|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Development of 3D bioprinting:From printing methods to biomedical applications显示文摘Biomanufacturing of tissues/organs in vitro is our big dream,driven by two needs:organ transplantation and accurate tissue models.Over the last decades,3D bioprinting has been widely applied in the construction of many tissues/organs such as skins,vessels,hearts,etc.,which can not only lay a foundation for the grand goal of organ replacement,but also be served as in vitro models committed to pharmacokinetics,drug screening and so on.As organs are so complicated,many bioprinting methods are exploited to figure out the challenges of different applications.So the question is how to choose the suitable bioprinting method?Herein,we systematically review the evolution,process and classification of 3D bioprinting with an emphasis on the fundamental printing principles and commercialized bioprinters.We summarize and classify extrusion-based,dropletbased,and photocuring-based bioprinting methods and give some advices for applications.Among them,coaxial and multi-material bioprinting are highlighted and basic principles of designing bioinks are also discussed. | Zeming Gu Jianzhong Fu Hui Lin Yong He | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，5： | 11 |
| 2 | Why choose 3D bioprinting?Part II:methods and bioprinters显示文摘Classification of 3D bioprinting As we mentioned in the last editorial,3D printing,also known as additive manufacturing,could be considered as the reverse process of potato cutting,automatically assembling sliced potato,shredded potato,diced potato to integrity[1].Generally speaking,cell-laden 3D bioprinting can be classified into three types:extrusion-based,droplet-based and photocuring-based bioprinting according to different printing principles.Extrusion-based bioprinting squeezes out continuous hydrogel fibers to set up structures;dropletbased bioprinting generates droplets as the basic unit for biofabrication;and photocuring-based bioprinting utilizes the characteristics of light-sensitive materials,to stack 3D models layer-by-layer.Different bioprinting approaches own diverse characteristics facing various scenarios and have specific requirements for bioinks. | Yong He Zeming Gu Mingjun Xie Jianzhong Fu Hui Lin | 2020 | Bio-Design and Manufacturing2020，3，1： | 2 |
| 3 | Late Carboniferous-Early Permian Volcanic Event Deposits and Stratigraphic Correlation in Shandong Province and Its Adjacent Regions显示文摘Deposits of 10 volcanic events of 6 stages have been discovered by the authors after detailed field and lab studies of the Benxi and Taiyuan Formations in Shandong Province and its adjacent regions. They show certain temporal-spatial distribution characteristics. Volcanic fragments were probably derived from two different volcanic sources north and south of the North China Platform, while the magma of the two volcanic sources was probably derived from the lower crust. A new stratigraphic correlation scheme is put forward for the Benxi and Taiyuan Formations in this region on the basis of previous biostratigraphic work with the regionally widespread volcanic event layers as the marker bed for the isochronous stratigraphic correlation on a super-regional scale and in conjunction with the maximum transgressive event layers. | Zhong Rong, Institute of Geomechanics, Chinese Academy of Geological Sciences, BeijingSun Shanping and Fu Zeming China University of Geosciences, Beijing Xu Niansheng, Xu Heling and Zhong Rong | 1996 | Acta Geologica Sinica(English Edition)1996，70，4： | 1 |
| 4 | The roles of Eu 2+ and Dy 3+ in the blue long-lasting phosphor Sr 2 MgSi 2 O 7 : Eu 2+ , Dy 3+显示文摘 | Chaoshu Shi Yibing Fu Bo Liu Guobin Zhang Yonghu Chen Zeming Qi Xixian Luo | 2006 | Journal of Luminescence2006，，： | 1 |
| 5 | Cost-Effective Fiber Multiplexing System Based on Low Coherence Interferometers and Application to Temperature Measurement显示文摘基于低连贯的 interferometric 原则,一个划算的所有纤维 Mach-Zehnder multiplexing 系统被建议并且示威。系统由二干涉仪组成:察觉到干涉仪和解调干涉仪。由以稳定的速度常常来回扫描一根光悦耳的延期线,察觉到有不同光路径的纤维能是时间的讯问了。系统试验性地被证明与好稳定性和低系统噪音有高效。系统的 multiplexing 能力也被调查。测量包围温度的一个实验被执行。12 m/ 的敏感?? | Meng JIANG Zhongze ZHAO Kun LI Zeming WANG Yage ZHAN Hongying ZHOU Fu YANG | 2016 | Photonic Sensors2016，6，4： | 0 |
| 6 | The Primal Exploration of Space launch and Manned Lunar-landing显示文摘The lunar-landing is the continuity of manned spaceflight engineering. Comparing with the manned spacecraft engineering, it requires more reliability , larger scale, and more funds. On the basis of China’s achievements and the experiences of foreign countries, the paper brings forward the idea that using the existing transportation technology to send the launch vehicles and cosmonauts to the near-earth orbit in batches, assembling the components together on the space-launch platform, and then launching them to the moon to fulfill our dream of manned landing on the moon. The paper also discusses the space launch platform and the launching ways. | Zhang Zeming Jiang Yi Fu Debin | 2006 | 工程科学(英文版)2006，4，4： | 0 |
| 7 | The Relationship between the Distribution of Thick Coal Belts and the Late Carboniferous-Early Early Permian Marine Transgression-Regression in the North China Platform显示文摘Four great second-order transgressions occurred during the Late Carboniferous to early Early Permian and they came from both the eastern and western sea areas in the North China Platform. As time went on, depocentres, depositional extent, transgression directions, coastline position and distribution of minable coal seams were changing continuously. The third great second-order transgression occurring at the beginning of the early Early Permian marks the maximum transgression period and before its arrival, i.e. at the close of the late Late Carboniferous, there was the super-regional coal-forming environment. During the second, third and fourth transgressions, the northern North China Platform was all along situated on the transgressive margin of the epicontinental sea and became the major distribution area of thick coal belts because it maintained a coal-forming environment for a long period of time from the close of the late Late Carboniferous to the Early Permian. | ZHONG Rong FU Zeming | 1998 | Acta Geologica Sinica(English Edition)1998，72，1： | 0 |
| 8 | DNA repair-and nucleotide metabolism-related genes exhibit differential CHG methylation patterns in natural and synthetic polyploids (Brassica napus L.)显示文摘Polyploidization plays a crucial role in the evolution of angiosperm species.Almost all newly formed polyploids encounter genetic or epigenetic instabilities.However,the molecular mechanisms contributing to genomic instability in synthetic polyploids have not been clearly elucidated.Here,we performed a comprehensive transcriptomic and methylomic analysis of natural and synthetic polyploid rapeseeds(Brassica napus).Our results showed that the CHG methylation levels of synthetic rapeseed in different genomic contexts(genes,transposon regions,and repeat regions)were signi fi cantly lower than those of natural rapeseed.The total number and length of CHG-DMRs between natural and synthetic polyploids were much greater than those of CG-DMRs and CHH-DMRs,and the genes overlapping with these CHG-DMRs were signi fi cantly enriched in DNA damage repair and nucleotide metabolism pathways.These results indicated that CHG methylation may be more sensitive than CG and CHH methylation in regulating the stability of the polyploid genome of B.napus.In addition,many genes involved in DNA damage repair,nucleotide metabolism,and cell cycle control were significantly differentially expressed between natural and synthetic rapeseeds.Our results highlight that the genes related to DNA repair and nucleotide metabolism display differential CHG methylation patterns between natural and synthetic polyploids and reveal the potential connection between the genomic instability of polyploid plants with DNA methylation defects and dysregulation of the DNA repair system.In addition,it was found that the maintenance of CHG methylation in B.napus might be partially regulated by MET1.Our study provides novel insights into the establishment and evolution of polyploid plants and offers a potentialidea for improving the genomic stability of newly formed Brassica polyploids. | Liqin Yin Zhendong Zhu Liangjun Huang Xuan Luo Yun Li Chaowen Xiao Jin Yang Jisheng Wang Qiong Zou Lanrong Tao Zeming Kang Rong Tang Maolin Wang Shaohong Fu | 2021 | Horticulture Research2021，8，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员