack Pauline Ngogang Yonkeu Jeanne | 2016 | Asian Pacific Journal of Tropical Biomedicine2016,6,11: | 2 |
| 16 | EMDR、适应性信息加工与个案概念化(上)显示文摘EMDR是一个整合性的、以咨客为中心的心理治疗方法,它着重于大脑的信息加工系统、烦扰经历的记忆,这些病理学基础不是由器质性的损伤导致的。EMDR强调对临床情境有作用的经历,和那些需要带领咨客达到更健康的心理状态的经历。EMDR作为以经验为主的支持治疗,本文综述其历史、发展和研究,在阐述适应性信息加工模型之后,用一个延续的个案实例来说明了EMDR的个案概念化和8个阶段的治疗。这个方法用于加工那些建立病理学基础的和触发当前功能失调的早期记忆,并为将来恰当的行为提供模板,包括克服技能和(或)发展性的不足所需的知识与行为。整合的EMDR与家庭系统观点的好处是可以提供最综合的治疗效果。 | Francine Shapiro 魏赓 | 2011 | 西华大学学报(哲学社会科学版)2011,30,5: | 2 |
| 17 | 上海小姐--评《长恨歌》显示文摘二○○八年五月四日的《纽约时报》书评版罕见地以整版篇幅,发表了一组关于中国当代小说的评论,包括了对《长恨歌》、《生死疲劳》、《狼图腾》、《为人民服务》英译本的评论以及对当代流行小说的介绍。这是英语界少有的对中国当代文学的集束性关注,也表明了随着中国影响力的提升,当代文学也开始受到西方主流媒体的关注。现编译如下,供读者参考。 | 弗朗辛·普罗斯(Francine Prose) 苏妙(译) | 2008 | 当代作家评论2008,,6: | 2 |
| 18 | Ranibizumab versus Bevacizumab for neovascular age-related macular degeneration. Results from the GEFAL noninferiority randomized trial显示文摘 | Laurent Kodjikian Eric H. Souied Gérard Mimoun Martine Mauget-Fa?sse Francine Behar-Cohen Evelyne Decullier Laure Huot Gilles Aulagner | 2013 | Ophthalmology2013,,: | 2 |
| 19 | Immunobiology of Dendritic Cells显示文摘 | Jacques Banchereau Francine Briere Christophe Caux Jean Davoust Serge Lebecque Yong-Jun Liu Bali Pulendran Karolina Palucka | 2000 | Annual Review of Immunology2000,,: | 2 |
| 20 | Impact of Caudal Fin Shape on Thrust Production of a Thunniform Swimmer显示文摘Tuna,known for high endurance cruising,have already inspired several underwater robots and swimming studies.This study uses a biomimetic robotic tuna to investigate how different caudal fin planform geometries affect the thrust production and flow structures during Body and/or Caudal Fin(BCF)swimming.The robot was tethered to a circulating water tunnel,and swimming was simulated by moving water at a constant speed relative to the stationary robot.Three differently shaped caudal fins were tested,one rectangular,one elliptical,and one swept.Area,aspect ratio,and rigidity were kept constant between the three fins to ensure that the effect of caudal fin shape could be isolated.The fins were tested at three freestream velocities and four Strouhal numbers(St)so that comparisons between the fins could be made for a variety of swimming scenarios.The swept fin,which is the tested caudal fin most similar to one found on a fusiform swimmer,had the greatest thrust potential at high St,followed by the elliptical fin.The rectangular fin generally produced the least thrust.It was shown that in addition to producing the most thrust,the swept fin also best stabilized the leading edge vortex that developed during the second half of the stroke. | Alexander Matta Hodjat Pendar Francine Battaglia Javid Bayandor | 2020 | Journal of Bionic Engineering2020,17,2: | 2 |