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4篇 您的检索式:作者名="Fengxia YIN"
    题名 作者 年代 出处 被引量
1Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations显示文摘Jing Chen Wenzhao Wang Shen Lv Peiyuan Yin Xinjie Zhao Xin Lu Fengxia Zhang Guowang Xu 2009Analytica Chimica Acta2009,,1:1
2In vivo and in vitro development of Tibetan antelope(Pantholops hodgsonii)interspecific cloned embryos显示文摘The Tibetan antelope is endemic to the Tibetan Plateau,China,and is now considered an endangered species.As a possible rescue strategy,the development of embryos constructed by interspecies somatic cell nuclear transfer(iSCNT)was examined.Tibetan antelope fibroblast cells were transferred into enucleated bovine,ovine and caprine oocytes.These cloned embryos were then cultured in vitro or in the oviducts of intermediate animals.Less than 0.5%of the reconstructed antelope-bovine embryos cultured in vitro developed to the blastocyst stage.However,when the cloned antelope-bovine embryos were transferred to caprine oviducts,about 1.6%of the embryos developed to the blastocyst stage.In contrast,only 0.7%of the antelope-ovine embryos developed to the morula stage and none developed to blastocysts in ovine oviducts.The treatment of donor cells and bovine oocytes with trichostatin A did not improve the embryo development even when cultured in the oviducts of ovine and caprine.When the antelope-bovine embryos,constructed from oocytes treated with roscovitine or trichostatin A,were cultured in rabbit oviducts 2.3%and 14.3%developed to blastocysts,respectively.It is concluded that although some success was achieved with the protocols used,interspecies cloning of Tibetan antelope presents difficulties still to be overcome.The mechanisms resulting in the low embryo development need investigation and progress might require a deeper understanding of cellular reprogramming.Guanghua SU Lei CHENG Yu GAO Kun LIU Zhuying WEI Chunling BAI Fengxia YIN Li GAO Guangpeng LI Shorgan BOU 2014Frontiers of Agricultural Science and Engineering2014,1,1:1
3Classification and Prediction of Skyrmion Material Based on Machine Learning显示文摘The discovery and study of skyrmion materials play an important role in basic frontier physics research and future information technology.The database of 196 materials,including 64 skyrmions,was established and predicted based on machine learning.A variety of intrinsic features are classified to optimize the model,and more than a dozen methods had been used to estimate the existence of skyrmion in magnetic materials,such as support vector machines,k-nearest neighbor,and ensembles of trees.It is found that magnetic materials can be more accurately divided into skyrmion and non-skyrmion classes by using the classification of electronic layer.Note that the rare earths are the key elements affecting the production of skyrmion.The accuracy and reliability of random undersampling bagged trees were 87.5%and 0.89,respectively,which have the potential to build a reliable machine learning model from small data.The existence of skyrmions in LaBaMnO is predicted by the trained model and verified by micromagnetic theory and experiments.Dan Liu Zhixin Liu JinE Zhang Yinong Yin Jianfeng Xi Lichen Wang JieFu Xiong Ming Zhang Tongyun Zhao Jiaying Jin Fengxia Hu Jirong Sun Jun Shen Baogen Shen 2023Research2023,,4:0
4Oocyte-associated transcription factors in reprogramming after somatic cell nuclear transfer:a review显示文摘Oocytes are unique cells with the inherent capability to reprogram nuclei.The reprogramming of the somatic nucleus from its original cellular state to a totipotent state is essential for term development after somatic cell nuclear transfer.The nuclear-associated factors contained within oocytes are critical for normal fertilization by sperm or for somatic cell nuclear reprogramming.The chromatin of somatic nuclei can be reprogrammed by factors in the egg cytoplasm whose natural function is to reprogram sperm chromatin.The oocyte first obtains its reprogramming capability in the early fetal follicle,and then its capacity is enriched in the late growth phase and reaches its highest capability for reprogramming as fully-grown germinal vesicle oocytes.The cytoplasmic milieu most likely contains all of the specific transcription and/or reprogramming factors necessary for cellular reprogramming.Certain transcription factors in the cytoplast may be critical as has been demonstrated for induced pluripotent stem cells.The maternal pronucleus exerts a predominant,transcriptiondependent effect on embryo cytofragmentation,with a lesser effect imposed by the ooplasm and the paternal pronucleus.With deep analysis of transcriptomics in oocytes and early developmental stage embryos more maternal transcription factors inducing cellular reprogramming will be identified.Fengxia YIN Hui LIU Shorgan BOU Guangpeng LI 2014Frontiers of Agricultural Science and Engineering2014,1,2:0
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