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| 1 | Plasma membrane proteome analysis of the early effect of alcohol on liver: implications for alcoholic liver disease显示文摘在人,酒精的在消费上能导致严肃的肝疾病。在肝疾病上检验酒精的早效果,老鼠被给足够的乙醇开发肝肝硬化。在纤维变性的发作前的老鼠在这个工作被学习。肝的血浆膜(下午) 被提取由两次蔗糖密度坡度 centrifugation。从对待乙醇的老鼠和控制的下午的 proteome 侧面为相对、绝对的 quantitation (iTRAQ ) 用二维的胶化电气泳动(2-DE ) 和等压的标签被分析技术。乙醇处理改变了 15 不同的肝蛋白质的数量:他们中的 10 个被 2-DE 检测并且 5 由 iTRAQ。角质素 8 被两个方法检测。这些差别的基因本体论分析检测了显示的蛋白质他们的那个大多数涉及象有约束力的活动那样的重要房间函数(包括离子, DNA, ATP 绑定,等等) ,房间结构,或酶活动。在这些之中, annexin A2,角质素 8,和角质素 18 进一步用西方的污点分析被验证, annexin A2 被 immunohistochemistry 验证。我们的结果建议酒精有潜力由在 PM 改变几相关蛋白质的表示层次影响房间结构,粘附和酶活动。就我们的知识而言,这是第一次在肝下午 proteome 上学习酒精的效果,它可能对理解导致白酒的肝疾病的可能的机制有用。 | Lijun Zhang Xiaofang Jia Yanling Feng Xia Peng Zhiyong Zhang Wenjiang Zhou Zhanqing Zhang Fang Ma Xiaohui Liu Ye Zheng Pengyuan Yang Zhenghong Yuan | 2011 | Acta Biochimica et Biophysica Sinica2011，43，1： | 8 |
| 2 | Effect of rolling strain on microstructure and tensile properties of dual-phase Mg-8Li-3Al-2Zn-0.5Y alloy显示文摘This study was conducted to discuss the effect of rolling strain on microstructure and tensile properties of dual-phase Mg-8Li-3Al-2Zn-0.5 Y(wt%) alloy, which was prepared by casting, and then homogenized and rolled at 200℃. The rolling process was conducted with 10% reduction per pass and five different accumulated strains, varying from 10% to 70%. The results indicate that the as-cast and as-rolled Mg-8Li-3Al-2Zn-0.5Y alloys are composed of α-Mg, β-Li, AlLi and Al_2Y phases. After rolling process,anisotropic microstructure was observed. a-Mg phase got elongated in both rolling direction and transverse direction with the addition of rolling strain. Consequently, the strength of the alloy in both directions was notably improved whereas the elongation declined, mainly caused by strain hardening and dispersion strengthening. The tensile properties of the as-rolled alloys in the RD, no matter the YS, UTS or the elongation, are higher than those of the TD due to their larger deformation strain and significant anisotropy in the hcp α-Mg phase. In addition, the fracture and strengthening mechanism of the tested alloys were also investigated systematically. | Wencai Liu Shi Feng Zhongquan Li Jiong Zhao Guohua Wu Xianfei Wang Lv Xiao Wenjiang Ding | 2018 | Journal of Materials Science & Technology2018，34，12： | 6 |
| 3 | A New model to forecast fishing ground of Scomber japonicus in the Yellow Sea and East China Sea显示文摘The pelagic species is closely related to the marine environmental factors, and establishment of forecasting model of fishing ground with high accuracy is an important content for pelagic fishery. The chub mackerel(Scomber japonicus) in the Yellow Sea and East China Sea is an important fishing target for Chinese lighting purse seine fishery. Based on the fishery data from China's mainland large-type lighting purse seine fishery for chub mackerel during the period of 2003 to 2010 and the environmental data including sea surface temperature(SST), gradient of the sea surface temperature(GSST), sea surface height(SSH) and geostrophic velocity(GV), we attempt to establish one new forecasting model of fishing ground based on boosted regression trees. In this study, the fishing areas with fishing effort is considered as one fishing ground, and the areas with no fishing ground are randomly selected from a background field, in which the fishing areas have no records in the logbooks. The performance of the forecasting model of fishing ground is evaluated with the testing data from the actual fishing data in 2011. The results show that the forecasting model of fishing ground has a high prediction performance, and the area under receiver operating curve(AUC) attains 0.897. The predicted fishing grounds are coincided with the actual fishing locations in 2011, and the movement route is also the same as the shift of fishing vessels, which indicates that this forecasting model based on the boosted regression trees can be used to effectively forecast the fishing ground of chub mackerel in the Yellow Sea and East China Sea. | GAO Feng CHEN Xinjun GUAN Wenjiang LI Gang | 2016 | Acta Oceanologica Sinica2016，35，4： | 5 |
| 4 | Digital high-efficiency print forming method and device for multi-material casting molds显示文摘Sand mold 3D printing technology based on the principle of droplet ejection has undergone rapid development in recent years and has elicited increasing attention from engineers and technicians.However,current sand mold 3D printing technology exhibits several problems,such as single-material printing molds,low manufacturing efficiency,and necessary post-process drying and heating for the manufacture of sand molds.This study proposes a novel high-efficiency print forming method and device for multi-material casting molds.The proposed method is specifically related to the integrated forming of two-way coating and printing and the shortflow manufacture of roller compaction and layered heating.These processes can realize the high-efficiency print forming of high-performance sand molds.Experimental results demonstrate that the efficiency of sand mold fabrication can be increased by 200%using the proposed two-way coating and printing method.The integrated forming method for layered heating and roller compaction presented in this study effectively shortens the manufacturing process for 3D-printed sand molds,increases sand mold strength by 63.8%,and reduces resin usage by approximately 30%.The manufacture of multi-material casting molds is demonstrated on typical wheeled cast-iron parts.This research provides theoretical guidance for the engineering application of sand mold 3D printing. | Zhongde SHAN Zhi GUO Dong DU Feng LIU Wenjiang LI | 2020 | Frontiers of Mechanical Engineering2020，15，2： | 5 |
| 5 | Effects of Zr,Ti and Sc additions on the microstructure and mechanical properties of Al-0.4Cu-0.14Si-0.05Mg-0.2Fe alloys显示文摘The evolution of microstructure and mechanical properties of Al-0.4 Cu-0.14 Si-0.05 Mg-0.2 Fe(wt.%)alloys, micro-alloyed with Zr, Ti and Sc, were investigated. The addition of 0.2%Zr to base alloy accelerates the precipitation of Si-rich nano-phase in α-Al matrix, which plays an important role in improving the mechanical properties of an alloy. The tensile strength increases from 102 MPa for the base alloy to 113 MPa for the Zr-modified alloy. Adding 0.2%Zr + 0.2%Ti to base alloy effectively refines a-Al grain size and accelerates the precipitation of Si and Cu elements, leading to heavy segregation at grain boundary.By further adding 0.2%Sc to Zr + Ti modified alloy, the segregation of Si and Cu elements is suppressed and more Si and Cu precipitates appeared in α-Al matrix. Accompanied with the formation of coherent Al_3Sc phase, the tensile strength increases from 108 MPa for the Zr + Ti modified alloy to 152 MPa for the Sc-modified alloy. Due to excellent thermal stability of Al_3Sc phase, the Sc-modified alloy exhibits obvious precipitation hardening behavior at 350℃, and the tensile strength increases to 203 MPa after holding at 350 ℃ for 200 h. | Jian Feng Bing Ye Lijie Zuo Ruijuan Qi Qudong Wang Haiyan Jiang Rong Huang Wenjiang Ding Jie Yao Chuntao Wang | 2018 | Journal of Materials Science & Technology2018，34，12： | 3 |
| 6 | Microstructure, tensile properties and creep behavior of Al-12Si-3.5Cu-2Ni-0.8Mg alloy produced by different casting technologies显示文摘The relationship between the as-cast microstructure and mechanical properties of the Al-12 Si-3.5 Cu-2 Ni-0.8 Mg alloys produced by permanent mold casting(PMC) and high pressure die casting(HPDC)is investigated. The alloys in both PMC and HPDC consist of Al, Si, Al_5 Cu_2 Mg_8 Si_6, Al_3 Cu Ni, and Al_7 Cu_4 Ni phase. However, the microstructure of the HPDC alloy is significantly refined. Compared to the PMC alloy,the ultimate tensile strength of the HPDC alloy is significantly increased from 244 MPa to 310 MPa, while the elongation shows a reverse trend at room temperature. At low stress and temperature range, slight variations of stress exponent and activation energy indicate that the minimum creep rate is controlled by the grain boundary creep. Then the minimum creep rate is higher for the specimen with the smaller grain size, where grain boundary creep is the dominant creep mechanism. At high stress region, the stress exponent for the PMC alloy and HPDC alloy is 5.18 and 3.07, respectively. The different stress exponents and activation energies measured at high stress and high temperature range indicates that the creep mechanism varies with the casting technologies. | Lijie Zuo Bing Ye Jian Feng Xiangyang Kong Haiyan Jiang Wenjiang Ding | 2018 | Journal of Materials Science & Technology2018，34，7： | 3 |
| 7 | Linkages between the biomass of Scomber japonicus and net primary production in the southern East China Sea显示文摘Fish biomass is a critical component of fishery stock assessment and management and it is often estimated from ocean primary production(OPP). However, the relationship between the biomass of a fish stock and OPP is always complicated due to a variety of trophic controls in the ecosystem. In this paper, we examine the quantitative relationship between the biomass of chub mackerel(Scomber japonicus) and net primary production(NPP) in the southern East China Sea(SECS), using catch and effort data from the Chinese mainland large light-purse seine fishery logbook and NPP derived from remote sensing. We further discuss the mechanisms of trophic control in regulating this relationship. The results show a significant non-linear relationship exists between standardized CPUE(Catch-Per-Unit-Effort) and NPP(P<0.05). This relationship can be described by a convex parabolic curve, where the biomass of chub mackerel increases with NPP to a maximum and then decreases when the NPP exceeds this point. The results imply that the ecosystem in the SECS is subject to complex trophic controls. We speculate that the change in abundance of key species at intermediate trophic levels and/or interspecific competition might contribute to this complex relationship. | GUAN Wenjiang CHEN Xinjun GAO Feng LI Gang | 2014 | Acta Oceanologica Sinica2014，33，10： | 2 |
| 8 | Application of Drucker–Prager plasticity to predict fracture in rectangular cup drawing of AZ31 alloy sheet显示文摘 | Fenghua Wang Jie Dong Miaolin Feng Xingwei Zheng Wenjiang Ding | 2011 | Materials Science & Engineering A2011，，： | 1 |
| 9 | XiaoMu: an AI-driven assistant for MOOCs显示文摘Nowadays, massive open online courses(MOOCs), are attracting widespread interest as an alternative education model. Several MOOCs platforms, such as Coursera, edX,and Udacity have been built and they provide low-cost opportunities for anyone who needs to access a massive number of courses from the worldwide top universities. However, the learning completion rate of the learners via MOOCs is extremely low compared with that in real classroom learning.Thus, this study builds a system, called XiaoMu, to design intelligent intervention strategies for the learning process of learners and improve the learning efficiency through automatic analysis of courses and learners. We deployed our system on the website1), which is one of the largest MOOCs in China. | Zhengyang SONG Jie TANG Tracy Xiao LIU Wenjiang ZHENG Lili WU Wenzheng FENG Jing ZHANG | 2021 | Science China(Information Sciences)2021，64，6： | 1 |
| 10 | Rational Design of Graphene Surface Chemistry for High- Performance Rubber/Graphene Composites显示文摘 | Tang Zhenghai Zhang Liqun Feng Wenjiang | 2014 | Macromolecules2014，，47： | 1 |
| 11 | Applications of representation method for DNA sequences based on symbolic dynamics显示文摘 | Wang Shiyuan Tian Fengchun Feng Wenjiang | | 0，，： | 1 |
| 12 | Reduced-complexity MPA decoder based on multi-level dynamic input thresholds显示文摘As a key technology of the fifth generation(5G) wireless communications, sparse code multiple access(SCMA) system has quite high frequency utilization, but its message passing algorithm(MPA) decoder still has high time complexity. By the aid of the proposed multi-level dynamic threshold, the complexity of the MPA decoding can be greatly reduced with little error performance loss. In order to reduce a great deal of insignificant computational amounts of message update, we compare the multi-level symbols probability products with optimized multi-level thresholds step by step before they are used for message update calculation. The dynamic threshold configuration refers to the three factors: the level of input symbol probabilities, signal noise ratio(SNR) and the number of iterations. Especially, in the joint iterative MPA-Turbo decoding procedure, since most encoded bits have good convergence, the input thresholds can avoid more unnecessary computational overhead of message update and reduce the decoding time more significantly. The simulation results show that the proposed multi-level dynamic thresholds considerably reduce the decoding delay in both additive white Gaussian noise(AWGN) channel and frequency selective fading channel. | Tan Wei Zhao Xingcheng Liu Yuxiang Gu Shaoxiang Feng Wenjiang | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，1： | 0 |
| 13 | BTN2A2 protein ameliorates collagen-induced arthritis in mice显示文摘Rheumatoid arthritis(RA)is an autoimmune disorder characterized by persistent inflammatory responses in target tissues and organs,resulting in the destruction of joints.Collagen type II(CII)-induced arthritis(CIA)is the most used animal model for human RA.Although BTN2A2 protein has been previously shown to inhibit T cell functions in vitro,its effect on autoimmune arthritis has not been reported.In this study,we investigate the ability of a recombinant BTN2A2-IgG2a Fc(BTN2A2-Ig)fusion protein to treat CIA.We show here that administration of BTN2A2-Ig attenuates established CIA,as compared with control Ig protein treatment. | He Xueping Hu Rong Luo Peng Gao Jie Yang Wenjiang Li Jiaju Huang Youjiao Han Feng Lai Laijun Su Min | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 14 | Simulation Study on the Interannual Variation of the Transport and Distribution of Chub Mackerel (Scomber japonicus) Larvae and Juveniles Using Individual-Based Model显示文摘An individual-based model of Scomber japonicus in the East China Sea(ECS)was developed to simulate the effects of physical environment on the transport and distribution of eggs,larvae and juveniles of S.japonicus from 1978 to 2013.The results showed that there were interannual differences in the transport and distribution of eggs,larvae and juveniles of S.japonicus in the ECS due to different physical environments from 1978 to 2013,and this difference was extremely obvious in some specific years.The current in the drift path of eggs and juveniles controlled and affected the transport process and distribution characteristics.In April,the distribution of eggs and larvae was mainly controlled by the Taiwan Warm Current(TWC).The number of eggs and larvae transported into the northeastern waters of the ECS was positively correlated with the intensity of TWC.In May,it was mainly regu-lated by the TWC and the Tsushima Strait Warm Current(TSWC).In June,the number of larvae and juveniles entering the Tsushima Strait and the Pacific Ocean was determined by the TSWC.In general,in the years with high number of larvae and juveniles into the Tsushima Strait,the catch of 0-year-old S.japonicus was also higher.In addition,the number of larvae and juveniles entering the Tsushima Strait in El Niño years was less than that in La Niña years.In July,the transport was mainly controlled by the Kuroshio Current(KC),and the eddy within the KC strongly affected its distribution. | YU Wei FENG Zhiping PAN Lingzhi GUAN Wenjiang ZHANG Yu LI Yuesong | 2022 | Journal of Ocean University of China2022，21，5： | 0 |
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