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6篇 您的检索式:作者名="Fernando Bello"
    题名 作者 年代 出处 被引量
1Impact of minimally invasive surgery on the treatment of benign esophageal disorders显示文摘Thanks to the development of minimally invasive surgery, the last 20 years have witnessed a change in the treatment algorithm of benign esophageal disorders. Today a laparoscopic operation is the treatment of choice for esophageal achalasia and for most patients with gastroesophageal reflux disease. Because the pathogenesis of achalasia is unknown, treatment is palliative and aims to improve esophageal emptying by decreasing the functional obstruction at the level of the gastro-esophageal junction. The refinement of minimally invasive techniques accompanied by large, multiple randomized control trials with long-term outcome has allowed the laparoscopic Heller myotomy and partial fundoplication to become the treatment of choice for achalasia compared to endoscopic procedures, including endoscopic botulinum toxin injection and pneumatic dilatation. Patients with suspected gastroesophageal reflux need to undergo a thorough preoperative workup. After establishing diagnosis, treatment for gastroesophageal reflux should be individualized to patient characteristics and a decision about an operation made jointly between surgeon and patient. The indications for surgery have changed in the last twenty years. In the past, surgery was often considered for patients who did not respond well to acid reducing medications. Today, the best candidate for surgery is the patient who has excellent control of symptoms with proton pump inhibitors. The minimally invasive approach to antireflux surgery has allowed surgeons to control reflux in a safe manner, with excellent long term outcomes. Like achalasia and gastroesophageal reflux, the treatment of patients with paraesophageal hernias has also seen a major evolution. The laparoscopic approach has been shown to be safe, and durable, with good relief of symptoms over the long-term. The most significant controversy with laparoscopic paraesophageal hernia repair is the optimal crural repair. This manuscript reviews the evolution of these techniques.Brian Bello Fernando A Herbella Marco E Allaix Marco G Patti 2012World Journal of Gastroenterology2012,18,46:6
2Reversion of advanced ebola virus disease in nonhuman primates with Zmapp显示文摘Qiu X Wong G Audet J Bello A Fernando L Alimonti JB Fausther-Bovendo H Wei H Aviles J Hiatt E Johnson A Morton J Swope K Bohorov O Bohorova N Goodman C Kim D Pauly M H Velasco J Pettitt J Olinger G G Whaley K Xu B Strong J E Zeitlin L Kobinger G P 2014Nature2014,514,7520:1
3Distributed simulation – Accessible immersive training显示文摘Roger Kneebone Sonal Arora Dominic King Fernando Bello Nick Sevdalis Eva Kassab Raj Aggarwal Ara Darzi Debra Nestel 2010Medical Teacher2010,,1:1
4Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp 显示文摘Qiu X Wong G Audet J Bello A Fernando L Alimonti JB Fausther-Bovendo H Wei H Aviles J Hiatt E Johnson A Morton J Swope K Bohorov O Bohorova N Goodman C Kim D Pauly MH Velasco J Pettitt J Olinger GG Whaley K Xu B Strong JE Zeitlin L Kobinger GP 2014Nature2014,514,7520:1
5Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp 显示文摘Qiu X Wong G Audet J Bello A Fernando L Alimonti J B 2014Nature2014,514,:1
6Current and future role of three-dimensional modelling technology in rectal cancer surgery:A systematic review显示文摘BACKGROUND Three-dimensional(3D)modelling technology translates the patient-specific anatomical information derived from two-dimensional radiological images into virtual or physical 3D models,which more closely resemble the complex environment encountered during surgery.It has been successfully applied to surgical planning and navigation,as well as surgical training and patient education in several surgical specialties,but its uptake lags behind in colorectal surgery.Rectal cancer surgery poses specific challenges due to the complex anatomy of the pelvis,which is difficult to comprehend and visualise.AIM To review the current and emerging applications of the 3D models,both virtual and physical,in rectal cancer surgery。METHODS Medline/PubMed,Embase and Scopus databases were searched using the keywords“rectal surgery”,“colorectal surgery”,“three-dimensional”,“3D”,“modelling”,“3D printing”,“surgical planning”,“surgical navigation”,“surgical education”,“patient education”to identify the eligible full-text studies published in English between 2001 and 2020.Reference list from each article was manually reviewed to identify additional relevant papers.The conference abstracts,animal and cadaveric studies and studies describing 3D pelvimetry or radiotherapy planning were excluded.Data were extracted from the retrieved manuscripts and summarised in a descriptive way.The manuscript was prepared and revised in accordance with PRISMA 2009 checklist.RESULTS Sixteen studies,including 9 feasibility studies,were included in the systematic review.The studies were classified into four categories:feasibility of the use of 3D modelling technology in rectal cancer surgery,preoperative planning and intraoperative navigation,surgical education and surgical device design.Thirteen studies used virtual models,one 3D printed model and 2 both types of models.The construction of virtual and physical models depicting the normal pelvic anatomy and rectal cancer,was shown to be feasible.Within the clinical context,3D models were used to identify vascular anomalies,for surgical planning and navigation in lateral pelvic wall lymph node dissection and in management of recurrent rectal cancer.Both physical and virtual 3D models were found to be valuable in surgical education,with a preference for 3D printed models.The main limitations of the current technology identified in the studies were related to the restrictions of the segmentation process and the lack of 3D printing materials that could mimic the soft and deformable tissues.CONCLUSION 3D modelling technology has potential to be utilised in multiple aspects of rectal cancer surgery,however,it is still at the experimental stage of application in this setting.Anna Przedlacka Gianluca Pellino Jordan Fletcher Fernando Bello Paris P Tekkis Christos Kontovounisios 2021World Journal of Gastrointestinal Surgery2021,13,12:1
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