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| 1 | Active tectonic blocks and strong earthquakes in the continent of China显示文摘The primary pattern of the late Cenozoic to the present tectonic deformation of China is characterized by relative movements and interactions of tectonic blocks. Active tectonic blocks are geological units that have been separated from each other by active tectonic zones. Boundaries between blocks are the highest gradient of differential movement. Most of tectonic activity occurs on boundaries of the blocks. Earthquakes are results of abrupt releases of accumulated strain energy that reaches the threshold of strength of the earth's crust. Boundaries of tectonic blocks are the locations of most discontinuous deformation and highest gradient of stress accumulation, thus are the most likely places for strain energy accumulation and releases, and in turn, devastating earthquakes. Almost all earthquakes of magnitude greater than 8 and 80%-90% of earthquakes of magnitude over 7 occur along boundaries of active tectonic blocks. This fact indicates that differential movements and interactions of active tectonic blocks are the primary mechanism for the occurrences of devastating earthquakes. | ZHANG Peizhen (张培震) DENG Qidong (邓起东) ZHANG Guomin (张国民) MA Jin (马 瑾) GAN Weijun (甘卫军) MIN Wei (闵 伟) MAO Fengying (毛凤英) WANG Qi (王 琪) | 2003 | Science China Earth Sciences2003，46，z2： | 239 |
| 2 | Paleoearthquake rupture behavior and recurrence of great earthquakes along the Haiyuan fault, northwestern China显示文摘The Haiyuan fault is a major seismogenic fault in north-central China where the 1920 Haiyuan earthquake of magnitude 8.5 occurred, resulting in more than 220000 deaths. The fault zone can be divided into three segments based on their geometric patterns and associated geomorphology. To study paleoseismology and recurrent history of devastating earthquakes along the fault, we dug 17 trenches along different segments of the fault zone. Although only 10 of them allow the paleoearthquake event to be dated, together with the 8 trenches dug previously they still provide adequate information that enables us to capture major paleoearthquakes oc- curring along the fault during the past geological time. We discovered 3 events along the eastern segment during the past 14000 a, 7 events along the middle segment during the past 9000 a, and 6 events along the western segment during the past 10000 a. These events clearly depict two temporal clusters. The first cluster occurs from 4600 to 6400 a, and the second occurs from 1000 to 2800 a, approximately. Each cluster lasts about 2000 a. Time period between these two clus- ters is also about 2000 a. Based on fault geometry, segmentation pattern, and paleoearthquake events along the Haiyuan fault we can identify three scales of earthquake rupture: rupture of one segment, cascade rupture of two segments, and cascade rupture of entire fault (three segments). Interactions of slip patches on the surface of the fault may cause rupture on one patch or ruptures of more than two to three patchs to form the complex patterns of cascade rupture events. | ZHANG Peizhen MIN Wei DENG Qidong MAO Fengying | 2005 | Science China Earth Sciences2005，48，3： | 31 |
| 3 | Coordinated regulation of apical hook development by gibberellins and ethylene in etiolated Arabidopsis seedlings显示文摘当在土壤发芽时,当通过土壤耸出时,黑暗成年的 Arabidopsis 幼苗开发一个顶端的钩,它保护子叶和顶端的 meristematic 纸巾。几荷尔蒙被报导清楚地调制这个过程。以前的研究证明了乙烯和赤霉素(气体) 并列地调整钩发展,尽管内在的分子的机制大部分是未知的。当 paclobutrazol 镇压了时,这里,我们显示出提高的那 GA 3 ethylene-overexpression 和 EIN3-overexpression (EIN3ox ) 导致了钩弯曲,并且 della 异种展出了夸大的钩弯曲,它要求了发信号的未经触动的乙烯小径。基因学习表明那提高 GA 的钩开发依赖于无钩 1 (HLS1 ) ,调停的一个中央管理者多重发信号小径的输入在顶端的钩开发期间。我们进一步发现那 GA 3 导致(并且 DELLA 蛋白质镇压了) 在乙烯感觉迟钝的 3/EIN3-LIKE 的 HLS1 表示 1 (EIN3/EIL1 ) 依赖举止, EIN3/EIL1 由此激活 HLS1 抄写由对它的倡导者直接有约束力。另外, DELLA 蛋白质被发现与 EIN3/EIL1 的 DNA 有约束力的领域交往并且镇压 EIN3/EIL1-regulated HLS1 表示。有 naphthylphthalamic 酸的处理,一个极的植物生长素运输禁止者,镇压 EIN3ox 线的组成地夸大的钩弯曲和 della 异种,支持那植物生长素在钩开发乙烯和 GA 小径下游地工作。一起拿,我们的结果作为联系 DELLA 的抄写因素的一个新类识别 EIN3/EIL1 并且证明 GA 由经由 EIN3/EIL1 函数的 derepression 导致 HLS1 的表达式部分与乙烯在合作支持顶端的钩形成。 | Fengying An Xing Zhang Ziqiang Zhu Yusi Ji Wenrong He Zhiqiang Jiang Mingzhe Li Hongwei Guo | 2012 | Cell Research2012，22，5： | 34 |
| 4 | The Arabidopsis PARAQUAT RESISTANT2 gene encodes an S-nitrosoglutathione reductase that is a key regulator of cell death显示文摘S-nitrosoglutathione (GSNO ) 的新陈代谢,主要生物学上活跃的氮的氧化物(没有) 种类,被进化地保存的 GSNO reductase (GSNOR ) 催化。以前的研究证明 Arabidopsis GSNOR1/HOT5 基因调整水杨酸酸由 modulating 发信号和 thermotolerance 细胞内部的 S-nitrosothiol 水平。这里,我们报导 Arabidopsis paraquat resistant2-1 (par2-1 ) 的描述显示出反房间死亡显型的异种。当由 paraquat (1,1'-dimethyl-4,4'-bipyridinium 二氯化物) 对待时,在 par2-1 的 superoxide 的生产比得上野类型的植物的,建议 PAR2 调整房间死亡的 superoxide 下游地行动。PAR2,由位置的克隆识别了,被显示与 GSNOR1/HOT5 相同。par2-1 异种在高度保存的 glycine 带一个错误感觉变化,它使变异的蛋白质变为不稳定。比作野类型, par2-1 异种有一不更高铺平,由与 4,5-diaminofluorescein diacetate 染色揭示了。与这结果一致,对待与的野类型的植物一没有施主显示抵抗到 paraquat。有趣地, GSNOR1/HOT5/PAR2 蛋白质水平除它的不变的 mRNA 水平以外,被 paraquat 导致,但是被没有施主减少。一起拿,这些结果建议 GSNOR1/HOT5/PAR2 在通过 modulating 在植物房间调整房间死亡起一个重要作用细胞内部没有水平。 | Ruiqiang Chen Shulan Sun Chun Wang Yansha Li Yan Liang Fengying An Chao Li Haili Dong Xiaohui Yang Jian Zhang Jianru Zuo | 2009 | Cell Research2009，19，12： | 14 |
| 5 | Oscillation characteristics of summer precipitation in the Huaihe River valley and relevant climate background显示文摘Based on the summer precipitation data from the Huaihe River valley and the middle and lower reaches of the Yangtze River from 1922 to 2007,we analyzed the interannual and interdecadal oscillation and probability distribution characteristics of summer precipitation in the Huaihe River valley during the same period,using the wavelet transform and generalized extreme distribution methods.Whereby,we studied the climate background of East Asia Summer Monsoon (EASM),Sea Surface Temperature (SST),East Asia telecorrelation circulation,and their relationship with the interannual and interdecadal oscillation of summer precipitation in the Huaihe River valley.We further compared the difference of interdecadal oscillation of summer precipitation and the relevant climate background between the Huaihe River valley and the middle and lower reaches of the Yangtze River.The results show that:1) The intensity change of quasi-biennial oscillation (QBO) of summer precipitation in the Huaihe River valley is consistent with that of interdecadal oscillation.The summer precipitation in the Huaihe River valley has been more than normal since the end of the 1990s,and the QBO is very significant.Meanwhile,the probability of occurrence of extreme heavy rainfall increased obviously.2) The interdecadal oscillation of summer precipitation in the Huaihe River valley has a close relationship with the Pacific Decadal Oscillation (PDO) and interdecadal oscillation of EASM.When PDO is in the cold phase and EASM weakens,the summer precipitation will be greater than normal.3) QBO of summer precipitation in the Huaihe River valley is mainly controlled by that of EASM,and it has a relationship with a circulation pattern of 'positive-negative-positive' from the high to the low latitudes in East Asia.4) There is interdecadal phase difference in summer precipitation between the Huaihe River valley and the middle and the lower reaches of the Yangtze River,which is mainly related to the intensity and position of West Pacific subtropical high. | FengYing Wei Ting Zhang | 2010 | Science China Earth Sciences2010，53，2： | 13 |
| 6 | In vitro anti-cancer activity of chamaejasmenin B and neochamaejasmin C isolated from the root of Stellera chamaejasme L显示文摘 | Chong ZHANG Shuang-shuang ZHOU Lin-yi FENGI Da-yong ZHANG Neng-ming LIN Li-huang ZHANG Jian-ping PAN Jun-bo WANG Jie LI | 2013 | Acta Pharmacologica Sinica2013，34，2： | 9 |
| 7 | Exploring the driving factors and their mitigation potential in global energy-related CO2 emission显示文摘In order to quantify the contribution of the mitigation strategies,an extended Kaya identity has been proposed in this paper for decomposing the various factors that influence the CO2 emission.To this end,we provided a detailed decomposition of the carbon intensity and energy intensity,which enables the quantification of clean energy development and electrification.The logarithmic mean divisia index(LMDI)has been applied to the historical data to quantify the contributions of the various factors affecting the CO2 emissions.Further,the global energy interconnection(GEI)scenario has been introduced for providing a systematic solution to meet the 2℃goal of the Paris Agreement.By combining LMDI with the scenario analysis,the mitigation potential of the various factors for CO2 emission has been analyzed.Results from the historical data indicate that economic development and population growth contribute the most to the increase in CO2 emissions,whereas improvement in the power generation efficiency predominantly helps in emission reduction.A numerical analysis,performed for obtaining the projected future carbon emissions,suggests that clean energy development and electrification are the top two factors that can decrease CO2 emissions,thus showing their great potential for mitigation in the future.Moreover,the carbon capture and storage technology serves as an important supplementary mitigation method. | Zhiyuan Ma Shining Zhang Fangxin Hou Xin Tan Fengying Zhang Fang Yang Fei Guo | 2020 | Global Energy Interconnection2020，3，5： | 9 |
| 8 | DELLA proteins interact with FLC to repress flowering transition显示文摘Flowering is a highly orchestrated and extremely ct critical process in a plant's life cycle. Previous study has ademonstrated that SUPPRESSOR OF OVEREXPRESSION OF pCONSTANS 1(SOC1) and FLOWERING LOCUS T(FT) integrate m-I the gibberellic acid(GA) signaling pathway and vernalization higpathway in regulating flowering time, but detailed molecular Hmechanisms remain largely unclear. In GA signaling pathway,DELLA proteins are a group of master transcriptional regulators, while in vernalization pathway FLOWERING LOCUS C(FLC) is a core transcriptional repressor that down-regulates the expression of SOC1 and FT. Here, we report that DELLA proteins interact with FLC in vitro and in vivo, and the LHRI domains of DELLAs and the C-terminus of MADS domain of FLC are required for these interactions.Phenotypic and gene expression analysis showed that mutation of FLC reduces while over-expression of FLC enhances the GA response in the flowering process. Further,DELLA-FLC interactions promote the repression ability of FLC on its target genes. In summary, these findings report that the interaction between MADS box transcription factor FLC and GRAS domain regulator DELLAs may integrate various signaling inputs in flowering time control, and shed new light on the regulatory mechanism both for FLC and DELLAs in regulating gene expression. | Mingzhe Li Fengying An Wenyang Li Mengdi Ma Ying Feng Xing Zhang Hongwei Guo | 2016 | Journal of Integrative Plant Biology2016，58，7： | 7 |
| 9 | Differentiation of rat iPS cells and ES cells into granulosa cell-like cells in vitro显示文摘早熟的卵巢的失败(POF ) 是卵巢的滤泡的早熟的弄空在 40 岁前描绘的一个卵巢的缺点,代表女不孕的一个主要原因。干细胞为 POF 提供一个潜在的处理的可能性。在这研究,老鼠胚胎的干细胞(转换字符) 和导致的 pluripotent 干细胞(iPSCs ) 与 granulosa 房间(GC ) 是 co 有教养的区分到象 GC 一样房间。放射性免疫测定分析的 estradiol (E2 ) 的水平证明 co 有教养的老鼠 iPSCs 和转换字符的文化上层清液的 E2 集中以一种时间依赖者方式增加了,与有一个相反的趋势的 GC 组相比。刺激滤泡的荷尔蒙受体(FSHR ) 的表示被 immunostaining 证实。这些结果显示了那老鼠 iPSCs,转换字符有效地通过间接 cell-to-cell 接触被导致到象 GC 一样房间。实时聚合酶链反应被执行在 POF 分析标记基因的表示水平,包括 BMP15, FMR1, FSHR, INHA, AMH, NOBOX, FOXO3, EIF2B, FIGLA,和 GDF9。BMP15, FSHR, INHA, AMH, NOBOX,和 GDF9 基因在 iPSCs 和与与不是 co 有教养的房间比较的 GC co 有教养的转换字符是显著地起来调整的。因此,这里,我们表明了一个可得到的方法为 POF 的可能的房间治疗在 vitro 区分老鼠 iPSCs 和转换字符进象 GC 一样房间。 | Juan Zhang Hui Li Zhao Wu XiaoJun Tan Fengying Liu Xianghong Huang Xiaoling Fang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，4： | 7 |
| 10 | Secreted Frizzled-Related Protein 5 (SFRP5) in Patients with Obstructive Sleep Apnea显示文摘Objective Obstructive sleep apnea (OSA) is closely related to obesity, insulin resistance and inflammation. Secreted frizzled-related protein 5 (SFRP5) is a recently discovered adipokine. It is involved in insulin resistance and inflammation in obesity. This study aimed at evaluating the association between SFRP5and sleeping characteristics as well as biochemical parameters of OSA patients.Methods This was a prospective case control study. Nondiabetic OSA patients and controls were consecutively recruited and divided into three groups: OSA group, apnea–hypopnea Index (AHI)≥5/h; healthy controls with normal body mass index (BMI); obese controls without OSA, and BMI > 24.0 kg/m2. All participants underwent polysomnography (PSG). Plasma SFRP5 was examined using enzyme-linked immunosorbent assay (ELISA). Blood biochemical examinations, including fasting blood glucose (FBG), lipid profile, hypersensitive Creactive protein (hsCRP), were performed early in the morning after PSG. Patients with severe OSA were treated with nasal continuous positive airway pressure (nCPAP), and plasma SFRP5 was repeatedly measured for comparison.Results Sixty-eight subjects were enrolled in the study, including 38 patients of OSA, whose medium AHI was 58.70 /h (36.63, 71.15), 20 obese controls, and 10 healthy controls. The plasma SFRP5 level of OSA patients was not significantly different from that of healthy controls or obese controls. In OSA patients, SFRP5 level correlated positively with triglyceride level (r=0.447, P=0.005) and negatively with LDL-cholesterol level and HDLcholesterol level (r=?0.472 and P=0.003; r=?0.478 and P=0.002; respectively). SFRP5 level was not found correlating with FBG, AHI, or any of nocturnal hypoxia parameters. After overnight nCPAP treatment, plasma SFRP5 levels of OSA patients did not change significantly (t=1.557, P = 0.148) compared to that of pretreatment.Conclusions In nondiabetic OSA patients, plasma SFRP5 is associated with the lipid profile. However,no correlation was observed between SFRP5 and FBG or sleep parameters. The SFRP5 level of OSA patients did not differ from that of non-OSA individuals in our study. | Dongmei Zhang Rong Huang Yi Xiao Fengying Gong Xu Zhong Jinmei Luo | 2017 | Chinese Medical Sciences Journal2017，32，4： | 7 |
| 11 | Perception of people for the risk of Tianwan nuclear power plant显示文摘A questionnaire survey of residents’risk perceptions related to Taiwan nuclear power plant in China was carried out to explore the determining factors that affect individual risk perception.This study proposed to pursue a more comprehensive understanding of factors that affected individual risk perception to nuclear power plants.Covariance structure analysis was conducted using risk perceptions of nuclear power as dependent variable and including interest and knowledge levels of nuclear power,acceptability,benefit perception,trust in nuclear power operation,and trust in government as independent variables.The use of the hypothesis of Elaboration likelihood model(ELM)was also proposed.The results showed that persons with higher levels of interest and knowledge of nuclear power had their own perceptions of risk closely associated with acceptability and potential benefits of nuclear power.In contrast,persons with no interest in and knowledge of nuclear power would have risk perceptions related to their trust in nuclear operation and the government,which partially supported the ELM hypothesis.All these results indicated that the government in China plays an important role in rational risk perceptions,and well-designed communication of risks will help the public to be involved in risk management and improve people’s rational acceptance of risk. | Lei HUANG Jun BI Bing ZHANG Fengying LI Changsheng QU | 2010 | Frontiers of Environmental Science & Engineering2010，4，1： | 6 |
| 12 | Effects of soaking process on arsenic and other mineral elements in brown rice显示文摘One of the main food crops in the world,rice can accumulate high levels of arsenic from flooded paddy soils,which seriously threatens human health.Soaking,a common processing method for brown rice products,especially for brown rice noodles,was investigated in this study.Japonica rice(Dao Hua Xiang No.2)and Indica rice(Ye Xiang You No.3)were selected for studying the effects of soaking on arsenic concentrations,species,and distributions.Results revealed that soaking can efficiently remove arsenic in these two rice varieties,and the main part of removal is endosperm with the maximal rate of about 40%.Inorganic arsenic(I-As)(about 85%)is the main species of arsenic reduction.Meanwhile,the variations of four other elements(i.e.,Mg,Ca,Zn,and Fe)were analyzed.Collectively,the findings of this study indicate that soaking can efficiently remove arsenic in brown rice under controlled soaking conditions,which thereby reduces the arsenic intake for brown rice customers. | Fan Zhang Fengying Gu Huili Yan Zhenyan He Bolun Wang Hao Liu Tingting Yang Feng Wang | 2020 | Food Science and Human Wellness2020，9，2： | 5 |
| 13 | Species composition,diversity and density of plagic Ostracoda in the East China Sea显示文摘On the basis of seasonal investigations at 23°30'~33°00'N,118°30'~128°00'E of the East China Sea during 1997~2000,dynamics on the density and diversity of Ostracoda was discussed.Results showed that totally 26 species were identified.The Ostracoda diversity was opposite to the change of its density in most seasons which reflected an uneven assignment of Ostracoda density among its different species.The Ostracoda density was 0.70 ind./m3 in spring,1.72 ind./m3 in summer,2.57 ind./m3 in autumn and 0.90 ind./m3 in winter.Euconchoecia chierchiae in spring and winter,Euconchoecia maimai in summer and Cypridina dentata in autumn were main dominant species in each season.The Ostracoda density did not show an obvious linear relationship with the hydrologic factors in summer and autumn,but was related to the surface salinity in spring and the surface temperature in winter.Its high density areas mainly distributed in the north offshore in all the seasons while in the south offshore in winter and in spring,and the south nearshore in summer and autumn,implied the zooplankton was a typical warm water animal,whose high density distribution in autumn were located in a similar position to Todarodes pacificus,Navodon Septentrionalis,Scomber japonicus and other fishes in the sea,so as to be an important indicator for fishing ground.The main species dominating in Ostracoda now are different from the species twenty years ago probably attributes to global warming. | XU Zhaoli GU Xiaolian ZHANG Fengying | 2007 | Acta Oceanologica Sinica2007，26，5： | 4 |
| 14 | The potential role of retinoic acid receptor on glomerulosclerosis in rats and podocytes injury is associated with the induction of MMP2 and MMP9显示文摘Retinoic 酸受体(RAR ) 在肾疾病起一个关键作用。然而,在 glomerulosclerosis (GS ) 的内在的机制仍然不是清楚的。在 adriamycin (ADR ) 的 RAR 的角色劝诱了 GS 老鼠模型,在导致 ADR 的 podocyte,在 vitro 的损害被调查。RAR 在 GS 老鼠是过去表示的,并且浆液,尿和肾样品是镇定的检测受体的表示的正式就职。RAR 表示被禁止或在跟随损害,由 morphometric 试金示威了的有教养的 podocytes 过去表示房间毒性,和矩阵 metalloproteinase (MMP ) 酶的活动。RAR 在 GS 老鼠显示了一个 renoprotective 角色,导致一个更低的 GS 索引, podocyte 脚过程熔化,和 proteinuria,减少的浆液 creatinine 和血脲氮。进一步的实验显示 RAR 禁止了 TGF-1,光滑的肌肉肌动朊,骨胶原 IV,和 fibronectin 的累积,当它导致了 MMP2 和 MMP9 时在在 vitro 的 podocytes 的过多的表示。RAR 改进了肾的功能并且稀释了与 MMP2 和 MMP9 的在表示上被联系的 GS 的前进。 | Xiuping Chen Yuanhan Qin Tianbiao Zhou Ling Jiang Fengying Lei He Qin Lei Zhang Zhiqiang Zhou | 2017 | Acta Biochimica et Biophysica Sinica2017，49，8： | 3 |
| 15 | Overcoming the limitation of in-situ microstructural control in laser additive manufactured Ti-6Al-4V alloy to enhanced mechanical performance by integration of synchronous induction heating显示文摘Although a variety of processing routes were developed to in-situ manipulate microstructure for fabricating high-performance Ti-6Al-4 V alloy by directed energy deposition(DED),the in-situ microstructural control ability has been limited and lead to a narrowed mechanical property control range.This work proved the microstructural correlation betweenβ-grains andα-laths resulting from the unique thermal characteristics of DED for the first time and solved such a dilemma through synchronous induction heating assisted laser deposition(SILD)technology.The results confirmed that the laser energy and inductive energy have a different effect on the solidification and solid phase transformation conditions.By adjusting the laser-induction parameters,the microstructural correlation can be tuned;theβ-grains andα-laths can be controlled relatively separately,thereby significantly enhancing the ductility of as-deposited sample(elongation from 14.2%to 20.1%).Furthermore,the mechanical properties of the tuned microstructures are even comparable to that of DED Ti-6Al-4 V with post heat treatment,which indicates that the potential of SILD to be a one-step manufacturing process to fabricate high performance components without post heat treatment.Furthermore,the tensile testing results of the tuned microstructures indicate thatα-lath size is more influential on the mechanical properties than theβ-grain size due to its stronger hindering effect on the slipping of dislocations.This work promotes the understanding of the microstructural formation mechanism in DED titanium alloy and proves that the combination of synchronous induction and laser can expand the ability to control the microstructure and properties of multi-layer deposition. | Wei Fan Hua Tan Fengying Zhang Zhe Feng Yongxia Wang Lai-Chang Zhang Xin Lin Weidong Huang | 2021 | Journal of Materials Science & Technology2021，，35： | 3 |
| 16 | Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway显示文摘The aberrant changes of fussion/fission-related proteins can trigger mitochondrial dynamics imbalance,which cause mitochondrial dysfunctions and result insulin resistance(IR).However,the relationship between the inner mitochondrial membrane fusion protein optic atrophy 1(Opa1)and hepatic IR as well as the specific molecular mechanisms of signal transduction has not been fully elucidated.In this study,we explore whether abnormalities in the Opa1 cause hepatic IR and whether berberine(BBR)can prevent hepatic IR through the SIRT1/Opa1 signalling pathway.High-fat diet(HFD)-fed mice and db/db mice are used as animal models to study hepatic IR in vivo.IR,morphological changes,and mitochondrial injury of the liver are examined to explore the effects of BBR.SIRT1/Opa1 protein expression is determined to confirm whether the signalling pathway is damaged in the model animals and is involved in BBR treatment-mediated mitigation of hepatic IR.A palmitate(PA)-induced hepatocyte IR model is established in HepG2 cells in vitro.Opa1 silencing and SIRT1 overexpression are induced to verify whether Opa1 deficiency causes hepatocyte IR and whether SIRT1 improves this dysfunction.BBR treatment and SIRT1 silencing are employed to confirm that BBR can prevent hepatic IR by activating the SIRT1/Opa1 signalling pathway.Western blot analysis and JC-1 fluorescent staining results show that Opa1 deficiency causes an imbalance in mitochondrial fusion/fission and impairs insulin signalling in HepG2 cells.SIRT1 and BBR overexpression ameliorates PA-induced IR,increases Opa1,and improves mitochondrial function.SIRT1 silencing partly reverses the effects of BBR on HepG2 cells.SIRT1 and Opa1 expressions are downregulated in the animal models.BBR attenuates hepatic IR and enhances SIRT1/Opa1 signalling in db/db mice.In summary,Opa1 silencing-mediated mitochondrial fusion/fission imbalance could lead to hepatocyte IR.BBR may improve hepatic IR by regulating the SIRT1/Opa1 signalling pathway,and thus,it may be used to treat type-2 diabetes. | Jia Xu Yining Zhang Zhiyi Yu Yueqi Guan Yuqian Lv Meishuang Zhang Ming Zhang Li Chen Xiaoyan Lv Fengying Guan | 2022 | Acta Biochimica et Biophysica Sinica2022，54，10： | 3 |
| 17 | Understanding the spatial representativeness of air quality monitoring network and its application to PM_(2.5)in the China's Mainland显示文摘Air pollution has seriously endangered human health and the natural ecosystem during the last decades.Air quality monitoring stations(AQMS)have played a critical role in providing valuable data sets for recording regional air pollutants.The spatial representativeness of AQMS is a critical parameter when choosing the location of stations and assessing effects on the population to long-term exposure to air pollution.In this paper,we proposed a methodological framework for assessing the spatial representativeness of the regional air quality monitoring network and applied it to ground-based PM_(2.5)observation in the mainland of China.Weighted multidimensional Euclidean distance between each pixel and the stations was used to determine the representativeness of the existing monitoring network.In addition,the K-means clustering method was adopted to improve the spatial representativeness of the existing AQMS.The results showed that there were obvious differences among the representative area of 1820 stations in the mainland of China.The monitoring stations could well represent the PM_(2.5)spatial distribution of the entire region,and the effectively represented area(i.e.the area where the Euclidean distance between the pixels and the stations was lower than the average value)accounted for 67.32%of the total area and covered 93.12%of the population.Forty additional stations were identified in the Northwest,North China,and Northeast regions,which could improve the spatial representativeness by 14.31%. | Ling Su Chanchan Gao Xiaoli Ren Fengying Zhang Shanshan Cao Shiqing Zhang Tida Chen Mengqing Liu Bingchuan Ni Min Liu | 2022 | Geoscience Frontiers2022，13，3： | 3 |
| 18 | Synthesis and characteriza-tion of two new types of oxovanadium complexes with pyrazole as ligand显示文摘At room temperature, two new different oxovanadium complexes with simple pyrazole (C3H4N2) as ligand were synthesized. VO(pz)4(SO4)? H2O (1) (pz: pyrazole) is a mono-nuclear oxovana- dium complex with pyrazole as terminal ligands. V2O2(μ-pz)(μ-OOSO2)(μ-OCH3)(pz)4 (2) is bi-nuclear oxovanadium complex containing three different bridges, which are pyrazolate, sulphate and methoxy, respectively. The two complexes were characterized by IR, elemental analyses, thermal analyses and X-ray diffraction. The crystal structural data of the complexes 1 and 2 are given as follows: Complex 1, orthorhombic, Pna21, a = 14.547(2) ?, b =10.895(2) ?, c =11.835(2) ?; α=β=γ=90°, V=1875.8(5) ?3, Z = 4, R1 = 0.0485, WR2 = 0.1092. Complex 2, triclinic, P1 , a =8.377(2) ?, b =9.928(2) ?, c = 16.527(3) ?, α = 85.54(3)°, β = 80.92(3)°, γ = 87.92(3)°, R1 = 0.1461, WR2 = 0.4444. The study of non-thermal kinetic de- composition shows that, for complex 1, the possible reaction mechanisms of the two steps are nucleation and growth n=1/3, and three-dimensional pervasion n=2, respectively, and the kinetic equations may be expressed as dα/dT = (A/β)exp(?E/RT){1/3(1?α) [?In(1?α)]?2} and dα/dT = (A/β)exp(?E/RT){3/2(1?α)2/3 [1?(1?α)1/3] ?1}, respectively; for complex 2, the pos- sible reaction mechanisms of the two steps are chemical reaction, and three-dimensional pervasion n=2, respectively; the kinetic equations may be ex- pressed as dα/dT = (A/β)exp(?E/RT)[(1?α)2], anddα/dT = (A/β)exp(?E/RT){3/2(1?α)2/3[1?(1?α)1/3] ?1}, respectively. | XING Yongheng ZHANG Yuanhong XU Yongting ZHANG Baoli NIU Shuyun BAI Fengying | 2006 | Chinese Science Bulletin2006，51，18： | 3 |
| 19 | Formamidinium Lead Bromide (FAPbBr_3) Perovskite Microcrystals for Sensitive and Fast Photodetectors显示文摘Because of the good thermal stability and superior carrier transport characteristics of formamidinium lead trihalide perovskite HC(NH_2)_2 PbX_3(FAPbX_3), it has been considered to be a better optoelectronic material than conventional CH_3NH_3-PbX_3(MAPbX_3). Herein, we fabricated a FAPbBr_3 microcrystal-based photodetector that exhibited a good responsivity of 4000 A W-1 and external quantum efficiency up to 106% under one-photon excitation, corresponding to the detectivity greater than 1014 Jones. The responsivity is two orders of magnitude higher than that of previously reported formamidinium perovskite photodetectors. Furthermore, the FAPbBr_3 photodetector's responsivity to two-photon absorption with an 800-nm excitation source can reach 0.07 A W^(-1), which is four orders of magnitude higher than that of its MAPbBr_3 counterparts. The response time of this photodetector is less than 1 ms.This study provides solid evidence that FAPbBr_3 can be an excellent candidate for highly sensitive and fast photodetectors. | Fengying Zhang Bin Yang Kaibo Zheng Songqiu Yang Yajuan Li Weiqiao Deng Rongxing He | 2018 | Nano-Micro Letters2018，10，3： | 2 |
| 20 | Adenine Phosphoribosyl Transferase 1 is a Key Enzyme Catalyzing Cytokinin Conversion from Nucleobases to Nucleotides in Arabidopsis显示文摘在植物,细胞激动素包括细胞激动素生合成,互变现象, inactivation,和降级,新陈代谢的进程在细胞激动素动态平衡和植物开发的规定起关键作用。嘌呤新陈代谢的酶被暗示了在以前的工作催化细胞激动素互变现象。在这研究,我们报导腺嘌 Phosphoribosyl Transferase 1 (APT1 ) 是高剂量的细胞激动素抵抗的异种的原因的基因。APT1 从免费的底催化细胞激动素变换到核苷酸,并且在 Arabidopsis 腺嘌 Phosphoribosyl Transferase 家庭的五个成员之中是机能上地占优势的。在工厂的 APT1 活动的损失导致细胞激动素底的过量累积,因此唤起无数调整细胞激动素的回答例如推迟的叶老朽, anthocyanin 累积,和下游的基因表示。因此,我们的学习把 APT1 定义为由 phosphoribosylation 参予细胞激动素 inactivation 的关键新陈代谢的酶。 | Xinyan Zhang Yutao Chen Xin Lin Xinyu Hong Ying Zhu Wenyang Li Wenrong He Fengying An Hongwei Guo | 2013 | Molecular Plant2013，6，5： | 2 |
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