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| 1 | Corrosion Behavior and Protection Efficiency of 2024Al and SiC_p/2024Al Metal Matrix Composite显示文摘The corrosion resistance of 2024 Al and SiC particle reinforced 2024 Al metal matrix composite (SiCp/2024Al MMC)in 3.5% NaCl solution was investigated with electrochemical method and immersion test, and the corrosion protection of sulfuric acid anodized coatings on both materials was evaluated by electrochemical impedance spectroscopy. The results showed that the SiCp/2024Al MMC is more susceptible to corrosion than its matrix alloy in 3.5% NaCl.For 2024Al, the anodized coating provides excellent corrosion resistance to 3.5% NaCl. The anodized coating on the SiCp/2024Al provides satisfactory corrosion protection, but it is not as effective as that for 2024Al because the structure of the anodized layer is affected by the SiC particulates. | Chunlin HE, Changsheng LIU, Fengqin LI and Qingkui CAISchool of Materials and Metallurgy, Northeastern University, Shenyang 110004, ChinaZhiming SHI, Liqing CHEN and Jing BIInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China | 2002 | Journal of Materials Science & Technology2002，18，4： | 2 |
| 2 | Tea polyphenols inhibit the growth and angiogenesis of breast cancer xenografts in a mouse model显示文摘Objective:To investigate the anti-angiogenic effect of tea polyphenols(TPS)on breast cancer and normal tissues in a mouse model.Methods:Breast cancer was successfully implanted into 48 BALB/c mice,which were then randomly divided into a TP oral gavage group,a TP local injection group,a ginsenoside Rg3 group,and a model control group according to a random number table.The tumor inhibitory rates of each group were calculated,while microvessel density(MVD)and the expression of vascular endothelial growth factor(VEGF),basic fibroblast growth factor(bFGF),and tissue inhibitor of metalloproteinase(TIMP-2)were detected by immunohistochemistry.Results:TPs could inhibit the growth of breast cancer xenografts in the mouse model.The tumor inhibition rates of the TP oral gavage and TP local injection groups were 37.43%and 40.94%,respectively.Compared with the model control group,MVD and VEGF and bFGF expression was downregulated(all P<.05),whereas TIMP-2 expression was elevated in the TP oral gavage and TP local injection groups(P=.015 and P=.032).TPs showed no significant effect on MVD and VEGF and TIMP-2 expression in the heart,brain,and kidney of the mouse model.Conclusion:TPs can restrict the growth of breast cancer by specifically inhibiting the angiogenesis of breast tumor tissue while having little effect on the normal tissue of important organs including the heart,brain,and kidney. | Peng Lv Fengqin Shi Xinyi Chen Li Xu Chong Wang Shaodan Tian Heng Yang Li Hou | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，2： | 2 |
| 3 | Tunable single-frequency intracavity frequency-doubled Ti:sapphire laser aroud 461 nm显示文摘 | Li Fengqin Shi Zhu Li Yongmin | 2011 | Chin Opt Lett2011，28，12： | 1 |
| 4 | The experimental study of Xue Guan Tong on preventing restenosis after percutaneous transluminal angioplasty 显示文摘 | Shi Dazhuo Xu Fengqin Ma Xiaochang | 1995 | Chinese Journal of Integrated Traditional and Westerm Medicine1995，1，： | 1 |
| 5 | Aberrant DNA methylation of miR‐219 promoter in long‐term night shiftworkers显示文摘 | Fengqin Shi Xinyi Chen Alan Fu Johnni Hansen Richard Stevens Anne Tjonneland Ulla B. Vogel Tongzhang Zheng Yong Zhu | 2013 | Mutagen2013，，6： | 1 |
| 6 | Aberrant DNA methylation of miR‐219 promoter in long‐term night shiftworkers显示文摘 | Fengqin Shi Xinyi Chen Alan Fu Johnni Hansen Richard Stevens Anne Tjonneland Ulla B. Vogel Tongzhang Zheng Yong Zhu | 2013 | Environ Mol Mutagen2013，，6： | 1 |
| 7 | Determination of Nine Phenolic Components in Leaves of Crataegus pinnatifida Bge.显示文摘[Objectives] To determine the nine phenolic components in the leaves of Crataegus pinnatifida Bge. [Methods] The reversedphase high-performance liquid chromatography( RP-HPLC) was applied. [Results] Nine phenolic components showed a good linear relationship in the range of 2-500 μg/m L with r in the range of 0. 999 5-0. 999 9. The recovery rate of spiked samples ranged from 93. 7% to110. 2%,and the relative standard deviation was in the range of 0. 69%-4. 58%. The leaves of 29 cultivars of C. pinnatifida Bge. were measured,and the average content of the nine phenolic components was as follows: isoquercitrin,hyperoside,procyanidin C1,procyanidin D1,epicatechin,procyanidin B2,chlorogenic acid,eucomic acid,and vitexin 2 '-O-rhamnoside. The contents of flavonoids and phenolic acids were high,up to 15 mg/g D. W,and the content of procyanidins was up to 6 mg/g D. W. [Conclusions]This method is easy and accurate in determination of phenolic components in the leaves of C. pinnatifida Bge. | Lei SHI Xiaobo YANG Zhe GAO Yanan JIA Zhenliang BI Fengqin LU Tong CUI | 2018 | Medicinal Plant2018，9，2： | 0 |
| 8 | Modified Liangfu granule exhibits anti-cancer effects in gastric cancer by regulating apoptosis-related proteins and genes显示文摘Objective:To investigate the anti-cancer effects and mechanism of modified Liangfu granule(MLFG)in BGC-823 gastric cancer cells.Methods:The drug serum was extracted from abdominal aorta of Wistar rats treated by cyclophosphamide,dioscin,MLFG(high-,medium-,and low-dose),respectively.MTS assay was performed to detect the effect of different concentrations of MLFG and dioscin on cell growth.The effect of MLFG on cellular apoptosis was detected by flow cytometry.Western blot was used to examine Bcl-2 and Akt in BGC-823 cells treated with MLFG.Quantitative real-time polymerase chain reaction assay was performed to determine the expression level of caspase-3,E2F1 and E2F3 genes in cells treated by MLFG-and dioscin-containing serum.Results:MLFG-and dioscin-containing serum inhibited the cell proliferation of BGC-823 cells.MLFG induced gastric carcinoma cell apoptosis and inhibited the expression of Bcl-2 and Akt in a dosedependent manner.MLFG also significantly induced the gene expression of caspase-3 and downregulated E2F1 and E2F3 gene expression.Conclusion:The effect of MLFG and dioscin on inhibiting cell proliferation and induction of apoptosis of gastric cancer cells might be related to the regulation of Bcl-2 and Akt proteins and the expression of caspase-3,E2F1 and E2F3 genes. | Ya Li Lingqun Zhu Fengqin Shi Ruibai Li Xinyi Chen Zhi Zheng Bin Qiu Li Hou | 2019 | Journal of Traditional Chinese Medical Sciences2019，6，4： | 0 |
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