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| 1 | Tiller Bud Formation Regulators MOC1 and MOC3 Cooperatively Promote Tiller Bud Outgrowth by Activating F0N1 Expression in Rice显示文摘Tillering in rice is one of the most important agronomic traits.Rice tiller development can be divided into two main processes: the formation of the axillary bud and its subsequent outgrowth.Several genes critical for bud formation in rice have been identified by genetic studies;however,their molecular functions and relationships are still largely unknown.Here,we report that MONOCULM 1 (MOC1) and MONOCULM 3/ TILLERS ABSENT 1/STERILE AND REDUCED TILLERING 1 (MOC3/TAB1/SRT1),two vital regulators for tiller formation in rice,physically interact to regulate tiller bud outgrowth through upregulating the expression of FLORAL ORGAN NUMBER 1 (FON1),the homolog of CLAVATA1 in rice.We found that M0C3 is able to directly bind the promoter ofFONI and subsequently activate FON1 expression.MOC1 functions as a coactivator of MOC3,whereas it could not directly bind the FON1 promoter,and further activated FON1 expression in the presence of MOC3.Accordingly,FON1 is highly expressed at axillary meristems and shows remarkably decreased expression levels in mod and moc3 mutants.Loss-of-function mutants of FON1 exhibit normal bud formation but defective bud outgrowth and reduced tiller number.Collectively,these results shed light on a joint transcriptional regulatory mechanim by MOC1 and MOC3,and establish a new framework for the control of tiller bud formation and outgrowth. | Gaoneng Shao Zefu Lu Jinsong Xiong Bing Wang Yanhui Jing Xiangbing Meng Guifu Liu Haiyan Ma Yan Liang Fan Chen Yonghong Wang Jiayang Li Hong Yu | 2019 | Molecular Plant2019，12，8： | 15 |
| 2 | Layered double hydroxide(LDH) for multi-functionalized corrosion protection of metals: A review显示文摘Layered double hydroxide(LDH) has been widely developed in the field of corrosion and protection in recent years based on its unique characteristics including anion capacity, anion exchange ability, structure memory effect, and barrier resistance. This paper comprehensively reviews recent work on the preparations, properties of LDH in the forms of powder and film and their applications in different environments in corrosion and protection. Some novel perspectives are also proposed at the end of the review for future research in corrosion and protection field. | Yanhui Cao Dajiang Zheng Fan Zhang Jinshan Pan Changjian Lin | 2022 | Journal of Materials Science & Technology2022，，7： | 9 |
| 3 | Origins and pathways of the subsurface and intermediate water masses of the Indonesian Throughflow derived from historical and Argo data显示文摘On the basis of Argo data and historic temperature/salinity data from the World Ocean Database 2001(WOD01),origins and spreading pathways of the subsurface and intermediate water masses in the Indonesian Throughflow(ITF)region were discussed by analyzing distributions of salinity on representative isopycnal layers.Results were shown that,subsurface water mostly comes from the North Pacific Ocean while the intermediate water originates from both the North and South Pacific Ocean,even possibly from the Indian Ocean.Spreading through the Sulawesi Sea,the Makassar Strait,and the Flores Sea,the North Pacific subsurface water and the North Pacific Intermediate water dominate the western part of the Indonesian Archipelago.Furthermore as the depth increases,the features of the North Pacific sourced water masses become more obvious.In the eastern part of the waters,high salinity South Pacific subsurface water is blocked by a strong salinity front between Halmahera and New Guinea.Intermediate water in the eastern interior region owns salinity higher than the North Pacific intermediate water and the antarctic intermediate water(AAIW),possibly coming from the vertical mixing between subsurface water and the AAIW from the Pacific Ocean,and possibly coming from the northward extending of the AAIW from the Indian Ocean as well. | ZHANG Yanhui YU Xiaolin WANG Fan | 2008 | Acta Oceanologica Sinica2008，27，4： | 4 |
| 4 | Fargeted elimination of mutant mitochondria DNA in MELAS-iPSCs by mitoTALENs显示文摘 | Yi Yang Han Wu Xiangjin Kang Yanhui Liang Ting Lan Tianjie Li Tao Tan Jiangyun Peng Quanjun Zhang Geng An Yali Liu Qian Yu Zhenglai Ma Ying Lian Boon Seng Soh Qingfeng Chen Ping Liu Yaoyong Chen Xiaofang Sun Rong Li Xiumei Zhen Yang Yu Xiaoping Li Yong Fan | 2018 | Protein & Cell2018，9，3： | 4 |
| 5 | Lacrimal sac diverticulum presenting as a lower eyelid mass with a secreting fistula显示文摘 | Zhang Chengyue Wu Qian Yu Jifeng Cui Yanhui Cao Wenhong Fan Yunwei Yu Gang | 2014 | Chinese Medical Journal2014，，18： | 4 |
| 6 | Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia显示文摘Schizophrenia is a common disorder with a high heritability, but its genetic architecture is still elusive.We implemented whole-genome sequencing(WGS) analysis of 8 families with monozygotic(MZ) twin pairs discordant for schizophrenia to assess potential association of de novo mutations(DNMs) or inherited variants with susceptibility to schizophrenia. Eight non-synonymous DNMs(including one splicing site) were identified and shared by twins, which were either located in previously reported schizophrenia risk genes(p.V24689 I mutation in TTN, p.S2506 T mutation in GCN1L1, IVS3+1G > T in DOCK1) or had a benign to damaging effect according to in silico prediction analysis. By searching the inherited rare damaging or loss-of-function(LOF) variants and common susceptible alleles from three classes of schizophrenia candidate genes, we were able to distill genetic alterations in several schizophrenia risk genes, including GAD1, PLXNA2, RELN and FEZ1. Four inherited copy number variations(CNVs; including a large deletion at 16p13.11) implicated for schizophrenia were identified in four families, respectively. Most of families carried both missense DNMs and inherited risk variants, which might suggest that DNMs, inherited rare damaging variants and common risk alleles together conferred to schizophrenia susceptibility. Our results support that schizophrenia is caused by a combination of multiple genetic factors, with each DNM/variant showing a relatively small effect size. | Jinsong Tang Yu Fan Hong Li Qun Xiang Deng-Feng Zhang Zongchang Li Ying He Yanhui Liao Ya Wang Fan He Fengyu Zhang Yin Yao Shugart Chunyu Liu Yanqing Tang Raymond C.K.Chan Chuan-Yue Wang Yong-Gang Yao Xiaogang Chen | 2017 | Journal of Genetics and Genomics2017，44，6： | 4 |
| 7 | Performance improvement of optimization solutions by POD-based data mining显示文摘The performance of an optimized aerodynamic shape is further improved by a second-step optimization using the design knowledge discovered by a data mining technique based on Proper Orthogonal Decomposition(POD) in the present study. Data generated in the first-step optimization by using evolution algorithms is saved as the source data, among which the superior data with improved objectives and maintained constraints is chosen. Only the geometry components of the superior data are picked out and used for constructing the snapshots of POD. Geometry characteristics of the superior data illustrated by POD bases are the design knowledge, by which the second-step optimization can be rapidly achieved. The optimization methods are demonstrated by redesigning a transonic compressor rotor blade, NASA Rotor 37, in the study to maximize the peak adiabatic efficiency, while maintaining the total pressure ratio and mass flow rate.Firstly, the blade is redesigned by using a particle swarm optimization method, and the adiabatic efficiency is increased by 1.29%. Then, the second-step optimization is performed by using the design knowledge, and a 0.25% gain on the adiabatic efficiency is obtained. The results are presented and addressed in detail, demonstrating that geometry variations significantly change the pattern and strength of the shock wave in the blade passage. The former reduces the separation loss,while the latter reduces the shock loss, and both favor an increase of the adiabatic efficiency. | Yanhui DUAN Wenhua WU Peihong ZHANG Fulin TONG Zhaolin FAN Guiyu ZHOU Jiaqi LUO | 2019 | Chinese Journal of Aeronautics2019，32，4： | 3 |
| 8 | Achieving a sub-10 nm nanopore array in silicon by metal-assisted chemical etching and machine learning显示文摘Solid-state nanopores with controllable pore size and morphology have huge application potential.However,it has been very challenging to process sub-10 nm silicon nanopore arrays with high efficiency and high quality at low cost.In this study,a method combining metal-assisted chemical etching and machine learning is proposed to fabricate sub-10 nm nanopore arrays on silicon wafers with various dopant types and concentrations.Through a SVM algorithm,the relationship between the nanopore structures and the fabrication conditions,including the etching solution,etching time,dopant type,and concentration,was modeled and experimentally verified.Based on this,a processing parameter window for generating regular nanopore arrays on silicon wafers with variable doping types and concentrations was obtained.The proposed machine-learning-assisted etching method will provide a feasible and economical way to process high-quality silicon nanopores,nanostructures,and devices. | Yun Chen Yanhui Chen Junyu Long Dachuang Shi Xin Chen Maoxiang Hou Jian Gao Huilong Liu Yunbo He Bi Fan Ching-Ping Wong Ni Zhao | 2021 | International Journal of Extreme Manufacturing2021，3，3： | 2 |
| 9 | The entropy characters of point mutation显示文摘The biological diversity, which depends on the genetic material DNA, is the foundation for a species to survive and evolve. The entropy is the best measurement of biological diversity. Based on the sin-gle-parameter and the two-parameter models, here we established some differential equations about the point mutation of a DNA sequence with finite length, as well as some functions describing the processes of the variation in quantities of 4 kinds of bases (A, T, G and C) in the DNA sequence. At the molecular level, we discussed the entropy characteristics of point mutation. The results proved that a species maintained its entropy and evolved in the direction of the increasing biological diversity. In order to testify the theoretical results, we did a series of computer simulations of random point muta- tion in Matlab environment. The results were well consistent with the theoretical researches. | MA GuoJi LIANG LiJing FAN YanHui WANG WenJuan DAI JiaQing YUAN ZhiFa | 2008 | Chinese Science Bulletin2008，53，19： | 2 |
| 10 | A fluorimetric method for the determination of trace pentachlorophenol, based on its inhibitory effect on the redox reaction between the improved Fenton reagent and rhodamine B 显示文摘 | GUO HUIQIN FAN JING GUO YANHUI | 2007 | Luminescence2007，22，： | 1 |
| 11 | Rapid decolorization of azo dye methyl orange in aqueous solution by nanoscale zerova- lent iron particles显示文摘 | Fan Jing Guo Yanhui Wang Jianji | 2009 | Journal of Hazardous Materials2009，166，23： | 1 |
| 12 | Tuning redox activity through delithiation induced protective layer and Fe-O coordination for Li-rich cathode with improved voltage and cycle performance显示文摘Li-rich layered transition metal oxides are one of the most promising cathode materials for their high energy density.However,the cathodes usually suffer from severe potential dropping and capacity fading during cycling,which are associated with the surface oxygen release and accompanied by cation densification and structural collapse.Herein,an integrative approach of simultaneous constructing uniform 3d Fe-ion doping in the transition metal layer and Li-rich Li_(5)FeO_(4) shell to grab the oxygen and prevent interfacial side reactions is proposed.The introduction of Fe induces higher redox potential and stronger 3 d Fe-O_(2)p covalent bond,triggering reversible anionic redox via a reductive coupling mechanism.And the delithiated product of Li-rich Li_(5)FeO_(4) not only acts as a protective layer alleviating the side reactions but also enhances the surface kinetic property.With the benefit of promoted reversibility of oxygen redox and enhanced surface stability,the cathode exhibits high reversible capacity and superior cycle performance.Density function theory calculation indicates that the O_(2)p non-bonding state in the cathode incorporated with Fe sits at a lower energy band,resulting in higher energy storage voltage and improved oxygen stability.Consequently,the modified cathode exhibits a discharge specific capacity of 307 m A h g^(-1)(1 C=250 m A g^(-1)),coulombic efficiency of 82.09%in the initial cycle at 0.1 C and 88.34%capacity retention after 100 cycles at 1 C.The work illustrates a strategy that could simultaneously enhance oxygen redox reversibility and interface stability by constructing lattice bond coordination and delithiation induced protective layer to develop Li-rich materials with high reversible capacity and long lifespan. | Kanghui Hu Li Ren Weifeng Fan Bing Zhang Meihua Zuo Yanhui Zhang Genpin Lv Huiyuan Xu Wei Xiang Xiaodong Guo | 2022 | Journal of Energy Chemistry2022，31，8： | 1 |
| 13 | Rapid decolorization of azo dye methyl orange in aqueous solution by nanoscale zerovalent iron particles显示文摘 | Fan Jing Guo Yanhui Wang Jianji | 2009 | Journal of Hazardous Materials2009，166，： | 1 |
| 14 | Study on the Purification Effect of Phosphorus in Sewage from Sediments in Coastal Wetland of Yellow River Delta显示文摘[Objectives] This study was conducted to explore whether the coastal wetlands in the Yellow River Delta have become secondary pollution sources. [Methods] With a coastal reed wetland in the Yellow River Delta as a research object, the SMT method and DGT technology were combined to study the vertical distribution of different forms of phosphorus in the sediment and the distribution characteristics of phosphorus at the sediment-interstitial/overlying water interface of the wetland to clarify the receiving and purification capabilities of wetlands in this region. [Results] The total phosphorus content in the wetland’s water intake area, dense reed area and water outlet area increased with the depth increasing;and the wetland phosphorus accumulated in the deep layer, and the total phosphorus content in the wetland sediments was as high as 936.30 mg/kg. The research on the phosphorus forms in the wetland sediments found that the content of Ca phosphorus was the highest in the wetland sediments, followed by the content of Fe/Al-bonded phosphorus, and the exchangeable phosphorus content was the lowest. The DGT sampling technology was used to investigate the distribution characteristics of phosphorus at wetland sediment-interstitial/overlying water micro-interface. It was found that the concentrations of phosphorus in the overlying water of the water intake area, dense reed area and water outlet area were significantly higher than that in the interstitial water. The wetland pollution level in this research area was high and had an obvious cumulative effect. [Conclusions] The results show that the wetland sediments in this region have a strong ability to retain phosphorus, and can control the migration and transformation of endogenous phosphorus, and the wetland has not become a secondary pollution source. | Xueping LI Yanhui FAN | 2020 | Agricultural Biotechnology2020，9，1： | 1 |
| 15 | Liquid chromatography–tandem mass spectrometric method for the analysis of fluconazole and evaluation of the impact of phenolic compounds on the concentration of fluconazole in Candida albicans显示文摘 | Shujuan Sun Hongxiang Lou Yanhui Gao Peihong Fan Bin Ma Weiying Ge Xiaoning Wang | 2003 | Journal of Pharmaceutical and Biomedical Analysis2003，，5： | 1 |
| 16 | Rapid decolorization of azo dye methyl orange in aqueous solution by nanoscale zerovalent iron particles显示文摘 | Fan Jing Guo Yanhui Wang Jianji | 2009 | Journal of Hazardous Materials2009，166，23： | 1 |
| 17 | Influences of flexible defect on the interplay of supercoiling and knotting of circular DNA显示文摘Knots are discovered in biophysical systems,such as DNA and proteins.Knotted portions in knotted DNA are significantly bent and their corresponding bending angles are comparable with or larger than the sharp bending angle resulting in flexible defects.The role of flexible defects in the interplay of supercoiling and knotting of circular DNA were predicted by a Monte Carlo simulation.In knotted DNA with a particular knot type,a flexible defect noticeably enhances the supercoiling of the knotted DNA and the decreasing excitation energy makes the knotted portion more compact.A reduction in twist rigidity and unwinding of flexible defects are incorporated into the numerical simulations,so that interplay of supercoiling and knotting of circular DNA is studied under torsional conditions.Increasing unwinding not only results in a wider linking number distribution,but also leads to a drift of the distribution to lower values.A flexible defect has obvious effects on knotting probability.The summation of equilibrium distribution probability for nontrivial knotted DNA with different contour length does not change with excitation energy monotonically and has a maximum at an intermediate value of excitation energy around 5 kBT.In the phase space of knot length and gyration radius of knotted DNA,knot length does not anticorrelate with its gyration radius,which is attributed to the flexible defect in the knotted portion,which leads to the release of bending energy and inhibited the competition between entropy and bending energy. | Caiyun Xiong Xiaolin Nie Yixue Peng Xun Zhou Yangtao Fan Hu Chen Yanhui Liu | 2021 | Communications in Theoretical Physics2021，73，7： | 0 |
| 18 | ENO1 expression and Erk phosphorylation in PDAC and their effects on tumor cell apoptosis in a hypoxic microenvironment显示文摘Objective: Hypoxia is an important feature of pancreatic ductal adenocarcinoma(PDAC). Previously, we found that hypoxia promotes ENO1 expression and PDAC invasion. However, the underlying molecular mechanism was remains unclear.Methods: The relationship between ENO1 expression and clinicopathological characteristics was analyzed in 84 patients with PADC. The effects of CoCl2-induced hypoxia and ENO1 downregulation on the apoptosis, invasion, and proliferation of PDAC cells were evaluated in vitro and in vivo. Hypoxia-and ENO1-induced gene expression was analyzed by transcriptomic sequencing.Results: The prognosis of PDAC with high ENO1 expression was poor(P < 0.05). High ENO1 expression was closely associated with histological differentiation and tumor invasion in 84 PDAC cases(P < 0.05). Hypoxia increased ENO1 expression in PDAC and promoted its migration and invasion. Apoptotic cells and the apoptosis marker caspase-3 in the CoCl_(2)-treated ENO1-sh group were significantly elevated(P < 0.05). Transcriptomic sequencing indicated that CoCl_(2)-induced PDAC cells initiated MAPK signaling. Under hypoxic conditions, PDAC cells upregulated ENO1 expression, thereby accelerating ERK phosphorylation and inhibiting apoptosis(P < 0.05). Consistent results were also observed in a PDAC-bearing mouse hindlimb ischemia model.Conclusions: Hypoxia-induced ENO1 expression promotes ERK phosphorylation and inhibits apoptosis, thus leading to PDAC survival and invasion. These results suggest that ENO1 is a potential therapeutic target for PDAC. | Huizhi Sun Jing Mo Runfen Cheng Fan Li Yue Li Yuhong Guo Yanlei Li Yanhui Zhang Xiaoyu Bai Yalei Wang Xueyi Dong Danfang Zhang Jihui Hao | 2022 | Cancer Biology & Medicine2022，19，11： | 0 |
| 19 | The rates and patterns of insertions, deletions and substitutions in mouse and rat inferred from introns显示文摘The rates and patterns of InDel (insertions and deletions) and substitution in rodent (mouse and rat) have been studied. The result reveals that deletions occur more frequently than insertions, and single nucleotide insertion and deletion are the most frequent in both mouse and rat. The frequencies of both deletions and insertions decrease rapidly with increasing InDels length, and the size distributions of both insertions and deletions can be described well by power-law. There are more AT→GC than GC→ AT substitutions in the introns of rat. However, there are more GC→AT than AT→GC substitutions in the introns in mouse. The deletion bias found in introns in mouse and rat supports the prediction that in- tron insertions are more deleterious than deletions because of reduced transcription and splicing effi- ciency. The patterns of substitution suggest that both composition and GC content are not equilibrium in the introns in rodents. | FAN YanHui SHI Qi CHEN JinFeng WANG WenJuan PANG HongXia TANG JiaoWei TAO ShiHeng | 2008 | Chinese Science Bulletin2008，53，18： | 0 |
| 20 | The plasmodesmata-associated β-1,3-glucanase gene GhPdBG regulates fiber development in cotton显示文摘Trichomes are specialized structures that originate from epidermal cells of organs in higher plants.The cotton fiber is a unique single-celled trichome that elongates from the seed coat epidermis.Cotton(Gossypium hirsutum)fibers and trichomes are models for cell differentiation.In an attempt to elucidate the intercellular factors that regulate fiber and trichome cell development,we identified a plasmodesmal β-1,3-glucanase gene(designated GhPdBG)controlling the opening and closing of plasmodesmata in cotton fibers.Structural and evolutionary analysis showed haplotypic variation in the promoter region of the GhPdBG gene among 352 cotton accessions,but high conservation in the coding region.GhPdBG was expressed predominantly in cotton fibers and localized to plasmodesmata(PD).Expression patterns of PdBG that corresponded to PD permeability were apparent during fiber development in G.hirsutum and G.barbadense.The PdBG-mediated opening-closure of PD appears to be involved in fiber development and may account for the contrasting fiber traits of these two species.Ectopic expression of GhPdBG revealed that it functions in regulating fiber and trichome length and/or density by modulating plasmodesmatal permeability.This finding suggests that plasmodesmal targeting of GhPdBG,as a switch of intercellular channels,regulates single-celled fiber and trichome development in cotton. | Yijie Fan Shuangshuang Lin Yanhui Lyu Haihong Shang Youlu Yuan Zhengmin Tang Chengzhi Jiao Aiyun Chen Piyi Xing Li Zhang Yuxiao Sun Haixia Guo Tongtong Li Zhonghai Ren Fanchang Zeng | 2023 | The Crop Journal2023，11，6： | 0 |
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