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| 1 | Voxel-based analyses of magnetization transfer imaging of the brain in hepatic encephalopathy显示文摘AIM: To evaluate the spatial distribution of cerebral abnormalities in cirrhotic subjects with and without hepatic encephalopathy (HE) found with magnetization transfer imaging (MTI).METHODS: Nineteen cirrhotic patients graded from neurologically normal to HE grade 2 and 18 healthy control subjects underwent magnetic resonance imaging. They gave institutional-review-board-approved written consent. Magnetization transfer ratio (MTR) maps were generated from MTI. We tested for significant differences compared to the control group using statistical non-parametric mapping (SnPM) for a voxelbased evaluation.RESULTS: The MTR of grey and white matter was lower in subjects with more severe HE. Changes were found in patients with cirrhosis without neurological defi cits in the basal ganglia and bilateral white matter. The loss in magnetization transfer increased in severity and spatial extent in patients with overt HE. Patients with HE grade 2 showed an MTR decrease in white and grey matter: the maximum loss of magnetization transfer effect was located in the basal ganglia [SnPM (pseudo-)t = 17.98, P = 0.0001].CONCLUSION: The distribution of MTR changes in HE points to an early involvement of basal ganglia and white matter in HE. | Falk R Miese Hans-Jrg Wittsack Gerald Kircheis Arne Holstein Christian Mathys Ulrich Mdder Mathias Cohnen | 2009 | World Journal of Gastroenterology2009，15，41： | 2 |
| 2 | The systemic amyloidoses 显示文摘 | Falk R H Comenzo R L Skinner M | 1997 | N Engl J Med1997，337，13： | 1 |
| 3 | Definition of Organ Involvement and Treatment Response in Immunoglobulin Light Chain Amyloidosis(AL): a Consensus Opinion from the 10th International Symposium on Amyloid and Amyloidosis, Tours, France, 18-22 April 2004显示文摘 | Gertz M A Comenzo R Falk R H | 2005 | Am J Hematol2005，79，4： | 1 |
| 4 | The in vitro stabilising effect of polyetheretherketone cages versus a titanium cage of similar design for anterior lumbar interbody fusion显示文摘 | M Spruit R G Falk L Beckmann | 2005 | Eur Spine J2005，14，8： | 1 |
| 5 | Lymphoepithelial cysts of the pancreas:a management dilemma显示文摘Pancreatic lymphoepithelial cysts(LECs) are rare,benign lesions that are typically unexpected post-operative pathological findings. We aimed to review clinical, radiological and pathological features of LECs that may allow their preoperative diagnosis. Histopathology databases of two large pancreatic units were searched to identify LECs and notes reviewed to determine patient demographic details, mode of presentation, investigations, treatment and outcome. Five male and one female patients were identified. Their median age was 60 years. Lesions were identified on computed tomography performed for abdominal pain in two patients, and were incidentally observed in four patients. Five LECs were located in the tail and one in the body of the pancreas, with a median cyst size of 5 cm. Obtaining cyst fluid was difficult and a largely acellular aspirate was yielded. The pre-operative diagnosis was mucinous cystic neoplasm in all patients. This series of patients were treated distal pancreatectomy and splenectomy. A retrospective review of radiological examinations suggested that LECs have a relatively low signal on T2 imaging and a high signal intensity on T1 weighted images. LECs appear more common in elderly males, and are typically incidental, large, unilocular cysts. Close attention to signal intensity on MRI may allow preoperative diagnosis of these lesions. | Julie Martin Keith J Roberts Maria Sheridan Gavin A Falk Daniel Joyce R Matthew Walsh Andrew M Smith Gareth Morris-Stiff | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，5： | 1 |
| 6 | Nonconforming finite elements for the Stokes problems显示文摘 | Crouzeix M Falk R S | 1989 | Math Comp1989，52，2： | 1 |
| 7 | A prospective,randomized,and controlled study of fluid management in children with head injury:lactated Ringer's solution versus hypertonic saline显示文摘 | Simma B Barger R Falk M | 1998 | Crit Care Med1998，26，7： | 1 |
| 8 | A critical evaluation of cohesive zone models of dynamic fracture 显示文摘 | Falk M L Needman A Rice J R | 2001 | Journal de Physique IV2001，，： | 1 |
| 9 | Nonconforming finite elements for the stokes problems显示文摘 | Crouzeix M Falk R S | 1989 | Math Comp1989，52，2： | 1 |
| 10 | External noninvasive tempo- rary cardiac pacing : clinical trials 显示文摘 | Zoll P M Zoll R H Falk R H | 1985 | Circulation1985，71，5： | 1 |
| 11 | Green-to-red photoconvertible fluorescent proteins: Tracking cell and protein dynamics on standard wide-field mercury arc-based microscopes显示文摘 | Baker S M Buckheit R W Falk M M | 2010 | BMC Cell Biology2010，11，1： | 1 |
| 12 | Deposition of large particles in human lung显示文摘 | Svartengren M Falk R Linnman L | 1987 | Exp Lung Res1987，12，1： | 1 |
| 13 | Transitional cell carcinoma in renal transplant recipients:the influence of compound analgesics显示文摘 | Swindle P Falk M Rigby R | | 0，，： | 1 |
| 14 | A prospective, randomized, and controlled study of fluid management in children with severe head injury:lactated Ringer's solution versus hypertonic saline 显示文摘 | Simma B Burger R Falk M | 1998 | Crit Care Med1998，26，7： | 1 |
| 15 | Establishment of TEST-yolk buffer enhanced sperm penetration assay limits for fertile males显示文摘 | Falk R M Silverberg K M Fetterolf P M Kirchner F K Rogers B J | 1990 | Fertil Steril1990，54，1： | 1 |
| 16 | Hyperthermia in oncology显示文摘 | Falk M H Issels R D | 2011 | International Journal of Hyperthermia2011，1，： | 1 |
| 17 | Definition of organ involve-ment and treatment response in immunoglobulin light chain amyloidosis(AL):a consensus opinion from the 10th international symposium onamyloid and amyloidosis显示文摘 | Gertz M A Comenzo R Falk R H | 2005 | American Journal of Hematology2005，79，4： | 1 |
| 18 | Parasitical control trape powdery mildew by the mycoparasite Ampelomyces quisqualis 显示文摘 | Falk S P Gadourg D M Pearsoa R C | 1995 | Phytopathology1995，85，： | 1 |
| 19 | Environmental controls over carbon dioxide and water vapor exchange of terrestrial vegetation显示文摘 | B.E Law E Falge L Gu D.D Baldocchi P Bakwin P Berbigier K Davis A.J Dolman M Falk J.D Fuentes A Goldstein A Granier A Grelle D Hollinger I.A Janssens P Jarvis N.O Jensen G Katul Y Mahli G Matteucci T Meyers R Monson W Munger W Oechel R Olson K Pilegaard K | 2002 | Agricultural and Forest Meteorology2002，，1： | 1 |
| 20 | The role of matrix dislocations in the superplastic deformation of a copper alloy 显示文摘 | Falk M Howell P R Dunlop G L | 1986 | Acta Metal1986，34，： | 1 |
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