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| 1 | Geminivirus satellite-encoded βC1 activates UPR,induces bZIP60 nuclear export,and manipulates the expression of bZIP60 downstream genes to benefit virus infection显示文摘UPR is a conserved response in eukaryotes and can alleviate endoplasmic reticulum(ER)stresses induced by abiotic and biotic stresses.The interactions between UPR and plant RNA viruses have been documented,while the interplays between UPR and plant DNA viruses remain unknown.Using tomato yellow leaf curl China virus(TYLCCNV)and its associated betasatellite(TYLCCNB)as a model,we indicate that TYLCCNBβC1 is a major inducer of UPR and can upregulate the expression of b ZIP60,a transcription factor in Nicotiana benthamiana plants.Treatment using ER stress inducers or overexpression of Nbb ZIP60 increasesβC1 accumulation and benefits TYLCCNV/TYLCCNB infection in N.benthamiana plants,and vice versa.In the TYLCCNV/TYLCCNB-infected or theβC1-expressing cells,Nbb ZIP60 is exported from the nucleus to the nuclear periphery via the XPO1 pathway,and blocking the XPO1 pathway inhibited TYLCCNV/TYLCCNB infection.We have found that the Nbb ZIP60-regulated pro-survival genes could promote virus infection,and the pro-death gene plays a contrasting role in virus infection.This study reveals that geminivirus infection activates UPR and utilizes the up-regulated molecular chaperons to promote viral infection,and then induces the nuclear export of Nbb ZIP60 to evade plant defense response,which is a distinct virulence strategy exploited by plant pathogens. | Mingzhen Zhang Buwei Cao Hui Zhang Zaifeng Fan Xueping Zhou Fangfang Li | 2023 | Science China(Life Sciences)2023，66，6： | 1 |
| 2 | Study on the Purification Effect of Phosphorus in Sewage from Sediments in Coastal Wetland of Yellow River Delta显示文摘[Objectives] This study was conducted to explore whether the coastal wetlands in the Yellow River Delta have become secondary pollution sources. [Methods] With a coastal reed wetland in the Yellow River Delta as a research object, the SMT method and DGT technology were combined to study the vertical distribution of different forms of phosphorus in the sediment and the distribution characteristics of phosphorus at the sediment-interstitial/overlying water interface of the wetland to clarify the receiving and purification capabilities of wetlands in this region. [Results] The total phosphorus content in the wetland’s water intake area, dense reed area and water outlet area increased with the depth increasing;and the wetland phosphorus accumulated in the deep layer, and the total phosphorus content in the wetland sediments was as high as 936.30 mg/kg. The research on the phosphorus forms in the wetland sediments found that the content of Ca phosphorus was the highest in the wetland sediments, followed by the content of Fe/Al-bonded phosphorus, and the exchangeable phosphorus content was the lowest. The DGT sampling technology was used to investigate the distribution characteristics of phosphorus at wetland sediment-interstitial/overlying water micro-interface. It was found that the concentrations of phosphorus in the overlying water of the water intake area, dense reed area and water outlet area were significantly higher than that in the interstitial water. The wetland pollution level in this research area was high and had an obvious cumulative effect. [Conclusions] The results show that the wetland sediments in this region have a strong ability to retain phosphorus, and can control the migration and transformation of endogenous phosphorus, and the wetland has not become a secondary pollution source. | Xueping LI Yanhui FAN | 2020 | Agricultural Biotechnology2020，9，1： | 1 |
| 3 | Interpretation of Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 7)显示文摘On March 3,2020,the National Health Commission and the National Administration of Traditional Chinese Medicine of China jointly promulgated the Notice on Printing and Distributing the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia(Trial Version 7).The content has been revised and supplemented on the basis of the Version 6,including etiological characteristics and pathological changes in lung,heart,kidney,spleen,liver,gallbladder,esophagus,stomach and intestinal mucosal epithelium.In particular,the diagnosis and treatment methods of traditional Chinese medicine are supplemented.It provides an evidence-based diagnosis and treatment protocol for the treatment and recovery of suspected and confirmed cases of novel coronavirus pneumonia with traditional Chinese medicine and Western medicine. | Jinfeng CHEN Zhongyi LEI Chaofeng LIU Hong FAN Peng LEI Xueping WU Xiaoyong YU Yanfen ZHOU Jiejun HOU | 2020 | Medicinal Plant2020，11，3： | 1 |
| 4 | Field Experiment of En- hancing Heavy Oil Recovery by Cyclic Flue Gas Injection 显示文摘 | Zhang Fengshan Fan xueping | | SPE647240，，： | 1 |
| 5 | Fluorescence Decay Lifetime of Ultrafine CdS and ZnS Particles显示文摘The fluorescence decay properties of CdS and ZnS ultrafine particles have been investigated by a single photon counting technique.We have found that the decay is dependent on the particle size,emission wavelength and colloidal sandwich structure.Shorter emission lifetimes were observed for smaller CdS particles and at shorter emission wavelength.The average emission lifetime of ZnS part in the sandwich structure of ZnS and CdS particles clearly decreased. | LI Xueping FAN Changyu ZHANG Zhenzong XIAO Xurui | 1994 | Chinese Physics Letters1994，11，2： | 0 |
| 6 | Discussion on the Selection of ACEI and ARB for the Patients with COVID-19 and Hypertension from ACE2显示文摘With the wide spread of COVID-19,some studies have confirmed that novel coronavirus enters the cell through the binding of spike protein and ACE2 protein,which has the risk of causing the virus to enter the cell to accelerate its transmission.ACEI and ARB are the key drugs for the treatment of hypertension and are widely used in clinic.They are good for ventricular and vascular remodeling in patients with hypertension,coronary heart disease and heart failure.ACEI and ARB drugs may increase the expression of ACE2 in lung tissue and increase the risk of aggravation of the disease.According to the advice of hypertension experts:for mild ordinary COVID-19 patients with hypertension,we can consider discontinuing ACEI and ARB drugs,while for severe COVID-19 patients with hypertension,ACEI and ARB drugs should be stopped immediately.During the discontinuation period,temporary replacement therapy with diuretics,dipine and vasodilatation hypotensive drugs can be considered. | Jinfeng CHEN Zhongyi LEI Chaofeng LIU Hong FAN Peng LEI Xueping WU Xiaoyong YU Yanfen ZHOU Jiejun HOU | 2020 | Medicinal Plant2020，11，4： | 0 |
| 7 | Discussion on the Prevention and Treatment of COVID-19 Causing Lung Disease and Heart Damage Based on Lei Zhongyi's Theory of Intermingled Phlegm,Blood Stasis and Toxin显示文摘Novel coronavirus infection not only damages lung function,but also causes myocardial injury,elevated myocardial enzymes and heart failure,especially for patients with basic heart diseases who develop COVID-19,the first consideration should be the protection of cardiac function.Based on the theory of intermingled phlegm,blood stasis and toxin of heart disease put forward by Master Lei Zhongyi,the dialectical treatment thinking of COVID-19 patients from the concept of damage of phlegm,blood stasis and toxin to the heart were discussed.During the diagnosis,critical stage and recovery period of COVID-19,expectorant and blood-activating agents,heat and detoxification agents can be added to promote lung and asthma,free Bizheng and remove blood stasis,calm the heart and calm the mind,and promote the recovery of cardiopulmonary functions. | Jinfeng CHEN Zhongyi LEI Chaofeng LIU Hong FAN Peng LEI Xueping WU Xiaoyong YU Yanfen ZHOU Jiejun HOU | 2020 | Medicinal Plant2020，11，6： | 0 |
| 8 | Efficacy of Danlou Tablet in the Treatment of Coronary Heart Disease with Phlegm and Blood Stasis Syndrome and Its Effects on Serum Inflammatory Factors显示文摘[Objectives] To explore the efficacy of Danlou Tablet( DLT) in the treatment of coronary heart disease( CHD) with phlegm and blood stasis syndrome and its effects on serum inflammatory factors. [Methods]One hundred and ninety-seven patients with CHD and phlegm and blood stasis syndrome in our hospital from January 2016 to January 2018 were selected and randomly divided into two groups: control group( n =98) treated with aspirin plus atorvastatin,and research group( n =99) treated with DLT and aspirin plus atorvastatin for one month. The clinical efficacy and incidence of adverse reactions were observed. Serum secretory phospholipase A2( s PLA2),lipoprotein-associated phospholipase A2( LP-PLA2),oxidized low-density lipoprotein( ox-LDL),monocyte chemoattractant protein-1( MCP-1) and World Health Organization Quality of Life( WHOQOL-100) scores were compared before and after one month of treatment. [Results] The total effective rate was93. 94% in the research group,which was higher than that in the control group( 79. 59%,P < 0. 05);the levels of serum s PLA2,LP-PLA2,ox-LDL and MCP-1 in the research group were lower than those in the control group after one month of treatment( P < 0. 05). There was no statistical significance of the difference in the total incidence of adverse reactions between the research group and the control group( P > 0. 05).After one month of treatment,WHOQOL-100 scores were higher in two groups,which were higher in the research group than that in the control group( P < 0. 05). [Conclusions]DLT can significantly reduce the level of serum inflammatory factors,improve the quality of life in patients with CHD and phlegm and blood stasis syndrome. | Jinfeng CHEN Zhongyi LEI Chaofeng LIU Hong FAN Xueping WU Xiaoyong YU Peng LEI Yong WANG | 2019 | Medicinal Plant2019，10，3： | 0 |
| 9 | The exquisite integration of ESIPT, PET and AIE for constructing fluorescent probe for Hg(II) detection and poisoning显示文摘Excessive mercury ions(Hg^(2+)) in the environment can accumulate in human body along with the food chain to cause serious physiological reactions.The fluorescence probes were considered as convenient tool with great potential for Hg^(2+) detection.Most existing probes suffer from aggregation-induced quenching(ACQ) effects and insufficient sensitivity.Herein,a novel type of fluorophore was developed by combining the aggregation-induced emission(AIE) and excited state intramolecular proton transfer(ESIPT) characteristics.Subsequently,a phenyl thioformate group with photoinduced electron transfer(PET)effect was connected to give an efficient 'turn-on' probe(HTM),which exhibited good selectivity toward Hg^(2+),short response time(30 min),coupled with extremely low detection limit(LOD=1.68 nmol/L).In addition,HTM was used successfully in real samples,cells and drug evaluation,underlying the superiority of HTM to detect Hg^(2+) in practical applications. | Xiang Cheng Shuai Huang Qian Lei Fei Chen Fan Zheng Shibo Zhong Xueyan Huang Bin Feng Xueping Feng Wenbin Zeng | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 10 | Study on Coconut Shell Activated Carbon Temperature Swing Adsorption of Benzene and Formaldehyde显示文摘Adsorption can be used to recover effectively the volatile organic gases(VOCs)in the exhaust gas from factories through using an appropriate adsorption bed.Due to form a physical or chemical bond,adsorption occurs between the porous solid medium and the liquid or gas multi component fluid mixture.The regeneration capa-city of the adsorbent is as important as the adsorption capacity and it determines the economics of the adsorption system.The regeneration of adsorbent can be realized through changing the pressure or temperature of the system.Here,activated carbon samples from coconut shell were prepared and characterized.Benzene or formal-dehyde in the mixed air was used as the adsorption object,and the adsorption experiment was carried out in a U-shaped bed.Discussed how adsorption was affected by activated carbon type,adsorbate and temperature.The results show that oxidation modifed activated carbon can increase the adsorption effect of form aldehyde,but will reduce the ad sorption effect of benzene,because their ad sorption mechanism is different.At 30℃,the saturated adsorption apacity of AC-0 for benzene is 437.0 mg/g.and that of AC-1 for formaldehyde is 670.5 mg/g.In the experimental range,it is found that the adsorption capacity increases with the decrease of temperature,and their changes are very consistent with the ftted ExpDecay1 function. | Zhiguang Yang Gaojun Yan Xueping Liu Zhengyuan Feng Xinfeng Zhu Yanli Mao Songtao Chen Zhisheng Yu Ruimei Fan Linlin Shan | 2022 | Journal of Renewable Materials2022，10，12： | 0 |
| 11 | Data Fusion about Serviceability Reliability Prediction for the Long-Span Bridge Girder Based on MBDLM and Gaussian Copula Technique显示文摘This article presented a new data fusion approach for reasonably predicting dynamic serviceability reliability of the long-span bridge girder.Firstly,multivariate Bayesian dynamic linear model(MBDLM)considering dynamic correlation among the multiple variables is provided to predict dynamic extreme deflections;secondly,with the proposed MBDLM,the dynamic correlation coefficients between any two performance functions can be predicted;finally,based on MBDLM and Gaussian copula technique,a new data fusion method is given to predict the serviceability reliability of the long-span bridge girder,and the monitoring extreme deflection data from an actual bridge is provided to illustrated the feasibility and application of the proposed method. | Xueping Fan Guanghong Yang Zhipeng Shang Xiaoxiong Zhao Yuefei Liu | 2021 | Structural Durability & Health Monitoring2021，15，1： | 0 |
| 12 | Identification of terrigenous and autochthonous organic carbon in sediment cores from cascade reservoirs in the upper stream of Pearl River and Wujiang River,southwest China:lignin phenol as a tracer显示文摘Organic carbon(OC)source attribution for cascade reservoir sediments has been identified as a critical gap in understanding the effective carbon sink of inland waters.In this study,nine sediment cores were collected from cascade reservoirs in the Wujiang and Pearl Rivers.We analyzed lignin phenol(Λ8),total organic carbon(TOC)content,and stable carbon isotopic composition(δC)of the sediments,focusing on the changes of terrigenous OC,and the variation of OC source in cascade reservoir sediments after damming.Our results showed that theΣ8 and TOC contents decreased from upstream to downstream reservoirs,indicating the significant interception of terrigenous OC by cascade damming.Additionally,theΛ8 content in the Pearl River reservoir sediments was much higher than that in the Wujiang River.From the three-end-member mixing model,we estimated that OC in reservoir sediments mainly comes from soil and plankton.After damming,the proportion of plankton OC in TOC slightly increased in seasonal and annual regulation reservoirs due to the limnetic evolution of the reservoir.These findings suggest that the cascade damming increases the interception capacity of the river to terrigenous OC and nutrients,and that slowing of water velocity caused by damming affected primary productivity and fluvial carbon cycling. | Li Gao Xin Lin Jun Fan Ming Yang Xueping Chen FushunWang Jing Ma | 2022 | Acta Geochimica2022，41，5： | 0 |
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